Search clinical trials for: Human challenge

Total 24969 results

Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Novice Driver Education and Crash Reduction

Injuries | Risk Reduction Behavior | Accident, Traffic | Development, Adolescent
IRCCS Ospedale San Raffaele

Not yet recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Rare Diseases | Corneal Neovascularization | Limbal Stem Cell Deficiency | Aniridia | Neurotrophic Keratopathy | Ocular Cicatricial Pemphigoid | Ocular Graft-versus-host Disease | EEC Syndrome
Vivheart s.r.l.

Recruiting

EasyCrossTM Device-Self-centering Catheter (VIV-FIH)

Transcatheter Aortic Valve Replacement (TAVR)

Italy
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Acquired Pure Red Cell Aplasia | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Acquired Amegakaryocytic Thrombocytopenia
Dalhousie University
University of Maiduguri Teaching Hospital; Brooks Insights

Not yet recruiting

RESETTLE-IDPs: Life-Skills Education and Psychosocial Resilience Building for Displaced Nigerians (RESETTLE-IDPs)

Mental Health | Implementation Science | Psychosocial Functioning | Conflict | Global Health
Serum Institute of India Pvt. Ltd.

Recruiting

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Hepatitis B Immunization | Diptheria Immunization | Tetanus Immunization | Pertussis Immunization | Haemophilus Influenzae Type B Immunization | Polio Immunization

Bangladesh, India
University of Trás-os-Montes and Alto Douro
Hospital Centre Hospitalar de Trás-os-Montes e Alto Douro; Research Center...

Not yet recruiting

Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Portugal
NICHD Pelvic Floor Disorders Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Training for Urinary Leakage Improvement After Pregnancy (TULIP)

Urinary Incontinence | Delivery Complication

United States
McMaster University

Not yet recruiting

Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma (MATT)

Mild Asthma

Canada
University of Texas, El Paso
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas

Physical Activity | Activity Trackers

United States
University of Leicester
University Hospitals, Leicester

Not yet recruiting

Ischaemic Lesions in Acute Intracerebral Haemorrhage (CHALLENGE-ICH)

Intracerebral Haemorrhage
Medinol Ltd.

Not yet recruiting

First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease (CHAMPIONSHIP)

Popliteal Artery Stenosis | Superficial Femoral Artery Stenosis
University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

Effectiveness and Tolerability of Eptinezumab (TACHIS)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
Istituto Clinico Humanitas

Not yet recruiting

Applicability of Enhanced Recovery After Surgery Protocols in the Therapeutic Endoscopy Suite (ERATE)

Colorectal Endoscopic Submucosal Dissection

Italy
Casa Sollievo della Sofferenza IRCCS
IRCCS Ospedale San Raffaele

Not yet recruiting

Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer

Lung Neoplasms | Progression
M.D. Anderson Cancer Center

Not yet recruiting

Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)

Hormone Receptor-positive Human Epidermal Growth Factor 2-negative | Metastatic Invasive LObular Carcinoma

United States
Elisa María Cubiles Montero de Espinosa
Andalusian Network for Design and Translation of Advanced Therapies

Recruiting

Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIOCLEFT in the Treatment of Cleft Palate.

Cleft Lip and Palate

Spain
University College Dublin
St Vincent's University Hospital, Ireland; Mater Misericordiae University Hospital and other collaborators

Recruiting

The All Ireland Infectious Diseases Cohort Project (AIID)

Infectious Disease

Ireland
Assistance Publique - Hôpitaux de Paris
Institut Curie; Centre National de la Recherche Scientifique, France; Collège...

Not yet recruiting

Mechanics of Human Pre Implantation Development (MECANEMB)

Infertility
University of Pennsylvania
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia (APPLE)

Pre-Eclampsia | Pregnancy Loss

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...
EHE Rare Cancer Charity UK

Recruiting

The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN) (EHE)

Sarcoma,Soft Tissue | Epithelioid Hemangioendothelioma

United Kingdom, Italy, Denmark, Spain, Sweden, Austria, Germany, France, Norway, Poland
University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment (RAISE)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
Huashan Hospital
Chinese Academy of Sciences

Not yet recruiting

A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording

Cognition

China
Oregon Health and Science University

Not yet recruiting

DBS TaT in Peer-assisted Telemedicine for Hepatitis C

Hepatitis C
Innovation Research & Training
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships

Communication | Parent-Child Relations | Parenting

United States
University Hospital, Tours

Not yet recruiting

Collection of Primary Human (BIONOSE)

Nasal Disease
University of Cologne

Recruiting

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges (RESERVE)

Hyponatremia

Germany
Raydiant Oximetry, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Trans-Abdominal Fetal Pulse Oximetry - EFS-IDE

Oxygen Deficiency | Fetal Complications | Fetal Hypoxia | Fetal Conditions | Fetal Distress | Labor (Obstetrics)--Complications | Labor Fetal Anoxia

United States
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Johns Hopkins University
National Institutes of Health (NIH); Desmond Tutu HIV Foundation

Not yet recruiting

Universal Test and Connect for HIV Service Delivery in South Africa (UTC-SA)

Human Immunodeficiency Virus | Emergency Department | Pre-Exposure Prophylaxis | South Africa
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer (POMPPR)

Pain, Postoperative | Anxiety | Sleep Disturbance | Preoperative | Midazolam

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment

Radiotherapy; Complications | DTC - Differentiated Thyroid Cancer | Thyroid Stimulating; Hormone, C

China
Hospital Mutua de Terrassa
Germans Trias i Pujol Hospital; Hospital Arnau de Vilanova; Fundació Institut...

Not yet recruiting

Transvaginal Human Acellular Dermal Matrix for Prolapse Treatment

Prolapse; Female | Prolapse Genital | Prolapse Uterovaginal
Vietnam Viral Hepatitis Alliance
University of Medicine and Pharmacy at Ho Chi Minh City; Le Van Thinh Hospital...

Not yet recruiting

DEcentralize Testing, Education, and Linkage to Care by Using Electronic Best Practice Advisory for Hepatitis B (DETECT-B) (DETECT-B)

Viral Hepatitis B
Washington D.C. Veterans Affairs Medical Center

Recruiting

Low Intensity Focused Ultrasound for Tobacco Use Disorder: High Resolution Targeting of the Human Insula (LIFU_TUD)

Tobacco Use Disorder

United States
University of Auckland, New Zealand
Health Research Council, New Zealand; Auckland City Hospital; Kitea Health Ltd

Not yet recruiting

First-in-human Trial of Home Brain Pressure Measured Using Kitea ICP Sensor, Placed During Hydrocephalus Shunt Surgery. (HomeICP)

Hydrocephalus

New Zealand
CDR-Life AG

Recruiting

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

Select Advanced Solid Tumors

United States, Denmark
Lakehead University
Illinois Institute of Technology, Chicago, USA

Recruiting

Honest, Open, Proud - College for Post-Secondary Students With Mental Health Challenges

Mental Health Issue | Stigmatization | Disclosure

Canada
York University
University of Alberta; Australian Catholic University; Social Sciences and Humanities...

Not yet recruiting

Tackling Two of the Most Important Unresolved Tasks in Reading Intervention

Dyslexia, Developmental
University of Connecticut
Department of Health and Human Services (DHHS) Administration for Community... and other collaborators

Not yet recruiting

Evaluating an Enhanced Home-delivered Meal Program on Older Adults' Health and Well-being

Quality of Life | Food Insecurity | Loneliness | Diet, Healthy
Signati Medical Inc

Recruiting

A Safety Study in Human Subjects Evaluating the Use of the Signati System for Vasectomy

Vasectomy

United States
Mediar Therapeutics
ICON plc

Recruiting

A First-in-Human Safety Trial of MTX-463

Healthy

United States
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Babol University of Medical Sciences

Not yet recruiting

Role of NLRP6 in Chronic Periodontitis

Chronic Periodontitis
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Futuros Fuertes 2.0

Obesity, Childhood

United States
Celgene
Bristol-Myers Squibb

Recruiting

A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation (KarMMa-9)

Multiple Myeloma

Austria, United States, Spain, Australia, Japan, France, Israel, Italy, Canada, Greece, Belgium, Norway, Romania, Czechia, Denmark, Germany, Korea, Republic of, United Kingdom, Poland
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

Effectiveness and Clinical Outcomes of Long-term Bulevirtide Monotherapy in Patients With HDV-related Compensated Cirrhosis (SAVE-D)

Hepatitis D

Italy
Chinese PLA General Hospital

Not yet recruiting

Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.

PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Undifferentiated Carcinoma | Recurrent Ovarian Clear Cell Adenocarcinoma | Recurrent Ovarian Undifferentiated Carcinoma and other conditions

Search clinical trials for: Human challenge

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