Search clinical trials for: Plasminogen

Total 337 results

Cerevast Therapeutics, Inc.

Terminated

Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke (CLOTBUST-ER)

Acute Ischemic Stroke

United States
Johns Hopkins University

Completed

Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage

Cerebral Hemorrhage

United States
University of Virginia
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)

Stroke

United States
Kaiser Permanente
Genentech, Inc.

Completed

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses

Abdominal Abscess | Pelvic Abscess

United States
Children's Mercy Hospital Kansas City

Completed

Treatment of Abdominal Abscesses With or Without Fibrinolysis

Abdominal Abscess | Tissue Plasminogen Activator

United States
The Second Artillery General Hospital
Hunan Rui Kang Tong technology development co., LTD

Unknown

Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke

Ischemic Cerebrovascular Accident
ThromboGenics

Completed

A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)

Vitrectomy

United States
ThromboGenics

Completed

Trial of Microplasmin Intravitreal Injection for Non-surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-006) Trial.

Vitreomacular Adhesion

United States
ThromboGenics

Completed

A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME) (MIVI-II)

Diabetic Macular Edema

Spain, Belgium, United Kingdom, Italy, Netherlands, Germany
ThromboGenics

Completed

Trial of Microplasmin Intravitreal Injection for Non-Surgical Treatment of Focal Vitreomacular Adhesion. The MIVI-TRUST (TG-MV-007) Trial.

Vitreomacular Adhesion

United States, Spain, United Kingdom, Germany, Belgium, Czech Republic, Poland
ThromboGenics

Completed

A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt)

Vitreomacular Traction

Belgium, Germany
ThromboGenics

Completed

The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV) (MIVI-10)

Vitrectomy

Belgium
Rigshospitalet, Denmark

Completed

Evaluation of a New Radiotracer (64Cu-DOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography

Breast Cancer | Prostate Cancer | Urinary Bladder Cancer

Denmark
Wuhan General Hospital of Guangzhou Military Command

Unknown

Outcome of Intravenous Thrombolysis for Stroke Patients in the 3-4.5 Hour Time Window

Stroke
Rabin Medical Center

Unknown

Perfusion Computer Tomography: Imaging and Clinical Validation Following Reperfusion Therapy in Acute Ischaemic Stroke

Ischemic Stroke

Israel
The University of Texas Health Science Center,...
Genentech, Inc.

Completed

Safety of Intravenous Thrombolysis for Wake-up Stroke (Wake-Up Stroke)

Ischemic Stroke

United States
ThromboGenics

Completed

Intravenous Administration of Microplasmin for Treatment of Acute Ischemic Stroke

Stroke, Acute

Germany, Belgium, Austria
Richard Chang, M.D.
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins

Acute Deep Venous Thrombosis of the Lower Extremity

United States
University of Campinas, Brazil

Unknown

The Influence of Glycaemia and Insulinemia on Vasomotor Endothelial Function After Myocardial Infarction (INGLIVEF)

Myocardial Infarction

Brazil
Boehringer Ingelheim

Terminated

A Study of Pre-hospital Treatment of Acute Myocardial Infarction Based on Diagnosis by Interpretation of Remotely Acquired ECG and Thrombolysis With Accelerated Alteplase ( Actilyse®) (PHARAOH)

Myocardial Infarction
Boehringer Ingelheim

Completed

An International Observational Study of the Safety and Efficacy of Thrombolysis in Stroke

Stroke
Boehringer Ingelheim

Terminated

Protocol for Post Marketing Surveillance of Actilyse Vial

Stroke
Boehringer Ingelheim

Completed

Safe Implementation of Thrombolysis in Stroke - Monitoring Study

Stroke
Centocor, Inc.
Eli Lilly and Company

Completed

A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse)

Myocardial Infarction

United States, France, United Kingdom, Belgium, Germany, Spain, Poland, Bulgaria, Romania, Israel, Sweden, Canada, Czech Republic, Argentina, Austria, Denmark, Netherlands, South Africa, Switzerland
Boehringer Ingelheim

Completed

Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI) (ASSENT 3)

Myocardial Infarction
Boehringer Ingelheim

Completed

A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction
Niguarda Hospital

Completed

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS EXP)

Stroke | Cerebrovascular Accident

Italy
SOS Attaque Cérébrale

Terminated

Thrombectomy Under Reopro Versus Alteplase to Treat Stoke (TURANDOT)

Infarction, Middle Cerebral Artery

France
Kyorin University

Completed

Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Submacular Hemorrhage | Ruptured Retinal Arterial Macro Aneurysms

Japan
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-ER)

Stroke | Ischemic Stroke | Brain Infarction

United States
Genentech, Inc.

Completed

Cathflo Activase Pediatric Study

Dysfunctional Central Venous Access Devices (CVADS)
ThromboGenics

Terminated

Intra-arterial Microplasmin Administration in Patients With Acute Peripheral Arterial Occlusion

Arterial Occlusive Diseases

Belgium
ThromboGenics

Completed

Safety and Efficacy Study of Microplasmin in for Non-Surgical Treatment of Focal Vitreomacular Adhesion (MIVI-8)

Focal Vitreomacular Adhesion

Belgium
ThromboGenics

Completed

Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy

Eye Diseases | Vitreomacular Traction Maculopathy

Belgium, Netherlands
ThromboGenics
Bacchus Vascular

Terminated

Microplasmin Administered Via the Trellis-8 Infusion System for Treatment of Acute Iliofemoral DVT (MAX-DVT)

Deep Vein Thrombosis

Ireland
ThromboGenics

Terminated

Intra-arterial Microplasmin Administration in Patients With Acute Intracranial Vertebrobasilar Artery Occlusion (MITI-IA)

Stroke

Netherlands, Germany
Georgetown University
Johns Hopkins University; University of Alabama at Birmingham; University of... and other collaborators

Completed

Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities (ASPIRE)

Stroke

United States
University Health Network, Toronto

Terminated

Safety and Effectiveness of tPA in Intra-abdominal Abscesses

Abscess

Canada
Ahi Evren Chest and Cardiovascular Surgery Education...

Unknown

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism

Pulmonary Embolism

Turkey
Joseph Broderick
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Terminated

Interventional Management of Stroke (IMS) III Trial (IMSIII)

Stroke

Canada, United States, Switzerland, Germany, Spain, Netherlands, Australia, France
Queen's University

Completed

Urokinase Plasminogen Activator System in Benign Prostatic Hyperplasia

BPH

Canada
Ataturk University

Unknown

Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary Thromboembolism

This Study Will Provide Data Comparing Safety of LMWH Versus UFH in the Treatment of Acute PE Cases Who Require Thrombolytic Treatment.

Turkey
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS); Scripps Health

Withdrawn

Study for the Use of Alteplase in Patients Who Awaken With Stroke (AWOKE)

Ischemic Stroke

United States
Melbourne Health
Boehringer Ingelheim

Completed

Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET)

Stroke

Australia, New Zealand, Belgium, United Kingdom
Mayo Clinic

Completed

Early Mobilization of Ischemic Stroke Patients Within 24-hours After Intravenous-Tissue Plasminogen Activator (IV-tPA) (EMISTPA)

Ischemic Stroke

United States
University of Michigan
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Increasing Stroke Treatment Through Interventional Change Tactics Study (INSTINCT)

Stroke

United States
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3

Obesity

United States
Duke University
The Medicines Company

Withdrawn

Pre and or Post Operative Blood Pressure Control With Clevidipine (Cleviprexm Medicines Company) in Aortic Aneurysm / Dissection (Clevidipine)

Aorta Aneurysm | Dissection of Aorta

United States
National Institute of Neurological Disorders and...

Completed

Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST) (CATALIST)

Ischemic Stroke

United States
Niguarda Hospital

Completed

Local Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS)

Stroke | Cerebrovascular Accident

Italy

3

Subscribe