Search clinical trials for: Single ascending dose (SAD)

Total 26702 results

Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
Johann Wolfgang Goethe University Hospital

Completed

Evaluation of Bronchial Inflammation in Allergic Bronchopulmonary Aspergillosis (ABPA) (ABPA)

Cystic Fibrosis,

Germany
University of Calgary
Alberta Health services; 3M

Active, not recruiting

Peritoneal Vacuum Therapy to Reduce Inflammatory Response From Abdominal Sepsis/Injury (SAD)

Intra-abdominal Hypertension | Abdominal Compartment Syndrome

Canada
Ansun Biopharma, Inc.

Unknown

DAS181 for Patients With Severe Hospitalized Flu and SAD-RVs (COVID-19) (STOP-Flu)

Influenza Infection | SAD-RV Infection and COVID-19

China
Novo Nordisk A/S

Completed

Efficacy and Safety of Biphasic Insulin Aspart 30 FlexPen® in Insulin Naive Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Former Serbia and Montenegro
Hoffmann-La Roche

Completed

A Study of Rituximab in Combination With Chemotherapy in Relapsed/Refractory Follicular Lymphoma (REFLECT 2)

Lymphoma, Follicular

Serbia
Zai Lab Pty. Ltd.

Unknown

Study of the Tolerability and Pharmacokinetic of ZL-2102 With an Investigation of Food Effect in Healthy Male Subjects

Chronic Obstructive Pulmonary Disease | Asthma | Idiopathic Pulmonary Fibrosis

Australia
National Center for Advancing Translational Sciences...
Leidos Biomedical Research, Inc.; ICON Government and Public Health Solutions...

Not yet recruiting

GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects

COVID-19
Amolyt Pharma

Completed

AZP-3601 SAD and MAD Study in Healthy Subjects and Patients With Hypoparathyroidism

Chronic Hypoparathyroidism

Hungary, Netherlands
Qilu Pharmaceutical Co., Ltd.

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous FL058 and Meropenem in Healthy Subjects(SAD/MAD)

Healthy

China
AstraZeneca

Completed

Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 in Healthy Volunteers (SAD)

Healthy Volunteers

Germany
Omeicos Therapeutics GmbH

Completed

Safety and Pharmacokinetic Study of OMT-28 in Healthy Subjects

Healthy Volunteers

Germany
gicare Pharma Inc.

Completed

A Clinical Phase I Study on GIC-1001 in Healthy Volunteers

Colonic Diseases

Canada
PYC Therapeutics

Recruiting

SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Platypus)

Retinal Dystrophy | PRPF31 Mutationassociated Retinal Dystrophy | RP11

United States
Global Health Drug Discovery Institute
CMAX Clinical Research Pty Limited; Avance Clinical

Completed

SAD Study of APR002 Investigating the Safety/Tolerability, Pharmacokinetics/Pharmacodynamics in Healthy Subjects

COVID-19

Australia
Luye Pharma Group Ltd.

Not yet recruiting

A Phase 1, SAD Study to Evaluate the Safety and Tolerability of LY03017

Negative Symptoms of Schizophrenia | Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis | Hallucinations and Delusions Associated With Parkinson Disease Psychosis

China
Regado Biosciences, Inc.

Completed

Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD (SC101)

Healthy Volunteer

United States
Pherin Pharmaceuticals, Inc.

Completed

Intranasal PH94B for Management of the Symptoms of Generalized Social Phobia (PH94B-SAD)

Social Anxiety Disorder | Social Phobia

United States
University of Pennsylvania
Janssen Scientific Affairs, LLC

Recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
IRCCS Burlo Garofolo

Recruiting

Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion

Adnexal Torsion

Austria, Italy, Serbia
AstraZeneca

Completed

An Epidemiological Study to Describe Symptom Control and Impact of Gastroesophageal Reflux Disease

GERD

Serbia
University of Copenhagen

Completed

Trigger-point Blockade in Persistent Pain After Laparoscopical Groin Hernia Repair (Trigger-lap)

Chronic Pain

Denmark
National Institute of Mental Health (NIMH)

Completed

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning

Anxiety Disorders

United States
PYC Therapeutics

Not yet recruiting

SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

Autosomal Dominant Optic Atrophy | Kjer Optic Atrophy | OPA1 Gene Mutation | Hereditary Optic Atrophies
Athira Pharma
Fortrea Holdings, Inc.

Recruiting

A SAD and MAD Study of the Safety, Tolerability, and Pharmacokinetics of ATH-1105

Healthy Volunteers

United States
Xi'an Biocare Pharma Ltd.

Completed

A SAD/MAD Study to Evaluate the Safety, Tolerability, PK and PD of MT2004

Healthy

United States
MDI Therapeutics, Inc.

Recruiting

SAD Evaluation of Safety, Tolerability, PK, and PD of MDI-2517 in Healthy Participants

Safety and Tolerability

United States
Diceros Therapeutics
Diceros Therapeutics Australia Pty Ltd

Not yet recruiting

Phase 1, SAD/MAD of Verasone™ Administered by Sinonasal Irrigation in Healthy Participants

Healthy Volunteers

Australia
The University of The West Indies

Completed

Screening for Depression in cADiovasCular pAtients at a Tertiary Center in Trinidad. (SAD-CAT)

Depression

Trinidad and Tobago
Pherin Pharmaceuticals, Inc.

Completed

Feasibility Study of PH94B Nasal Spray for Acute Treatment of Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Merck KGaA, Darmstadt, Germany
Merck d.o.o., Serbia

Completed

A Post Marketing Assessment of Gonal f Solution for Injection in a Prefilled Pen for Follicular Stimulation in in Vitro Fertilisation/Embryo Transfer (IVF-ET) Cycles (POINT)

Infertility

Serbia
Cartiheal (2009) Ltd

Completed

Agili-CTM Implant Performance Evaluation in the Treatment of Osteoarthritis of the Great Toe

Osteoarthritis of Multiple Joints of Ankle or Foot

Italy, Slovenia, Serbia, Israel
Band Therapeutics

Completed

A SAD/MAD Study of Safety, Tolerability and Pharmacologic Activity of BT200 in Normal Volunteers

Intracranial Arteriosclerosis | Cerebrovascular Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

Austria
Autobahn Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

SAD/MAD of ABX-002-1902 Investigating the Safety, Pharmacokinetics/Pharmacodynamics of in Healthy Subjects

MDD

Australia
Shaanxi Micot Technology Limited Company

Enrolling by invitation

A SAD/MAD Study to Evaluate the Safety, Tolerability, PK of MT200605 in Healthy Subjects

Healthy

China
University of Novi Sad, Faculty of Sport and Physical...

Completed

Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise Performance

Energy Metabolism
1ST Biotherapeutics, Inc.

Not yet recruiting

A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418

Amyotrophic Lateral Sclerosis (ALS) | Parkinson Disease Psychosis
Ribon Therapeutics, Inc.

Recruiting

SAD/MAD Safety and PK Study of RBN-3143 in Healthy and Atopic Dermatitis Subjects

Atopic Dermatitis

Australia, New Zealand
University of Jaén
Histocell, S.L.; Andalusian Health Service: District Poniente Almería.; Andalusian... and other collaborators

Completed

Evaluation of the Efficacy of an Antioxidant Dressing in Chronic Wound Healing (REOX)

Hard-to-heal Wounds

Spain
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers (QPX9003)

Bacterial Infections

United States
Qilu Pharmaceutical Co., Ltd.

Completed

Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous FL058 Administered in Healthy Subjects(SAD)

Healthy

China
University of Copenhagen
Rigshospitalet, Denmark

Completed

Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair (Trigger-open)

Chronic Pain | Inguinal Hernia

Denmark
Valbiotis
Institut Pasteur de Lille; Biofortis Mérieux NutriSciences

Completed

Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes (TOTUM-63 TWO)

Obesity | Disease | Insulin Resistance | Type 2 Diabetes | Hypertriglyceridemia | Prediabetes

France, Ireland, Serbia, Slovenia
Mediar Therapeutics
ICON plc

Recruiting

A First-in-Human Safety Trial of MTX-463

Healthy

United States
Centre for Addiction and Mental Health

Completed

Transdiagnostic iCBT for Depression and Anxiety

Generalized Anxiety Disorder | Major Depressive Disorder | Social Anxiety Disorder | Panic Disorder

Canada
Shivanka Research, LLC
Eric Solutions LLC; Clinexcel Research, Ahmedabad, India

Not yet recruiting

SAD Study to Evaluate Safety, Tolerability, and Pharmacokinetic Profile of KSHN001126 in Healthy Post-Menopausal Females

Healthy Postmenopausal Women

United States, India
Chong Kun Dang Pharmaceutical

Unknown

CKD-504 in SAD and MAD in Healthy Korean and Caucasian Adult Male and Female Subjects

Huntington Disease

Korea, Republic of
Verona Pharma plc

Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Chronic Obstructive Pulmonary Disorder | Inflammatory Disorder of the Respiratory Tract

United Kingdom
AQILION AB

Completed

SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects

Eosinophilic Esophagitis (EoE)

United Kingdom

Search clinical trials for: Single ascending dose (SAD)

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