Clinical Trials Sponsored by National Instutite of Health and Care Excellence

Total 7987 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Dyslipidemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Hypertension, Hypoxia and Sickle Cell Disease

Sickle Cell Anemia | Pulmonary Hypertension | Cerebrovascular Disease | Chuvash Polycythemia

United States, Russian Federation
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

Coronary Artery Disease

United States, Denmark
National Heart, Lung, and Blood Institute (NHLBI)

Completed

EW-A-401 to Treat Intermittent Claudication

Arteriosclerosis | Intermittent Claudication

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Biomarkers for Personalized Early Assessment of Response During Salvage Chemotherapy in People With Relapsed or Refractory Acute Myeloid Leukemia (PEARL15)

Acute Myeloid Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study to Evaluate the Effect of Nicotinamide Riboside on Immunity

Coronary Artery Disease | Diabetes | Atherosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiac MRI for Patients Enrolled in INFUSE-AMI

Coronary Artery Disease | Myocardial Fibrosis | Acute Myocardial Infarction | Myocardial Edema | Gadolinium

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gardasil Vaccination in Post Stem Cell Transplant Patients

Stem Cell Transplant | Immunogenicity | Gardasil Vaccine

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of Toxicity From Stem Cell Transplant

Hemolysis | Organ Dysfunction

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Researching Alveolar Macrophage Improvements With Supplements in HIV (RAISe)

HIV-1 Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Corticosteroids

Graft-Versus-Host Disease

United States
Northwestern University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Maternal-Offspring Metabolics:Family Intervention Trial (MOMFIT)

Pregnancy | Weight Gain

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders

Sickle Cell Disease | Sickle Cell Anemia | Chronic Hemolytic Disorders

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol

Healthy Volunteers | Statins | Immune Modulation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Myocardial Infarction | Ischemic Heart Disease | Angina, Unstable

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers

Multiple Myeloma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Graft vs Host Disease | Hematologic Neoplasm

United States
National Institutes of Health Clinical Center (CC)
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gadofosveset Trisodium for Heart Imaging Studies

Coronary Arteriosclerosis | Coronary Artery Disease (CAD) | Obstructive Coronary Artery Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Segmental Bronchoalveolar Lavage

Asthma | Pulmonary Fibrosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Effect of Nitrite on Exercise Physiology and Metabolism

Healthy | Healthy Volunteer | HV

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Blood Stem Cell Collection and Transplant Procedures

Acute Lymphoblastic Leukemia | Chronic Myelogenous Leukemia | Myelodysplastic Syndrome (MDS) | CLL (Chronic Lymphocytic Leukemia) | CML (Chronic Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma

Airway Inflammation | Severe, Refractory Asthma | Airflow Obstruction

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study of Mitochondrial Biology in Human Platelets

Diabetes | Insulin Resistance

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

MRI-Guided Balloon Angioplasty to Treat Blood Flow Blockage in the Legs

Cardiovascular Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease

Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Imatinib (Gleevec(Registered Trademark)) to Treat Chronic Myelomonocytic Leukemia and Atypical Chronic Myelogenous Leukemia

Chronic Myelomonocytic Leukemia | Chronic Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes

Congestive Heart Failure

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia

Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplantation to Treat Systemic Mastocytosis

Mastocytosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Hemoglobinuria, Nocturnal

United States
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

Asthma | Airway Inflammation | Airflow Obstruction | Airway Hyperactivity

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genetic Analysis of African-Americans With High Blood Pressure

Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy

Healthy | Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Atorvastatin to Treat Pulmonary Sarcoidosis

Sarcoidosis, Pulmonary

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia

Neutropenia | Pancytopenia | Aplastic Anemia | Severe Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of Oral Alpha-Cyclodextrin for Decreasing Serum Cholesterol

Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies

Hematologic Malignancies | Bone Marrow Transplant Rejection

United States
Emory University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Granulocyte-Macrophage Stimulating Factor in the Treatment of Peripheral Arterial Disease (GPAD-2)

Peripheral Arterial Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rilonacept to Improve Artery Function in Patients With Atherosclerosis

Coronary Artery Disease | Inflammation | Atherosclerosis | Endothelial Dysfunction

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Screening for Inherited Heart Disease

Heart Disease | Hypertrophic Cardiomyopathy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Long Term Effects of Enalapril and Losartan on Genetic Heart Disease

Myocardial Ischemia | Hypertrophic Cardiomyopathy | Left Ventricular Hypertrophy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mycophenolate Mofetil and Cyclosporine to Treat Relapsing Aplastic Anemia

Aplastic Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease

Coronary Arteriosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Muscle Abnormalities in Patients With Specific Genetic Mutations

Cardiomyopathy, Hypertrophic | Muscular Dystrophy, Oculopharyngeal

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty

Atherosclerosis | Peripheral Vascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medical Treatment for Diamond Blackfan Anemia

Hematologic Disease | Fanconi's Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women

Hypercholesterolemia | Postmenopause

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Lipoprotein Metabolism in Normal Volunteers and Patients With Abnormal Levels of Lipoproteins

Healthy | Hyperlipoproteinemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Hormone Replacement Therapy on Inflammation and Stiffening of Artery Walls

Healthy | Atherosclerosis | Vascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High Cholesterol

Hypertension | Hypercholesterolemia

United States

Clinical Trials Sponsored by National Instutite of Health and Care Excellence

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