Clinical Trials Sponsored by Loxbridge Research LLP

Total 1808 results

Janssen Research & Development, LLC

Completed

An Exploratory Genetic Study in Participants With Psoriasis

Psoriasis

United States, Canada
Janssen Research & Development, LLC

Completed

A Pharmacodynamic Study of Dapoxetine Concomitantly Administered in Participants Taking Terazosin

Ejaculation

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of Norgestimate /Ethinyl Estradiol (NGM/EE) Tablets Manufactured at 2 Different Facilities

Healthy

Netherlands
Janssen Research & Development, LLC

Completed

An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy

Diabetes Mellitus, Type 2

United States, Romania, Canada, Russian Federation, Czech Republic, Slovakia, Mexico
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study of the Effects of Canagliflozin on Plasma Volume in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Plasma Volume

Germany
Janssen Research & Development, LLC

Completed

An Observational Study of Continuous Oral Dosing of Abiraterone Acetate in Castration-Resistant Prostate Cancer Patients Evaluating Androgens and Steroid Metabolites in Bone Marrow Plasma

Prostate Neoplasms

United States
Janssen Research & Development, LLC

Terminated

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia

Pneumonia, Bacterial | Pneumonia, Ventilator-Associated | Nosocomial Infection | Community-Acquired Infections

Poland, Ukraine, United States, Argentina, Colombia, Brazil, Panama, Lithuania, Mexico, Latvia
Janssen Research & Development, LLC

Completed

A Crossover Study to Evaluate Relative Bioavailability of Two JNJ-54781532 Tablet Formulations in Healthy Adult Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Study of Abiraterone Acetate in Patients With Severe Hepatic Impairment Compared to Patients With Normal Hepatic Function

Hepatic Impairment

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42721458 in Healthy Male Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Study of Tapentadol Immediate-Release in the Treatment of Patients With Acute Pain From Bunionectomy

Hallux Valgus

Korea, Republic of
Janssen Research & Development, LLC

Withdrawn

A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies

Heart Failure
Janssen Research & Development, LLC

Completed

A Study of the Safety and Efficacy of Ustekinumab in Patients With Psoriatic Arthritis With and Without Prior Exposure to Anti-TNF Agents

Arthritis, Psoriatic

United States, France, Poland, United Kingdom, Germany, Canada, Sweden, Russian Federation, Austria, Hungary
Janssen Research & Development, LLC

Terminated

A Study of Doripenem in CerebrospinalFluid After Doripenem Administration in Pediatric Patients Less Than 1 Year of Age

Meningitis

Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)

Diabetes Mellitus, Type 2

United States, Poland, Colombia, Mexico, Portugal, Bulgaria, India, Malaysia, Turkey, Ukraine, Greece, Sweden, Singapore, Czech Republic, Argentina, Puerto Rico, Russian Federation, Thailand, Slovakia, Latvia, Estonia, Peru
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Healthy Volunteers

Healthy

Belgium
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Extended-Release (ER) Paliperidone in Adolescent Participants With Schizophrenia

Schizophrenia

Ukraine, United States, Spain, India, Romania, Russian Federation, Slovakia
Janssen Research & Development, LLC

Completed

An Observational Study of Oral Fluoroquinolones and the Risk of Retinal Detachment

Retinal Detachment
Janssen Research & Development, LLC

Completed

An Expanded Access Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer Who Have Completed Clinical Study COU-AA-001

Prostate Neoplasms

United Kingdom
Janssen Research & Development, LLC

Completed

A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States, Canada
Janssen Research & Development, LLC

Completed

A QT/QTc and Multi-Dose Pharmacokinetic Study of Abiraterone Acetate Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States, Canada
Janssen Research & Development, LLC

Completed

A Study to Compare Capillary and Venous Whole Blood and Plasma Concentrations of Five Antipsychotics

Healthy

Belgium
Janssen Research & Development, LLC

Completed

A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet

Healthy Participants

United States
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Interaction Study Between TMC435, Atorvastatin and Simvastatin in Healthy Participants

Healthy Participants

United States
Janssen Research & Development, LLC

Completed

A Pharmacokinetic Study to Evaluate the Dose-Proportionality of Tramadol (ULTRAM) Extended-Release (ER) in Healthy Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Pharmacokinetics and Pharmacodynamics of Canagliflozin in Healthy Chinese Volunteers

Healthy

China
Janssen Research & Development, LLC

Terminated

A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive Disorder

Depression

United States
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study of Canagliflozin and Metformin Immediate Release (150 mg/500 mg) FDC Tablets in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Healthy

United States
HeartDrug Research LLC
Novartis

Unknown

Effects of Valsartan and Aliskiren on Hemostatic Indices in Hypertensive Diabetics

Diabetes Mellitus

United States
Janssen Research & Development, LLC

Recruiting

A Study of Nipocalimab in Reducing the Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) (FREESIA-1)

Thrombocytopenia, Neonatal Alloimmune

Spain, Belgium, Norway, Slovakia, Italy, Sweden
Janssen Research & Development, LLC

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (QUASAR Jr)

Colitis, Ulcerative

Belgium, United States, China, Denmark, Spain, Japan, Italy, Turkey, Poland, France, Portugal
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Plaque Psoriasis

United States, Korea, Republic of, Taiwan, Germany, Poland, Brazil, Spain, Hungary, Australia, Canada, Romania
Janssen Research & Development, LLC

Recruiting

A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG) (SunRISe-5)

Non-Muscle Invasive Bladder Neoplasms

Korea, Republic of, United States, United Kingdom, China, Japan, Brazil, Argentina
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United Kingdom, United States, Poland, Germany, Brazil, Spain, Taiwan, Hungary, Japan, Canada, Argentina, Australia
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer

Advanced Prostate Cancer

France, United States
Janssen Research & Development, LLC

Recruiting

Global Patient Registry of Inherited Retinal Diseases (EYERD Registry)

Inherited Retinal Diseases

United States, Korea, Republic of, Canada, Spain, Denmark, Germany, France, Italy, Austria, United Kingdom, Israel, Brazil
Janssen Research & Development, LLC

Recruiting

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (AZALEA)

Hemolytic Disease of the Fetus and Newborn

Israel, Japan, Australia, United States, United Kingdom, Brazil
Janssen Research & Development, LLC

Recruiting

A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC (LIBERTAS)

Metastatic Castrate-sensitive Prostate Cancer

United States, France, Mexico, Germany, Australia, Brazil, Canada, China, Poland
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Geographic Atrophy

Netherlands, United States, Belgium, Italy, Germany, United Kingdom, Denmark, Spain, Czechia, Switzerland, Turkey, Canada, Hungary, Portugal, Poland, Australia, Sweden
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (PALOMA-2)

Carcinoma, Non-small-Cell Lung

United States, Korea, Republic of, Italy, Israel, Malaysia, United Kingdom, China, Brazil, Spain, Germany, Japan, France
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer (METalmark)

Carcinoma, Non-Small-Cell Lung

Korea, Republic of, China, Germany, United States, Brazil, Italy, Spain, France, Canada, Japan, Poland, Turkey, United Kingdom
Janssen Research & Development, LLC

Recruiting

A Study of Daratumumab

Multiple Myeloma

Korea, Republic of, Russian Federation, Spain, Germany, Belgium, Denmark, Greece, France, United States, Ukraine, Poland
Janssen Research & Development, LLC

Recruiting

A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies (SPIREA)

Myositis

United States, Korea, Republic of, Italy, United Kingdom, Hungary, Spain, Japan, Czechia, France, Mexico, Germany, Canada, Poland
Janssen Research & Development, LLC

Recruiting

A Study of Talquetamab and Teclistamab Each in Combination With a Programmed Cell Death Receptor-1 (PD-1) Inhibitor for the Treatment of Participants With Relapsed or Refractory Multiple Myeloma (TRIMM-3)

Relapsed/ Refractory Multiple Myeloma

United States, Germany, Spain, France
Janssen Research & Development, LLC

Recruiting

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

United States, China, Taiwan, Korea, Republic of, Japan, France, Portugal, Spain, Czechia, Poland, Greece, United Kingdom

Clinical Trials Sponsored by Loxbridge Research LLP

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