Search clinical trials for: Evaluation of QT Interval

Total 432455 results

Gilead Sciences

Completed

Effect of Oral GS-6615 on Dofetilide-Induced QT Prolongation, Safety, and Tolerability in Healthy Adults

Long QT Syndrome

United States
AstraZeneca
Eli Lilly and Company

Completed

A Safety Study to Assess the Effects of Therapeutic and Supratherapeutic Exenatide Concentrations on QT Interval in Healthy Subjects

Healthy Subjects

United States
Kowa Research Institute, Inc.

Completed

A Thorough Corrected QT Interval Trial

Dyslipidemia

United States
Severance Hospital

Completed

The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation in Normotensive and Hypertensive Patients

Intubation, Intratracheal

Korea, Republic of
Genfit
Eurofins Optimed; PhinC Development; CardiaBase

Completed

Phase I Study to Evaluate the Effect of GFT505 on QT/QTc Interval in Healthy Volunteers

Healthy Volunteers

France
FHI 360
Cornell University; EngenderHealth; Kenya National AIDS & STI Control Programme; Ministry of Medical Services, Kenya

Completed

Evaluation of Healing at Three Time Intervals and Potential for Spontaneous Detachment

Male Circumcision

Kenya
Hannover Medical School

Unknown

QT-Prolongation in Lung Transplantation (TX-QTC)

Disorder Related to Lung Transplantation

Germany
AstraZeneca
Eli Lilly and Company

Completed

Electrophysiological Effects of a Single 10 μg Dose of Exenatide on the 12-Lead Electrocardiogram QT Interval in Healthy Subjects

Healthy Subjects

United Kingdom
Nantes University Hospital

Completed

Effect of Domperidone on QT Interval in Premature Infants

Prematurity and Feeding Intolerance

France
Ankara University

Completed

Comparison of Calcium Channel Blockers and Beta Blockers on Tourniquet-induced Hypertension During Intravenous Regional Anesthesia

Hypertension
Janssen Scientific Affairs, LLC
Bausch Health Americas, Inc.; Cipher Pharmaceuticals Inc.

Completed

A Dose Ranging Escalation Study of Tramadol Hydrochloride in Healthy Volunteers

Healthy

United States
Vanderbilt University
National Institutes of Health (NIH); Wake Forest University Health Sciences

Completed

QT Variability Pre and Post Cardioversion (DCCV)

Atrial Fibrillation

United States
Vanderbilt University
National Institutes of Health (NIH); Wake Forest University Health Sciences

Completed

Effects Rapid Atrial Pacing Has on the Electrocardiogram (ECG) in Patients With Dual Chamber Pacemakers

Prolonged QT Interval

United States
University of Michigan
Renal Research Institute

Completed

Defining The Role Of Dialysate Magnesium In Arrhythmogenicity On Dialysis

Chronic Kidney Disease | Arrhythmia

United States
Knopp Biosciences

Completed

Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of the QRS Complex to the End of the T Wave Corrected for Heart Rate)

Amyotrophic Lateral Sclerosis

United States
Gilead Sciences

Completed

Study of the Effect of GS-6615 in Subjects With LQT-3

Long QT Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteers

Tuberculosis

United States
Hillerod Hospital, Denmark
Rigshospitalet, Denmark; University of Southern Denmark; UNEEG Medical A/S

Completed

Recurrent Hypoglycaemia in Type 1 Diabetes (HypoNeuro)

Hypoglycaemia

Denmark
AstraZeneca

Completed

Assessing the Pharmacokinetics of NKTR-118 in Subjects With Renal Impairment Compared to That in Subjects With Normal Renal Function

Renal Impairment

United States
AstraZeneca

Completed

A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects

Amount of NKTR-118 in Blood | Variation in the Heart's Electrical Cycle

United States
AstraZeneca

Completed

Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects

Healthy

United States
Boehringer Ingelheim

Completed

Influence of Telmisartan and Lacidipine, Combined or Alone, on QT Interval in Healthy Volunteers

Healthy
Boehringer Ingelheim

Completed

Influence of Pramipexole on the QT Interval of the ECG in Healthy Male and Female Volunteers

Healthy
FORUM Pharmaceuticals Inc
Quintiles, Inc.

Completed

Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects (TQT)

Healthy Subjects | Cardiac Repolarization
Boehringer Ingelheim

Completed

Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Electrophysiological Effects of Tipranavir Co-administered With Ritonavir on the QT Interval in Healthy Female and Male Subjects

Healthy
Purdue Pharma LP

Completed

The Effect of Hydrocodone Bitartrate (HYD) Extended-Release Tablets on QT /QTc Intervals in Healthy Adult Subjects

Healthy

United States
Lexicon Pharmaceuticals

Completed

A Thorough QT Study of Telotristat Etiprate

QT Interval

United States
Richmond Pharmacology Limited

Completed

Food and Insulin Effect on QT/QTC Interval of ECG (C11035)

Effects of Different Meals on the QT/QTc Interval | Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use | C-Peptide Effects on the QT/QTc Interval | Moxifloxacin ECG Profile in Fed and Fasted State | Japanese vs. Caucasian TQT Comparison

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Phase 1, QT/QTC Interval Study in Healthy Subjects

Cystic Fibrosis

Netherlands
Boehringer Ingelheim

Completed

Assessment of the Effect of Empagliflozin (BI 10773) as Single Dose on the QT Interval in Healthy Female and Male Subjects

Healthy

Germany
Bristol-Myers Squibb

Completed

Study to Determine the Effect of BMS-791325 on the ECG QTcF Interval in Healthy Subjects

Hepatitis C

United States
Boehringer Ingelheim

Completed

Assessment of the Effect of BI 201335 on the QT Interval in Healthy Female and Male Subjects

Healthy
Boehringer Ingelheim

Completed

Effect of BI 1356 as Single Dose on the QT Interval in Healthy Female and Male Subjects

Healthy
C.R.Darnall Army Medical Center
Madigan Army Medical Center

Completed

Ondansetron and the QT Interval In Adult Emergency Department Patients

Ondansetron

United States
Boehringer Ingelheim

Completed

Assessment of Electrophysiological Effects of Dabigatran Etexilate as Single Dose on the QT Interval in Healthy Female and Male Subjects.

Healthy
KU Leuven
Agentschap voor Innovatie door Wetenschap en Technologie

Completed

Drug Interactions With Risk of QT-prolongation in a General Hospital

QT-prolongation

Belgium
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs

Healthy

Korea, Republic of
Seoul National University Hospital

Completed

The Effect of Inhalation Agent on the QTc Interval During Liver Transplantation: Sub Study (NCT01886664)

Anesthesia, General

Korea, Republic of
Cephalon

Completed

Study to Assess the Effect of Treatment With Bendamustine in Combination With Rituximab on QT Interval in Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL)

Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma

Australia, Canada, United States
Haiyan Li
Peking University; Food and Drug Administration (FDA); Spaulding Clinical Research... and other collaborators

Unknown

Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers

Cardiac Toxicity

United States, China
Johnson & Johnson Pharmaceutical Research & Development...
PharmaMar

Completed

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

Solid Tumor

France, United States, Belgium, India, Korea, Republic of, Russian Federation, Spain
National Institute of Allergy and Infectious Diseases...

Withdrawn

Effects of SQ109 on QTc Interval in Healthy Subjects

Tuberculosis

United States
Children's Hospital, Dziekanów Leśny, Poland

Completed

Evaluation of Immunological Disorders of T Lymphocytes and Endocrinological Disorders as Pathogen Factors in Patients With Metaplasia of Urinary Bladder

The Follow-up Duration Was 1-8 Years. | The Main Reasons Behind Visiting the Hospital Were Recurrent Urinary Tract Infection, | Urinary Urgencies, Pollakiuria, Difficulty in Initiating Micturition, Pain in Hypogastrium, | Night Wetting and Day Wetting, Menstruation's Disorders, Urolithiasis... and other conditions

Poland
Allergan
MAP Pharmaceuticals, Inc., a wholly owned subsidiary of Allergan

Completed

QT Intervals Study to Compare the Acute Effects of Orally Inhaled Dihydroergotamine (DHE), Oral Moxifloxacin, and Placebo

Healthy

United States
Centre hospitalier de l'Université de Montréal...

Completed

Comparison of the QT/QTc Interval Between an Outpatient HIV-Infected Population on Antiretroviral Therapy and Two Large HIV-Negative Cohorts (QTVIE)

QT and Corrected QT Intervals Prolongation in HIV Positive Subjects Treated With an Antiretroviral Regimen

Canada
Brandon G. Busbee, MD
Genentech, Inc.

Completed

Evaluation of Dosing Interval of Higher Doses of Ranibizumab (BGB/IST)

Macular Degeneration | Choroidal Neovascularization

United States
Bristol-Myers Squibb

Withdrawn

Efficacy and Safety Evaluation of a Treatment Consisting of Peg Interferon Alfa + Ribavirin + Daclatasvir in HCV Genotype 1 and 4 Treatment naïve Patients (COMMAND-Asia)

Hepatitis C
University of Oklahoma

Withdrawn

Heart Safety Study of Ondansetron in Children Receiving Chemotherapy

Malignant Childhood Neoplasm

United States
Sanofi

Completed

An Open-label Study Investigating the Disposition and QT/QTc Interval Effects of 400 mg [14C]-Iniparib(3.7 MBq, 100 µCi)

Advanced Solid Tumors

United States

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