Clinical Trials Sponsored by Instituto Carlos III

Total 920 results

Fundació Institut de Recerca de l'Hospital de la...
Carlos III Health Institute; Spanish Clinical Research Network - SCReN

Completed

Randomizated Open-label Control Trial to Evaluate if the Incorporation of sFlt1/PlGF Ratio in the Diagnosis and Classification of PE Improves Maternal and Perinatal Outcomes in Women With the Suspicion of the Disease (EuroPE)

Preeclampsia

Spain
Anna Baiges
Hospital Universitario Ramon y Cajal; Instituto de Salud Carlos III; Gregorio...

Recruiting

Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy

Hepatic Encephalopathy | Sarcopenia | Cirrhosis, Liver

Spain
Universitat Jaume I
Instituto de Salud Carlos III; Conselleria de Innovación, Universidades, Ciencia...

Recruiting

Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care

Depressive Disorder | Depression | Depressive Symptoms

Spain
Fundación para el Fomento de la Investigación Sanitaria...
Instituto de Salud Carlos III

Completed

Periodontal Status and Endothelial Dysfunction in Patients With Polycystic Ovary Syndrome

Periodontal Diseases

Spain
Universidad de Granada
Instituto de Salud Carlos III; Hospital Clinico Universitario San Cecilio; University...

Unknown

Activating Brown Adipose Tissue Through Exercise (ACTIBATE)

Obesity | Diabetes Mellitus | Metabolic Syndrome X

Spain
Fundació Institut de Recerca de l'Hospital de la...
Carlos III Health Institute; Spanish Clinical Research Network - SCReN

Completed

Clinical Trial in Antiaggregated Patients With Proximal Femur Fracture Evaluating a Strategy to Shorten Time Until Surgery (AFFEcT)

Femur Fracture

Spain
Institute of Technology, Carlow

Unknown

The Effects of Exercise on Behavior and Fitness in Children With ASD

Autism Spectrum Disorder | Behavior

Ireland
Hospital Universitari Vall d'Hebron Research Institute
Instituto de Salud Carlos III; Universidade Mandume Ya Ndemufayo; Fundo de Apoio... and other collaborators

Active, not recruiting

Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two Provinces in Southern Angola, Huíla and Cunene.

Malnutrition, Child

Angola
Institute of Technology, Carlow

Active, not recruiting

The Effects of Covid-19 Pandemic on the Cardiovascular Heath of Children With Autism Spectrum Disorder (ASD)

Autism Spectrum Disorder | Cardiovascular Health

Ireland
Institute of Technology, Carlow

Completed

Treatment Time-frame Guideline for Dry Needling in the Lower Limb

Trigger Points

Ireland
Institut Català d'Oncologia
Fundación Sociedad Española de Oncologia Médica; Instituto de Salud Carlos III and other collaborators

Recruiting

Early On-treatment Transcriptional Profiling as Predictor of Response in Early-stage HER2-positive Breast Cancer (BiOnHER)

Neoplasms | Breast Cancer | HER2-positive Breast Cancer

Spain
Fundacion para la Investigacion y Formacion en...
Carlos III Health Institute; Castilla-León Health Service

Completed

Blood Pressure and Subclinical Organ Damage (Vasorisk)

Diabetes Mellitus

Spain
Instituto de Investigacion Sanitaria La Fe
Instituto de Salud Carlos III; Hospital Universitario La Fe; Spanish Agency of...

Recruiting

Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression (EMTtfNI)

Bipolar Depression | Resistant Depression, Treatment

Spain
Instituto de Ciencia y Tecnología de Alimentos...
Instituto de Salud Carlos III; Puerta de Hierro University Hospital; Comunidad...

Completed

Bioavailability of Carotenoids From Orange Juice in a Cross-over Study in Healthy Subjects.

Biological Availability | Carotenoids | Humans | Lutein

Spain
Instituto de Investigacion Sanitaria La Fe
Sociedad Española de Neumología y Cirugía Torácica; Sociedad Valenciana de... and other collaborators

Recruiting

Duration of Antibiotic Treatment in Community-acquired Pneumonia (ADAPT)

Community-acquired Pneumonia

Spain
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; IVI Madrid; Fundación IVI

Completed

Biochemical Pregnancy Loss. A Multicenter Retrospective Study (BPL)

Pregnancy Loss, Early

Spain
Fundación Pública Andaluza Progreso y Salud
Instituto de Salud Carlos III

Unknown

Clinical Trial to Evaluate the Efficacy of Treatment vs Discontinuation in a First Episode of Non-affective Psychosis (NONSTOP)

Psychosis Nos/Other

Spain
Fundación Instituto de Estudios de Ciencias de...
Instituto de Investigación Biomédica de Salamanca; Instituto de Salud Carlos...

Recruiting

Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) (CARTIER)

Elderly | Cardiotoxicity | Antineoplastic Agents | Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

Spain
IVI Sevilla
Instituto Valenciano de Infertilidad, IVI VALENCIA; IVI Madrid; IVI Barcelona

Enrolling by invitation

Detection of Kisspeptins and miRNAs in Patients With Non-viable Pregnancy (TESTKM)

Non-Viable Pregnancy

Spain
IVI Sevilla
Instituto Valenciano de Infertilidad, IVI VALENCIA; IVI Madrid; IVI Barcelona

Terminated

Corifollitropin Alfa Versus Daily rFSH in the Controlled Ovarian Stimulation of Poor Responders (MANCOR)

Infertility

Spain
Puerta de Hierro University Hospital
Instituto de Salud Carlos III; Ministerio de Economía y Competitividad, Spain; Gammera Nest Technology Company

Unknown

The Secret Trail of Moon (Serious Videogame) and Chess on ADHD: a Clinal Trial

Attention Deficit Disorder With Hyperactivity

Spain
The Mediterranean Institute for the Advance of...
Carlos III Health Institute; Preventive Services and Health Promotion Research...

Completed

Effectiveness of the "7H" Intervention to Reduce Frequent Attendance in Primary Care ("7H")

Frequent Attenders

Spain
Hospital Clinic of Barcelona
Instituto de Salud Carlos III; Institut d'Investigacions Biomèdiques August... and other collaborators

Recruiting

Enhancing Cognitive Reserve of the Offsprings of Bipolar and Schizophrenic Patients

Bipolar and Related Disorders

Spain
Sara V. Latorre
Instituto de Salud Carlos III; Fondos ARI (Assistencia Recerca Intensiva); Fondo...

Active, not recruiting

Clinical Trial Using Humanized CART Directed Against BCMA (ARI0002h) in Patients With Relapsed/Refractory Multiple Myeloma to Proteasome Inhibitors, Immunomodulators and Anti-CD38 Antibody.

Relapsed/Refractory Multiple Myeloma

Spain
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS); Carlos III... and other collaborators

Completed

NVD in Hypothermic HIE Neonates

HIE - Perinatal Hypoxic - Ischemic Encephalopathy
Servicio Canario de Salud
Instituto de Salud Carlos III; Asociación para la Diabetes de Tenerife; Asociación...

Completed

Tertiary Prevention in Type II Diabetes Mellitus in Canary Islands Study (INDICA)

Type 2 Diabetes Mellitus

Spain
III. Medizinische Klinik Mannheim

Unknown

Chemotherapy and Biological Therapy With or Without Bone Marrow or Peripheral Stem Cell Transplant in Treating Patients With Chronic Myelogenous Leukemia

Leukemia

Switzerland, Germany, Spain, Poland, Czech Republic
Red de Terapia Celular
Castilla-León Health Service; Instituto de Salud Carlos III; University of Valladolid and other collaborators

Completed

Treatment of Severe COVID-19 Pneumonia With Allogeneic Mesenchymal Stem Cells (MSV-COVID)

COVID-19 Pneumonia

Spain
Enrique de-Madaria
Instituto de Salud Carlos III; Asociación Española de Gastroenterología; Asociación...

Terminated

Aggressive Versus Non-aggressive Goal-directed Fluid Resuscitation in Acute Pancreatitis (WATERFALL)

Acute Pancreatitis

Spain
Juan Francisco Delgado Jimenez
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III

Active, not recruiting

MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT) (LEONE-HT)

Antibody-mediated Rejection | Heart Transplant Rejection | Transplant Failure

Spain
Celia Bañuls
Instituto de Salud Carlos III

Active, not recruiting

Gut Microbiota, Mitochondrial Function and Metabolic Health in Obesity

Obesity Adult Onset

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III; European Regional Development Fund; Maternal,...

Unknown

Usefulness of Protein-enriched Infant Formula in Pediatric Intensive Care.

Protein-Energy Malnutrition

Spain
Massachusetts General Hospital
Broad Institute; Instituto Carlos Slim de la Salud

Active, not recruiting

Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS (SCRAMBLED EGGS)

Type 2 Diabetes | Genetics | Metabolism

United States
Fundació Institut de Recerca de l'Hospital de la...
Sociedad Española de Neumología y Cirugía Torácica; Instituto de Salud Carlos...

Unknown

Mechanisms of Lung Defense and Their Relationship With Airway Infection in Chronic Obstructive Pulmonary Disease (COPD)

Bacterial Infection in COPD

Spain
Instituto Aragones de Ciencias de la Salud
Andaluz Health Service; Instituto de Salud Carlos III; Red de Investigación en... and other collaborators

Completed

Multi-PAP: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy (Multi-PAP)

Multimorbidity | Polypharmacy | Other Diagnoses, Comorbidities, and Complications

Spain
Fondazione Don Carlo Gnocchi Onlus
Carlo Besta Neurological Institute

Recruiting

SECONDs' Italian Translation and Transcultural Validation (IT-SECONDs)

Disorder of Consciousness

Italy
Igenomix
Instituto Universitario IVI

Completed

Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility

Azoospermia | Abnormal Spermatogenesis

Spain
IVI Madrid
Instituto Valenciano de Infertilidad, IVI VALENCIA; Instituto Valenciano de...

Unknown

Use of Corifolitropin Alfa in Oocyte Donors

Infertility | Female Reproductive Problem

Spain
Instituto Valenciano de Infertilidad, IVI VALENCIA
IVI Madrid

Recruiting

Study of the ZyMōt Sperm Selection Method and Its Effect on Embryo Ploidy. (ZYMOT2)

Infertility, Male | Sperm Count, Low

Spain
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Do müllerian Anomalies Affect Embryo Implantation? (AM)

Uterine Diseases
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Risk of Ectopic Pregnancy and Variation of Luteal Estradiol and Progesterone Levels in IVF

Ectopic Pregnancy
Instituto Valenciano de Infertilidad, IVI VALENCIA
IVI Vigo; IVI Madrid; IVI Sevilla; IVI Barcelona; Hospital Universitario La Paz; IVI... and other collaborators

Terminated

Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer (PREECLAM-2019)

Pre-Eclampsia | Frozen Embryo Transfer

Spain
Ignacio J. Amat Santos
Instituto de Salud Carlos III; Gerencia Regional de Salud de Castilla y Leon

Recruiting

Validation of Accurate Commissural Alignment During Transcatheter Aortic Valve Implantation (ACA)

Severe Aortic Valve Stenosis

Spain
Fundació Sant Joan de Déu
Instituto de Salud Carlos III; European Union; University of Barcelona; Red Salud...

Unknown

Effectiveness of Repeated MOTivational InterVention to Reduce Ethanol Intake During prEgnancy (EMOTIVE)

Alcohol Abuse in Pregnancy

Spain
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

hCG Concentration in Peripheral Maternal Blood After Embryo Transfer, Ongoing Pregnancy Rates, and Morphokinetics

hCG

Spain
Instituto Valenciano de Infertilidad, IVI VALENCIA
IVI Barcelona; IVI Bilbao; Igenomix

Completed

Microbiome and Endometrial Receptivity in Obese Infertile Women

Endometrial Receptivity

Spain
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III; University of Navarra; Fundación para la Investigación...

Unknown

Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF (CARDIA-STIFF)

Diabetes Mellitus, Type 2 | Heart Failure With Preserved Ejection Fraction

Spain
Red de Terapia Celular
Instituto de Salud Carlos III; University of Valladolid; Centro en Red de Medicina...

Withdrawn

Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV) (MSV-DISC)

Degenerative Disc Disease
Fundacion Agencia Aragonesa para la Investigacion...
GlaxoSmithKline; Universidad de Zaragoza; Instituto de Salud Carlos III; Université... and other collaborators

Recruiting

Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy (BLMs4BU)

Buruli Ulcer

Benin
Milagros Rocha Barajas
Instituto de Salud Carlos III

Recruiting

Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective

Periodontal Diseases

Spain

Clinical Trials Sponsored by Instituto Carlos III

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