Clinical Trials Sponsored by Rigel Pharmaceuticals

Total 20035 results

Johnson & Johnson Pharmaceutical Research & Development...
Peninsula Pharmaceuticals, Inc.

Completed

Doripenem in the Treatment of Ventilator-Associated Pneumonia

Pneumonia | Ventilators, Mechanical
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Terminated

A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer

NSCLC

United States
Basilea Pharmaceutica
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study Evaluating the Pharmacokinetics of Ceftobiprole When Taken by Obese Patients

Obesity | Streptococcal Infections | Staphylococcal Skin Infections
Basilea Pharmaceutica
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Single-Dose Pharmacokinetics and Safety Study of Ceftobiprole in Pediatric Patients =3 Months to <18 Years of Age

Streptococcal Infections | Staphylococcal Skin Infections
Basilea Pharmaceutica
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Pharmacokinetic Study,Ceftobiprole,Healthy Volunteers,Healthy Patients With End Stage Renal Disease

Streptococcal Infections | Staphylococcal Skin Infections
Massachusetts General Hospital
Alkermes, Inc.; Otsuka America Pharmaceutical; Eisai Inc.; Janssen Pharmaceuticals and other collaborators

Recruiting

National Pregnancy Registry for Atypical Antipsychotics

Depression | Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Use of Atypical Antipsychotics During Pregnancy

United States
Dizal (Jiangsu) Pharmaceutical Co., Ltd.
PPD Development, L.P.

Recruiting

DZD9008 PK Study in Hepatic Impairment Subjects

Hepatic Impairment

United States
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Overseas Pharmaceuticals, Ltd.
Guangzhou Health Start Pharmaceutical Techology Co.,Ltd

Not yet recruiting

An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions

Hypertension

China
Tasly GeneNet Pharmaceuticals Co., Ltd

Recruiting

A Study to Assess the Efficacy and Safety of PXT3003 in Charcot-Marie-Tooth Type 1A

Charcot-Marie-Tooth Type 1A

China
Tetraphase Pharmaceuticals, Inc.
PRA Health Sciences

Completed

Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers (BAL)

Healthy Subjects

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.
Cephalon; ChemGenex Pharmaceuticals

Completed

Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation

Chronic Myeloid Leukemia

United States, Canada, France, Germany, Hungary, India, Italy, Poland, Singapore, United Kingdom
Auspex Pharmaceuticals, Inc.

Completed

Alternatives for Reducing Chorea in Huntington Disease (ARC-HD)

Chorea Associated With Huntington Disease

United States, Australia, Canada
University of Michigan Rogel Cancer Center
GlaxoSmithKline

Active, not recruiting

Clinical Trial of Consolidation Treatment With Iodine I 131 Tositumomab for Multiple Myeloma

Multiple Myeloma

United States
University of Michigan Rogel Cancer Center
Exelixis

Terminated

Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to Bone

Prostate Cancer Metastatic

United States
University of Michigan Rogel Cancer Center
Novartis

Withdrawn

RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.

Chronic Myeloid Leukemia

United States
University of Michigan Rogel Cancer Center
GlaxoSmithKline

Completed

Oral Estramustine and Oral Vinorelbine in the Treatment of Hormone-Refractory Prostate Cancer

Prostate Cancer

United States
University of Michigan Rogel Cancer Center
Pfizer

Terminated

Trial of Maintenance SUO11248 Versus Placebo Post Chemotherapy for Patients With Advanced Urothelial Carcinoma

Bladder Cancer

United States
University of Michigan Rogel Cancer Center
Takeda

Withdrawn

Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States
University of Michigan Rogel Cancer Center
Exelixis

Active, not recruiting

Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy

Advanced Adult Hepatocellular Carcinoma

United States
University of Michigan Rogel Cancer Center
Sanofi

Terminated

Salvage Radiation Therapy and Taxotere for PSA Failure After Radical Prostatectomy

Prostate Cancer

United States
University of Michigan Rogel Cancer Center
GlaxoSmithKline

Terminated

Trial of Low-Dose Methotrexate and I 131 Tositumomab for Previously Untreated, Advanced-Stage, Follicular Lymphoma

Follicular Lymphoma

United States
Teva Pharmaceuticals USA
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis

Osteoporosis, Postmenopausal

United States, Bulgaria, Czechia, Georgia, Germany, Hungary, Poland, Russian Federation, Slovakia, Ukraine
Auspex Pharmaceuticals, Inc.

Completed

Reducing Involuntary Movements in Participants With Tardive Dyskinesia (RIM-TD)

Tardive Dyskinesia

United States, Czechia, Germany, Hungary, Poland, Slovakia
Auspex Pharmaceuticals, Inc.

Completed

A Pilot Study Of SD-809 (Deutetrabenazine) In Moderate To Severe Tourette Syndrome (TS)

TOURETTE SYNDROME

United States
Auspex Pharmaceuticals, Inc.

Completed

Addressing Involuntary Movements in Tardive Dyskinesia (AIM-TD)

Tardive Dyskinesia

United States, Czechia, Germany, Hungary, Poland, Slovakia
University of Michigan Rogel Cancer Center
AstraZeneca

Terminated

Pharmacists Coordinated Care Oncology Model (PCOM) for Patients Taking Oral Anti-cancer Medications

Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Multiple Chronic Conditions

United States
University of Michigan Rogel Cancer Center
Novartis

Completed

Study of PTK787 in the Treatment of Patients With Non-Metastatic Androgen Independent Prostate Cancer

Prostate Cancer
University of Michigan Rogel Cancer Center
GlaxoSmithKline

Withdrawn

Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial Cancer

Bladder Cancer | Urothelial Cancer

United States
University of Michigan Rogel Cancer Center
Pfizer

Completed

Treatment for Patients With Metastatic Thyroid Cancer

Thyroid Cancer

United States
Telix Pharmaceuticals (Innovations) Pty Limited
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

68Ga-PSMA-11 Efficacy in Detecting BCR Prostate Cancer in Chinese Patients

Prostate Cancer | Biochemical Recurrence of Malignant Neoplasm of Prostate | BCR Prostate Carcinoma

China
Teva Branded Pharmaceutical Products R&D, Inc.
Cephalon; ChemGenex Pharmaceuticals

Completed

Open Label Study of Subcutaneous Homoharringtonine (Omacetaxine Mepesuccinate) in Patients With Advanced CML

Chronic Myeloid Leukemia

United States, Canada, France, Germany, Hungary, India, Italy, Poland, Singapore, United Kingdom
Auspex Pharmaceuticals, Inc.

Completed

Aim to Reduce Movements in Tardive Dyskinesia (ARM-TD)

Tardive Dyskinesia

United States, Poland, Czechia, Slovakia
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Study of the Combination of Rituximab, Cyclophosphamide, Doxorubicin, VELCADE, and Prednisone or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Mantle Cell Lymphoma

Mantle Cell Lymphoma

China, Belgium, Thailand, United States, Spain, Canada, Colombia, Italy, Morocco, Brazil, Turkey, Chile, Malaysia, Israel, Portugal, Singapore, Russian Federation, Philippines, Tunisia, Austria, Czechia, Germany, Hungary, India, Poland, R... and more
Teva Pharmaceuticals Europe

Completed

Study in Patients' With Persistent Asthma and Chronic Obstructive Pulmonary Disease (SPRINT)

Chronic Obstructive Pulmonary Disease | Asthma

Croatia, Denmark, Ireland, Italy, Netherlands, Norway, Portugal, Spain, Sweden, United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
Rigel Pharmaceuticals; Allegheny Singer Research Institute (also known as Allegheny...

Active, not recruiting

Clinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian Cancer

Ovarian Cancer

United States
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC

Squamous Cell Carcinoma of the Oropharynx | HPV16 Positive

Netherlands, United States, United Kingdom, France, Belgium, Czechia, Spain, Italy, Germany, Brazil, Hungary, Mexico, Poland
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 2 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 4 of 4)

Healthy Volunteers
Portola Pharmaceuticals

Completed

The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist

Hepatic Impairment

United States
Portola Pharmaceuticals

Withdrawn

BRAVO - Betrixaban Registry Using Real Time Observations in Acute Medical Illness to Assess Venous Thrombosis and Bleeding Outcomes

Venous Thromboses

United States
Jazz Pharmaceuticals
GW Pharmaceuticals

Completed

An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

Seizures | Tuberous Sclerosis Complex

United States
Solvay Pharmaceuticals
Unimed Pharmaceuticals

Completed

Observation Study of T-Gel (1%) in Treatment of Adolescent Boys With Hypogonadism

Primary or Secondary Hypogonadism | Constitutional Delay in Growth and Puberty (CDGP)

United States
Solvay Pharmaceuticals
Unimed Pharmaceuticals

Completed

Pharmacokinetic Evaluation of Testosterone Gel (1%)

Primary or Secondary Hypogonadism | Constitutional Delay in Growth and Puberty (CDGP)

United States
University of Michigan Rogel Cancer Center
Rogel Cancer Center Cancer Control and Population Sciences O-SURE initiative

Completed

Feasibility and Evaluation of a Self-care App to Enhance Purposeful Living

Ovarian Cancer

United States
Portola Pharmaceuticals

Completed

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 3 of 4)

Healthy Volunteers

United States
Portola Pharmaceuticals

Withdrawn

CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL)

AITL | Peripheral T-Cell Lymphoma (PTCL NOS) | Nodal Lymphomas of T Follicular Helper (TFH) | Follicular T-cell Lymphoma (FTCL) | ALCL | HSTCL | EATL I,II | MEITL, EATL Type II | Nasal Lymphoma
Portola Pharmaceuticals

Completed

A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban

Bleeding

United States
Regeneron Pharmaceuticals
Alnylam Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers

Healthy

Belgium
Ferring Pharmaceuticals
Xanodyne Pharmaceuticals

Completed

A Study of Tranexamic Acid (XP12B) in Women With Heavy Menstrual Bleeding

Menorrhagia

United States

Clinical Trials Sponsored by Rigel Pharmaceuticals

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