Clinical Trials Sponsored by ICON plc

Total 11530 results

Xin Cai

Not yet recruiting

Re-irradiation Therapy of Locally Recurrent Rectal Cancer With Carbon Ion

Rectal Cancer | Recurrent

China
ICN Pharmaceuticals

Terminated

The Safety and Effectiveness of Ribavirin in the Early Stages of HIV-Infection

HIV Infections
MaxWell Clinic, PLC

Recruiting

Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19

Long COVID

United States
Gedeon Richter Plc.

Recruiting

Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome

Prader-Willi Syndrome

United States, Spain, Czechia, Italy, France
Silence Therapeutics plc

Completed

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome | Very-Low Risk Myelodysplastic Syndrome

Thailand, Israel, Jordan, United Kingdom, Germany, Italy, Malaysia
Destiny Pharma Plc

Completed

Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal Infection

Staphylococcal Infections | Surgical Site Infection

United States, Serbia, Georgia
Imperial Brands PLC

Completed

A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products

Healthy Volunteers

Sweden
Silence Therapeutics plc

Completed

A Phase 1 Study to Evaluate the Safety, Tolerability, PK and PD of SLN124 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Imperial Brands PLC

Completed

A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes

Healthy Volunteers

United Kingdom
4D pharma plc

Completed

A Trial for New Treatment of Adult Participants With Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States, United Kingdom, Ireland
Verona Pharma plc

Completed

Bronchodilator Effect of RPL554 Administered in Addition to Tiotropium/Olodaterol in Patients With COPD

COPD

United States, United Kingdom
e-Therapeutics PLC

Completed

A Phase 1 Study of Dexanabinol in Patients With Advanced Solid Tumours

Solid Tumour

United Kingdom
e-Therapeutics PLC

Completed

Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD) (ETS6103-003)

Major Depressive Disorder

United Kingdom
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
e-Therapeutics PLC

Unknown

A Study of Dexanabinol in Combination With Chemotherapy in Patients With Advanced Tumours

Hepatocellular Carcinoma | Pancreatic Cancer

Germany, Poland, Spain, United Kingdom
Destiny Pharma Plc

Completed

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

Staphylococcal Infection

United Kingdom
Verona Pharma plc

Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Chronic Obstructive Pulmonary Disorder | Inflammatory Disorder of the Respiratory Tract

United Kingdom
Gedeon Richter Plc.

Completed

A Study Aimed at Assessing the Pharmacokinetic Properties of RGB-10 and Forsteo

Healthy

United Kingdom
Gedeon Richter Plc.

Completed

A Study to Examine the, Safety, Tolerability and Pharmacokinetics Co-Administered Baclofen and Memantine in Obese and Lean, Otherwise Healthy Adults

Healthy Volunteers; | Obese, Otherwise Healthy Volunteers

United Kingdom
Imperial Brands PLC

Recruiting

Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products

Healthy Volunteers

United Kingdom
MaxWell Clinic, PLC

Recruiting

Impact of Therapeutic Plasma Exchange on RNA Biomarker Expression Levels in Alzheimer's Patients

Alzheimer Disease

United States
Silence Therapeutics plc

Recruiting

Study to Assess SLN124 in Patients With Polycythemia Vera (SLN)

Polycythemia Vera

United States, Australia, Malaysia, Bulgaria, Poland
Gedeon Richter Plc.

Recruiting

Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With Schizophrenia

Schizophrenia

Mexico, United States, Bulgaria, Colombia, Romania, Russian Federation, Serbia, Ukraine
4D pharma plc

Terminated

A Study of MRx-4DP0004 in Asthma

Asthma

United States, United Kingdom
Silence Therapeutics plc

Active, not recruiting

Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Events

Cardiovascular Diseases | Atherosclerosis | Lipoprotein(a)

Australia, Czechia, Denmark, Netherlands, Slovakia, South Africa, United Kingdom
Gedeon Richter Plc.

Completed

Comparative Efficacy and Safety Study of RGB-14-P and Prolia® in Women With Postmenopausal Osteoporosis

Postmenopausal Osteoporosis

Poland, United States, Spain, Hungary, Italy, Czechia, Bulgaria, Ukraine
Herantis Pharma Plc.

Active, not recruiting

Clinical Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema (AdeLE) (AdeLE)

Secondary Lymphedema

Finland, Sweden
4D pharma plc

Terminated

A Study of Live Biotherapeutic Product MRx0518 With Hypofractionated Radiation Therapy in Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Imperial Brands PLC

Active, not recruiting

A Relative Bioavailability Study of Nicotine Delivery From Selected Oral Nicotine Products

Healthy Volunteers

Sweden
Herantis Pharma Plc.

Terminated

A Phase I Study With Lymfactin® in the Treatment of Patients With Secondary Lymphedema

Secondary Lymphedema

Finland
Poolbeg Pharma plc

Completed

Effects of p38 MAPK Inhibitor POLB 001 on in Vivo LPS Challenge Responses

Influenza, Human

Netherlands
Silence Therapeutics plc

Withdrawn

Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome

United Kingdom, Bulgaria
Verona Pharma plc

Completed

Dose Ranging Study of RPL554 in Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD

United Kingdom, Poland, Germany, Bulgaria, Czechia, Romania
Verona Pharma plc

Completed

The Effects of RPL554 in Addition to Tiotropium in COPD Patients

Chronic Obstructive Pulmonary Disease Moderate
Imperial Brands PLC

Completed

A Study to Evaluate the Safety Profile of an e-Vapour Product

Healthy Volunteers

United Kingdom
Destiny Pharma Plc

Completed

Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects

Staphylococcus Aureus Infection

United Kingdom
Verona Pharma plc

Completed

Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients

Asthma

Sweden, United Kingdom
Redx Pharma Plc

Completed

A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

Colorectal Cancer

Spain, Korea, Republic of, United Kingdom, United States
Redx Pharma Plc

Active, not recruiting

Study to Evaluate the Safety and Tolerability of RXC004 in Advanced Malignancies

Cancer | Solid Tumor

United Kingdom
4D pharma plc

Withdrawn

Study of MRx0518 and Avelumab in Patients With Urothelial Carcinoma (AVENU)

Urothelial Carcinoma

United States
Nanoform Finland Plc

Completed

PK Evaluation of a Nanoformed Oral IR Piroxicam Tablet in Healthy Subjects

Pain

United Kingdom
4D pharma plc

Withdrawn

A Study for Efficacy and Safety of Live Biotherapeutic MRx4DP0004 to Treat COVID-19

COVID-19

United Kingdom
4D pharma plc

Completed

Study of Bacteroides Thetaiotaomicron in Young People Aged 16 to 18 Years With Stable Crohn's Disease

Crohn's Disease

United Kingdom
Gedeon Richter Plc.

Completed

Study to Compare the Pharmacokinetics and Pharmacodynamics of 6 mg RGB-02 to 6 mg Neulasta

Bioequivalence

United Kingdom
Verona Pharma plc

Completed

The Effects of RPL554 on Top of Standard COPD Reliever Medications

Chronic Obstructive Pulmonary Disease

United Kingdom
Imperial Brands PLC

Completed

A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product

Healthy Volunteers

United Kingdom
Gedeon Richter Plc.

Completed

Cariprazine: Comparison of Slow- and Immediate-release Forms

Pharmacokinetic Profile

United Kingdom
Gedeon Richter Plc.

Unknown

Comparative Pharmacokinetic Trial of RGB-03 and MabThera

Rheumatoid Arthritis
University Hospital, Antwerp
Karolinska Institutet; Erasmus Medical Center; University of California, San... and other collaborators

Completed

CENTER-TBI: Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Traumatic Brain Injury

Germany, Norway, United Kingdom, Belgium, Netherlands, Denmark, Finland, Sweden, France, Switzerland, Israel, Spain, Austria, Serbia, Latvia, Hungary, Italy, Lithuania, Romania
Carleton University
Hopital Montfort; University of Ottawa; Lucky Iron Fish Enterprise

Recruiting

Assessing the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age

Iron Deficiency | Iron Deficiency Anaemia

Canada

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