Search clinical trials for: Bioavailability in healthy individuals

Total 461188 results

University of Southern Denmark
Rigshospitalet, Denmark; Sygekassernes Helsefond; Bevica Fonden

Completed

"When Movement Moves" - The Health Benefits Among Individuals With Low Physical Mobility Moved by Others (WMM)

Healthy | Physical Disability

Denmark
Edgewise Therapeutics, Inc.

Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Healthy Volunteer

United States
Biogen

Completed

A Study to Evaluate the Relative Bioavailability of Two Formulations of BIIB104 and Assess the Effect of Food on the Pharmacokinetics of BIIB104 Following Administration of a Single, Fixed, Oral Dose of BIIB104 in Healthy Participants

Healthy Volunteers

United States
Allakos Inc.

Completed

A Study to Evaluate Safety, Tolerability, and Bioavailability of Subcutaneous Lirentelimab (AK002) in Adult Healthy Volunteers

Study Conducted in Healthy Volunteers

United States
Biogen
Eisai Co., Ltd.

Completed

A Study to Assess Absolute Bioavailability of Aducanumab in Healthy Volunteers

Healthy Volunteers

United States
Indiana University
Food and Drug Administration (FDA)

Completed

Effects of Altered Formulation on the Bioequivalence of Tacrolimus in Healthy Female and Male Volunteeers (ASDBioequiv)

Bioequivalence

United States
University of California, Davis

Completed

EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations

Healthy Volunteers From Racial/Ethnic Minority Populations

United States
University of Oxford
Oxford Health NHS Foundation Trust; Berkshire Healthcare NHS Foundation Trust

Active, not recruiting

Evaluation of a Rumination Intervention for Individuals With PTSD: A Case Series

Posttraumatic Stress Disorder | Rumination - Thoughts

United Kingdom
São Paulo State University
National Association of Exporters of Citrus Juices; Citrosuco Company

Completed

Effect of Orange Juice and Healthy Diet on Cardiometabolic Risk Factors of Individuals With Metabolic Syndrome

Metabolic Syndrome
Noom Inc.

Completed

Investigation of a Digital Healthy Habits Program for Individuals With Breast Cancer

Obesity | Cancer | Breast Cancer | Overweight | Overweight and Obesity

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
National Institutes of Health Clinical Center (CC)
University of Pennsylvania; University of Virginia

Completed

RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder

Alcohol Dependence | Insomnia | Alcohol Use Disorder

United States
Dr. Anuradha Khadilkar
TATA Trusts

Completed

Study of Vitamin D Fortification of Milk and Oil (Tata)

Healthy Individuals

India
University of Karachi
The Searle Company Limited

Completed

Bioequivalence Study of Rosuvastatin Tablet (BE)

Healthy Individuals

Pakistan
Chong Kun Dang Pharmaceutical

Completed

A Study to Evaluate the Relative Bioavailability of Formulations of CKD-510 and to Assess the Effect of Food on the CKD-510 Tablet Formulation in Healthy Subjects

Healthy Volunteers

United States
Hoffmann-La Roche

Completed

Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Muscular Atrophy, Spinal

United States
University of Bonn
University of Hohenheim

Completed

Plasma Appearance of Xanthohumol in Healthy Adults

Plasmakinetics of Xanthohumol

Germany
Journey Medical Corporation
Dr. Reddy's Laboratories Limited

Completed

A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects

Pharmacokinetics

Canada
BioNTech SE
Pfizer

Completed

Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

COVID-19 | SARS-CoV-2 Infection

United States, Germany, Turkey, South Africa, Argentina, Brazil
Bristol-Myers Squibb

Completed

A Study to Assess Relative Bioavailability of Branebrutinib, From a Tablet Formulation to the Capsule Formulation, the Effect of Food on the Bioavailability of Branebrutinib From a Tablet Formulation, and the Safety and Drug Levels of Branebrutinib From a Tablet Formulation in Healthy Participants

Healthy Volunteers

United States
University Hospital Inselspital, Berne

Withdrawn

Pharmacokinetic Study to Investigate the Bioavailability and Tolerability of 3 Oral Formulations of Sodium Thiosulfate (TSTS)

Healthy
Medical University of Graz

Completed

Humoral and Cellular Immune Response to COVID-19 Vaccines in Immunocompromised and Healthy Individuals (CoVVac)

Covid19 | Immunosuppression

Austria
NeuroSense Therapeutics Ltd.

Completed

A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject

Pharmacokinetics

United States
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
BeiGene

Completed

Relative Bioavailability of Zanubrutinib Tablets Compared to Capsules and Effects of Food on the Pharmacokinetics of the Tablet in Healthy Adults

Healthy Volunteers

United States
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Exploring Learning and Unlearning of Fear

Healthy Individuals

Belgium
GlaxoSmithKline

Completed

A Study to Evaluate Pharmacokinetic, Safety, Tolerability and Relative Bioavailability of Gepotidacin in Healthy Adult Male and Female Participants

Healthy Volunteers

United States
Hasan Kalyoncu University

Active, not recruiting

Does Povidone-Iodine on Nail Affect Pulse Oximeter Reading? (PI)

HEALTHY INDIVIDUALS

Turkey
GlaxoSmithKline

Completed

Comparison of Daprodustat Formulations Produced by Two Methods of Manufacture for Bioequivalence and Dissolution in Healthy Participants

Anaemia

United States
Acasti Pharma Inc.

Active, not recruiting

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

Ataxia Telangiectasia

Canada
Istanbul University

Completed

Effects of Cephalaria Syriaca Flour-added Bread on Glucose Metabolism and Appetite Parameters in Individuals With Obesity, Diabetes, and Healthy Controls.

Nutrition, Healthy

Turkey
Jiangsu HengRui Medicine Co., Ltd.

Completed

Study of Bioavailability, Pharmacodynamics and Safety of SHR-1209 Administered by Single Subcutaneous Injection at Different Sites in Healthy Volunteers

Hypercholesterolemia and Hyperlipidemia

China
Dokuz Eylul University

Completed

Reliability of Elbow Flexion and Extension Strength Measurement Protocols Using a Hand-held Dynamometer

Healthy Individuals

Turkey
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Pamukkale University

Completed

The Effect of Different Head and Trunk Positions on SVV in Healthy Individuals

Virtual Reality

Turkey
Banner Life Sciences LLC

Completed

Comparative Bioavailability of BAFIERTAM™ (Monomethyl Fumarate) and Tecfidera® (Dimethyl Fumarate) in Healthy Subjects

Relapsing Remitting Multiple Sclerosis
Yisheng Biopharma (Singapore) Pte. Ltd.

Completed

A Phase I Study to Evaluate Safety, Tolerability, and Immunogenicity of a PIKA COVID-19 Vaccine in Healthy Individuals

COVID-19 Pandemic

United Arab Emirates
Pfizer

Completed

Relative Bioavailability Study of Nirmatrelvir/Ritonavir 4 Different Fixed Dose Combination Tablets Relative to the Commercial Tablets in Healthy Participants

Healthy Participants | Biological Availability

United States
Galderma R&D

Completed

Study to Access the Relative Bioavailability of Subcutaneous Dose of Nemolizumab When Administered Via Auto-Injector Versus Dual-Chamber Syringe

Healthy Volunteers

United States
Genentech, Inc.

Completed

A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet

Healthy Volunteer

United States
Universidad Nacional Autonoma de Mexico

Completed

Evaluation of the Bioavailability of Dexamethasone in Healthy Subjects

Inflammation | Healthy Subjects | Intravenous Drug Usage | Dexamethasone Administration | Intranasal Administration

Mexico
University of Texas at Austin

Completed

Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals

Intermittent Hypoxia

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Absorption, Metabolism, Excretion, and Absolute Bioavailability of Carbon-14-Labelled [14C] Selpercatinib (LY3527723) in Healthy Male Participants

Healthy

United States
Eisai Limited

Suspended

A Study to Evaluate the Relative Bioavailability of E7386 Following Oral Administration of Targeted Release (TR) Tablets Compared to an E7386 Immediate Release (IR) Tablet in Healthy Adult Participants

Healthy Volunteers

United Kingdom
University of Zurich

Completed

The Effects of Standardized vs Individualized Seat Height on 1-minute Sit-to-stand Performance (ESTI-STS)

Healthy Individuals

Switzerland
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Bioavailability Study of SHR1459 on Healthy Chinese Volunteers

Healthy Adult Subjects

China
Burcu Camcıoğlu Yılmaz

Completed

Acute Effects of Cryotherapy Duration in Healthy Individuals

Cryotherapy Effect

Turkey
AstraZeneca
Parexel

Completed

A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.

Healthy Volunteers

United States
Spanish National Research Council
Andalusian Health Service; Universidad Pablo de Olavide

Completed

Bioavailability of Oleanolic Acid Formulated as Functional Olive Oil (BIO-OLTRAD)

Healthy Subjects | Bioavailability

Spain

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