Search clinical trials for: Double Blind Randomized Controlled Trial

Total 52549 results

Population Council

Completed

A Two-part Trial Assessing the Effects of 7α-methyl-19-nortestosterone (MENT) on Blood Pressure in Normal Men: an Open-label Pilot Study Followed by a Randomized, Double-blind, Placebo-controlled Study

Blood Pressure

United States
Cristália Produtos Químicos Farmacêuticos Ltda.
Newco Trials Pesquisa Científica Ltda

Withdrawn

Phase III, Evaluate Noninferiority Between Levobupivacaine and Bupivacaine in Spinal Anesthesia.

Orthopedic Disorder of Spine

Brazil
Casa de Saúde santa Marcelina

Completed

Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial

Dyslipidemias | Menopause | Homocystinaemia
Tissue Therapies Ltd.

Withdrawn

A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro® ECM to Placebo in Patients With Venous Leg Ulcers

Venous Leg Ulcer
CHU de Quebec-Universite Laval
Quebec Breast Cancer Foundation

Completed

Vitamin D and Mammographic Breast Density (EVIDENSE)

Breast Cancer

Canada
Teva Pharmaceuticals USA

Completed

A Randomized, Double-Blind, Parallel-Group, Vehicle-Controlled, Multicenter Study Comparing Diclofenac Sodium Gel, 3% to Solaraze® Gel, 3% in the Treatment of Actinic Keratosis on the Face or Bald Scalp

Actinic Keratosis

United States
Mairead Kiely PhD
European Commission

Completed

Nutritional Requirements for Vitamin D in Pregnant Women (DMAT)

Vitamin D Deficiency

Ireland
University of North Carolina, Chapel Hill

Terminated

Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears

Rotator Cuff Tear

United States
Merck Sharp & Dohme LLC

Completed

A Placebo-Controlled, Double-Blinded, Randomized Trial of Remicade in Korean Patients With Rheumatoid Arthritis Despite Methotrexate (Study P04280)(COMPLETED)

Arthritis, Rheumatoid
Astellas Pharma Inc
Astellas Pharma Taiwan, Inc.

Completed

A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea

Nausea | Vomiting

Taiwan
University of Milan

Unknown

Efficacy of Fermented Rice Flour for the Treatment of Atopic Dermatitis: Randomized, Double-blind Controlled Trial

Child | Dermatitis, Atopic | Infant

Italy
Hospital de Clinicas de Porto Alegre
Secretaria Nacional de Políticas sobre Drogas (SENAD)

Unknown

Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial.

Alcohol Addiction | Cocaine Addiction

Brazil
American Regent, Inc.

Terminated

Randomized Double Blind Placebo Controlled Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopath

Calciphylaxis | Calcific Uremic Arteriolopathy

United States
University of Aarhus
Albert Einstein College of Medicine; Pfizer; GCP-unit at Aarhus University Hospital... and other collaborators

Completed

Pregablin for Anxiety-comorbidity in Patients With Schizophrenia (PACS)

Schizophrenia | Anxiety-comorbidity to Schizophrenia

Denmark
Kocaeli University

Completed

Intravenous Metoclopramide in the Acute Treatment of Migraine: A Double-blind, Randomized, Placebo-controlled Trial

Migraine Disorders

Turkey
H. Lundbeck A/S

Completed

Dose-finding Study With Lu AA24530 in Major Depressive Disorder

Major Depressive Disorder

Ukraine, Lithuania, France, Austria, Russian Federation, Australia, Belgium, Canada, Czech Republic, Finland, India, Korea, Republic of, Malaysia, Norway, Philippines, Serbia, Sweden
Humanetics Corporation
National Center for Complementary and Integrative Health (NCCIH); James J....

Completed

A Single Site, Randomized, Double-blind, Placebo Controlled Trial of NIC5-15 in Subjects With Alzheimer's Disease

Dementia | Alzheimer's Disease

United States
Chiang Mai University

Unknown

Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial

Osteoarthritis of the Knee

Thailand
AstraZeneca
Ironwood Pharmaceuticals, Inc.

Completed

A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) (D5630C00001)

Irritable Bowel Syndrome With Constipation (IBS-C)

United States, Australia, China, New Zealand, Canada
University of Eastern Finland

Completed

The Effect of a High-dose Oral Vitamin D3 Bolus on Serum 25(OH)D3 and Vitamin D Receptor Target Gene Expression (VitDbol)

Vitamin D Receptor Target Gene Expression | Serum 25(OH)D Concentration

Finland
Isfahan University of Medical Sciences

Completed

Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial

Knee Arthroplasty, Total

Iran, Islamic Republic of
GZA Ziekenhuizen Campus Sint-Augustinus

Completed

Large-scale Prospective Double-blind Randomized Controlled Trial of Pecs II Block for Breast Surgery

Pain, Postoperative | Postoperative Nausea and Vomiting

Belgium
Yonsei University

Completed

Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial

Chronic Cough Caused by Gastroesophageal Reflux

Korea, Republic of
Indonesia University

Unknown

The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial

Pre-frail Elderly

Indonesia
Targeted Medical Pharma

Terminated

A Randomized Double-Blind Placebo Controlled Trial to Determine the Status of Post Knee Chondroplasty Patients Administered Theramine Versus Placebo in Addition to Post Surgery Analgesics

Knee Pain | Knee Chondroplasty

United States
Seoul National University Hospital
Ministry of Food and Drug Safety, Korea

Completed

Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism

REM Sleep Behavior Disorder

Korea, Republic of
Ottawa Hospital Research Institute

Completed

TNF-alpha Antagonists for AECOPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

COPD Exacerbation
Daewoong Pharmaceutical Co. LTD.

Completed

A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb Spasticity

Stroke | Spasticity

Korea, Republic of
DePuy Spine

Completed

A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc Degeneration

Degenerative Disc Disease

United States
DSM Nutritional Products, Inc.
Abbott Nutrition

Completed

Effects of Lutein on Learning and Memory in Chronically Stressed Subjects and in an Acute Stressful Situation (TSST - Trier Social Stress Test): A Randomized, Double-blind, Placebo-controlled Trial) (MemLearn)

Healthy But Chronically Stressed

Germany
Bundang CHA Hospital

Unknown

Clinical Trial to Evaluate the Potential Efficacy and Safety of Human Umbilical Cord Blood and Plasma

Aging

Korea, Republic of
Portuguese Oncology Institute, Coimbra

Completed

Simethicone and N-acetylcysteine in Upper Endoscopy - Prospective Double-blinded Randomized Controlled Trial

Gastric Mucosal Lesion

Portugal
Federal University of Paraíba

Completed

A Randomized, Controlled, Double-blind Clinical Trial of Surinam Cherry Dentifrice With Anti-gingivitis Properties

Gingivitis
McMaster University
McMaster Surgical Associates

Completed

Effect of Simethicone on Postoperative Ileus in Patients Undergoing Colorectal Surgery

Ileus | Postoperative Ileus

Canada
Fundació Sant Joan de Déu
Instituto de Salud Carlos III

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity

Obesity
EMD Serono
Merck KGaA, Darmstadt, Germany

Completed

Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START) (START)

Non-small Cell Lung Cancer

United States, Sweden, Australia, Czech Republic, France, Italy, Korea, Republic of, Russian Federation, Spain, United Kingdom, Germany, China, Poland, Romania, Denmark, Hong Kong, Canada, Austria, Belgium, Hungary, Israel, Nether... and more
Biolab Sanus Farmaceutica

Withdrawn

A Randomized, Double Blind, Placebo Controlled Trial L-carnitine and Piracetam in the Treatment of Weakness, Muscle Fatigue and Muscle Pain in the Postpoliomyelitis Syndrome

Postpoliomyelitis Syndrome

Brazil
University of Medicine and Dentistry of New Jersey
Scios, Inc.

Withdrawn

Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF

Pulmonary Edema | Dyspnea | Heart Failure, Congestive

United States
AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™) for the Treatment of Post-Operative Pain in Patients After Open Abdominal Surgery

Post-Operative Pain

United States
Shiraz University of Medical Sciences

Completed

Efficacy of Nepeta Menthoides Extract on Anxiety of Patients With Depression: a Double-blind Randomized Controlled Clinical Trial

Depression | Anxiety
Medical University of Vienna

Completed

A Prospective Randomized Double-Blinded Placebo Controlled, Explorative Phase I Trial to Investigate the Safety and Tolerability of Two Different Doses of Topically Administered APOSEC™ in Healthy Male Subjects With Artificial Dermal Wounds

Healthy | Artificial Dermal Wound

Austria
University Hospital, Clermont-Ferrand

Unknown

Impact of 50% Nitrous Oxide Inhalation on Pain and Anxiety Induced by Lumbar Puncture: a Double-blind Randomized Controlled Trial

Lumbar Puncture

France
Harokopio University
University College Cork; FrieslandCampina

Completed

Investigation of Vitamin D3 Enriched, Reduced-fat Yellow Cheese Efficacy to Prevent Vitamin D Deficiency

Hypovitaminosis D | Deficiency of Micronutrients

Greece
University Hospital, Basel, Switzerland

Completed

Study Into the Effect of Ibandronate for the Treatment of Bone Marrow Edema in Relation to Spontaneous or Non-traumatic Osteonecrosis of the Knee: A Randomized Double-blind, Placebo-controlled Trial

Osteonecrosis of the Knee | Bone Marrow Edema of the Knee

Switzerland
The First Affiliated Hospital of Anhui University...

Completed

A Clinical Study of Xin'an Medicine in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

China
Beijing 302 Hospital

Unknown

A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial

Chronic Hepatitis B | Liver Fibrosis

China
Federal University of Minas Gerais

Completed

A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy

Heart Failure | Chagas Cardiomyopathy | Dilated Cardiomyopathy

Brazil
University of Seville

Completed

Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs

Gingivitis
Yale University
Sunovion

Completed

Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia

Schizophrenia | Schizoaffective Disorder | Insomnia | Sleep Disorders

United States
SK Life Science, Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy

United States

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