Search clinical trials for: [14C] radiolabel

Total 678 results

AstraZeneca
Quotient Sciences

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833

ER-positive, HER2-negative Breast Cancer

United Kingdom
Eli Lilly and Company

Completed

A Study of [¹⁴C]-LY3023414 in Healthy Participants

Healthy

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-BI 409306 After Administration as Oral Solution in Healthy Male Volunteers

Healthy

United Kingdom
Qilu Pharmaceutical Co., Ltd.

Completed

Single Dose Mass Balance Study With [14C]Iruplinalkib (WX-0593) In Healthy Male Volunteers

Healthy

China
Calithera Biosciences, Inc

Withdrawn

A Study to Assess Mass Balance, Pharmacokinetics (PK), and Metabolism of Orally Administered [14 C]-TAK-659 in Participants With Advanced Solid Tumor and/or Lymphoma Malignancies

Advanced Solid Neoplasms | Lymphoma Neoplasms
GlaxoSmithKline

Completed

A Study to Investigate the Recovery, Excretion and Pharmacokinetics of [14C]-GSK2140944 Administered as a Single Intravenous and Single Oral Dose to Healthy Adult Male Subjects

Infections, Respiratory Tract

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate of the Absorption, Metabolism, and Excretion of 14C-JNJ-39823277 in Healthy Male Participants

Healthy

Belgium
H. Lundbeck A/S

Terminated

Safety and Tolerability of Lu AF95245 in Healthy Young Men

Healthy

Netherlands
Pronova BioPharma

Completed

[14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study

Healthy

United Kingdom
Abbisko Therapeutics Co, Ltd

Recruiting

A Mass Balance Study of [14C]ABSK021

Healthy Subjects

China
Daewoong Pharmaceutical Co. LTD.
Shanghai Haini Pharmaceutical Co., Ltd.

Active, not recruiting

A Clinical Study to Investigate the Mass Balance and Biotransformation of [14C]DWP14012 in Healthy Chinese Male Subjects

Phase 1 Study, Healthy Volunteers

China
Allecra

Completed

Single Dose Mass Balance Study With C14 - Labeled AAI101 in Healthy Male Volunteers

Healthy

United States
AstraZeneca
Quotient Sciences

Completed

Absolute Bioavailability and ADME Study of Savolitinib in Healthy Male Subjects

Cancer

United Kingdom
Astellas Pharma Global Development, Inc.

Completed

A Study to Learn How [14C]ASP0367 is Processed by the Body in Healthy Men

Healthy Volunteers

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of Oral Solution of [14C]-BI 201335 in Healthy Male Volunteers

Healthy
Janssen Research & Development, LLC

Completed

A Study of (14C) Radiolabeled JNJ-56136379 in Healthy Male Participants

Healthy

United States
AstraZeneca

Completed

Study to Assess the Absorption, Distribution, Metabolism and Excretion of AZD1656 in Type 2 Diabetes Mellitus (T2DM) (ADME)

Type II Diabetes Mellitus

United States
AbbVie
Genentech, Inc.

Withdrawn

A Pharmacokinetic Study to Access How the Body Absorbs and Removes ABT-199 in Adults With Non-Hodgkin's Lymphoma

Relapsed/Refractory Non-Hodgkin's Lymphoma
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-BIBR 953 ZW After Administration of Single Doses of [14C]-BIBR 953 ZW Intravenously or [14C]-BIBR 1048 Oral Solution in Healthy Male Volunteers

Healthy
Ardea Biosciences, Inc.

Completed

Bioavailability of Lesinurad and Intravenous [14C]Lesinurad

Healthy

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Absorption, Metabolism, and Excretion of JNJ-38518168 After a Single Oral Dose in Healthy Male Participants.

Healthy

Belgium
Bristol-Myers Squibb

Completed

Single Ascending Dose (BMS-813160) Study

Accelerated Intimal Hyperplasia

United States
USDA, Western Human Nutrition Research Center

Completed

Cobalamin Absorption From Fortified Food (FL-72)

Achlorhydria | Vitamin B-12 Deficiency

United States
Pfizer

Completed

A Single-Radiolabeled Dose Mass Balance Study To Investigate The Absorption, Metabolism, And Excretion Of [14C] Palbociclib (PD-0332991) In Healthy Male Volunteers

Healthy

United States
GlaxoSmithKline

Completed

To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]SB-681323 in Healthy Adult Males

Pulmonary Disease, Chronic Obstructive

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
Michael Hoelscher
Leibniz Institute for Natural Product Research and Infection Biology Hans...

Completed

Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment

Lung Diseases | Mycobacterium Infections | Tuberculosis | Tuberculosis, Pulmonary | Bacterial Infections Respiratory

Netherlands
Altavant Sciences GmbH
Covance; Altavant Sciences, Inc.

Completed

Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl

Healthy

United States
Madrigal Pharmaceuticals, Inc.
Worldwide Clinical Trials

Completed

Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196

Healthy

United States
Boehringer Ingelheim

Completed

This Study Tests BI 1467335 in Healthy Male Volunteers. The Study Tests How Different Doses of BI 1467335 Are Taken up and Handled by the Body

Healthy

Netherlands
Sunovion

Completed

RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE

Pharmacokinetics | Metabolism

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

M1774 Human Mass Balance Study (DDRIVER Solid Tumors 303)

Solid Tumor

Hungary
Ganzhou Hemay Pharmaceutical Co., Ltd

Completed

In Vivo Mass Balance Study of [14C]Hemay005

Health Volunteer

China
GlaxoSmithKline

Completed

Study to Investigate the Absorption, Distribution, Metabolism and Elimination of [14C]GSK1120212

Cancer

United States
Epizyme, Inc.

Completed

Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors

Follicular Lymphoma | Marginal Zone Lymphoma | Advanced Solid Tumors | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal Lymphoma

United Kingdom
Genentech, Inc.

Completed

A Pharmacokinetic Study of [14C]-GDC-0810 After Single Oral Administration in Healthy Female Participants

Healthy Volunteers

United States
Galapagos NV

Completed

Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970

Healthy

United Kingdom
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Completed

Anakinra and Kawasaki Disease (KAWAKINRA)

Children | Kawasaki Disease

France
AstraZeneca

Completed

Mass Balance and Metabolic Profiling of [14C]AZD5672 in Healthy Male Volunteers

Rheumatoid Arthritis

United Kingdom
Pfizer

Completed

Single Dose Study With Unlabeled Dose and 14C-labeled Microdose of PF-06700841 in Healthy Male Subjects

Healthy Male Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Single Ascending Dose Study of ACT-541468 in Healthy Male Subjects

Healthy Subjects

Netherlands
H. Lundbeck A/S

Completed

A Study Investigating Tablet Formulations of Lu AF11167 in Healthy Subjects

Healthy

United Kingdom
Bausch Health Americas, Inc.

Completed

Study of the Pharmacokinetics of Intravenous Administered 14C-MNTX

Healthy Male Volunteers

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C] BEA 2180 BR Administered Orally Compared to [14C] BEA 2180 BR Administered Intravenously in Healthy Male Volunteers

Healthy
Pfizer

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]NXL104

Healthy

United Kingdom
Takeda

Completed

TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study

Healthy Volunteers

United Kingdom
AnewPharma

Completed

The Absorption, Metabolism and Excretion of [14C]CM082 in Human

Advanced Solid Tumor

China
F2G Biotech GmbH
PRA Health Sciences

Completed

Absorption, Metabolism and Excretion of 14C-olorofim in Man (hAME)

Invasive Fungal Infections

Netherlands
Onconova Therapeutics, Inc.

Completed

Metabolism and Excretion of [14C]-Rigosertib After Infusion to Volunteers

Healthy

United States

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