Search clinical trials for: Aβ lowering

Total 675 results

Women and Infants Hospital of Rhode Island

Unknown

A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus

Gestational Diabetes

United States
University of California, Los Angeles

Terminated

Field Administration of Stroke Therapy-Blood Pressure Lowering (FAST-BP)

Ischemic Stroke | Intracerebral Hemorrhage

United States
Sun Yat-sen University

Unknown

Lowering-hyperuricemia Treatment on Cardiovascular Outcomes in Peritoneal Dialysis Patients (LUMINA)

Hyperuricemia

China
Rigshospitalet, Denmark

Withdrawn

Vascular Inflammation and Cholesterol Lowering Therapy

Lipid Lowering, Vascular Inflammation

Denmark
Alison Morris

Completed

Statins for Pulmonary and Cardiac Complications of Chronic HIV - Coordinating Center (SPARC)

HIV Seropositivity

United States
Raisio Group

Completed

Lipid-lowering Effect of Plant Stanol Drink

Hypercholesterolemia

Sweden
Chong Kun Dang Pharmaceutical

Completed

A Clinical Trial to Evaluate the Blood Pressure Lowering Effect of a Candemore Plus Tab Versus Cantabell Tab in Hypertensive Patients Inadequately Controlled by Candesartan Monotherapy

Hypertension

Korea, Republic of
Acasti Pharma Inc.

Completed

A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) (TRILOGY 2)

Hypertriglyceridemia

United States, Mexico, Canada
Biogen

Terminated

Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease (PRIME)

Alzheimer's Disease

United States
First Affiliated Hospital of Harbin Medical University

Unknown

Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia

Coronary Artery Disease

China
Catholic University of the Sacred Heart

Completed

Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Italy
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Hypercholesteremia

United States, Canada, Israel
Steno Diabetes Center Copenhagen
University of Copenhagen

Completed

The Effect of Rapid and Slow Glucose Fall on the Subsequent Glucose Production in People With Type 1 Diabetes (RaSlo-19)

Glucose Metabolism Disorders | Type 1 Diabetes | Blood Glucose, Low

Denmark
University of Connecticut

Completed

Health Outcomes of Two Different Tai Chi Interventions

Hypertension | Fall

United States
University Hospital, Montpellier

Completed

Optimizing Statin Tratment in People Living With Diabetes (MEDPHARM-RCV)

Diabetes

France
National Defense Medical Center, Taiwan

Unknown

Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction

Metabolic Syndrome | Hyperuricemia | Left Ventricular Diastolic Dysfunction

Taiwan
Universidad Miguel Hernandez de Elche
Fondo de Investigacion Sanitaria; Fundación para el Fomento de la Investigación... and other collaborators

Completed

Consequences of Doing What Should Not be Done in Primary Care (SOBRINA)

Overdose | Adverse Event

Spain
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Pancreatic Neuroendocrine Carcinoma | Multiple Endocrine Neoplasia Type 1

United States
University of British Columbia

Unknown

Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study) (PLEASe)

Sepsis

Canada
Bayer
Regeneron Pharmaceuticals

Completed

Study to Learn How the Drug Aflibercept Works in in Japanese Patients With Increased Eye Pressure That is Caused by New Blood Vessels Growing in the Eye (Neovascular Glaucoma or NVG). Safety of the Drug and Patients' Tolerability of the Drug Injection is Also Studied (VENERA)

Glaucoma, Neovascular

Japan
Duke University
Sanofi; Regeneron Pharmaceuticals

Completed

Patient and Provider Assessment of Lipid Management Registry (PALM)

Smoking | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Peripheral Arterial Disease | Atherosclerosis | Carotid Stenosis | Hypercholesterolemia | Hyperlipidemia | Claudication | Unstable Angina | Coronary Artery Disease (CAD) | Chronic Kidney Disease (CKD) | Angina | Transient Ischemic Attack (TIA) | Myocardial...

United States
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; European... and other collaborators

Unknown

Lowering InterLeukin-1 Receptor Antagonist Concentrations After TB Treatment Onset (LILAC-TB)

Tuberculosis

Cambodia, Côte D'Ivoire
University of Leicester
University Hospitals, Leicester

Completed

The Impact of Glucose Lowering Therapies on Circulating Endothelial Progenitor Cells and Its Mobilising Factor Stromal Derived Factor-1α in Patients With Type 2 Diabetes (IGLOOS)

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United Kingdom
CirQuest Labs, LLC

Completed

Apixaban + DAPT in Lowering Platelet Reactivity and Thrombin Generation (SEARCH)

Acute Coronary Syndrome

United States
Canadian Heart Research Centre
Amgen

Completed

Guidelines Oriented Approach to Lipid Lowering (GOAL) in Canada (GOAL)

Dyslipidemia
Bionode, LLC

Unknown

Clinical Study Of The Bionode System In Subjects With Elevated IOP

Unmedicated IOP Before and After Treatment

Canada
Alaa Hassan ElBaz

Unknown

Effect of Lipid Lowering Agents on Diabetic Retinopathy and Cardiovascular Risk of Diabetic Patients

Diabetic Retinopathy
Acasti Pharma Inc.

Completed

A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1) (TRILOGY 1)

Hypertriglyceridemia

United States
AstraZeneca

Completed

Intensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria

Type 2 Diabetes | Albuminuria | Hyperuricemia

United States
Boryung Pharmaceutical Co., Ltd

Completed

Fimasartan Blood Pressure Lowering After Acute Stroke (FABULOUS)

Hypertension | Ischemic Stroke | Transient Ischemic Attack

Korea, Republic of
VA Office of Research and Development

Completed

Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II (PREMIER)

Acute Coronary Artery Syndrome

United States
Sonova AG

Completed

Assessment of Novel Sound Changing Principles in Hearing Instruments to Determine Their Application - 2019_04

Hearing Loss

Switzerland
Saint-Joseph University

Unknown

Red Rice Yeast in Low-density Lipoprotein (LDL) Lowering: an Efficacy Study

Dyslipidemias | LDL Hyperlipoproteinemia

Lebanon
Western University, Canada

Unknown

Ketone Supplementation, Glycogen Replenishment and Time Trial Performance Following Glycogen Lowering Exercise

Ketosis | Exercise Performance | Ketonemia

Canada
AstraZeneca

Completed

Epanova® for Lowering Very High Triglycerides II (EVOLVE II) (EVOLVEII)

Hypertriglyceridemia

Denmark, United States, Hungary, Netherlands, Russian Federation, Czechia, Canada
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Lipid-lowering Therapy Individualization

Hypercholesterolemia

Belgium
AstraZeneca
Contract Research Organization: USA; PAREXEL Early Phase Clinical Unit Baltimore and other collaborators

Completed

A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA

Asymptomatic Hyperuricemia

United States
Paracelsus Harz Clinic Bad Suderode.
KKS Netzwerk

Unknown

Lipid Lowering Therapy After Cardiac Rehabilitation LLT-R-Registry (LLT-R-Registry)

Lipid Lowering Therapy After Cardiac Rehabilitation

Germany
Ivantis, Inc.

Completed

Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery

Primary Open Angle Glaucoma | Pseudoexfoliative Glaucoma | Pigmentary Dispersion Glaucoma

United States
Proclara Biosciences, Inc.
Alzheimer's Association

Completed

Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease

Alzheimer Disease

United States
Hue University of Medicine and Pharmacy
Università degli Studi di Sassari

Unknown

Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease Population (VietCKD)

Chronic Kidney Diseases | Hypercholesterolemia

Vietnam
Assistance Publique - Hôpitaux de Paris
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca

Completed

Treat Stroke to Target (TST)

Ischemic Stroke | Transient Ischemic Attack | Atherosclerotic Stenosis

France
VA Office of Research and Development

Completed

Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I (PREMIER)

Acute Coronary Syndrome

United States
GlaxoSmithKline

Completed

To Characterize the Performance of the Nasal Dilator Strip in Lowering Nasal Resistance During Sleep, Promoting Nasal Route Breathing and Reducing the Signs and Symptoms of Sleep Disordered Breathing in a Group of Chronic Nocturnal Nasal Congestion Sufferers Who Report Trouble With Their Sleep.

Sleep Disordered Breathing | Congestion, Nasal

Australia
Prim. Priv. Doz. Dr. Daniel Cejka
Vifor Fresenius Medical Care Renal Pharma

Completed

The Effect of Phosphate Lowering Using Sucroferric Oxyhydroxide (PA21) on Calcification Propensity of Serum

Endstage Renal Disease

Austria
Kansai Electric Power Hospital
Saiseikai Noe Hospital Osaka

Completed

Dietary Impacts on Glucose-lowering Effects of Sitagliptin in Type 2 Diabetes (DIET)

Diabetes Mellitus, Type 2

Japan
University College Cork

Completed

'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure (Saltbreads)

Elevated Blood Pressure

Ireland
Menarini International Operations Luxembourg SA

Completed

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout (FORWARD)

Gout

Poland, Serbia, Germany, Italy, Netherlands, Romania
Amgen

Completed

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2 (RUTHERFORD-2)

Hyperlipidemia

Canada, France, Netherlands, United Kingdom, New Zealand, South Africa, Spain, United States, Australia, Germany, Sweden, Hong Kong, Switzerland, Norway

Search clinical trials for: Aβ lowering

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