Clinical Trials Sponsored by Effector Therapeutics

Total 6339 results

Sangamo Therapeutics

Completed

Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART

Human Immunodeficiency Virus (HIV)

United States
Blade Therapeutics

Withdrawn

Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
Cristal Therapeutics

Completed

Efficacy Study of CPC634 (CriPec® Docetaxel) in Platinum Resistant Ovarian Cancer (CINOVA)

Cancer | Ovarian Cancer

Netherlands, Belgium, United Kingdom
Amicus Therapeutics

Completed

Open-Label Extension Study of the Long-Term Effects of Migalastat HCL in Patients With Fabry Disease

Fabry Disease

United States, Austria, United Kingdom, Argentina, Australia, Belgium, Brazil, Canada, Denmark, Egypt, France, Italy, Japan, Spain, Turkey
PTC Therapeutics

Completed

Study of Ataluren for Previously Treated Participants With Nonsense Mutation Duchenne/Becker Muscular Dystrophy (nmDBMD) in Europe, Israel, Australia, and Canada

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dystrophinopathy

United Kingdom, Canada, Germany, Spain, Sweden, Italy, Australia, Belgium, France, Israel
Arthrosi Therapeutics

Completed

The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males

Healthy Volunteers

Australia
Symbiomix Therapeutics

Completed

A Phase 2 Study of SYM-1219 to Treat Bacterial Vaginosis

Bacterial Vaginosis

United States
United Therapeutics

Terminated

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

Pulmonary Hypertension | Heart Failure With Preserved Ejection Fraction

United States
AKARI Therapeutics

Completed

Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576 (CAPSTONE)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Kazakhstan, Lithuania, Sri Lanka
Blade Therapeutics

Withdrawn

Healthy Volunteer Study Comparing Tablet and Capsule Formulations

Fibrosis

Australia
Trevi Therapeutics

Completed

Open Label Extension Study of Nalbuphine HCl ER in Patients With Prurigo Nodularis

Prurigo Nodularis | Prurigo | Nodularis Prurigo

Germany
Shield Therapeutics

Completed

Feraccru® Real World Effectiveness Study in Hospital Practice ( FRESH ) (FRESH)

Inflammatory Bowel Diseases | Anemia, Iron Deficiency

United Kingdom
United Therapeutics

Terminated

Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF

Pulmonary Hypertension Associated With HFpEF

United States
Promethera Therapeutics

Completed

Safety and Tolerability of HepaStem in Patients With Cirrhotic and Pre-cirrhotic NASH Patients (PANASH)

NASH - Nonalcoholic Steatohepatitis

Spain, Belgium, Bulgaria, France
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Cyclerion Therapeutics

Completed

Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension

Hypertension | Diabetes Mellitus, Type 2

United States
PTC Therapeutics

Completed

Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia

Friedreich's Ataxia

United States
Aquestive Therapeutics

Completed

Diazepam Buccal Film (DBF) - Diastat Rectal Gel (DRG) Crossover Study

Epilepsy

United States
Sage Therapeutics

Withdrawn

A Study to Evaluate Multimodal Neuroimaging Parameters in Women With Postpartum Depression Who Are Receiving ZULRESSO™ (Brexanolone)

Postpartum Depression
Aquestive Therapeutics

Completed

Three-way Crossover Study Comparing Ondansetron ODFS Administered With and Without Water to Zofran ODT Without Water

Healthy Participants
Therapeutics, Inc.

Completed

A Study of the Safety and Efficacy of UHE-105 Shampoo in Subjects With Scalp Psoriasis

Scalp Psoriasis

United States
PTC Therapeutics

Completed

Safety and Efficacy of Ataluren (PTC124) for Cystic Fibrosis

Cystic Fibrosis

Israel
Agile Therapeutics

Completed

Efficacy, Safety and Tolerability Study of Agile AG200-15 Transdermal Contraceptive Delivery System

Healthy
Balance Therapeutics

Unknown

A Study of Oral BTD-001 in Adults With Idiopathic Hypersomnia (ARISE2)

Idiopathic Hypersomnia

United States
Corcept Therapeutics

Completed

The Effect of CORT118335 on Olanzapine-Induced Weight Gain

Antipsychotic-induced Weight Gain

United Kingdom
PTC Therapeutics

Terminated

Extension Study of Ataluren in Participants With Nonsense Mutation Cystic Fibrosis

Cystic Fibrosis

United States, Spain, France, Belgium, United Kingdom, Australia, Brazil, Bulgaria, Canada, Germany, Israel, Italy, Netherlands, Poland, Argentina, Greece
Cyclerion Therapeutics

Completed

A Phase 2 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Stable Type 2 Diabetes and Hypertension

Hypertension | Diabetes Mellitus, Type 2

United States
PTC Therapeutics

Terminated

Study of Ataluren (PTC124) in Cystic Fibrosis

Cystic Fibrosis

United States, France, Spain, Belgium, Israel, Italy, Sweden
Prexton Therapeutics

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of PXT002331 (Foliglurax) in Reducing Motor Complications of Levodopa Therapy in Parkinson Disease's Patients (AMBLED)

Parkinson Disease

France, Italy, Spain, Germany, United Kingdom, Austria
MC2 Therapeutics

Completed

Evaluation of Potential Development of Photoallergic Skin Reaction After Use of MC2-01 Cream

Photoallergy

United States
PTC Therapeutics

Completed

A Study of Ataluren in Pediatric Participants With Cystic Fibrosis

Cystic Fibrosis

France, Belgium
Pendulum Therapeutics

Completed

Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Aerpio Therapeutics

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Stayble Therapeutics

Completed

A Single Ascending Dose Study of Safety and Tolerability of STA363 Compared to Placebo in 15 Patients With Chronic Discogenic Low Back Pain

Low Back Pain

Sweden
Celldex Therapeutics

Completed

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma (ReACT)

Glioblastoma | Gliosarcoma | Recurrent Glioblastoma | Small Cell Glioblastoma | Giant Cell Glioblastoma | Glioblastoma With Oligodendroglial Component | Relapsed Glioblastoma

United States
Halozyme Therapeutics

Terminated

Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma, Extrahepatic | Cholangiocarcinoma, Intrahepatic | Gallbladder Adenocarcinoma

United States, Korea, Republic of, Thailand
Entasis Therapeutics

Completed

Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections

Acute Pyelonephritis | Complicated Urinary Tract Infection

Bulgaria
MC2 Therapeutics

Completed

Evaluation of the Vasoconstriction Properties of MC2-01 Cream

Vasoconstriction

France
Atacama Therapeutics

Completed

Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States
Centrexion Therapeutics

Completed

A Study to Evaluate the Safety and Pharmacokinetics of CNTX-6016 in Healthy Subjects

Pain | Chronic Pain | Nociceptive Pain

United States
MC2 Therapeutics

Completed

A Clinical Trial Evaluating Efficacy and Safety of MC2-01 Cream

Psoriasis Vulgaris

United States
PTC Therapeutics

Withdrawn

A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia

Aniridia
Heron Therapeutics

Completed

Extended Delivery of Bupivacaine Study in Herniorrhaphy

Analgesia

United States
Cytori Therapeutics

Suspended

Safety and Feasibility of ADRCs Treatment To Patients With Thermal Wounds

Thermal Burn

United States
Celldex Therapeutics

Terminated

A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced Melanoma

Melanoma

United States
Entasis Therapeutics

Completed

Study to Determine the Excretion and Metabolism of 14C-ETX2514 Administered Intravenously in Healthy Male Subjects

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
Aptevo Therapeutics

Completed

Study of ES414 in Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer

United States, Australia
Acorda Therapeutics

Completed

Twelve Month Safety and Efficacy Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Poland, Spain
Proteon Therapeutics

Completed

A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2)

Chronic Kidney Disease

United States, Canada
Corcept Therapeutics

Terminated

Retrospective Chart Review Study of Pediatric Patients Treated With Korlym for Cushing Syndrome

Cushing Syndrome | Hypercortisolism

United States

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