Search clinical trials for: Dopamine Agonist

Total 17515 results

Axsome Therapeutics, Inc.

Completed

Open-Label Safety Study of AXS-05 in Subjects With Depression

Depression | Major Depressive Disorder | Treatment Resistant Depression

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)

Borderline Personality Disorder

United States
Population Health Research Institute

Completed

DIalysis Symptom COntrol-Restless Legs Syndrome Trial (DISCO-RLS)

Restless Legs Syndrome | End Stage Renal Disease

Canada
Medical College of Wisconsin

Terminated

Fenoldopam to Prevent Renal Dysfunction in Indomethacin Treated Preterm Infants (Fenaki)

Acute Kidney Injury (AKI) | Patent Ductus Arteriosus (PDA)

United States
Denovo Biopharma LLC

Completed

A Study of Safety and Tolerability in Subjects With Schizophrenia

Schizophrenia

United States
Shanghai Mental Health Center

Withdrawn

Acceptance and Commitment Therapy in SSRI-Resistant Obsessive Compulsive Disorder

Obsessive-Compulsive Disorder
Future University in Egypt

Completed

Bioequivalence Study of Aripiprazole in Healthy Adult Subjects Under Fasting Condition

Healthy Subjects

Egypt
Denovo Biopharma LLC

Terminated

A Comparison Study of LY2140023 and Aripiprazole in Schizophrenia Patients

Schizophrenia

Germany, Spain, United States, Belgium, France, Sweden, Austria, Poland, Puerto Rico, Romania
University of North Carolina, Chapel Hill
American Diabetes Association

Completed

Examination of Bromocriptine on Homeostatic and Hedonic Mechanisms of Food Intake in Individuals at High Risk for T2DM

Overweight and Obesity | Eating Behavior

United States
King's College London
Shire

Active, not recruiting

Experimental fMRI Study of Guanfacine and Lisdexamfetamine in ADHD Adolescents (AGUALIS)

ADHD

United Kingdom
University Hospital Freiburg

Withdrawn

Aripiprazole Augmentation Therapy in Treatment-resistant Depression

Therapy-resistant Depression

Germany
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study of Brexpiprazole in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
University of Alberta

Terminated

Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD

Restless Legs Syndrome | End Stage Renal Disease

Canada
Washington University School of Medicine

Completed

Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis (ALS and PLS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

United States
I.R.C.C.S. Fondazione Santa Lucia
Alzheimer's Drug Discovery Foundation

Active, not recruiting

Dopaminergic Therapy for Frontotemporal Dementia Patients

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurologic Manifestations | Neurobehavioral Manifestations | Neurocognitive Disorders | Neurodegenerative Diseases | TDP-43 Proteinopathies | Proteostasis Deficiencies | Dementia | Language Disorders | Communication... and other conditions

Italy
University Hospitals Cleveland Medical Center

Terminated

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

Hypoxia

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial of Brexpiprazole in the Treatment of Borderline Personality Disorder

Borderline Personality Disorder

United States, Spain, Ukraine
Shanghai Mental Health Center

Completed

a Pilot Study of Pramipexole to Treat Extrapyramidal Symptoms Induced by Antipsychotics

Extrapyramidal Syndrome

China
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States, Canada
Impax Laboratories, LLC

Completed

A Study to Assess the PK and Pharmacodynamics of IPX203 in Subjects With Advanced Parkinson's Disease

Advanced Parkinson's Disease

United States
University Hospital, Grenoble

Completed

Impact of Early Optimization of Brain Oxygenation on Neurological Outcome After Severe Traumatic Brain Injury (OXY-TC)

Brain Injuries, Traumatic

France
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess the Safety and Efficacy of ASP4345 as Add-on Treatment for Cognitive Impairment in Subjects With Schizophrenia on Stable Doses of Antipsychotic Medication

Schizophrenia

United States
Knopp Biosciences
Biogen

Terminated

Phase 3 Extension Study of Dexpramipexole in ALS (ENVISION)

Amyotrophic Lateral Sclerosis

United States, United Kingdom, Netherlands, Spain, Belgium, Germany, Australia, Sweden, France, Ireland, Canada
University of New Mexico
University of New Mexico Clinical and Translational Science Center

Completed

Non-Opioid Pramipexole and Pain

Chronic Pain

United States
Otsuka Pharmaceutical Co., Ltd.

Withdrawn

A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With Schizophrenia

Schizophrenia
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Completed

Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD (ASCERTAINTRD)

Treatment Resistant Major Depressive Disorder

United States, Canada
Satsuma Pharmaceuticals, Inc.

Completed

A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects

Migraine | Migraine Without Aura | Migraine With Aura

United States
Kyoto University
Osaka University; Mie University; Tokushima University; Tokyo Metropolitan Geriatric... and other collaborators

Completed

Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease (REBRAnD)

Familial Alzheimer Disease (FAD) | PSEN1 Mutation

Japan
Korea Otsuka International Asia Arab

Completed

ABLE: Abilify in Bipolar Disorder for Long-term Effectiveness (ABLE)

Bipolar Disorder

Philippines, Hong Kong, Taiwan, Thailand
University of Chicago
Otsuka America Pharmaceutical

Completed

Brexpiprazole in Borderline Personality Disorder

Borderline Personality Disorder

United States
Thomas Jefferson University

Completed

A Research Study Examining Migranal and Skin Sensitivity in Subjects With Migraine

Migraine

United States
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Ontario

Completed

Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease

Cerebrovascular Disorders | Smoking Cessation

Canada
Martha Sajatovic
Otsuka Pharmaceutical Development & Commercialization, Inc.

Completed

CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)

Bipolar Disorder | Medication Adherence | Medication Non Adherence

United States
New York State Psychiatric Institute
National Institute of Mental Health (NIMH); Columbia University

Suspended

Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing

Depressive Disorder

United States
University of Liege
Université Catholique de Louvain

Active, not recruiting

Treating Severe Brain-injured Patients With Apomorphine

Disorder of Consciousness

Belgium
Organon and Co

Completed

An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308)

Bipolar Disorder
University of Medicine and Dentistry of New Jersey

Completed

Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children (Abilify)

Autism

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole for the Long-term Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type

Agitation Associated With Dementia of the Alzheimer's Type

Japan
Sunovion

Completed

A Study of an Investigational Drug to See How it Affects the People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes) Compared to an Approved Drug Used to Treat People With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes)

Motor OFF Episodes Associated With Parkinson's Disease

Spain, United Kingdom, Germany, Italy, Austria, France
VA Office of Research and Development

Completed

Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers

Tobacco Use Disorder | Homelessness

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

United States, Spain, Hungary, South Africa, Croatia, France, Poland, India, Canada, Sweden, Malaysia
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

MAintain the Efficacy and Safety in Treatment of Schizophrenia After Switching to Long-acTing Injectable aRipiprazole From Oral Atypical Antipsychotics (MAESTRO)

Schizophrenia | Antipsychotics | Long-Acting Injection | LAI | Aripiprazole

Korea, Republic of
New York State Psychiatric Institute
Columbia University; Shire; American Academy of Child Adolescent Psychiatry.

Completed

An fMRI Study of Stimulant vs. Non-Stimulant Treatment of ADHD

Attention Deficit Hyperactivity Disorder

United States
Eastern Virginia Medical School

Completed

Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects

Diabetic Autonomic Neuropathy

United States
Dong Jie

Terminated

Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients

Restless Legs Syndrome

China
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

Stress Disorders, Post-Traumatic

United States
M.D. Anderson Cancer Center
National Institute on Drug Abuse (NIDA); Pfizer; National Institutes of Health...

Completed

Combining Varenicline and Bupropion for Smoking Cessation

Smoking Cessation

United States
Janssen Scientific Affairs, LLC

Completed

A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform (DREaM)

Psychotic Disorders | Schizophrenia

United States, Brazil, Mexico
University of California, Berkeley
University of California, San Francisco

Withdrawn

Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT Inhibitor

Addiction

United States

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