Search clinical trials for: topical treatment

Total 65507 results

Montefiore Medical Center

Withdrawn

Thulium Laser and Topical Platelet Rich Plasma (PRP) vs. PRP Injection for the Treatment of Male Androgenetic Alopecia

Androgenetic Alopecia
Zagazig University

Completed

Evaluation of Efficacy of Topical Flutamide in the Treatment of Acne Vulgaris

Acne Vulgaris Superficial Mixed Comedonal and Inflammatory

Egypt
GTO Pharmaceutical, LLC

Terminated

Sexual Penetration Pain in Postmenopausal Women: A Topical Botanical Drug Treatment

Female Sexual Dysfunction | Vulvovaginal Atrophy | Vulvodynia | Dyspareunia | Vestibulodynia | Postmenopausal Symptoms | Arousal Disorders, Sexual | Genito-Pelvic Pain/Penetration Disorder | Female Sexual Arousal Disorder | Sexual Pain Disorders

United States
Aalborg University

Completed

Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptor

Itch

Denmark
Pfizer

Completed

Study of Abrocitinib Compared With Dupilumab in Adults With Moderate to Severe Atopic Dermatitis on Background Topical Therapy

Atopic Dermatitis

Spain, Taiwan, United States, Korea, Republic of, Poland, Canada, Australia, Hungary, Germany, Latvia, Finland, Chile, Bulgaria, Slovakia, Italy
Pfizer

Completed

Dose Ranging Study To Assess Efficacy, Safety and Tolerability Of PF-06700841 Topical Cream In Psoriasis

Psoriasis

United States, Germany, Canada, Denmark, Hungary, Australia, Latvia, Poland, Bulgaria, Japan
Massachusetts General Hospital

Terminated

DAA Treatment in Donor HCV-positive to Recipient HCV-negative Heart Transplant

Hepatitis C | End Stage Heart Disease

United States
University of Monastir

Completed

Topical Piroxicam vs Soulagel in the Treatment of Acute Extremity Pain After Emergency Department Discharge (TPS)

Acute Pain

Tunisia
Universidad de Antioquia
INNOVATION CORPORATION FOR THE DEVELOPMENT OF PRODUCTS FOR TROPICAL DISEASES... and other collaborators

Withdrawn

Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis. (Curaleish)

Leishmaniasis, Cutaneous

Colombia
University of Wisconsin, Madison

Completed

Blue Light Therapy of C. Acnes

Acne

United States
Eli Lilly and Company
Dermira, Inc.

Completed

Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis. (ADhere)

Atopic Dermatitis

United States, Canada, Germany, Poland
Sheba Medical Center

Completed

Corticosteroids+5-aminosalicylic Acid Compared to Corticosteroids in the Treatment of Moderate-severe Ulcerative Colitis

Ulcerative Colitis

Israel, China, France, Greece, Italy, Korea, Republic of, Serbia
Combined Military Hospital Abbottabad

Completed

Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies

Scabies

Pakistan
Massachusetts Eye and Ear Infirmary

Completed

Topical Avastin for Treatment of Corneal Neovascularization

Corneal Neovascularization

United States
TWi Biotechnology, Inc.

Completed

Prophylactic Treatment of Skin Rash Associated With EGFR Inhibitor Therapy

EGFR Inhibitor-Induced Skin Rash

Taiwan
Soligenix

Completed

FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides)

Cutaneous T-Cell Lymphoma

United States
Krankenhaus Barmherzige Schwestern Linz
Medical University of Vienna

Completed

TRICIN: Prospective Study on the Efficacy of Single Topical Trichloroacetic Acid (TCA) 85% in the Treatment of Cervical Intraepithelial Neoplasia (CIN 1/2) (TRICIN)

Cervical Intraepithelial Neoplasia Grade 1 | Cervical Intraepithelial Neoplasia Grade 2

Austria
Tufts Medical Center

Completed

The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED

Dry Eye Disease

United States
University of Campinas, Brazil
Texas Tech University

Completed

Microneedle Pretreatment as a Strategy to Improve the Effectiveness of Topical Anesthetics Formulations

Oral Cavity Disease

Brazil
Taro Pharmaceuticals USA

Completed

A Study Comparing Halobetasol Propionate and Tazarotene Topical Lotion 0.01%/0.045% to Duobrii® Lotion (Halobetasol Propionate and Tazarotene Lotion), 0.01%/0.045% (Reference Listed Drug) in the Treatment of Moderate to Severe Plaque Psoriasis.

Plaque Psoriasis

United States
Amgen

Completed

Study to Evaluate Safety and Effectiveness of Oral Apremilast (CC-10004) in Patients With Moderate to Severe Plaque Psoriasis (ESTEEM 1)

Plaque Psoriasis
Soroka University Medical Center

Completed

Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis

Leishmaniasis

Israel
Futura Medical Developments Ltd.

Completed

Clinical Trial Using Topically Applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction

Erectile Dysfunction

Latvia, Bulgaria, Czechia, Georgia, Hungary, Poland, Russian Federation, Slovakia, Ukraine
Henry Ford Health System
Microdermis Corporation

Completed

An Investigation Into the Efficacy of Provodine Topical Cream as Compared to 10% Benzoyl Peroxide Wash for the Treatment of Hidradenitis Suppurativa.

Hidradenitis Suppurativa

United States
Odense University Hospital

Completed

Tacrolimus as Treatment of Breast Cancer-Related Lymphedema

Breast Cancer Lymphedema

Denmark
University of Alabama at Birmingham
DUSA Pharmaceuticals, Inc.

Completed

Blue Light Photodynamic Therapy Treatment for Distal and Lateral Subungual Toenail Onychomycosis

Toenail Onychomycosis | Distal and Lateral Subungual Toenail Onychomycosis

United States
Coegin Pharma AB
Bispebjerg Hospital; Studies&Me

Active, not recruiting

Phase I/IIa Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult Subjects With AK (COAKS)

Actinic Keratoses

Denmark
Aponia Laboratories, Inc.

Completed

Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS

Pain, Acute

United States
Vyne Therapeutics Inc.

Completed

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Acne Vulgaris

United States, Dominican Republic
Vyne Therapeutics Inc.

Completed

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Acne Vulgaris

United States, Dominican Republic
Vyne Therapeutics Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris

Acne Vulgaris

United States
Vyne Therapeutics Inc.

Completed

A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea

Papulopustular Rosacea

United States
Noven Pharmaceuticals, Inc.

Completed

A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis (HP-5000)

Osteoarthritis of the Knee

United States
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Leber's Hereditary Optic Neuropathy

United States
Inotec AMD Limited
SerenaGroup, Inc.

Completed

The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers

Surgical Wound | Diabetic Foot Ulcer

United States, Puerto Rico
Chandan K Sen

Terminated

Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars

Scar

United States
Padagis LLC

Completed

Bioequivalence Study of Two Treatments in the Treatment of Acne Vulgaris on the Face

Acne Vulgaris

United States
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche

Completed

A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women

HIV Infections | Cervix, Dysplasia

United States, Puerto Rico
Center for Biomedical Research, Inc.

Completed

Topical Vitamin C for Treatment of Basal Cell Cancer

Basal Cell Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical Trifluridine

HIV Infections | Herpes Simplex

United States
Northwestern University

Completed

Topical Sildenafil as Pre-Treatment for Hand-Foot Skin Reaction

Hand Foot Skin Reaction

United States
Padagis LLC

Completed

Safety and Equivalence of a Generic Ciclopirox Olamine Topical Suspension Compared to the Reference Ciclopirox Topical Suspension 0.77% for the Treatment of Tinea Pedis

Tinea Pedis
Padagis LLC

Completed

Comparative Safety and Efficacy of Two Rosacea Products in the Treatment of Facial Erythema of Rosacea

Rosacea
Padagis LLC

Completed

A Study to Compare Clindamycin Phosphate and Benzoyl Peroxide Topical Gel 1.2%/2.5% to Acanya® Topical Gel in the Treatment of Acne Vulgaris

Acne
Terence J. Coderre
The Louise And Alan Edwards Foundation

Terminated

The Effects of Topical Treatment With Clonidine + Pentoxifylline in Patients With Neuropathic Pain (TTNP)

Neuralgia Peripheral

Canada
Verrica Pharmaceuticals Inc.
BioClinica, Inc.; Paidion Research, Inc.; Instat Consulting, Inc.

Completed

A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts (CARE-1)

Skin Diseases | Sexually Transmitted Diseases, Viral | Sexually Transmitted Diseases | Skin Diseases, Infectious | Warts | Papillomavirus Infections | Skin Diseases, Viral | Condylomata Acuminata

United States
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) (SPIFD-101)

Fuchs' Corneal Endothelial Dystrophy (FCED)

United States
Krystal Biotech, Inc.

Active, not recruiting

Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)

TGM-1 Related Autosomal Recessive Congenital Ichthyosis

United States
Sohag University

Completed

Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography AS-OCT After Topical Combined Antibiotics and Steroids Treatment in Cases of Inflammatory Punctual Stenosis

Ophthalmopathy , Lacrimal System

Egypt
Krystal Biotech, Inc.

Active, not recruiting

Topical Beremagene Geperpavec (KB103) Gene Therapy to Restore Functional Collagen VII for the Treatment of Dystrophic Epidermolysis Bullosa (GEM-1)

Dystrophic Epidermolysis Bullosa

United States

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