Clinical Trials Sponsored by University of Southampton

Total 109311 results

Africa Health Research Institute
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Recruiting

Home-based Intervention to Test and Start (HITS)

HIV | HIV Testing | Linkage to Care

South Africa
Michelle Mossa
University Hospital Southampton NHS Foundation Trust

Completed

Exercise Training in Colorectal Cancer Patients

Rectal Cancer

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Free and University College Medical School

Completed

Targeted Radiotherapy in HSCT for Poor Risk Haematological Malignancy

Lymphoma | Myeloma | Acute Leukaemia | Chronic Leukaemia

United Kingdom
Imperial College London
University of Nottingham; University College, London; University of Southampton; Queen's University, Belfast and other collaborators

Active, not recruiting

The BLF Early COPD Development Partnership Grant

Chronic Obstructive Pulmonary Disease

United Kingdom
Acurable Ltd.
University Hospital Southampton NHS Foundation Trust; Sheffield Children's...

Recruiting

Clinical Evaluation of a Paediatric Sleep Diagnosis Technology

Sleep Apnea

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

A Feasibility Study of Early Mobilisation Programmes in Critical Care (EMPRESS)

Critical Illness

United Kingdom
Oxford University Hospitals NHS Trust
University Hospital Southampton NHS Foundation Trust; University Hospital Birmingham

Completed

Diagnostic Accuracy of WEARable TECHnology Single-lead ECG in Detecting Cardiac Arrhythmias (WEAR-TECH ECG)

Atrial Fibrillation | Cardiac Arrhythmia

United Kingdom
NHS Greater Glasgow and Clyde
University of Southampton; NHS Lanarkshire; National Heatlh Service Ayrshire...

Unknown

Enhancing Fitness With Preoperative Exercise in Colorectal Cancer Surgery (EFEx)

Colorectal Cancer

United Kingdom
St George's, University of London
University Hospital Southampton NHS Foundation Trust; St George's University...

Recruiting

Eosinophilic Oesophagitis Assessment With String Testing (EoEAST)

Eosinophilic Esophagitis

United Kingdom
University Hospital Southampton NHS Foundation...
University College, London; Bill and Melinda Gates Foundation

Completed

A Clinical Trial of Nebulized Surfactant for the Treatment of Moderate to Severe COVID-19 (COVSurf)

Respiratory Infections

United Kingdom
University of Southampton
National University Hospital, Singapore; Singapore Institute for Clinical Sciences and other collaborators

Completed

Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health (NiPPeR)

Hyperglycemia

Singapore, United Kingdom, New Zealand
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE) (VALUE)

Oesophageal Cancer

United Kingdom
Imperial College London
University Hospital Southampton NHS Foundation Trust; Oxford University Hospitals...

Completed

Understanding Childhood Infection, Inflammation and Allergy

Inflammation | Allergy | Children | Infection

United Kingdom
University Hospital Southampton NHS Foundation...
Liverpool Heart and Chest Hospital NHS Foundation Trust

Unknown

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes? (RIPCORD 2)

Chest Pain | Acute Coronary Syndrome | Stable Angina | Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
Queen's University, Belfast
Mayo Clinic; University Hospital Southampton NHS Foundation Trust; University... and other collaborators

Completed

Myeloproliferative Neoplasms: an In-depth Case-control Study (MOSAICC)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Eye Movement Desensitisation and Reprocessing (EMDR) to Improve Mental Health Following Intensive Care Admission (EMERALD)

Critical Illness | Post Traumatic Stress Disorder | Depression, Anxiety | Eye Movement Desensitisation and Reprocessing

United Kingdom
University Hospital Southampton NHS Foundation...
South Central Ambulance Service NHS Foundation Trust

Completed

Do Patients Suffering a Cardiac Arrest Present to the Ambulance Service With Symptoms in the Preceeding 48hrs?

Cardiac Arrest

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Investigation of Synbiotic Treatment in NAFLD (INSYTE)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Treatment of Non Alcoholic Fatty Liver Disease With n-3 Fatty Acids (WELCOME)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Grip Strength Routine Implementation (GRImP)

Frail Elderly, Inpatients

United Kingdom
University of Dundee
University of Southampton; Newcastle University; University of Aberdeen; Chief... and other collaborators

Completed

Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care (WIME)

Antibiotic Prescribing by GPs for URTI

United Kingdom
University of Hertfordshire
University of Southampton; University of Plymouth; Imperial College Healthcare... and other collaborators

Recruiting

A Study to Evaluate the Introduction of New Staffing Models in Intensive Care: a Realist Evaluation (SEISMIC-R) (SEISMIC-R)

Critical Illness | Intensive Care | Staff Attitude | Organisation

United Kingdom
University of Southampton
Imperial College London; University of Manchester; Royal Berkshire NHS Foundation... and other collaborators

Completed

Optimisation of Hearing Aid Fitting

Hearing Loss | Hearing Abnormality

United Kingdom
University Hospital Southampton NHS Foundation...
Cancer Research UK; IntraOp Medical Corporation; PLANETS Cancer Charity

Active, not recruiting

Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial (ELECTRA)

Locally Advanced Rectal Cancer | Locally Recurrent Rectal Cancer

United Kingdom
Imperial College London
University of Nottingham; University College, London; University of Sheffield; Medical... and other collaborators

Recruiting

The UK Interstitial Lung Disease Long-COVID19 Study (UKILD-Long COVID): Understanding the Burden of Interstitial Lung Disease in Long COVID. (UKILD)

Interstitial Lung Disease | SARS-CoV-2 Infection

United Kingdom
University Hospital Southampton NHS Foundation...
Bristol-Myers Squibb; Cancer Research UK; Institute of Cancer Research, United...

Completed

The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer (ICE)

Extensive Stage Small Cell Lung Cancer

United Kingdom
University of California, San Francisco
London School of Hygiene and Tropical Medicine; University of Southampton; University... and other collaborators

Completed

Evaluation of Reactive Focal Mass Drug Administration (rfMDA) +/- Reactive Focal Vector Control (RAVC) in Namibia

Malaria

Namibia
University Hospital Southampton NHS Foundation...
Macmillan Cancer Support; CanRehab Trust; Wessex Cancer Alliance

Active, not recruiting

SafeFit Trial: Virtual Clinics to Deliver Universal Interventions in People With Cancer

Cancer | COVID

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

Unknown

Exercise Intervention During Chemotherapy in Advanced Lung Cancer Patients (EMBRACE)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | Non Small Cell Lung Cancer Metastatic

United Kingdom
University Hospital Southampton NHS Foundation...
University of Aberdeen; Association of Paediatric Anaesthetists of Great Britain... and other collaborators

Unknown

PErioperAtive CHildhood ObesitY (PEACHY)

Pediatric Obesity | Obesity, Childhood | Overweight and Obesity | Perioperative/Postoperative Complications
Imperial College London
King's College Hospital NHS Trust; University of Oxford; University of Southampton and other collaborators

Unknown

Evaluating Liraglutide in Alzheimer's Disease (ELAD)

Alzheimer's Disease

United Kingdom
Imperial College London
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Unknown

EndoBarrier TM Gastrointestinal Liner Diabetes Trial (EndoBarrier)

Diabetes | Overweight and Obesity

United Kingdom
NHS Greater Glasgow and Clyde
Merck Sharp & Dohme LLC; Cancer Research UK; University of Southampton; Queen's... and other collaborators

Unknown

Study of FAK (Defactinib) and PD-1 (Pembrolizumab) Inhibition in Advanced Solid Malignancies (FAK-PD1)

Pancreatic Neoplasms | Mesothelioma | Carcinoma, Non-small-cell Lung

United Kingdom
Pier Lambiase
University Hospital Southampton NHS Foundation Trust; The Royal Bournemouth...

Completed

Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation

Atrial Fibrillation

United Kingdom
Boston Children's Hospital
Emory University; Imperial College London; University of Southampton; University... and other collaborators

Not yet recruiting

Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy (PAPA)

Asthma | Allergy
University of Birmingham
King's College Hospital NHS Trust; University Hospital Southampton NHS Foundation... and other collaborators

Not yet recruiting

Paediatric Early Rehabilitation & Mobilisation During InTensive Care (PERMIT) Feasibility (PERMIT)

Critical Illness | ICU

United Kingdom
University of Southampton
University of Nottingham; Nottingham University Hospitals NHS Trust; East Kent... and other collaborators

Recruiting

Aspirin to Target Arterial Events in Chronic Kidney Disease (ATTACK)

Cardiovascular Diseases | Chronic Kidney Diseases | Bleeding

United Kingdom
University of Southampton
National University Hospital, Singapore; Singapore Institute for Clinical Sciences and other collaborators

Enrolling by invitation

NiPPeR Randomised Trial - Child Follow Up Study (NiPPeR Child)

Neurobehavioral Manifestations | Allergy | Microbial Colonization | Growth Disorders | Atopic Dermatitis | Obesity, Childhood | Metabolic Disturbance | Cognition | Lifestyle | Breastfeeding | Nutrition, Healthy | Atopy

Singapore, United Kingdom, New Zealand
University of Nottingham
AbbVie; University of Southampton; University of Bristol; University of Birmingham and other collaborators

Active, not recruiting

National Unified Renal Translation Research Enterprise - Chronic Kidney Disease (NURTuRE-CKD)

Chronic Kidney Diseases

United Kingdom
University Hospital Southampton NHS Foundation...
Medical Research Council; National Institute for Health Research, United Kingdom

Completed

The Southampton Mealtime Assistance Roll-out Trial (SMART)

Volunteer Mealtime Assistants

United Kingdom
Nottingham University Hospitals NHS Trust
University of Nottingham; University of Southampton; University of East Anglia; University of Liverpool and other collaborators

Unknown

Designing a Trial of Bilateral Cochlear Implantation in Adults (FOUNDATION)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral

United Kingdom
University College Cork
University of Southampton; Carol Davila University of Medicine and Pharmacy; Engineering... and other collaborators

Not yet recruiting

Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism (ENIGMA-I)

Autism Spectrum Disorder | Autism

Ireland, United Kingdom, Romania
Children's Health Ireland
Belfast Health and Social Care Trust; University of Edinburgh; University Hospital... and other collaborators

Recruiting

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome (REFRESHED)

Quality of Life | Obstructive Sleep Apnea | Down Syndrome | Behavior | Adherence, Treatment

United Kingdom, Ireland
Zealand University Hospital
Danish Cancer Society; University Hospital Southampton NHS Foundation Trust; Region... and other collaborators

Active, not recruiting

Pre-operative Exercise During Neoadjuvant Chemotherapy in Patients With Breast Cancer (Neo-train)

Breast Cancer

Denmark
University Hospital Southampton NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS...

Unknown

VEST: The UK Vedolizumab Real Life Experience Study in Inflammatory Bowel Disease (VEST)

Crohn's Disease | Ulcerative Colitis

United Kingdom
University of Oxford
King's College London; University of Southampton; Barts & The London NHS Trust; University of Birmingham and other collaborators

Completed

Blood Pressure Monitoring in High Risk Pregnancy to Improve the Detection and Monitoring of Hypertension (BUMP)

Hypertension | Pregnancy, High Risk | Pre-Eclampsia | Hypertension, Pregnancy-Induced

United Kingdom
University of Southampton
National Institute for Health Research, United Kingdom; Collaboration for Leadership...

Completed

Clinical And Social Characteristics and Demographics in COPD (CASCADE)

Chronic Obstructive Pulmonary Disease

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College London; University of Bristol; University Hospitals Bristol... and other collaborators

Completed

Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study (StePS)

Sepsis

United Kingdom
University Hospital Southampton NHS Foundation...
Boston Scientific Corporation; Liverpool Heart and Chest Hospital NHS Foundation...

Completed

Boston Scientific COMET Wire Validation Study (COMET)

Stable Angina

United Kingdom
University College, London
University Hospital Southampton NHS Foundation Trust; Bangor University; St George... and other collaborators

Active, not recruiting

Cognitive Rehabilitation for People With Cognitive Covid19

Long Covid19

United Kingdom

Clinical Trials Sponsored by University of Southampton

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