Clinical Trials Sponsored by Canadian Cancer Trials Group

Total 490 results

Canadian Cancer Trials Group
Merck Sharp & Dohme LLC; Intergroupe Francophone de Cancerologie Thoracique; National...

Active, not recruiting

Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma

Mesothelioma

France, Canada, Italy
Hamilton Health Sciences Corporation
Pfizer; Canadian Critical Care Trials Group

Completed

Dalteparin's Influence on Renally Compromised: Anti-Ten-A Study (DIRECT)

Renal Insufficiency

Canada
Canadian Critical Care Trials Group
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated... and other collaborators

Terminated

Collaborative H1N1 Adjuvant Treatment Pilot Trial (CHAT)

Critically Ill | H1N1/Influenza Infection

Canada
Canadian Retinal Trials Group
QLT Inc.; University of British Columbia; Vancouver Hospital

Unknown

Triamcinolone Acetonide as an Adjunctive to VPDT in ARMD.

Age-Related Macular Degeneration

Canada
Canadian Critical Care Trials Group
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated... and other collaborators

Terminated

Collaborative H1N1 Adjuvant Treatment (CHAT) Pilot Trial (CHAT Pilot)

H1N1 Influenza

Canada
Leiden University Medical Center
Canadian Institutes of Health Research (CIHR); AstraZeneca; National Cancer Institute... and other collaborators

Recruiting

Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features (RAINBO)

Endometrial Cancer

Netherlands, Canada, France, United Kingdom
Canadian Cancer Trials Group
National Cancer Institute (NCI); Cancer Research UK; Grupo Español de Investigación... and other collaborators

Completed

Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer | Metastatic Cancer

Canada, Spain, United States, United Kingdom
Canadian Cancer Trials Group
Cancer Research Institute, New York City; Personal Genome Diagnostics (PGDx); Mark Foundation for Cancer Research

Recruiting

Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC

Non-Small Cell Lung Cancer

Canada, United States
Hamilton Health Sciences Corporation
Canadian Institutes of Health Research (CIHR); Canadian Critical Care Trials...

Completed

PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT Pilot)

Critically Ill | Deep Venous Thrombosis

Canada, Australia
McMaster University
St. Joseph's Healthcare Hamilton; Canadian Institutes of Health Research (CIHR) and other collaborators

Active, not recruiting

CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients (CYCLE)

Respiratory Failure | Critical Care | Mechanical Ventilation | Intensive Care Unit Acquired Weakness

Canada, United States, Australia
National Cancer Institute (NCI)
NCIC Clinical Trials Group

Completed

Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Canada
Southwest Oncology Group
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

S0226 Anastrozole With or Without Fulvestrant as First-Line Therapy in Postmenopausal Women With Metastatic Breast Cancer

Breast Cancer

Canada, United States
National Cancer Institute (NCI)
Gynecologic Oncology Group; NCIC Clinical Trials Group

Terminated

Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer

Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Stage IB Cervical Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer | Cervical Adenosquamous Cell Carcinoma

United States, Canada
NCIC Clinical Trials Group
National Cancer Institute (NCI)

Completed

SB-715992 in Treating Patients With Metastatic or Recurrent Malignant Melanoma

Melanoma (Skin)

Canada
National Cancer Institute (NCI)
NCIC Clinical Trials Group

Completed

Erlotinib in Treating Patients With Locally Advanced and/or Metastatic Endometrial Cancer

Endometrial Cancer

Canada
British Columbia Cancer Agency
Canadian Urologic Oncology Group; German Testicular Cancer Study Group; NCIC...

Completed

Phase-II Study of SU011248 (Sunitinib)in Male Patients With Relapsed or Cisplatin-Refractory Germ Cell Cancer

Relapsed or Cisplatin-Refractory Germ Cell Cancer

Canada
Southwest Oncology Group
National Cancer Institute (NCI); NCIC Clinical Trials Group; Cancer and Leukemia...

Completed

S0205 Gemcitabine w/ or w/o Cetuximab as First-Line Therapy in Locally Advanced Pancreas Cancer

Pancreatic Cancer

Canada, United States
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Southwest Oncology Group; Cancer and Leukemia Group...

Completed

Sunitinib Malate or Sorafenib Tosylate in Treating Patients With Kidney Cancer That Was Removed By Surgery (ASSURE)

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage II Renal Cell Cancer AJCC v7 | Stage I Renal Cell Cancer AJCC v6 and v7

United States, Canada, Puerto Rico
University of British Columbia
Canadian Institutes of Health Research (CIHR); Genome British Columbia; Canadian...

Recruiting

Canadian COVID-19 Emergency Department Registry (CCEDRRN)

Covid-19

Canada
NCIC Clinical Trials Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Bortezomib in Treating Patients With Waldenstrom's Macroglobulinemia

Lymphoma

Canada, United States
Royal Liverpool University Hospital
NCIC Clinical Trials Group; Australasian Gastro-Intestinal Trials Group

Completed

Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer

Pancreatic Cancer

France, Australia, Canada, Sweden, Switzerland, Finland, Japan, Germany, United Kingdom, Italy, Czech Republic, Greece, Hungary
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Quality of Life in Postmenopausal Women Who Are Receiving Either Exemestane or Anastrozole With or Without Celecoxib for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

Breast Cancer

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Adjuvant Radiation Therapy Plus Hormone Therapy Compared With Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer

Prostate Cancer

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Cancer Society (CCS)

Completed

Stereotactic Body Radiotherapy Versus Conventional Radiotherapy in Medically-Inoperable Non-Small Lung Cancer Patients (LUSTRE)

Non-small Cell Lung Cancer

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Initiative

Completed

Randomized Trial of Follow-up Strategies in Breast Cancer

Breast Cancer

Canada
Ontario Clinical Oncology Group (OCOG)
Canadian Breast Cancer Foundation

Completed

Trial of Radiation Fractionation Schedules for Once-a-Day Accelerated Partial Breast Irradiation (OPAR)

Breast Cancer | DCIS

Canada
University of Manitoba
Canadian Institutes of Health Research (CIHR); Ozmosis Research Inc.; Canadian... and other collaborators

Recruiting

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia (ATTACC-CAP)

Community-acquired Pneumonia

Canada, United States, Brazil
Ontario Clinical Oncology Group (OCOG)
Canadian Cancer Society (CCS)

Completed

A Trial to Evaluate the Improvement in Lung Cancer Patients Receiving Radiation With or Without Brachytherapy (BRACHY)

Non-small Cell Lung Cancer

Canada
University of Sydney
AstraZeneca; Australasian Lung Cancer Trials Group

Active, not recruiting

Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease. (ILLUMINATE)

EGFR Mutant Advanced Non Small Cell Lung Cancer

Taiwan, Australia
Melanoma and Skin Cancer Trials Limited
University of Oxford; Trans Tasman Radiation Oncology Group

Active, not recruiting

Whole Brain Radiotherapy Following Local Treatment of Intracranial Metastases of Melanoma (WBRTMel)

Metastatic Melanoma

Norway, Australia, United Kingdom
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Southwest Oncology...

Terminated

Comparison of Two Different Doses of STI571 in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor

Gastrointestinal Stromal Tumor

United States, Canada, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Active, not recruiting

Surgery With or Without Docetaxel and Leuprolide or Goserelin in Treating Patients With High-Risk Localized Prostate Cancer

Prostate Cancer

United States, Canada
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Southwest Oncology... and other collaborators

Terminated

Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung Cancer (MARVEL)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States, Canada
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Southwest Oncology... and other collaborators

Completed

Combination Chemotherapy in Treating Patients With Stage III Colon Cancer

Stage III Colon Cancer | Adenocarcinoma of the Colon

United States
McMaster University
National Health and Medical Research Council, Australia; Canadian Institutes... and other collaborators

Completed

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial (REVISE)

Gastrointestinal Hemorrhage (Clinically Important, Upper)

Canada, Australia, United States, Brazil, Kuwait, Pakistan, Saudi Arabia, United Kingdom
McMaster University
London Health Sciences Centre; McMaster Children's Hospital; Canadian Critical...

Completed

Functional Recovery in Critically Ill Children, the Wee-Cover Multicentre Study

Pediatric Critical Illness

Canada
McMaster Children's Hospital
McMaster University; Hamilton Health Sciences Corporation; Canadian Critical...

Completed

Pilot Study for the SQUEEZE Trial (SQUEEZE)

Septic Shock

Canada
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Cancer and Leukemia... and other collaborators

Terminated

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma

Lymphoma

Canada, United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

S0000 Selenium and Vitamin E in Preventing Prostate Cancer (SELECT)

Prostate Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

SWOG-8814 Tamoxifen With or Without Combination Chemotherapy in Postmenopausal Women Who Have Undergone Surgery for Breast Cancer

Breast Cancer
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

SWOG-9416: Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage III Non-small Cell Lung Cancer

Lung Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Colorectal Cancer

United States, Canada, South Africa, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Breast Density, Hormone Levels, and Anticancer Drug Levels in Women With Invasive Breast Cancer Who Are Receiving Exemestane or Anastrozole

Breast Cancer

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer

Colorectal Cancer

United States, Canada, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite

Anorexia | Cachexia

Canada, United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Genetic Study in Patients With Stage II or Stage III Colon Cancer

Colorectal Cancer

Canada, United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast Cancer

Breast Cancer

United States, Canada, Peru
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); NCIC Clinical Trials Group

Completed

Interferon Alfa-2b With or Without Bevacizumab in Treating Patients With Advanced Renal Cell Carcinoma (Kidney Cancer)

Kidney Cancer

United States, Canada
European Organisation for Research and Treatment...
Canadian Cancer Trials Group; ECOG-ACRIN Cancer Research Group; Japan Clinical... and other collaborators

Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (STRASS2)

Leiomyosarcoma | Liposarcoma | Retroperitoneal Sarcoma

United States, Japan, France, Spain, Canada, Italy, United Kingdom, Germany, Czechia, Cyprus, Netherlands, Australia, Poland, Slovakia, Denmark

Clinical Trials Sponsored by Canadian Cancer Trials Group

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