Clinical Trials Sponsored by JayMac+Pharmaceuticals+LLC

Total 629 results

Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)

Solid Tumor
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Terminated

A Study of Ridaforolimus in Non-Small Cell Lung Cancer (NSCLC) Patients With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutations (MK-8669-021 AM1)

Non-Small Cell Lung Cancer
University of Rochester
Cubist Pharmaceuticals LLC

Terminated

Daptomycin Versus Placebo in Patients With Neutropenia and Fever

Febrile Neutropenia

United States
University of Washington
Merrion Pharmaceuticals, LLC

Completed

ACY-6 Oral Administration of Acyline (ACY-6)

Contraception

United States
SCRI Development Innovations, LLC
Aventis Pharmaceuticals

Completed

Docetaxel Followed by Doxorubicin Plus Cyclophosphamide for Node Positive or High-Risk Primary Breast Cancer

Breast Cancer
Hvidovre University Hospital
Amylin Pharmaceuticals, LLC.

Completed

Amylin and Glucagon-Like Peptide-1 (GLP-1): Influence on Gastric Emptying, Appetite and Food Intake in Humans

Diabetes

Denmark
Ariad Pharmaceuticals
United BioSource, LLC

Terminated

An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG® (OMNI)

Myeloid Leukemia, Chronic-Phase, Accelerated-Phase, Blast-Phase, Ph+ALL

United States
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Terminated

LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies

Small Cell Lung Cancer | Ovarian Cancer

United States
Syndax Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer

Melanoma | Non-Small Cell Lung Cancer | Mismatch Repair-Proficient Colorectal Cancer

United States
Merck Sharp & Dohme LLC
Novartis Pharmaceuticals

Completed

A Study of the Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022)

Melanoma | Solid Tumors
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Completed

Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer

Prostate Cancer

United States
Novartis Pharmaceuticals
XOMA (US) LLC

Completed

Study of HCD122 in Adults With Non-Hodgkin's or Hodgkin's Lymphoma Who Have Progressed After at Least Two Prior Therapies

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma

United States, Belgium, Canada, Italy, France, Hong Kong, Australia, United Kingdom, Singapore, Korea, Republic of, Germany
Ironwood Pharmaceuticals, Inc.
Allergan Sales, LLC

Completed

A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Irritable Bowel Syndrome Characterized by Constipation

United States
Xeris Pharmaceuticals
The Emmes Company, LLC

Completed

Glucose Response of G-Pen (Glucagon Injection) in Pediatric T1D Patients

Diabetes Mellitus, Type 1

United States
Montefiore Medical Center
Amylin Pharmaceuticals, LLC.

Completed

Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
University of Miami
Graceway Pharmaceuticals, LLC

Completed

Topical Imiquimod in Conjunction With Nd:YAG Laser for Tattoo Removal

Healthy

United States
Janssen Research & Development, LLC
Janssen Pharmaceuticals

Completed

Study of Acute Uncomplicated Seasonal Influenza A in Adult Subjects

Influenza A

United States, Germany, Bulgaria, Canada, Estonia, Latvia, Belgium, Puerto Rico
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Lipid Metabolism, Inborn Errors | Hypobetalipoproteinemias | Hypolipoproteinemias | Hypolipopro... and other conditions

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

Hypercholesterolemia | Coronary Heart Disease

South Africa, Germany, United States, United Kingdom, Canada, Czech Republic
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Ridaforolimus (AP23573/MK-8669) in Participants With Taxane-Resistant Androgen-Independent Prostate Cancer (AIPC)(MK-8669-017)

Prostate Cancer

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)

Lymphoma | Multiple Myeloma | Tumors
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Hematologic Malignancies | Myeloid Metaplasia

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)

Glioblastoma | Malignant Glioma | Gliosarcoma

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Study of Oral Ridaforolimus (AP23573, MK-8669) to Treat Patients With Refractory or Advanced Malignancies (MK-8669-016 AM4)(COMPLETED)

Cancer
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

A Combination Study With Ridaforolimus (MK8669) and Dalotuzumab (MK0646) in Patients With Advanced Cancer (8669-004)

Neoplasms
Lotus Clinical Research, LLC
Novartis Pharmaceuticals

Completed

An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS

Pain | Delayed Onset Muscle Soreness

United States
Novartis Pharmaceuticals
XOMA (US) LLC

Terminated

Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy

Chronic Lymphocytic Leukemia

United States
Frankel, Amylynne, M.D.
Graceway Pharmaceuticals, LLC

Unknown

Imiquimod 3.75% Cream in Combination With Cryotherapy in the Treatment of Hypertrophic Actinic Keratoses

Actinic Keratosis

United States
University of Washington
Merrion Pharmaceuticals, LLC

Completed

ACY-7 Oral Administration of Acyline (ACY-7)

Healthy

United States
SCRI Development Innovations, LLC
Aventis Pharmaceuticals

Completed

Weekly Docetaxel and CMF in the Adjuvant Treatment of Elderly Women With High-Risk Breast Cancer

Breast Cancer
SCRI Development Innovations, LLC
Aventis Pharmaceuticals

Completed

Adjuvant Docetaxel and Estramustine Phosphate for High Risk Localized Prostate Cancer

Prostate Cancer

United States
SCRI Development Innovations, LLC
Aventis Pharmaceuticals

Completed

Weekly Docetaxel Versus Weekly Docetaxel/Gemcitabine in the Treatment of Non-Small Cell Lung Cancer in Elderly Patients

Lung Cancer

United States
Merck Sharp & Dohme LLC
Novartis Pharmaceuticals

Completed

Study to Evaluate Drug-drug Interaction Between Valopicitabine and Ribavirin

Chronic Hepatitis C

United States
HonorHealth Research Institute
Merck Sharp & Dohme LLC; Salarius Pharmaceuticals, LLC

Withdrawn

Pilot Trial of SP-2577 Plus Pembrolizumab in Select Gynecologic Cancers

Ovarian Endometrioid Adenocarcinoma | Endometrial Cancer | SCCOHT | Ovarian Clear Cell Tumor

United States
Sun Pharmaceutical Industries Limited
bioRASI, LLC

Completed

Bio-equivalence Study Between SAPHRIS and Asenapine (ASN)

Schizophrenia | Bipolar Disorder

United States
GE Healthcare
Pharmaceutical Product Development, LLC

Completed

An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)

Coronary Artery Disease (CAD)

United States, Germany, Switzerland, Canada, Netherlands, France, Finland
Fervent Pharmaceuticals
ICON plc

Completed

FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms

Vasomotor Symptoms | Menopause

United States
Alexion Pharmaceuticals, Inc.
Portola Pharmaceuticals, LLC (a wholly owned subsidiary of Alexion Pharmaceuticals)

Terminated

Study Evaluating Betrixaban in Pediatric Participants

VTE Prophylaxis

United States, United Kingdom, Russian Federation, Ukraine
Cheryl Rosenfeld, DO
Amylin Pharmaceuticals, LLC.

Unknown

Efficacy Study of High Dose Symlin to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
University of Maryland, Baltimore
Cubist Pharmaceuticals LLC

Completed

Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections

Fasciitis, Necrotizing | Fournier's Gangrene | Severe Necrotizing Skin and Soft Tissue Infections

United States
King Hussein Cancer Center
Hikma Pharmaceuticals LLC

Completed

Use of Intravenous Ferric Carboxymaltose in Treatment of Anemia in Cancer Patients Undergoing Chemotherapy

Cancer | Anemia
Pacira Pharmaceuticals, Inc
Lotus Clinical Research, LLC

Completed

Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction

Dental Pain

United States
Novartis Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Telbivudine in Adults Previously Treated in Idenix-Sponsored Telbivudine Studies

Chronic Hepatitis B

United States, Australia, Canada, China, Czechia, France, Germany, Hong Kong, India, Israel, Italy, Korea, Republic of, New Zealand, Poland, Puerto Rico, Singapore, Spain, Taiwan, Thailand, Turkey, United Kingdom
Novartis Pharmaceuticals
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy Study of Pazopanib and MK 3475 in Advanced Renal Cell Carcinoma (RCC; KEYNOTE-018)

Carcinoma, Renal Cell

United States, United Kingdom
Southeast Clinical Research Associates, LLC
Regeneron Pharmaceuticals

Withdrawn

Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab

Diabetic Macular Edema

United States
M.D. Anderson Cancer Center
Cubist Pharmaceuticals LLC

Completed

Daptomycin in the Treatment of Catheter-Related Staphylococcus Aureus

Staphylococcus Aureus

United States
SCRI Development Innovations, LLC
Novartis; Aventis Pharmaceuticals

Completed

Docetaxel Plus Imatinib Mesylate in Metastatic Breast Cancer

Breast Cancer

United States

Clinical Trials Sponsored by JayMac+Pharmaceuticals+LLC

Sponsors and Collaborators

Medical Conditions

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CROs in South Africa

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