Search clinical trials for: PALB2 mutation

Total 3284 results

New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Terminated

PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations

Schizophrenia

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRANSPORT)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, France, Spain, Belgium, Canada, Austria, Australia, Germany, United Kingdom, Denmark
Memorial Sloan Kettering Cancer Center
Cardiff Oncology

Completed

Detection of Oncogenic Tumor Mutations in the Urine and Blood of Lung and Colorectal Cancer Patients

Colorectal Cancer | Lung Cancer

United States
Massachusetts General Hospital
M.D. Anderson Cancer Center; Memorial Sloan Kettering Cancer Center; Dana-Farber...

Completed

Detecting EGFR T790M Mutations From Circulating Tumor Cells

Non Small Cell Lung Cancer

United States
University Hospital Center of Martinique

Completed

KRAS Mutation and Incidence of the Colorectal Carcinoma in Martinique Between 2007 and 2009 (KRAS)

Colorectal Carcinoma

France
Corporacion Parc Tauli

Completed

APPLICATION OF MOLECULAR TECHNIQUES FOR IMPROVING THE DIAGNOSIS AND TREATMENT OF NODULAR THYROID LESIONS.

Papillary Thyroid Carcinoma

Spain
AstraZeneca

Completed

Europe-Japan Diagnostic Study for EGFR Testing (ASSESS)

EGFR Mutation Status in aNSCLC Patients (Locally Advanced and/or Metastatic Disease) With Adenocarcinoma and Non-adenocarcinoma Histologies.

Italy, Spain, United Kingdom, Sweden, Japan, Netherlands, Germany, France
Sun Yat-sen University

Unknown

FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type (FORBES)

Metastatic Colorectal Cancer

China
SciClone Pharmaceuticals

Unknown

First Line Bio-immunotherapy With Thymosin Alpha 1 in Patients With Sensitizing EGFR Mutation Positive Non Small Cell Lung Cancer Who Are Taking Standard of Care Therapy

EGFR Mutation Positive Non Small Cell Lung Cancer

Italy
Loyola University

Withdrawn

Melatonin for Prevention of Post- Operative Delirium Pilot Study Protocol

Delirium

United States
Boehringer Ingelheim

Completed

LUX Lung 2 Phase II Single Arm BIBW 2992 "Afatinib" in NSCLC With EGFR Activating Mutations

Carcinoma, Non-Small-Cell Lung

United States, Taiwan
Hoffmann-La Roche

Completed

A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 Mutation

Neoplasms

United States, France, Italy, Netherlands
Fujian Cancer Hospital

Unknown

EGFR-TKIs Combine Chemotherapy as First-line Therapy for Patients With Advanced EGFR Mutation-positive NSCLC (effect)

EGFR Gene Mutation
Khoo Teck Puat Hospital

Completed

Sulphonylurea Receptor Mutation and Responsiveness to Gliclazide - a Pilot Proof of Concept, Randomised Cross-over Study

Diabetes

Singapore
Hospices Civils de Lyon

Completed

Molecular Genetics in Infantile Spasms

Infantile Spasms | West Syndrome
Daping Hospital and the Research Institute of Surgery...

Unknown

First-line Icotinib With Concurrent Radiotherapy for NSCLC With EGFR Mutation

Non-small Cell Lung Cancer
M.D. Anderson Cancer Center

Terminated

Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin (PI3K-mTOR) in Advanced Cancer Patients

Advanced Cancers

United States
Chang Gung Memorial Hospital
Sanofi

Unknown

Fabry Disease in Cerebrovascular Disease

Fabry Disease

Taiwan
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

EGFR-TKI With Chemotherapy in NSCLC Patients With Both EGFR Mutation and BIM Deletion Polymorphism

Non-Small-Cell Lung Cancer
Cynvenio Biosystems

Unknown

A Pilot Surveillance Study to Monitor Natural Killer Cells and Circulating Tumor Cells in Women With Previously Treated Non-metastatic Triple Negative Breast Cancer and Women With Previously Treated Non-metastatic Breast Cancer With a Confirmed BRCA Mutation.

Triple Negative Breast Cancer | BRCA Mutation | Natural Killer Cells

United States
Affiris AG
University Hospital Tuebingen

Withdrawn

Study Assessing Tolerability and Safety and Exploring the Immunogenicity and Therapeutic Activity of AFFITOPE® PD01A in PD-GBA Patients

Parkinson's Disease

Germany
Pamlab, Inc.
Massachusetts General Hospital

Completed

A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients

Schizophrenia

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Comparison of KRAS/BRAF Mutational Status With Conventional Techniques and Plasma Samples Analysis (KPLEX2)

Colorectal Cancer
Hospices Civils de Lyon

Unknown

Study of the Prevalence of Fabry Disease in French Dialysis Patients (FABRYDIAL)

End Stage Renal Disease | Fabry Disease | Renal Dialysis

France
The Alfred

Unknown

CPET in CF Patients With One G551D Mutation Taking VX770

Cystic Fibrosis

Australia
Hadassah Medical Organization
Soroka University Medical Center

Unknown

Ascorbic Acid Treatment in Congenital Glucocorticoids and Mineralocorticoids Deficiency Due to NNT Mutation

Glucocorticoids Deficiency

Israel
Alnylam Pharmaceuticals

Completed

DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis

Familial Amyloidotic Cardiomyopathy (FAC)

United States, France, Spain, United Kingdom, Belgium, Brazil
AstraZeneca

No longer available

AZD9291 US Expanded Access Program

EGFR T790M Mutation Positive NSCLC

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Gene Expression in Samples From Patients With Rhabdoid Tumors

Kidney Cancer | Brain and Central Nervous System Tumors
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors

Ovarian Cancer | Leydig Cell Tumor | Childhood Germ Cell Tumor
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy

Prostate Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma

Neuroblastoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Cancer

Sarcoma | Kidney Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Pleuropulmonary Blastoma | Hereditary Wilms Tumor
University Hospital, Toulouse

Completed

Responses to Chemotherapy of Patients With Non-small Cell Lung Cancer Harboring a Known Somatic Activating HER2 Mutation

Lung Cancer
Joint Authority for Päijät-Häme Social and Health...
Helsinki University Central Hospital

Completed

Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL

Actinic Keratoses

Finland
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Oxalosis...

Completed

Primary Hyperoxaluria Mutation Genotyping

Primary Hyperoxaluria

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gene Testing in Patients With Colon Cancer

Colorectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Genetic Trial to Study Diarrhea in Patients With Stage III Colon Cancer Who Are Receiving Chemotherapy

Diarrhea | Colorectal Cancer | Neutropenia

United States, Canada, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Prevalence of EGFR Mutations in Participants With NSCLC

Non-Small Cell Lung Cancer

Jordan
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Epidermal Growth Factor Receptor and K-ras Mutations in Patients With Stage III Non-Small Cell Lung Cancer

Lung Cancer
University of South Florida
Friedreich's Ataxia Research Alliance; Edison Pharmaceuticals Inc

Completed

EPI-743 in Friedreich's Ataxia Point Mutations

Friedreich's Ataxia

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Cancer Genome Study Using Samples From Patients With Stage I or Stage II Non-Small Cell Lung Cancer Treated on Clinical Trial ACOSOG-Z0030

Lung Cancer
McGill University Health Centre/Research Institute...
Children's Hospital and Medical Center, Omaha, Nebraska

Completed

Betaine and Peroxisome Biogenesis Disorders

Peroxisome Biogenesis Disorders

Canada
Bristol-Myers Squibb

Completed

Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

United States, Canada
University of Michigan Rogel Cancer Center
Augusta University

Withdrawn

Personalized Adaptive Radiation Therapy With Individualized Systemic Targeted Therapy (PARTIST) for Locally Advanced, Non-small Cell Lung Cancer With Genomic Driver Mutations

Non-Small Cell Lung Cancer

United States
CHU de Reims

Unknown

Mutations of Glucocorticoid Receptor in Bilateral Adrenal Hyperplasia (MUTA-GR)

General Glucocorticoid Resistance

France
National Heart Centre Singapore
Singapore General Hospital; Duke-NUS Graduate Medical School

Completed

Identification and Metabolic Characterization of a Cohort of Human Subjects With Mutations in PRDM-16

Obesity | Diabetes | Dyslipidemia | Mutation
Zhejiang Cancer Hospital

Unknown

Acquired Resistant Mechanism of the First-generation EGFR TKIs

Non-small Cell Lung Cancer | Aquired Resistance | EGFR TKIs

China
Peking Union Medical College Hospital

Unknown

A Multi-center Prospective Observational Biomarker Study on EGFRm+ Non-small Cell Lung Cancer Patients With Leptomeningeal Metastasis

Non-small Cell Lung Cancer | Leptomeningeal Metastasis

China
Women's College Hospital
Canadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaborators

Unknown

Cancer Prevention in Women With a BRCA Mutation

Breast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation

Canada

Search clinical trials for: PALB2 mutation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations