Search clinical trials for: Very high risk MDS

Total 32911 results

Baylor Research Institute

Completed

Clofarabine and Ara-C for the Treatment of Relapsed AML and Untreated MDS

Myelodysplastic Syndromes | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Weill Medical College of Cornell University

Completed

Mylotarg and Ara-C in Untreated Patients Above 60 Years With AML and High-Risk MDS

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
King's College London

Completed

Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalities

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
M.D. Anderson Cancer Center

Completed

Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
National Cancer Institute (NCI)

Completed

A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS)

Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Adult Acute Myeloid Leukemia... and other conditions

United States
TURRINI FABRIZIO

Completed

Exercise Testing to Screen for Unknown Coronary Artery Disease in Diabetic Patients: Does it Contribute to a Risk Reduction in Very High Risk Patients? (DADDY-D)

Coronary Artery Disease | Diabetes Mellitus

Italy
University Hospital Muenster
German Federal Ministry of Education and Research; Deutsche Krebshilfe e.V....

Completed

Biology and Treatment Strategy of AML in Its Subgroups: Multicenter Randomized Trial by the German Acute Myeloid Leukemia Cooperative Group (AMLCG)

Acute Myeloid Leukemia

Germany
Tel-Aviv Sourasky Medical Center

Unknown

Safety And Efficacy Of Azacitidine, and Lenalidomide In Higher Risk Myelodysplastic Syndrome (ViLen 001)

Myelodysplastic Syndrome

Israel
M.D. Anderson Cancer Center
Sanofi

Terminated

Oxaliplatin, Fludarabine, and Cytarabine in Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia

United States
M.D. Anderson Cancer Center
Genzyme, a Sanofi Company

Completed

Clofarabine vs Clofarabine in Plus With Low-Dose Ara-C in Previously Untreated Patients With Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS).

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
M.D. Anderson Cancer Center
Celgene Corporation

Completed

Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
M.D. Anderson Cancer Center
Novartis

Completed

Gleevec/Low-Dose Ara-C Study for Elderly Patients With AML and Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia, Myeloid

United States
M.D. Anderson Cancer Center
Celgene Corporation

Completed

Phase II 5-Azacytidine Plus VPA Plus ATRA

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Nordic MDS Group

Completed

Lenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5

AML | MDS

Denmark, Norway, Sweden
Nordic MDS Group

Unknown

The Efficacy of Azacitidine +/- Lenalidomide in High-risk Myelodysplastic Syndrome (MDS)and Acute Myeloid Leukemia (AML) With Del(5q).

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

Sweden
Pfizer

Completed

Open, Non Comparative Study Of Voriconazole In Slovak Patients With Very High Risk Of Developing An Invasive Fungal Infection (Ve-RIFI)

Invasive Fungal Infections
Hannover Medical School
Genzyme, a Sanofi Company

Unknown

ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS (ClAraC-SCT)

Acute Myeloid Leukemia | MDS

Germany
McNeil Consumer & Specialty Pharmaceuticals, a...
Angelini

Completed

Safety & Efficacy Study of Benzydamine Oral Rinse for the Treatment of Oral Mucositis (Mouth Sores) Resulting From Radiation Therapy for Cancer of the Oral Cavity, Oropharynx, or Nasopharynx

Stomatitis | Radiation Effects
Assistance Publique - Hôpitaux de Paris

Completed

5-azacytidine Valproic Acid and ATRA in AML and High Risk MDS

Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukaemia (AML)

France
Wolfson Medical Center

Unknown

Assessment of Labile Plasma Iron (LPI) in Myelodysplastic Syndromes (MDS) and Primary Myelofibrosis

Primary Myelofibrosis | Myelodysplastic Syndrome

Israel
Cooperative Study Group A for Hematology

Unknown

Reduced-intensity Conditioning Allogeneic Hematopoietic Cell Transplantation (RICandDLI)

Myelodysplastic Syndrome

Korea, Republic of
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome
St. Jude Children's Research Hospital

Completed

Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

Lymphoma, Non-Hodgkin | Hodgkin Disease | Chronic Myeloid Leukemia | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Myelodysplastic Syndrome (MDS) | Secondary AML | Juvenile Myelomonocytic Leukemia (JMML) | Secondary MDS

United States
Tel-Aviv Sourasky Medical Center

Unknown

Safety and Efficacy of Azacitidine, and Thalidomide in Higher Risk MDS (Myelodysplastic Syndrome) (IMDS001)

Myelodysplastic Syndrome

Israel
Groupe Francophone des Myelodysplasies

Unknown

Lenalidomide in Subjects With intermediate2 or High MDS Associated With a Deletion (DEL) 5q [31]

Myelodysplastic Syndromes

France
Shanghai Mental Health Center

Not yet recruiting

Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder

Gambling Disorder

China
King's College Hospital NHS Trust
King's College London

Not yet recruiting

ESCALATion of Medical Therapy Following Multimodality Plaque Evaluation in High-risk Chronic Coronary Syndromes (ESCALATE)

Coronary Artery Disease
Sun Yat-sen University

Not yet recruiting

Neoadjuvant HAIC and PD-1 Plus Adjuvant PD-1 for High-risk Recurrent HCC

Hepatocellular Carcinoma | Beyond Milan Criteria
Ruijin Hospital

Recruiting

A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence

Type 1 AIP

China
Nausicaa Medical
Clin-Experts

Not yet recruiting

Prevention of Pressure Ulcers in Patients at Medium to High Risk of Pressure Ulcers Using the R'GO SOINS Overlay Mattress (PRESERVE)

Pressure Ulcer

France
Minovia Therapeutics Ltd.

Recruiting

A Study to Evaluate the MNV-201 in Patients With Low Risk MDS

Myelodysplastic Syndromes

Israel
Samsung Medical Center

Recruiting

Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H) (DESAR-H)

High Risk Prostate Carcinoma

Korea, Republic of
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High Risk COPD Population (POPMIX-COPD)

Chronic Obstructive Pulmonary Disease | Multimorbidity | Population Medicine
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High-Risk COPD Smokers (POPMIX-Smoking)

Smoking Reduction | Tobacco Use Cessation | Multimorbidity
Ruijin Hospital

Not yet recruiting

The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial

MF,PMF,PPV-MF,PET-MF

China
Ruijin Hospital

Not yet recruiting

The Efficacy of Allo-HSCT in ND HR-CBF-AML

Acute Myeloid Leukemia

China
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-component Interventions on Populations With Mental Health Symptoms and High-risk COPD (POPMIX-MH)

Multimorbidity | Mental Health Issue | Multi-component Interventions
Fudan University

Recruiting

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Rectal Cancer

China
Qilu Hospital of Shandong University

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

Carcinoma, Hepatocellular

China
Dana-Farber Cancer Institute

Not yet recruiting

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

Cancer Predisposition Syndrome | Predisposition, Genetic

United States
Medtronic - MITG

Not yet recruiting

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia (RECOVER)

Hernia | Hernia, Abdominal | Hernia, Ventral | Hernia Abdominal Wall
Ohio State University
Patient-Centered Outcomes Research Institute; The George Washington University...

Not yet recruiting

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes (DECIDE)

Pregnancy, High Risk | Gestational Diabetes Mellitus

United States
Insel Gruppe AG, University Hospital Bern

Not yet recruiting

The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care

Risk Reduction | Hypobaric Hypoxia | High Altitude

Switzerland
Kardion Inc

Not yet recruiting

PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

Coronary Artery Disease
Indiana University
University of Texas; Northeastern University

Not yet recruiting

Evidence-informed Trial of Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in High-risk Pregnant Individuals

Pregnancy Complications | Gestational Diabetes

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial

Lung Carcinoma

United States
University of Leeds

Not yet recruiting

OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals (OPTIMISE)

Cardiovascular Diseases | Pulmonary Disease | Metabolic Disease | Renal Disease
Fujian Provincial Hospital

Recruiting

Impact of the Digital Multi-domain Cognitive Intervention in High-risk Populations for Dementia

Cognitive Dysfunction

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States

Search clinical trials for: Very high risk MDS

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