Clinical Trials Sponsored by Royal Papworth Hospital NHS Foundation Trust

Total 2513 results

Royal Brompton & Harefield NHS Foundation Trust

Completed

Role of Routine on-Table Cholangiography in Laparoscopic Cholecystectomy

Common Bile Duct Stones

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Portsmouth... and other collaborators

Unknown

The Wessex Fit-4-Cancer Surgery Trial (WesFit)

Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Trans-coronary Cooling and Dilution for Cardioprotection During Revascularisation for ST-elevation Myocardial Infarction (STEMI-Cool)

Myocardial Infarction | Reperfusion Injury, Myocardial

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Multisystem and Autonomic Complications of NMD on Long-term NIV

Neuromuscular Diseases | Neurologic Disorder

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

The Prognostic Significance of Fibrosis Detection in Cardiomyopathy

Coronary Artery Disease | Cardiomyopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Active, not recruiting

Cardiac Cachexia in Advanced Heart Failure (CACH-IT-AHF)

Weight Loss | Advanced Heart Failure | Cardiac Cachexia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

DIGITAL-HF - Digital Tools in Heart Failure - a Survey of Patient Usage (DIGITAL-HF) (DIGITAL-HF)

Heart Failure

United Kingdom
Royal Marsden NHS Foundation Trust
Bayer

Completed

Prospective Translational Study Investigating Molecular Predictors of Resistance and Response to Regorafenib Monotherapy (PROSPECT-R)

Metastatic Colorectal Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension (PH)

Pulmonary Hypertension

United Kingdom
Royal Marsden NHS Foundation Trust
AstraZeneca

Unknown

A Translational Study of Single Agent Olaparib in the Treatment of Advanced Oesophagogastric Cancer (SOLAR)

Gastric Cancer | Oesophageal Cancer | Gastro-Oesophageal Junction Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Valves (BLOOD-VALVES)

Chronic Obstructive Pulmonary Disease | Emphysema

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis

Gastroesophageal Reflux | Systemic Sclerosis | Interstitial Lung Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Terminated

A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics (SARAH)

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Renal Denervation in Heart Failure With Preserved Ejection Fraction (RDT-PEF)

Cardiac Failure

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis?

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

A Comparison of Advanced Imaging Techniques in Aortic Stenosis (AIm-AS)

Aortic Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Comparing Laboratory Blood Glucose Results With HemoCue Glucose 201 RT (CFRD)

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

LV Endocardial Cardiac Resynchronisation Therapy (ENDO-CRT)

Heart Failure

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Catheter Ablation Versus Medical Rate Control for Atrial Fibrillation in Patients With Heart Failure (ARC-HF)

Heart Failure | Atrial Fibrillation

United Kingdom
AstraZeneca
Royal Marsden NHS Foundation Trust

Completed

DCE CT/MRI Scanning Study in Patients With Solid Tumours (AstraZeneca and Royal Marsden Hospital Imaging Study)

Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Renal Function in Adults With Congenital Heart Disease.

Cardiovascular Abnormalities | Kidney Failure

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Oral Allergy Syndrome (OAS): a Pilot Study to Evaluate a Clinical Questionnaire as a Diagnostic Tool

Rhinitis | Food Allergy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation

Lung Diseases | Bronchiectasis | Emphysema | Cystic Fibrosis | Alveolitis, Fibrosing

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Specialist Dietetic Intervention in Malnourished Patients With Fibrotic ILD: a Randomised Controlled Pilot Trial (DT-ILD)

Interstitial Lung Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

HDM and Silver Birch NAC Standardisation

Allergic Rhinitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Individualised Mapping in Persistent AF Ablation (IMAGE AF)

Persistent Atrial Fibrillation
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders (CLASSIC)

Neuromuscular Diseases | Neurological Diseases or Conditions

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

The Harefield Acute Myocardial Infarction Cohort (HEART - ACS)

Acute Coronary Syndrome

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (COPD-ENVIRON)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone

Cardiomyopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Patients (EAT-PK)

Critical Illness | Infection | Extracorporeal Membrane Oxygenation Complication

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

EBUS-TBNA vs Acquire TBNB

Mediastinal Lymphadenopathy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Evaluation of Speckle Tracking Parameters as Predictors of Successful VA SPECKLE ECMO (SPECKLE-ECMO)

Cardiogenic Shock

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement? (RECOVER-TAVR)

Aortic Stenosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Terminated

Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery

Blood Coagulation Disorders | Blood Platelet Disorders | Cardiopulmonary Bypass | Cardiac Surgical Procedures

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and Feasibility Study (LEIO-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Marsden NHS Foundation Trust
AstraZeneca

Unknown

Proof-of-Concept Study of AZD4547 in Patients With FGFR1 or FGFR2 Amplified Tumours (FGFR)

Breast Cancer | Gastric Cancer | Squamous Cell Carcinoma of the Lung | Oesophageal Cancer

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Withdrawn

Dysfunctional Breathing in Difficult Asthma.

Asthma

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients

Myocardial Infarction

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis? (ACT)

Cystic Fibrosis
Royal Brompton & Harefield NHS Foundation Trust

Completed

Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis?

Cystic Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire

Food Allergy

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Airway Clearance Using High Frequency Chest Wall Oscillation

Cystic Fibrosis

United Kingdom
Papworth Hospital NHS Foundation Trust
King's College London; University Hospitals, Leicester

Recruiting

Nasal Oxygen Therapy After Cardiac Surgery (NOTACS)

Coronary Artery Disease | Respiratory Failure | Cardiac Valve Disease

United Kingdom
Oxford University Hospitals NHS Trust
Northampton General Hospital NHS Trust; University Hospital of Wales; Royal Berkshire... and other collaborators

Terminated

Observational Study of the LMA Protector (ADEPT1)

Airway Complication of Anesthesia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Oxford University Hospitals NHS Trust; Sherwood Forest Hospitals NHS Foundation...

Unknown

Ballooned Intercostal Drain Trial

Pneumothorax | Pleural Effusion

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Imperial College London and other collaborators

Active, not recruiting

Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spirometry Datasets - a Retrospective Analysis

Respiratory Disease

United Kingdom
Royal Marsden NHS Foundation Trust
Imperial College Healthcare NHS Trust

Completed

Primary Radiotherapy And DIEP flAp Reconstruction Trial (PRADA)

Breast Cancer

United Kingdom

Clinical Trials Sponsored by Royal Papworth Hospital NHS Foundation Trust

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