Clinical Trials Sponsored by InterveXion Therapeutics, LLC

Total 408 results

Translumina Therapeutics LLP
Iqvia Pty Ltd

Recruiting

A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry)

Cardiovascular Diseases

India, Italy, Netherlands
Cingulate Therapeutics
Premier Research Group plc

Active, not recruiting

Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301

ADHD | Attention Deficit Hyperactivity Disorder | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined | Attention Deficit Hyper Activity | Attention-deficit Hyperactivity

United States
Larimar Therapeutics, Inc.
Veristat, Inc.; Metrum Research Group, LLC

Completed

Single Ascending Dose Study of CTI-1601 Versus Placebo in Subjects With Friedreich's Ataxia

Friedreich Ataxia

United States
Effector Therapeutics
Medpace, Inc.; ICON plc

Active, not recruiting

Tomivosertib Combined With Pembrolizumab in Subjects With PD-L1 Positive NSCLC (KICKSTART) (KICKSTART)

Non-small Cell Lung Cancer

United States, Australia, Georgia
Rise Therapeutics LLC
University of Colorado, Denver; Mayo Clinic

Recruiting

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

Ulcerative Colitis | Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic | Ulcerative Colitis Chronic Mild

United States
ImmunoChem Therapeutics, LLC
National Cancer Institute (NCI); Northwestern Medicine

Recruiting

MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases (MW151-102)

Cognitive Dysfunction, Cognitive Disorder

United States
Antengene Therapeutics Limited
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors

Australia, China
Jonathan H. Waters
HbO2 Therapeutics LLC

Available

Expanded Access IND Administration of HBOC-201 in Patients With Severe Acute Anemia

Anemia Severe

United States
HemoShear Therapeutics
Prometrika, LLC; AllStripes Research Inc.; Genome Medical

Terminated

Natural History Study of Patients With Methylmalonic Acidemia and Propionic Acidemia (JUMP)

Propionic Acidemia | Methylmalonic Acidemia

United States, Canada, United Kingdom
Talaris Therapeutics Inc.
Northwestern University; Duke University; Regenerex, LLC

Terminated

Induction of Donor Specific Tolerance in Recipients of Living Kidney Allografts by Donor FCRx Infusion

Kidney Failure

United States
Larimar Therapeutics, Inc.
Veristat, Inc.; Metrum Research Group, LLC

Completed

Multiple Ascending Dose Study of CTI-1601 Versus Placebo in Subjects With Friedreich's Ataxia

Friedreich Ataxia

United States
Horizon Therapeutics, LLC

Completed

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States, Canada
Georgetown University
Merck Sharp & Dohme LLC; BioXcel Therapeutics Inc

Recruiting

BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (EXPEL PANC)

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Rapa Therapeutics LLC
Massachusetts General Hospital; Hackensack Meridian Health

Not yet recruiting

RAPA-501 Therapy for ALS

Amyotrophic Lateral Sclerosis

United States
Rapa Therapeutics LLC
Massachusetts General Hospital; Hackensack Meridian Health

Available

RAPA-501 Therapy for ALS EAP

Amyotrophic Lateral Sclerosis

United States
Lowell Anthony, MD
TerSera Therapeutics LLC

Terminated

Telotristat With Lutathera in Neuroendocrine Tumors

Neuroendocrine Tumors

United States
Olatec Therapeutics LLC
CTI Clinical Trial and Consulting Services

Terminated

Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome

Covid19 | Cytokine Release Syndrome

United States, Switzerland
Nektar Therapeutics
Merck Sharp & Dohme LLC; SFJ Pharmaceuticals, Inc.

Terminated

BEMPEG With Pembrolizumab vs Pembrolizumab Alone in Patients With Metastatic or Recurrent HNSCC (PROPEL-36)

Recurrent Head and Neck Cancer | Metastatic Head and Neck Cancer

United States, Austria, Greece, Italy
Insight Therapeutics, LLC
Brown University; Case Western Reserve University

Unknown

High-Dose Influenza Vaccine in Nursing Homes

Influenza

United States
Rare Thyroid Therapeutics International AB
Premier Research Group plc; Egetis Therapeutics

Recruiting

Withdrawal of Tiratricol Treatment in Males With Monocarboxylate Transporter 8 Deficiency (MCT8 Deficiency) (ReTRIACt)

Monocarboxylate Transporter 8 Deficiency | Allan-Herndon-Dudley Syndrome

United States, United Kingdom, Netherlands
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
Jonathan Stine
Grifols Therapeutics LLC

Withdrawn

Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis (PiVoT)

Cirrhosis, Liver | Portal Vein Thrombosis

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Efficacy and Safety of NFC-1 in Adolescents With Genetic Disorders Impacting mGluR and ADHD

Attention Deficit Disorder With Hyperactivity

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

A Non-interventional Study to Identify Children and Adolescents With ADHD and With or Without mGLuR Mutations

Attention Deficit Hyperactivity Disorder

United States
The Center for Rheumatic Disease, Allergy, & Immunology
Grifols Therapeutics LLC

Completed

Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections

Infections | IgG Deficiency

United States
Serhat Gumrukcu, MD PhD
Frida Therapeutics LLC

Recruiting

Clinical Specimen Collection From Pompe Disease Patients

Pompe Disease

United States
Jeffrey Clarke
Merck Sharp & Dohme LLC; Grid Therapeutics

Suspended

Study of GT103 in Combination With Pembrolizumab in Refractory, Metastatic Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer | Metastatic NSCLC | Recurrent Non Small Cell Lung Cancer

United States
Insight Therapeutics, LLC
Brown University; Case Western Reserve University; Seqirus

Completed

Adjuvanted Influenza Vaccination in U.S. Nursing Homes

Influenza | Influenza-like Illness

United States
Intensity Therapeutics, Inc.
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 (IT-01)

Sarcoma | Lymphoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Bile Duct Cancer | Colon Cancer | Liver Cancer | Squamous Cell Carcinoma | Chordoma of Sacrum

United States, Canada
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury

Acute Lung Injury | ARDS | COVID-19 Pneumonia

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations

Attention Deficit Hyperactivity Disorder

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Pharmacokinetic and Tolerability Study of NFC-1 in Subjects Aged 6-17 Years With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

A Noninterventional Genotype/Phenotype Study of mGluR Mutations in Children and Adolescents With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Instituto Grifols, S.A.
Hospital Clinic of Barcelona

Completed

Effects of Long Term Albumin 20% Administration in Patients With Cirrhosis and Ascites.

Cirrhosis | Ascites

Spain
Factor Therapeutics Ltd.
Parexel; ARANZ Medical; Almac Clinical Services LLC

Unknown

Study of VF001-DP in Patients With Chronic Venous Leg Ulcers

Pathologic Processes | Cardiovascular Diseases | Vascular Diseases | Skin Diseases | Ulcer | Leg Ulcer | Skin Ulcer | Varicose Ulcer

United States
Mindful Diagnostics and Therapeutics, LLC
Infectious Disease Society of America

Not yet recruiting

Tdap and Biomarkers of Alzheimer's Disease

Alzheimer Disease, Late Onset

United States
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions

22q11.2 Deletion Syndrome

United States
University College, London
Merck Sharp & Dohme LLC; Celleron Therapeutics Ltd.

Withdrawn

A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-Cell Lymphoma (PLACARD)

Diffuse Large B Cell Lymphoma
Viela Bio
MedImmune LLC

Completed

A Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases

Dermatomyositis, Polymyositis, Sjogren's, SLE, SSc

United States
Schön Klinik Berchtesgadener Land
Grifols Therapeutics LLC; Alpha-1 Foundation

Completed

Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients

Chronic Obstructive Pulmonary Disease | Alpha-1-antitrypsin-deficiency

Germany
Intensity Therapeutics, Inc.
Premier Research Group plc

Recruiting

A Study to Investigate Efficacy & Safety of INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3) (INVINCIBLE-3)

Sarcoma,Soft Tissue

United States
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
Insight Therapeutics, LLC
Brown University; Genentech, Inc.; Case Western Reserve University

Active, not recruiting

Baloxavir Versus Oseltamivir for Nursing Home Influenza Outbreaks

Influenza | Influenza, Human | Influenza -Like Illness

United States
Johns Hopkins University
University of Wisconsin, Madison; Frantz Viral Therapeutics, LLC

Completed

Intra-Anally Administered Artesunate in Patients With High-Grade Anal Intraepithelial Neoplasia (AIN 2/3) (ART-AIN)

Precancerous Conditions | Human Papilloma Virus | Anal Dysplasia | HPV-Related Anal Intraepithelial Neoplasia | AIN2/3 | Artesunate | Alternative Treatment

United States
H. Lee Moffitt Cancer Center and Research Institute
Minneamrita Therapeutics LLC

Terminated

Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
SPR Therapeutics, Inc.
United States Department of Defense; NDI Medical, LLC

Completed

Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System

Phantom Limb Pain | Residual Limb Pain | Post-Amputation Pain

United States
Durata Therapeutics Inc., an affiliate of Allergan...

Completed

Study on the Safety and Efficacy of Dalbavancin Versus Active Comparator in Adult Participants With Osteomyelitis

Osteomyelitis

Ukraine

Clinical Trials Sponsored by InterveXion Therapeutics, LLC

Sponsors and Collaborators

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