Search clinical trials for: CNT

Total 439 results

Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Isabelle Fortin
Janssen Inc.

Completed

Assessment of Tender & Swollen Joints Count Score Performed by a Rheumatologist And Rheumatology Nurses in Patients With RA and PsA. (APRAN)

Rheumatoid Arthritis | Psoriatic Arthritis

Canada
Janssen Pharmaceutical K.K.

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Guselkumab Following a Single Intravenous Administration in Healthy Japanese Participants

Healthy

Japan
Washington University School of Medicine

Completed

Exome Sequencing for Atypical Femoral Fractures

Osteoporosis | Atypical Femoral Fractures | Bisphosphonate Therapy
Centrexion Therapeutics

Completed

A Placebo-Controlled, Two-Part Study, Oral Dose to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of CNTX-6970 in Healthy Subjects

Chronic Pain | Nociceptive Pain

United States
Centrexion Therapeutics

Completed

The Effect of Injection Site Cooling on Pain Experienced After the Administration of CNTX-4975-05 Into the Knee

Osteoarthritis, Knee

United Kingdom
Centrexion Therapeutics

Completed

A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis

Knee Osteoarthritis

United States
US Oncology Research
Pfizer

Completed

Phase II Sunitinib Prog Met AIPC

Metastatic Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis

Psoriasis

United States, Canada, Poland
Merrimack Pharmaceuticals

Completed

A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer (CARRIE)

Pancreatic Cancer

United States, Canada, Spain, Poland, United Kingdom, Germany
Neurotech Pharmaceuticals
The Emmes Company, LLC; The Lowy Medical Research Institute Limited

Completed

A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel

Macular Telangiectasia Type 2

United States, Australia
Boehringer Ingelheim

Completed

Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)

Atrial Fibrillation | Percutaneous Coronary Intervention

Canada, United States, Spain, Korea, Republic of, Australia, Germany, Taiwan, Hong Kong, Thailand, United Kingdom, Turkey, Netherlands, Ireland, Hungary, Croatia, Colombia, Israel, Singapore, Italy, New Zealand, Greece, Mexico, Norway, Swed... and more
Seres Therapeutics, Inc.
Syneos Health

Completed

SER-109 Versus Placebo to Prevent Recurrent Clostridium Difficile Infection (RCDI) (ECOSPOR)

Clostridium Difficile

United States
Eli Lilly and Company
AstraZeneca

Withdrawn

A Study of LY3314814 in Participants With Liver Impairment

Hepatic Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety of Long-term Treatment With Siltuximab in Patients With Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Israel, Korea, Republic of, Singapore, Brazil, Belgium, New Zealand, Norway, Egypt, Hong Kong
Centrexion Therapeutics

Completed

A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)

Morton's Neuroma

United States
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)

Arthritis, Rheumatoid

United States, France, Poland, United Kingdom, Germany, Taiwan, Spain, Mexico, Portugal, Korea, Republic of, Japan, Canada, New Zealand, Russian Federation, Puerto Rico, Austria, Argentina, Lithuania, Belgium, Croatia, Australia, ...
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Belgium, Israel, India, Korea, Republic of, Netherlands, Singapore, Brazil, Russian Federation, New Zealand, Hungary, Norway, Australia, Egypt, Hong Kong, Malaysi...
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Known Breast Lesions

Breast Neoplasms

United States
Edge Therapeutics Inc

Completed

Safety and Tolerability Study of EG-1962 in Aneurysmal Subarachnoid Hemorrhage (NEWTON)

Ruptured Cerebral Aneurysm | Ruptured Berry Aneurysm

United States, Canada, Czechia, Finland
Centocor, Inc.

Completed

A Study of Effectiveness and Safety of CNTO 136 in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Arthritis, Rheumatoid

Poland, United States, Mexico, Korea, Republic of, Japan, Russian Federation, Hungary
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Taiwan, Mexico, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Lithuania, Colombia, Croatia
Janssen Research & Development, LLC

Completed

A Study of Golimumab in Participants With Active Ankylosing Spondylitis

Ankylosing Spondylitis

United States, Poland, Ukraine, Germany, Korea, Republic of, Russian Federation, Australia, Mexico, Canada
Janssen Pharmaceutical K.K.

Withdrawn

Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)

Macular Degeneration | Geographic Atrophy | Visual Acuity

Japan
Janssen Research & Development, LLC

Completed

A Study of Golimumab in Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic

Poland, Ukraine, United States, Germany, Belarus, Spain, Romania, Russian Federation, Hungary, Lithuania, Australia, Canada
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis (SIRROUND-H)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Germany, Spain, Colombia, Mexico, Bulgaria, Romania, Serbia, South Africa, Chile, Russian Federation, Hungary, Lithuania, Moldova, Republic of
Ananias Diokno
National Institute on Aging (NIA)

Completed

Group Learning Achieves Decreased Incidents of Lower Urinary Symptoms (Gladiolus)

Urinary Incontinence, Stress | Urinary Incontinence, Urge

United States
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Psoriasis

United States
Hoffmann-La Roche

Completed

A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)

Non-Squamous Non-Small Cell Lung Cancer

United States, France, Austria, Denmark, Italy, Spain, Germany, Mexico, Netherlands, Japan, Brazil, Greece, Argentina, Slovakia, Lebanon, Belgium, Oman, United Arab Emirates
Janssen Research & Development, LLC

Completed

A Study of Guselkumab in Participants With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab (NAVIGATE)

Psoriasis

United States, Poland, United Kingdom, Germany, Taiwan, Spain, Australia, Canada, Korea, Republic of, Russian Federation
Centocor, Inc.

Completed

A Study of the Safety and How the Body Affects a Drug (CNTO 1959) in Healthy Volunteers and in Patients With Psoriasis

Psoriasis

United States
Janssen Pharmaceutical K.K.

Completed

A Study of the Safety, Tolerability, Pharmacokinetics (What the Body Does to the Drug), and Pharmacodynamics (What the Drug Does to the Body) of CNTO 1959 Following a Single Subcutaneous (Under the Skin) Administration in Japanese Participants With Moderate to Severe Plaque Psoriasis

Psoriasis

Japan
Population Council
Bill and Melinda Gates Foundation; Centers for Disease Control and Prevention; Ministry of Health, Thailand and other collaborators

Completed

Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide

HIV Infections | Herpes Simplex | Syphilis | Trichomonas Vaginitis | Chlamydia Trachomatis | Neisseria Gonorrhoeae

Thailand
Centrexion Therapeutics

Completed

Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain

Osteoarthritis

United States
Janssen Research & Development, LLC

Completed

A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration

Age-related Macular Degeneration

United States
Janssen Inc.

Completed

A Study to Evaluate CNTO 1959 in the Treatment of Patients With Moderate to Severe Plaque-type Psoriasis (X-PLORE)

Psoriasis

United States, Poland, Canada, Belgium, Germany
BG Unfallklinik

Unknown

Chitosan Nerv Tube for Primary Repair of Traumatic Sensory Nerve Lesions of the Hand (CNT)

Traumatic Lesion of Sensory Nerves of the Hand

Germany
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of MABT5102A in Patients With Mild to Moderate Alzheimer's Disease (ABBY)

Alzheimer's Disease

United States, Spain, France, Canada, Germany, United Kingdom
AstraZeneca

Completed

Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes

Type 2 Diabetes

Korea, Republic of, Mexico, South Africa, United States, Canada, Puerto Rico, Poland, Romania
Janssen Biotech, Inc.

Terminated

A Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADE®) (REGAIN)

Arthritis, Rheumatoid

United States, Canada
Janssen Pharmaceutical K.K.

Completed

A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.

Colitis, Ulcerative

Japan
Janssen Pharmaceutica

Completed

A Study to Assess the Severity of Psoriasis in Brazilians Participants With Chronic Plaque-type Psoriasis

Psoriasis | Plaque

Brazil
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Janssen-Cilag, S.A.

Terminated

Registry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumab (Go-Compl-Ar)

Rheumatoid Arthritis

Colombia
Janssen Biotech, Inc.

Completed

A Study of Ustekinumab to Evaluate a "Subject-tailored" Maintenance Dosing Approach in Subjects With Moderate-to-Severe Plaque Psoriasis (PSTELLAR)

Psoriasis

United States
National Institute on Drug Abuse (NIDA)

Completed

Integrated Treatment for Cocaine and Mood Disorders - 1

Depressive Disorder, Major | Cocaine Dependence

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction Therapy in Patients With Moderately to Severely Active Crohn's Disease (UNITI-2)

Crohn's Disease | Colitis | Inflammatory Bowel Disease | IBD

United States, France, Poland, United Kingdom, Germany, Spain, Israel, Bulgaria, Serbia, South Africa, Japan, Australia, Canada, Netherlands, Korea, Republic of, New Zealand, Brazil, Russian Federation, Belgium, Hungary, Croatia, ...
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative

France, Ukraine, United States, Poland, Bulgaria, Canada, Netherlands, Belgium, Russian Federation, Germany, Hungary, Czech Republic
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety and Efficacy of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease Who Have Failed or Are Intolerant to Tumor Necrosis Factor (TNF) Antagonist Therapy (UNITI-1)

Crohn's Disease | Colitis | Inflammatory Bowel Disease | IBD

United States, France, Poland, United Kingdom, Germany, Spain, Serbia, South Africa, Japan, Israel, Canada, Australia, Netherlands, Korea, Republic of, Belgium, New Zealand, Brazil, Austria, Ireland, Czech Republic, Hungary, Denmark, Icela...
Centrexion Therapeutics

Completed

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Osteoarthritis of the Knee

United States

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