Clinical Trials Sponsored by Technological Centre of Nutrition and Health

Total 5296 results

National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Paroxysmal Nocturnal Hemoglobinuria (PNH) | Severe Aplastic Anemia (SAA) | Hypo-Plastic Myelodysplastic Syndrome (MDS)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults

Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Eltrombopag for People With Fanconi Anemia

Fanconi Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires

Congenital Heart Disease | Structural Heart Disease | Pulmonary Artery Hypertension

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Longitudinal Observational Study of Severe Asthma

Asthma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

Graft vs Host Disease | Graft Rejection | Graft-versus-leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Natural History of Sickle Cell Disease

Pain Crisis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sample Collections From the Airways of Asthmatic Patients

Asthma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Screening for Hematology Branch Protocols

Healthy Volunteer | Hematologic Disease and Disorders | Donors

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cross-sectional Characterization of Idiopathic Bronchiectasis

Respiratory Tract Diseases | Bronchial Diseases | Infection

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease

Cystic Fibrosis | Chronic Granulomatous Disease | Primary Ciliary Dyskinesia | Pseudohypoaldosteronism | Nontuberculous Mycobacterial Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Links Between Inflammation and Cardiometabolic Diseases

Inflammation | Cardiovascular Disease | Diabetes Mellitus | Healthy Volunteer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Natural Killer Cells and Bortezomib to Treat Cancer

Multiple Myeloma | Chronic Myeloid Leukemia (CML) | Pancreatic Ca | Colon/Rectal Ca | Carcinoma, Non-Small -Cell Lung

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)

Myocardial Ischemia | Coronary Artery Disease | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Obesity | Psoriasis | Dyslipidemia | Atherosclerotic Cardiovascular Disease | Cardiometabolic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Leukemia, Lymphocytic, Chronic, B-Cell | Chronic Lymphocytic Leukemia | Leukemia, Chronic Lymphatic | B-Cell Chronic Lymphocytic Leukemia | Leukemia, Lymphocytic, Chronic | B-Lymphocytic Leukemia, Chronic | Leukemia, Chronic Lymphocytic, B-Cell | Lymphocytic Leukemia, Chronic, B Cell | Lymphocytic Leukemia...

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Anemia, Diamond-Blackfan

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

Myeloproliferative Disorders | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Safety and Tolerability | Compare SHINGRIX Vaccine Response Rates

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

Sickle Cell Disease (SCD)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Extended Dosing With Eltrombopag for Severe Aplastic Anemia

Severe Aplastic Anemia (SAA)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Effect of Chronic Inflammation on Myocardial Perfusion and Function

Psoriasis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Eltrombopag for Moderate Aplastic Anemia

Moderate Aplastic Anemia | Unilineage Bone Marrow Failure Disorders

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia

Relapsed Acute Myeloid Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC)

Arterial Calcification | CD73 Deficiency

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2

Hypertension | Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa

Cystic Fibrosis | Pseudomonas Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinical Outcomes and Molecular Phenotypes in Smokers With Parenchymal Lung Disease

Pulmonary Fibrosis | Lung Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease

Graft vs Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Transplantation for Metastatic Solid Tumors

Neoplasm Metastasis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Identification of Genes Expressed in Atherosclerotic Plaque

Atherosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers

Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Chronic Myeloid Leukemia (CML)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure

Aplastic Anemia | Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Cystic Fibrosis | Psuedomas Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Screening for Subjects to Participate in Studies of Blood Disorders

Sickle Cell Disease | Bone Marrow Transplant | G-CSF

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome

Cancer | Muscle Weakness | Skin Fibroblasts

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation

Leukemia, Myeloid, Acute | Leukemia, Lymphoblastic, Acute | Leukemia, Myelocytic, Chronic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients

Thrombocytopenia | Anemia, Aplastic | Anemia, Hypoplastic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation, Treatment, and Training for Patients With Blood Disorders

Hematologic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research Purposes

Bone Marrow Diseases | Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans Syndrome

Bronchiolitis Obliterans | Graft vs Host Disease | Constrictive Bronchiolitis | Bronchiolitis, Exudative | Bronchiolitis, Proliferative

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cytokine Gene Polymorphisms in Bone Marrow Failure

Bone Marrow Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults

Proteomics | Lipoprotein Metabolism | PCSK9

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Alemtuzumab to Treat Severe Aplastic Anemia

Severe Aplastic Anemia, Refractory | Severe Aplastic Anemia, Relapse

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Telomere Repair Gene Mutation in Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States

Clinical Trials Sponsored by Technological Centre of Nutrition and Health

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