Clinical Trials Sponsored by MethylGene Inc.

Total 35608 results

LifeSeasons Inc.
KGK Science Inc.

Completed

A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline

Healthy

United States
Eisai Korea Inc.

Completed

Symbenda Post-Marketing Surveillance (PMS)

Lymphoma, Non-Hodgkin | Multiple Myeloma | Lymphocytic Leukemia

Korea, Republic of
EpicentRx, Inc.
Prothex Pharma, Inc.

Completed

Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Chemoradiation for the Treatment of Oral Cancers (PREVLAR)

Oral Mucositis

United States
Milestone Pharmaceuticals Inc.
Medpace, Inc.

Completed

Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm (NODE-1)

Paroxysmal Supraventricular Tachycardia (PSVT)

United States, Canada
Eisai Inc.
H3 Biomedicine Inc.

Withdrawn

A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Including Participants Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy, INPUT-102

Urinary Bladder Neoplasms

United States
Liquidia Technologies, Inc.
Nuventra, Inc.

Completed

Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil (INSPIRE)

Primary Pulmonary Hypertension

United States
Actavis Inc.
Watson Laboratories, Inc.

Completed

Clinical Equivalence Study of Mometasone Nasal Spray

Seasonal Allergic Rhinitis

United States
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

A Safety and Efficacy Study in Patients With Gastric Cancer

Gastric Cancer

United States, Canada
SerenaGroup, Inc.
Kinetic Concepts, Inc.

Terminated

Clinical Trial to Evaluate Blister Graft Utilizing a Novel Harvesting Device for Treatment of Venous Leg Ulcers (Cellutome)

Venous Insufficiency of Leg | Impaired Wound Healing | Diabetic Ulcers

United States
Cogent Biosciences, Inc.
Seagen Inc.

Terminated

Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
Astex Pharmaceuticals, Inc.
Eisai Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
LifeSeasons Inc.
KGK Science Inc.

Completed

A Study to Investigate the Efficacy of Pain Bloc-R in Healthy Participants With Non-pathological Aches and Discomfort

Healthy

Canada
Clovis Oncology, Inc.
Genentech, Inc.

Terminated

A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC

Non-small Cell Lung Cancer

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic Patients

Hypercholesterolemia

United States
Calibra Medical, Inc.
Medpace, Inc.

Completed

Glycemic Control and Treatment Satisfaction Using Finesse Versus Pen for Initiating Bolus Insulin Dosing in Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

United States, France, United Kingdom, Germany
Astellas Pharma Inc
Medivation, Inc.

Completed

A Study to Test if Enzalutamide is Effective and Safe in Prostate Cancer Patients Who Have Never Had Hormone Therapy

Prostate Cancer

Belgium, Czechia, Denmark, Germany
Taiho Oncology, Inc.
Quintiles, Inc.

Completed

A Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With Capecitabine in Patients With Advanced Solid Tumors

Neoplasms

United States
Cascadian Therapeutics Inc.

Completed

Phase 1 Study of ONT-10 in Patients With Solid Tumors

Solid Tumors

United States
Cascadian Therapeutics Inc.

Completed

Phase I Trial of Oral PX-866

Advanced Solid Tumors

United States
Ocular Therapeutix, Inc.
ORA, Inc.

Completed

OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye

Dry Eye
Woodmont Pharmaceuticals, Inc.
ORA, Inc.

Terminated

Study Evaluating Safety of Ragweed Mix Given by Intralymphatic Node Injections

Allergic Rhinitis | Allergic Conjunctivitis

United States
Eisai Inc.
H3 Biomedicine Inc.

Completed

A Study to Evaluate the Food-Effect of H3B-6527

Healthy Participants

United States
Momenta Pharmaceuticals, Inc.
Mylan Inc.

Completed

Assessment of Pharmacokinetics (PK) and Safety of M834 and Orencia ®, in Healthy Subjects

Healthy Volunteers

United Kingdom
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 1 Study of Brentuximab Vedotin Given Sequentially and Combined With Multi-Agent Chemotherapy for CD30-Positive Mature T-Cell and NK-Cell Neoplasms

Lymphoma, Large-Cell, Anaplastic | Lymphoma, NK-cell | Lymphoma, T-cell

United States, United Kingdom
ImmunoVaccine Technologies, Inc. (IMV Inc.)

Completed

Phase 1 Study of a Cancer Vaccine to Treat Patients With Advanced Stage Ovarian, Fallopian or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States, Canada
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 2 Open Label Trial of Brentuximab Vedotin (SGN-35) for Systemic Anaplastic Large Cell Lymphoma

Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic

United States, France, Canada, Belgium, United Kingdom
Eisai Korea Inc.

Completed

A Multi-national Study to Identify Treatment Discontinuation Rate in de Novo Alzheimer's Disease Patients Who Have Been Newly Prescribed With Donepezil (Aricept) in Asia (ADOS) (ADOS)

Alzheimer's Disease

China, Taiwan, Korea, Republic of, Singapore, Thailand, Philippines
Deacon Biosciences, Inc.
ORA, Inc.

Completed

A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers

Ocular Infection

United States
Kinex Pharmaceuticals Inc.

Completed

Evaluation of KX2-391 in Elderly Subjects With Acute Myeloid Leukemia (AML)

Acute Myelogenous Leukemia

United States
FORUM Pharmaceuticals Inc
Quintiles, Inc.

Withdrawn

Study of the Safety of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Currently Receiving Memantine

Dementia | Alzheimer's Disease | Cognition

United States
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

Cardiac Safety Study of Brentuximab Vedotin (SGN-35)

Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin

United States, Germany
Mati Therapeutics Inc.
QLT Inc.

Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Ocular Hypertension | Open-Angle Glaucoma

United States
Eisai China Inc.

Completed

Drug Use Survey (DUS) of Triple Therapy (Methycobal (MBL)+ Myonal (MYO)+ Non-steroidal Anti-inflammatory Drags (NSAID)) on the Symptom Relief of Lumbar DDD in China

Lumbar Disc Degenerative Disease

China
Eisai Korea Inc.

Completed

A Multicenter Comparative Trial of Zonisamide and Topiramate as Initial Monotherapy in Untreated Epilepsies

Epilepsy

Korea, Republic of
MedRhythms, Inc.
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder (aNiMatO)

Neuromyelitis Optica Spectrum Disorder

United States
Technoderma Medicines Inc.
Therapeutics, Inc.

Recruiting

Study of TDM-180935 in Atopic Dermatitis Patients

Atopic Dermatitis

United States
Lyssn.io, Inc.
ProtoCall Services, Inc.

Not yet recruiting

The Use of Voice-Based AI in 988 Crisis Counseling

Suicide | Suicide and Self-harm
Sirtsei Pharmaceuticals, Inc.
Rho, Inc.

Recruiting

A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States
Lucid Diagnostics, Inc.

Recruiting

Lucid Registry Study (Lucid Registry)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States
Ceragem Clinical Inc.

Recruiting

CETIS-I (CEra Traction Improves Spine-I)

Lumbar Disc Herniation | Degenerative Spinal Stenosis | Spine Traction

Korea, Republic of
Ceragem Clinical Inc.

Recruiting

CEFID-II (CEra Flow Improves DVT-II)

Deep Vein Thrombosis | Blood Circulation Disorder

Korea, Republic of
HBI Solutions Inc.
mProbe Inc.

Not yet recruiting

Maternal Serum Markers Predicting Preeclampsia at Early Gestations

Preeclampsia
SerenaGroup, Inc.
Dabir Surfaces Inc

Recruiting

A Multicentre Prospective Study Evaluating an Off-loading Mattress Overlay System in Healing of Stage 3 Pressure Ulcers (DABIRPrU)

Pressure Ulcer

United States
NeuroActiva, Inc.
Biomed Industries, Inc.

Recruiting

NA-831, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection (NATADEX)

Coronavirus Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Severe Acute Respiratory Infection

United States
AVM Biotechnology Inc
Medpace, Inc.

Recruiting

The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies (OPAL)

Lymphoid Malignancies

United States
Lucid Diagnostics, Inc.

Recruiting

Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC (ESOGUARDBE2)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States, Netherlands
Mylan Pharmaceuticals Inc

Completed

Fed Study of (Parlodel®) 2.5 mg Bromocriptine Mesylate Tablets

Healthy

Canada
Mylan Pharmaceuticals Inc

Completed

Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Alprazolam Extended-Release Tablets 3 mg to Xanax XR® Tablets 3 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Verapamil HCl Extended-Release Capsules 300 mg to Verelan® PM Extended-Release Capsules 300 mg

Healthy

United States

Clinical Trials Sponsored by MethylGene Inc.

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Peru

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