Clinical Trials Sponsored by Prothena Biosciences Ltd.

Total 385 results

Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Enrolling by invitation

Extension Study of ABP-671 in Participants With Gout

Gout

United States, Georgia, Australia, Guatemala, Taiwan
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Withdrawn

JS001+IMP4297 in Patients With Advanced Cancer

Advanced Cancer
International Vaccine Institute
SK Bioscience Co., Ltd.

Unknown

Immune Non-inferiority and Safety of a Vi-DT Typhoid Conjugate Vaccine

Typhoid

Nepal
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors

Liver Cancer, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Cervical Cancer, MSI-H Colorectal Cancer

China
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA

Non-radiographic Axial Spondyloarthritis

China
SK Bioscience Co., Ltd.
International Vaccine Institute

Withdrawn

A Blood Collection Study to Assess the Immunogenicity of Nationally Authorized Homologous COVID-19 Booster Vaccines Among Adult Vaccinees.

COVID-19
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjects

Hyperuricemia | Gout

United States
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Completed

Study to Investigate the Effects of Food on Relative Bioavailability of ABP-671 Tablets in Healthy Subjects

Gout | Food-drug Interaction

United States
Chipscreen Biosciences, Ltd.
H & J CRO International, Inc.

Completed

Trial of Chiauranib Capsule on Pharmacokinetics to Assess the Effect of High Fat Diet in Healthy Volunteers

Healthy Volunteers

China
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral ABP-745 Administration in Healthy Volunteers (ABP-745)

Gout

United States
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active AS

Active Ankylosing Spondylitis

China
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Active, not recruiting

A Pharmacokinetic Study of JS002 in Healthy Subjects

Health Volunteer

China
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Completed

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of ABP-671 in Patients With Gout or Hyperuricemia

Hyperuricemia | Gout

Australia
Mabwell (Shanghai) Bioscience Co., Ltd.
Huashan Hospital

Completed

A Clinical Study in Health Subjects to Evaluate 9MW1411 Injection

Staphylococcus Aureus Infection

China
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671

Hyperuricemia | Gout

United States
Peking University
Shanghai Junshi Bioscience Co., Ltd.

Completed

Study of JS001 in Patients With Advanced Neuroendocrine Tumors

Neuroendocrine Tumors

China
Guangzhou Henovcom Bioscience Co. Ltd.
Heilongjiang Zhenbaodao Pharmaceutical Co., Ltd.

Completed

A Study of HNC042 in Healthy Chinese Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics

Influenza

China
Sun Yat-sen University
Guangzhou Gloria Biosciences Co., Ltd.

Recruiting

A Study of Zimberelimab(GLS-010) Combined With AVD for Newly Diagnosed Early-stage Hodgkin's Lymphoma

Classical Hodgkin Lymphoma

China
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Ovarian Epithelial Carcinoma

Ovarian Epithelial Carcinoma
UCB BIOSCIENCES GmbH
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 3b, Open-Label, Safety and Efficacy Study of Rotigotine as Add-On Therapy With Low Doses of Pramipexole or Ropinirole in Patients With Advanced Parkinson's Disease

Advanced Parkinson's Disease

Australia, Korea, Republic of, Malaysia, Singapore, Taiwan
Shantou University Medical College
Guangdong ProCapZoom Biosciences Co., Ltd.

Not yet recruiting

Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma
Enlivex Therapeutics Ltd.
Nordic Bioscience Clinical Development (NBCD)

Recruiting

Study of Intra-articular Allocetra in Knee Osteoarthritis

Osteoarthritis, Knee

Israel
Tel-Aviv Sourasky Medical Center
Fruitura Bioscience Ltd.

Completed

The Influence of Red Grape Cells on Blood Pressure Vascular Function in People With Hypertension (RGC)

Hypertension

Israel
Shanghai Chest Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

NSCLC

China
Polish Myeloma Consortium
Janssen-Cilag Ltd.; Bioscience, S.A.

Recruiting

Pre-emptive Daratumumab Therapy of Minimal Residual Disease Reappearance or Biochemical Relapse in Multiple Myeloma (PREDATOR)

Multiple Myeloma

Poland
Hangzhou YuYuan Bioscience Technology Co., Ltd.
LG Chem

Completed

Randomized Controlled Study of Comparing Follitrope Versus Gonal-f in Chinese Infertility Women.

Infertility, Female

China
North China Petroleum Bureau General Hospital
Joint Biosciences Ltd

Recruiting

Oncolytic Virus (OVV-01) Injection in the Treatment of Patients With Advanced Solid Tumors

Neoplasms

China
UCB BIOSCIENCES GmbH
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 4, Open-label Study to Assess the Feasibility and Efficacy on Motor and Non-motor Symptoms of Switching From Pramipexole or Ropinirole to Rotigotine Transdermal Patch in Subjects With Advanced Idiopathic Parkinson's Disease

Advanced Idiopathic Parkinson's Disease

Korea, Republic of, United States, Malaysia, Singapore, Taiwan
Zhejiang Cancer Hospital
Shanghai Junshi Bioscience Co., Ltd.

Suspended

A Study of Toripalimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma.

Esophageal Squamous Cell Carcinoma

China
Sahlgrenska University Hospital, Sweden
Beneo-Institute; Atmo Biosciences Pty Ltd

Recruiting

The Effects of Carbohydrates in Irritable Bowel Syndrome (FIBS)

Irritable Bowel Syndrome With Diarrhea

Sweden
Guangdong Provincial People's Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Neoadjuvant Immunotherapy in Rare Mutations Localized NSCLC

Non-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 Mutation

China
Eli Lilly and Company
Shanghai Junshi Bioscience Co., Ltd.

Completed

A Study of LY3832479 (LY-CoV016) in Healthy Participants 1

Healthy

United States
Sun Yat-sen University
Shanghai Junshi Bioscience Co., Ltd.

Unknown

JS001 Combined With Regorafenib in Patients With Advanced Colorectal Cancer

Colorectal Cancer

China
Peking University People's Hospital
Shanghai Junshi Bioscience Co., Ltd.

Not yet recruiting

Neoadjuvant Toripalimab for Non-squamous NSCLC With EGFR Mutation

EGFR Positive Non-small Cell Lung Cancer | Non Squamous Non Small Cell Lung Cancer
Sun Yat-sen University
Shanghai Weike Bioscience Co., Ltd.

Not yet recruiting

A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC

Nasopharyngeal Carcinoma | TNF | Chemo-radiotherapy
Sun Yan
Shanghai Junshi Bioscience Co., Ltd.

Not yet recruiting

Toripalimab Plus TPF Chemotherapy and Radiotherapy for LA-HPSCC

Hypopharyngeal Neoplasm Malignant Primary

China
Sun Yat-sen University
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

PD-1 Blockade Combined With De-intensification Radical Chemoradiotherapy in Nasopharyngeal Carcinoma (DIAMOND)

Nasopharyngeal Carcinoma

China
Shanghai Zhongshan Hospital
Shanghai Junshi Bioscience Co., Ltd.; OrigiMed

Completed

A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer

Biliary Tract Cancer

China
Sun Yat-sen University
Shanghai Junshi Bioscience Co., Ltd.

Not yet recruiting

An Open-label, Multicentre, Phase II/III RCT of PFLL Versus GP Combined With JS001 as the First-line Therapy for mNPC

Nasopharyngeal Carcinoma | Chemotherapy | Metastasis | Immunotherapy | Survival

China
Sun Yat-sen University
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

Efficacy of Perioperative Chemotherapy Plus PD-1 Antibody in the Locally Advanced Gastric Cancer

Gastric Cancer | Locally Advanced Solid Tumor

China
SK Bioscience Co., Ltd.
Coalition for Epidemic Preparedness Innovations

Completed

Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With Aluminum Hydroxide (COVID-19)

COVID-19 (Healthy Volunteers)

Korea, Republic of
S-Evans Biosciences Co., Ltd.
First Affiliated Hospital of Zhejiang University

Unknown

Using Human Menstrual Blood Cells to Treat Acute Lung Injury Caused by H7N9 Bird Flu Virus Infection

Acute Lung Injury | Multiple Organ Failure | Acute Respiratory Distress Syndrome (ARDS)

China
NHS Greater Glasgow and Clyde
University of Glasgow; Aurum Biosciences Ltd

Unknown

Perfluorocarbon (ABL-101) Oxygenation for Stroke: Trial With GOLD (Glasgow Oxygen Level Dependent Technology) Imaging Theranostic (POST-IT)

Acute Ischaemic Stroke
Northern Jiangsu Province People's Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Neoadjuvant Triprizumab and Radiotherapy in Operable Patients With Stage IIA-IIIA Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Neoadjuvant Therapy | Radiotherapy | Immunotherapy

China
Peking Union Medical College Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers

Advanced Biliary Tract Cancer

China
Peking Union Medical College Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Axitinib Plus Toripalimab as Second-line Treatment in Hepatobiliary Malignant Tumors

Hepatobiliary Neoplasm | Liver Neoplasm | Biliary Tract Neoplasms

China
SK Bioscience Co., Ltd.
GlaxoSmithKline; Coalition for Epidemic Preparedness Innovations

Active, not recruiting

Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With or Without AS03 (COVID-19)

COVID-19 (Healthy Volunteers)

Korea, Republic of
Mabwell (Shanghai) Bioscience Co., Ltd.
Shanghai Public Health Clinical Center

Completed

A Clinical Study to Evaluate MW33 Injection

Covid19

China
Nanfang Hospital, Southern Medical University
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Toripalimab Combined With Neoadjuvant Chemoradiotherapy as First-line Treatment for Locally Advanced，High-Risk，MSS Rectal Cancer

Rectal Cancer | MSS | Locally Advanced | High-Risk

China
Peking Union Medical College Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Lenvatinib Combined Toripalimab in Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

China

Clinical Trials Sponsored by Prothena Biosciences Ltd.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations