Search clinical trials for: miR-122 antagonist

Total 34322 results

St. Luke's-Roosevelt Hospital Center

Completed

The Efficacy of Nurse-driven, Protocol Guided Ventilator Weaning in a Medical-Surgical Intensive Care Unit (ICU)

Vent Weaning in Medical- Surgical ICUs
Allergan

Completed

BOTOX® in the Treatment of Upper Facial Lines in Japan

Glabellar Lines | Frown Lines | Crow's Feet Lines | Upper Facial Rhytides

Japan
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Completed

Vaccination of AJCC Stage IIB, IIC, III and IV Melanoma Patients With Human and Mouse Tyrosinase DNA Vaccines

Melanoma | Skin

United States
Yokohama City University Medical Center

Unknown

The Effectiveness of Two Osteoporosis Drugs on Prosthetic Bone Mineral Density (BMD) Loss After Total Hip Arthroplasty(THA) (ETOD)

Arthroplasty, Replacement, Hip | Bone Density

Japan
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of MK0966 (Rofecoxib) on the Recurrence of Colorectal Adenomas (0966-122)

Colorectal Adenoma
Assistance Publique - Hôpitaux de Paris

Recruiting

Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia. (SHARP)

Hospital-acquired Pneumonia

France
Zagazig University

Completed

miRNA-155 Assay Before and After Immunotherapy and Probiotics

Allergic Rhinitis

Egypt
Tarapeutics Science Inc.

Recruiting

A Study of HYML-122 and Cytarabine in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Relapsed or Refractory Acute Myeloid Leukemia (AML)

China
Tufts Medical Center
Immune Control

Completed

Fluphenazine Hydrochloride for Psoriasis (FP-CL2)

Psoriasis

United States
Paracelsus Medical University
Ludwig Boltzmann Institute for Digital Health and Prevention

Completed

Impact of 4 Months of Exercise Changes of Heart Health-related Epigenetic Markers in Healthy, Sedentary Individuals (miR-4-heart)

Sedentary Behavior

Austria
UCB BIOSCIENCES, Inc.
R-Pharm

Terminated

The Long-term Safety and Efficacy of CDP6038 (Olokizumab) With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Japan, Korea, Republic of, Taiwan
University of Alberta

Recruiting

The Effect of Mandibular Advancement Devices on Markers of Cardiovascular Health in Obstructive Sleep Apnea Patients

Obstructive Sleep Apnea

Canada
Dana-Farber Cancer Institute
Bristol-Myers Squibb

No longer available

Early Patient Access Single Named Patient Program for the Use of Ulocuplumab for the Treatment of Multiple Myeloma

Multiple Myeloma | Multiple Myeloma in Relapse

United States
Brian Burke, MPH

Unknown

Ozurdex With Rescue Lucentis for Treating Macular Edema Secondary to Retinal Vein Occlusion

Retinal Vein Occlusion

United States
Policlinico Universitario, Catania

Recruiting

Effects of Confortable Environment, Kangaroo Care and Music Therapy in Newborns in Neonatal Intensive Care Unit (PRE-CARE)

Newborn Morbidity | Premature Infant Disease

Italy
University Hospital Olomouc
University Hospital Ostrava; Tomas Bata Hospital, Czech Republic; General University... and other collaborators

Recruiting

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Cushing Syndrome | Pheochromocytoma | Adrenocortical Carcinoma | Adrenal Cortex Diseases | Adrenocortical Adenoma | Adrenal Tumor | Adrenalectomy; Status | Adrenal Mass | Adrenal Hyperplasia | Adrenal Disease | Adrenocortical Tumor | Conn Adenoma | Adrenal Gland Metastasis

Czechia
Samsung Medical Center

Recruiting

Physiologic Assessment of Microvascular Function in Patients With Cardiac Amyloidosis

Cardiac Amyloidosis

Korea, Republic of
Samsung Medical Center

Completed

Effect of Simultaneous Dual Stimulation on Freezing of Gait in Parkinson's Disease

Parkinson Disease
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
China Medical University Hospital

Completed

Clinical Investigation on the Treatment of Radiation Induced Dermatitis With Radiation Care® Gel

Radiation Dermatitis

Taiwan
Dar El Oyoun Hospital
Cairo University

Completed

Focal Laser Single Intravitreal Ranibizumab Retinal Artery Macroaneurysm. (RAM)

Retinal Artery Macroaneurysm

Egypt
CinDome Pharma, Inc.

Terminated

A Scintigraphy Study in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Samsung Medical Center

Terminated

Trial of AZD5363 Plus Paclitaxel /AZD2014 Plus Paclitaxel in Biomarker Negative (PIK3CA/MEK/RAS/TP53/MET) Gastric Adenocarcinoma Patients as Second-line Chemotherapy

Advanced Gastric Adenocarcinoma

Korea, Republic of
GE Healthcare
Quintiles, Inc.; H2O Clinical LLC

Completed

Phase 4 Study to Demonstrate Prognostic Usefulness of AdreView™ Scintigraphy for Identifying Subjects With Heart Failure Who Will Experience Death During 60 Months Follow-up.

Heart Failure (HF)

United States
GE Healthcare
Quintiles, Inc.; H2O Clinical LLC

Completed

Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.

Ventricular Dysfunction, Left | Heart Failure (HF)

United States
VA Office of Research and Development

Completed

Enhancing Delivery of Problem Solving Therapy Using SmartPhone Technology

Depression | Anxiety

United States
China Medical University Hospital

Unknown

Evaluate the Efficacy of Bu-Yang- Huan-Wu Tang（BYHWT）on Ischemic Stroke

Ischemic Stroke

Taiwan
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Divalproex Sodium ER Tablets 500 mg of Dr. Reddy's Under Fasting Conditions

Healthy

India
University of Oulu
Tampere University

Completed

Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care

Respiration

Finland
Bayside Health
Deakin University

Completed

Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia

Pneumonia, Ventilator Associated | Closed System Suction Catheter

Australia
Morphotek

Terminated

An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer (FAR-122)

Ovarian Cancer

Canada, United States, Netherlands, Spain, Belgium, Australia
Cairo University

Not yet recruiting

Accuracy of Upper Lip Bite Test and Measurement of Skin-to-epiglottis Distance in Predicting Difficult Laryngoscopy: a Prospective Observational Study

Difficult Laryngoscopy | Upper Lip Bite Test
Sirnaomics

Recruiting

Single Ascending Dose of FXI-GalNAc-siRNA in Healthy Subjects

FXI

United States, Canada
China Medical University Hospital

Recruiting

The Roles of Vitamin D and Microbiome in Children With Post-acute COVID-19 Syndromes (PACS) and Long COVID

Post-acute COVID-19 Syndromes

Taiwan
89bio, Inc.

Active, not recruiting

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH) (ENLIVEN)

NASH - Nonalcoholic Steatohepatitis

United States, Puerto Rico
Cairo University

Completed

The Ability of Perfusion Index and Positional Perfusion Index Variation to Predict Spinal Anesthesia-induced Hypotension in Elderly Patients

Spinal Anesthesia Induced Hypotension

Egypt
Mayne Pharma International Pty Ltd

Completed

Adrenal Suppression and Absorption Study of Halobetasol Propionate Foam in Subjects 12-17 With Plaque Psoriasis

Plaque Psoriasis

United States, Poland, Ukraine, Georgia
Scynexis, Inc.

Completed

ADME Study of [14^C]-Ibrexafungerp in Healthy Male Subjects

Fungal Disease

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Measure Daridorexant in Breast Milk of Healthy Lactating Women

Healthy

United States
Portsmouth Hospitals NHS Trust
University of Portsmouth; NxStage Medical

Completed

FREquent DIalysis & Markers of Cardiac Strain and Injury, Physical Fitness, Habitual Physical Activity & Quality of Life (FREDI-CAL)

Kidney Failure

United Kingdom
Genfit

Completed

Nitazoxanide Pharmacokinetic Parameters in Renal Impaired Subjects

Renal Impairment | Kidney Disease | Renal Disease

United States
VA Ann Arbor Healthcare System

Completed

Low-Carbohydrate Diabetes Prevention Program Among Veterans With Prediabetes (VA LC-DPP)

PreDiabetes

United States
Purdue University
Grain processing corporation

Completed

The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans

Type2 Diabetes | Postprandial Hyperglycemia | Blood Sugar; High

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of an HIV Vaccine (gp145 C.6980) in Healthy, HIV-Uninfected Adults in the United States

HIV Infections

United States
Minia University

Unknown

Comparison Between Single Shot Ultrasonographic Guided Fascia Iliaca Block and Quadratus Lumborum Block in Hip Arthralgia. Comparative Double Blind Study

Analgesia
Vertex Pharmaceuticals Incorporated

Completed

A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric Patients

Cystic Fibrosis
Amer Zureikat
National Institutes of Health (NIH)

Completed

Study of Pre-surgery Gemcitabine + Hydroxychloroquine (GcHc) in Stage IIb or III Adenocarcinoma of the Pancreas

Pancreatic Cancer

United States
Pontificia Universidad Catolica de Chile

Completed

Effect of the Consumption of Burgers Prepared With Wine Grape Pomace Flour, on Components of the Metabolic Syndrome (WGPF-burger)

Metabolic Syndrome | Food Selection
Bial - Portela C S.A.

Completed

An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites

Parkinson's Disease (PD)

Netherlands
Astrid Crespo

Completed

E-nose and Inflammatory Asthma Phenotypes

Persistent Asthma

Spain

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