Search clinical trials for: Early phase

Total 28127 results

Biogen

Terminated

Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease (TANGO)

Alzheimer's Disease

United States, Spain, Italy, Australia, France, Poland, Germany, Japan, Sweden
European Organisation for Research and Treatment...

Active, not recruiting

Pleurectomy/ Decortication (P/D) Preceded or Followed by Chemotherapy in Patients With Early Stage MPM

Malignant Pleural Mesothelioma

Belgium, Netherlands
University of Sao Paulo General Hospital
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Active, not recruiting

Robotic Therapy and Brain Stimulation in the Early Phase After Stroke

Stroke

Brazil
Ottawa Hospital Research Institute
GlaxoSmithKline; Hamilton Health Sciences Corporation; London Regional Cancer... and other collaborators

Completed

A Phase II Window of Opportunity Trial of PRMT5 Inhibitor, GSK3326595, in Early Stage Breast Cancer (OTT-19-06)

Breast Cancer

Canada
Elixiron Immunotherapeutics Inc.
Parexel

Completed

A Study to Evaluate the Safety, Tolerability and Amount of EI-1071 in Blood in Healthy Volunteers

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of LY3502970 in Healthy Overweight and Obese Participants

Healthy | Obese

United States
Regulus Therapeutics Inc.

Completed

A Study of RGLS8429 in Healthy Volunteers

Healthy Volunteers

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Early Phase 2 Clinical Study of TS-142 in Patients With Insomnia Disorder

Insomnia Disorder

Japan
Sheffield Hallam University
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

The Effects of Posture on Cerebral Blood Flow Velocity During the Acute Phase of Stroke

Ischemic Stroke | Cerebrovascular Accident | Acute Stroke | Haemorrhagic Stroke

United Kingdom
Eiger BioPharmaceuticals

Completed

Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia (PREVENT)

Postbariatric Hypoglycemia

United States
Dynacure

Withdrawn

Early Phase Human Drug Trial to Investigate DYN101 in Participants 2 to 17 Years With Centronuclear Myopathies (DyNaMic)

Centronuclear Myopathy

Germany, France
SAb Biotherapeutics, Inc.
Department of Health and Human Services; JPEO, Chemical, Biological, Radiological...

Completed

Safety, Tolerability, and Pharmacokinetics of SAB-185 in Healthy Participants

COVID-19 | SARS-CoV2

United States
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers

Healthy Volunteers

United States
Sun Yat-sen University

Completed

Combined Treatment of Sintilimab, Peg-aspargase Plus Anlotinib in NK/T Cell Lymphoma

Radiotherapy | Sintilimab | Anlotinib | Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type | Early Stage | Peg-aspargase | Phase Two | Open

China
Universitätsmedizin Mannheim

Completed

Prospective Phase II Study of Intraoperative Radiotherapy (IORT) in Elderly Patients With Small Breast Cancer (TARGIT-E)

Neoplasms | Breast Neoplasms | Breast Diseases | Neoplasm Recurrence, Local

Germany
Dompé Farmaceutici S.p.A

Completed

A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males

No Condition

United Kingdom
Daré Bioscience, Inc.

Completed

Pharmacokinetic Study of DARE-BV1

Bacterial Vaginosis

United States
Universiteit Antwerpen
University Hospital, Antwerp

Completed

Exoskeleton-assisted Training to Accelerate Walking Recovery Early After Stroke: the TARGET Phase II Study (TARGET)

Stroke | Paresis | Gait, Hemiplegic

Belgium
Lawson Health Research Institute

Active, not recruiting

A Phase II Trial Measuring the Integration of Stereotactic Radiotherapy Plus Surgery in Early Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

Canada
AMAG Pharmaceuticals, Inc.

Completed

Study to Evaluate Rate of Nausea in Healthy Premenopausal Female Subjects Treated With Single Dose of Bremelanotide Alone or With Zofran

Nausea

United States
Stefano Brunelli

Terminated

Early Radial Shock Waves Treatment on Spasticity in Patients With Stroke in Sub-acute Phase

Rehabilitation | Spasticity, Muscle | Extracorporeal Shockwave Therapy

Italy
Heptares Therapeutics Limited

Terminated

A Study in Healthy Subjects to Assess the Safety, Tolerability and Pharmacokinetics of HTL0022562

Healthy

United Kingdom
Mylan Inc.
Mylan GmbH

Completed

Phase I - Pharmacokinetic Comparability Study in Healthy Male Volunteers

Healthy

Netherlands
Mylan Pharma UK Ltd.

Completed

Bioequivalence Study to Assess Systemic Exposure of FP and SAL FDC From Different DPIs

Asthma | COPD

United States
Takeda

Completed

A Phase 3, Long-term, Extension Study of TVP-1012 (1 mg) in Early Parkinson's Disease Participants

Parkinson's Disease

Japan
Takeda

Completed

A Phase 3 Study of TVP-1012 (1 mg) in Early Parkinson's Disease Patients

Parkinson's Disease

Japan
Institute of Cancer Research, United Kingdom
Merck Sharp & Dohme LLC; National Institute for Health Research Biomedical...

Active, not recruiting

A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatment in Early Stage Triple Negative Breast Cancer Patients (c-TRAK-TN)

Triple Negative Breast Cancer

United Kingdom
Astellas Pharma Global Development, Inc.

Completed

A Study to Assess Bioequivalence of Fezolinetant Formulations in Healthy Female Participants

Healthy Volunteers

United States
National Cancer Center, Korea

Completed

Multicenter Phase III Trial of Laparoscopic Sentinel Node Biopsy

Early Gastric Cancer

Korea, Republic of
MacroGenics

Completed

Phase 1 Study of MGD010 in Healthy Subjects

Healthy Subjects

United States
Neurana Pharmaceuticals, Inc.

Completed

A Phase 1 PK Study of Tolperisone in Healthy Subjects

Healthy

United States
Genenta Science
IRCCS San Raffaele

Terminated

A Phase I/II Study Evaluating Temferon in Multiple Myeloma Patients With Early Relapse After Front Line Therapy (TEM-MM)

Multiple Myeloma

Italy
Dana-Farber Cancer Institute
Novartis Pharmaceuticals

Completed

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Hypopharyngeal Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Early Invasive Cervical Squamous Cell Carcinoma | Cancer of Nasopharynx | Carcinoma of Larynx

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Nilotinib as First-line Treatment of Ph+ CML in Early Chronic Phase (CML0307)

Chronic Myeloid Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Active, not recruiting

Front-line Treatment of BCR-ABL+ Chronic Myeloid Leukemia (CML) With Dasatinib (CML1113)

Chronic Myeloid Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia (CML0408)

Leukemia

Italy
Ono Pharmaceutical Co. Ltd
Parexel

Completed

A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy Participants

Neurodegenerative Diseases

United Kingdom
MedinCell S.A

Completed

Exploratory Ph I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19

Covid19

United Kingdom
Regulus Therapeutics Inc.

Completed

A Study of RGLS4326 in Patients With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney Disease, Autosomal Dominant

United States
Five Prime Therapeutics, Inc.

Terminated

Phase 1 Single and Multiple Dose Study of FPA008 in Healthy Volunteers and Rheumatoid Arthritis Subjects

Healthy | Rheumatoid Arthritis

Hungary, Netherlands, Poland
Universidad Peruana Cayetano Heredia
Barcelona Institute for Global Health

Completed

Randomized Phase IIA Clinical Trial to Evaluate the Efficacy of Ivermectin to Obtain Negative PCR Results in Patients With Early Phase COVID-19 (SAINT-PERU)

Coronavirus Infection | Covid19 | SARS-CoV Infection

Peru
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP)

Smoking

Canada
AZTherapies, Inc.
APCER Life Sciences; PharmaConsulting Group; KCAS Bio

Completed

Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease (COGNITE)

Alzheimer's Disease

United States, Australia, Poland, Czechia, Hungary, Bulgaria, Canada
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Phase III Study to Evaluate the Safety, Tolerance, and Efficacy of Early Treatment With Zidovudine (AZT) in Asymptomatic Infants With HIV Infection

HIV Infections

United States, Puerto Rico
H. Lundbeck A/S

Completed

Lu AF82422 in Healthy Non-Japanese and Japanese Subjects and in Patients With Parkinson's Disease

Healthy | Parkinson Disease

United States
Sheba Medical Center
Weizmann Institute of Science

Withdrawn

Glycemic Index Variations In the Early Period Following Bariatric Surgery

Diabetes Mellitus | Bariatric Surgery Candidate

Israel
Novartis Pharmaceuticals

Completed

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer (EarLEE-1)

Breast Cancer

United States
University of Leeds
The Leeds Teaching Hospitals NHS Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Completed

ePRIME: Patient-Reported AEs in Early Phase Trials

Cancer

United Kingdom
Trevena Inc.

Terminated

A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250

Migraines

United Kingdom

Search clinical trials for: Early phase

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