Search clinical trials for: VB-111

Total 3295 results

Bioray Laboratories
Xiangya Hospital of Central South University; First Affiliated Hospital of... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

China
Dynavax Technologies Corporation
Merck Sharp & Dohme LLC

Terminated

A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Metastatic Melanoma | Head Neck Cancer

United States, Germany, New Zealand, Australia
Bausch Health Americas, Inc.
Dow Pharmaceutical Sciences

Completed

Safety and Efficacy of IDP 118 in the Treatment of Plaque Psoriasis

Plaque Psoriasis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Sotatercept in Treating Patients With Myeloproliferative Neoplasm-Associated Myelofibrosis or Anemia

Anemia | Myelofibrosis | Myelodysplastic/Myeloproliferative Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Kythera Biopharmaceuticals

Completed

Open-Label Pharmacokinetic Study of Final Formulations of ATX-101

Healthy

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Metformin Hydrochloride in Mitigating Side Effects of Radioactive Iodine Treatment in Patients With Differentiated Thyroid Cancer

Thyroid

United States
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Enrolling by invitation

Imaging Inflammation in Alzheimer's Disease

Alzheimer's Disease

United States
Vanderbilt University Medical Center

Recruiting

Quantitative Imaging of Brain Glymphatic Function in Humans

Parkinson Disease

United States
Gilead Sciences
German CLL Study Group

Completed

Study to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib and Idelalisib With and Without Obinutuzumab in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

Germany
Gilead Sciences

Terminated

A Study of Idelalisib and Rituximab in Elderly Patients With Untreated CLL or SLL

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL)

United States
PegBio Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-119 Injection in Chinese Obese Subjects

Obesity
Johns Hopkins University
Radiological Society of North America

Recruiting

Long COVID-19 [11C]CPPC Study

COVID Long-Haul

United States
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
Applied Biology, Inc.
Hinova Pharmaceuticals Inc.

Not yet recruiting

HC-1119 Adjuvant Treatment for Hospitalized COVID-19 Patients

COVID-19 Respiratory Infection
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Depression

United States
Robert Fox
Case Western Reserve University

Not yet recruiting

Study Evaluating the Safety of Myeliviz Myelin-Targeting PET Agent

Healthy

United States
Bausch Health Americas, Inc.

Recruiting

A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis

Psoriasis

United States, Panama
QurAlis Corporation

Completed

A Study Evaluating Safety, Tolerability, and Pharmacokinetics of QRL-101 in Healthy Participants

Healthy Volunteers

Netherlands
Aptabio Therapeutics, Inc.
Covance

Terminated

A Phase 2 Study of APX-115 in Hospitalized Patients With Confirmed Mild to Moderate COVID-19.

COVID-19

United States
Veloxis Pharmaceuticals

Completed

A Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VEL-101

Healthy Volunteers

United States
Amgen

Terminated

Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity

Obesity

United States
argenx

Completed

A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness. (ADAPT+)

Generalized Myasthenia Gravis

United States, Belgium, Canada, Czechia, Denmark, France, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Serbia
Stealth BioTherapeutics Inc.

Available

An Intermediate Size Expanded Access Protocol of Elamipretide

Mitochondrial Diseases | Barth Syndrome
Merck Sharp & Dohme LLC

Completed

[11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)

Alzheimer's Disease
argenx

Approved for marketing

Efgartigimod Expanded Access for Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

United States
Hoffmann-La Roche

Completed

A Phase 1b Study of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF) (PRM151F-12GL)

Idiopathic Pulmonary Fibrosis

United States, Netherlands
Inversago Pharma Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Single Ascending Oral Doses of INV-101 in Healthy Male and Female Subjects

Pharmacokinetic

Canada
Alkermes, Inc.
University Medical Center Groningen; Amsterdam UMC, location VUmc; QPS Netherlands...

Completed

A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density

Healthy | Alzheimer Disease

Netherlands
Acanthas Pharma Inc

Withdrawn

A Study of Single Ascending Doses of STAR-101 in Healthy Participants

Healthy Volunteers
InQpharm Group

Withdrawn

Tolerability and Benefit of IQP-AS-121 on Fatigue and Mental Alertness

Fatigue

Germany
Alpine Immune Sciences, Inc.
Clinical Network Services (CNS) Pty Ltd

Completed

Adult Healthy Volunteers Study to Evaluate ALPN-101 Safety

Healthy Volunteers

Australia
Viamet

Completed

A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Moderate - Severe Interdigital Tinea Pedis

Tinea Pedis

United States
argenx

Completed

IV Dose Study to Assess the Safety, Tolerability, PK, PD and Immunogenicity of ARGX-113 in Healthy Volunteers

Healthy Volunteers
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain Amyloid Using [11C]MeS-IMPY

Healthy | Alzheimer's Disease

United States
PegBio Co., Ltd.

Completed

Continuous Multiple Dose PB-119 Injection in Health Volunteers

Type2 Diabetes Mellitus

China
Motus Therapeutics, Inc.

Completed

Phase 2 Pilot Study to Evaluate the Safety and Efficacy of RM-131 Administered to Females With Anorexia Nervosa

Anorexia Nervosa

United States
Motus Therapeutics, Inc.

Completed

Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis

Gastroparesis | Gastrointestinal Motility Disorder | Diabetes Mellitus Complications | Diabetes Mellitus Type 1 and 2

United States
Arava Bio Tech Ltd.

Unknown

Safety and Efficacy of Topical AR/101 Compared With Placebo, in Accelerating Granulation Tissue Formation of Hard-to-heal Wounds

Wounds | Other Ulcers Wounds and Skin Problems

Israel
Janssen Research & Development, LLC
Hoffmann-La Roche

Terminated

Safety and Efficacy of EVT 101 in Treatment-Resistant Depression

Depression

United States
Stealth BioTherapeutics Inc.

Withdrawn

A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure

Heart Failure

Bulgaria
Minerva Neurosciences

Completed

Pharmacokinetic Study of MIN-101 in Healthy Subjects

Schizophrenia

United Kingdom
Alaunos Therapeutics

Unknown

A Phase II Trial of ZIO-101 in Advanced Multiple Myeloma: Protocol SGL2001b

Multiple Myeloma

United States
Alaunos Therapeutics

Unknown

A Phase-II Trial of ZIO 101 in Advanced Hepatocellular Carcinoma

HEPATOCELLULAR CARCINOMA

United States
Cardiometabolics

Completed

A Clinical Trial in Higher Risk Geriatric Patients Undergoing OHSP (MiniMetrxics)

Heart Disease

Canada
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Forge Biologics, Inc

Not yet recruiting

Long-term Follow-up Study to Evaluate Safety and Efficacy of FBX-101 in Krabbe Patients

Krabbe Disease
University of Colorado, Denver
Tvardi Therapeutics, Incorporated

Recruiting

Trial of Radiotherapy in Combination With TTI-101 in Patients With Borderline Resectable Pancreatic Cancer

Pancreatic Cancer

United States
IDP Discovery Pharma S.L.

Recruiting

A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies (CASSANDRA)

Chronic Lymphocytic Leukemia (CLL) | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Multiple Myeloma (MM) | High Grade B-Cell Lymphoma, Not Otherwise Specified | Double Hit Lymphoma | Triple Hit Lymphoma

Spain

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