Search clinical trials for: Bypassing agents

Total 188575 results

Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal
Dr R Viswa Chandra

Recruiting

Assessing the Clinical Efficacy of Hyaluronic Acid Hydrogel in Papilla Augmentation: A Clinical Study.

Gingival Destruction

India
Affiliated Hospital of Jiangnan University

Not yet recruiting

An Exploratory Study of Deep Cervical Lymphovenous Bypass (LVB) in Alzheimer's Disease

Alzheimer Disease
Zhujiang Hospital

Not yet recruiting

Application of Three- Dimensional Visualization Combined With ICG Molecular Fluorescence Imaging in Hepatolithiasis

Hepatectomy | Hepatolithiasis

China
Shandong Provincial Hospital

Not yet recruiting

Henagliflozin's Impact on Prediabetes Remission

Glucose Metabolism Disorders | PreDiabetes | Prediabetic State | Type 2 Diabetes

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Combining Chemoradiotherapy With Sintilimab in First-Line ICC

ICC

China
BioNTech SE

Not yet recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

Small-cell Lung Cancer | Extensive-stage Small-cell Lung Cancer
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
University of Maryland, Baltimore

Not yet recruiting

Effect of RECK in Posterior Spinal Fusion

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Lumbar Spinal Stenosis | Degenerative Disease

United States
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

A Phase 2 Study to Evaluate the Efficacy of the Combination of Cemiplimab and Cetuximab Prior to Salvage Surgery in Patients With Locally Recurrent (Stage 3-5) OCSCC

Locally Recurrent OCSCC

United States
M.D. Anderson Cancer Center
Kura Oncology, Inc.

Not yet recruiting

A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Post Graduate Institute of Medical Education and...

Recruiting

A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary Aspergillosis (NAB-CPA)

Chronic Pulmonary Aspergillosis | Aspergilloma | CPA

India
Bangladesh Institute of Research and Rehabilitation...
Pi Research and Development Center; Acme Laboratories Ltd.

Not yet recruiting

Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh

Type2diabetes

Bangladesh
Universitas Diponegoro
Dr. Kariadi General Hospital Medical Center

Recruiting

Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation (BI-PACED)

Heart Block | Biomarkers | Antibiotic Prophylaxis | CIED Related Infection | CIED-related Infections

Indonesia
Mersin Medicalpark Hastanesi

Recruiting

Does Verapamil Given Orally Prevent Radial Artery Spasm During Transradial Coronary Angiography

Radial Artery Spasm

Turkey
Shandong University
Chinese PLA General Hospital

Not yet recruiting

Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer

Triple Negative Breast Cancer | Sensitivity | Neoadjuvant Immunotherapy
University Hospital, Caen

Recruiting

Alcohol Consumption: Norms, Identities, & Motivations (ALCONIM)

Alcohol Drinking | Binge Drinking

France
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Randomized Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients (ETHNIC)

Acne Vulgaris

France
University Hospital, Lille
Exeliom Biosciences

Not yet recruiting

EXL01 in Combination With Nivolumab for Advanced NSCLC Refractory to Immunotherapy. (EXLIBRIS)

Non-Small Cell Lung Cancer
Sichuan Kelun Pharmaceutical Research Institute...

Recruiting

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
University of Milan
Kolfarma s.r.l. - Italy; Fondazione Telethon

Recruiting

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) (NUTRIENT)

CDKL5

Italy
AstraZeneca

Not yet recruiting

Volrustomig Priming Regimens Exploratory Phase II Platform Study (eVOLVE-01)

Non-small Cell Lung Cancer
Ohio State University Comprehensive Cancer Center

Recruiting

Manipulating E-Cigarette Nicotine to Promote Public Health

Tobacco-Related Carcinoma

United States
The University of Hong Kong

Not yet recruiting

Evaluation of Efficacy and Safety of Enhanced External Counter-pulsation on Patients With Atopic Dermatitis and Inflammatory Skin Disease Requiring Wet Wrap Therapy

Atopic Dermatitis | Inflammatory Skin Disease
Chimei Medical Center
E-DA Hospital

Not yet recruiting

Clinical Outcomes Of Mega-dosage Supplementations Of Cholecalciferol In Critically Ill Patients With Sepsis (MDC-S)

Sepsis | Critically Ill | Critical Care | Mortality Rate
Shanghai Zhongshan Hospital

Not yet recruiting

Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients

Analgesia | Mechanical Ventilation | Remifentanil | Postoperative | Oxycodone

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-M07D1, BL-M07D1+Pertuzumab and BL-M07D1+Pertuzumab+Docetaxel in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer

HER2-positive Breast Cancer

China
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP

Chronic Kidney Diseases | Apical Periodontitis

India
Connecticut Children's Medical Center

Not yet recruiting

Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure

Respiratory Distress Syndrome, Newborn | Intensive Care Units, Neonatal | Pulmonary Surfactants
Ohio State University
Patient-Centered Outcomes Research Institute; The George Washington University...

Not yet recruiting

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes (DECIDE)

Pregnancy, High Risk | Gestational Diabetes Mellitus

United States
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
The University of Texas Health Science Center at...
Baptist Health Foundation of San Antonio

Recruiting

Prevention of Progression of Prediabetes, Obesity and CV Risk (Pre-DM)

Cardiovascular Diseases | Weight, Body | Pre-Diabetes

United States
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

SMARCB1-Deficient Malignancies

United States
Anhui Provincial Hospital

Not yet recruiting

SV2A-PET/CT and PET/MRI Combined Clinical Criteria Score in the Diagnosis of Early Cognitive Alteration

Alzheimer Disease
Zachary Zumsteg

Not yet recruiting

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

Carcinoma | Oropharyngeal Cancer

United States
National University Hospital, Singapore
National Medical Research Council (NMRC), Singapore

Not yet recruiting

Adjunctive Doxycycline for Central Nervous System Tuberculosis (DIRECT)

Tuberculosis, Meningeal | Tuberculosis, Central Nervous System | Tuberculosis; Meningitis (Etiology) | Tuberculosis; Meningoencephalitis (Etiology)

Singapore
Sichuan University

Not yet recruiting

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Dr. George Luciuk

Recruiting

Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral Challenges

Hypersensitivity | Anaphylaxis

Canada
Uppsala University
Sahlgrenska University Hospital, Sweden; University Hospital, Umeå; Uppsala University... and other collaborators

Not yet recruiting

The Case of "Triple" Versus "Double" Therapy for Patients With High Volume Metastatic Hormone Sensitive Prostate Cancer (Lead4Care)

Prostate Cancer

Sweden
Mongi Slim Hospital

Recruiting

Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia (OPDPH)

Post-Dural Puncture Headache

Tunisia
The First Hospital of Jilin University

Not yet recruiting

Adebrelimab Plus Chemotherapy, Bevacizumab and Fluzoparib in Platinum-Sensitive Relapsed Ovarian Cancer

Platinum-sensitive Relapsed Ovarian Cancer
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors

Advanced Solid Tumor

China
Institut National de la Santé Et de la Recherche...

Recruiting

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain (APEDOC)

Stroke

France
Chang Gung Memorial Hospital

Not yet recruiting

Magnesium Sulfate Combined With Intraarticular Cocktail Injection for Analgesia After Simultaneous Bilateral Total Knee Arthroplasty

Osteoarthritis, Knee
Ball State University

Recruiting

The Movie Theater Study

Hyperinsulinemia | Hyperglycemia, Postprandial

United States
Uppsala University Hospital
Norrlands Universitetssjukhus, Umea, Sweden

Recruiting

Early Detection of Relapse in Ovarian Cancer Using Capillary Home-sampling and a Protein Biomarker Test (FOLL-OV)

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

Sweden
Rong Tao
Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

Recruiting

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

Acute Lymphoblastic Leukemia, in Relapse | B-cell Lymphoma Refractory | B-cell Lymphoma Recurrent | Acute Lymphoblastic Leukemia With Failed Remission

China
Institute of Hematology & Blood Diseases Hospital...

Recruiting

VMAC+DLI Treatment of Patients With Relapse of AML After Allo-HSCT (VMAC+DLI)

Relapse Acute Myeloid Leukemia

China

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