Search clinical trials for: Drug Interactions

Total 259015 results

Max Zeller Soehne AG

Unknown

Drug Cocktail Interaction Study of St. John's Wort Dry Extract Ze 117

Drug Interaction Study

Germany
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Drug-drug Interactions Between Darunavir/Cobicistat and Etravirine in Hiv- Infected Patients

HIV-1 Infection

Spain
Sony Tuteja
American College of Clinical Pharmacy

Completed

Pharmacogenetics to Predict Drug Interactions in Kidney Transplant Recipients

Kidney Transplantation

United States
Vanderbilt University

Completed

Autonomic Nervous System and Nitric Oxide Interactions

Endothelial Dysfunction

United States
Aegerion Pharmaceuticals, Inc.

Completed

Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents

Healthy

United States
Corcept Therapeutics

Completed

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Healthy | Drug Interaction Potentiation

United States
Centre Hospitalier Universitaire de Nice

Terminated

Analysis of Osteoimmune Interactions Linking Inflammation and Bone Destruction in Aggressive Periodontitis (PAG)

Aggressive Periodontitis | Chronic Periodontitis

France
University Hospital, Caen

Completed

Older HIV-infected Adults and Drug Interactions: French Cross-sectional Study (POPVIH65)

HIV Infections
Boryung Pharmaceutical Co., Ltd

Completed

A Clinical Trial to Evaluate Pharmacokinetic Interactions and Safety Between Fimasartan and Linagliptin in Healthy Male Volunteers

Hypertension

Korea, Republic of
GlaxoSmithKline

Completed

Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation

Drug Interactions

Korea, Republic of
LEO Pharma

Completed

Open-label, Single Center, Non-randomized, Fixed Sequence Phase 1 Drug-drug Interaction Study With LEO 32731 and Midazolam

Drug Interaction Potentiation

Germany
GlaxoSmithKline

Completed

A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors

Cancer

Australia, United States, United Kingdom
F2G Biotech GmbH
Bio-Kinetic Europe, Ltd.

Withdrawn

Drug/Drug Interactions With F901318

Invasive Aspergillosis
University of Washington
Bastyr University

Completed

Resveratrol and Midazolam Metabolism

Healthy

United States
BioCryst Pharmaceuticals

Completed

A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions

Hereditary Angioedema

United Kingdom
University of Pisa

Unknown

Prospective Study of VEGFR-2 /IL-8 Genetic Interaction in MBC Treated With Paclitaxel and Bevacizumab vs. Chemotherapy (BEVAPROS)

Metastatic Breast Cancer

Italy
McMaster University
Lallemand Health Solutions

Completed

Study on the Effects of a Probiotic on Autonomic and Psychological Stress

Stress, Psychological

Canada
Biogen

Completed

Study to Evaluate the Interaction Between a Drug and CNV1014802 in Healthy Subjects

Healthy

United Kingdom
Stendhal Americas, S.A.
LG Chem; Universidad Nacional Autonoma de Mexico

Completed

An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers

Diabetes Mellitus, Type 2

Mexico
Indiana University
National Institute of General Medical Sciences (NIGMS)

Completed

CYP2B6 Genetics and Drug Interactions in Healthy Volunteers

Healthy

United States
Verifomics LLC

Terminated

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

Obesity | Arthritis | Arthralgia | Migraine Disorders | Sleep Initiation and Maintenance Disorders | Anxiety | Rhinitis | Rhinitis, Allergic | Respiratory Sounds | Headache | Sleep Deprivation | Dyspnea

United States
AbbVie
Boehringer Ingelheim

Completed

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Psoriasis

Germany
Collegium Medicum w Bydgoszczy

Completed

Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction (IMPRESSION)

ST-segment Elevation Myocardial Infarction | Non-ST-segment Elevation Myocardial Infarction | VA Drug Interactions

Poland
HK inno.N Corporation

Completed

Pharmacokinetic Interactions Between Amlodipine Besylate/Valsartan and Atorvastatin in Healthy Male Subjects

Healthy

Korea, Republic of
SK Life Science, Inc.

Completed

Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs as a Means of Predicting Drug-drug Interactions

Healthy

United States
National Institutes of Health Clinical Center (CC)

Completed

Pharmacokinetic Interactions With Prednisolone in Healthy Volunteers and HIV-infected Patients Receiving Single-Dose Prednisone

Healthy

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How Daily Dosing With Enzalutamide Affects the Metabolism of Caffeine and Dextromethorphan in Men With Prostate Cancer

Prostate Cancer | Pharmacokinetics of Dextromethorphan | Pharmacokinetics of Caffeine

Moldova, Republic of
Hospital General Universitario Gregorio Marañon
Merck Sharp & Dohme LLC; SERMAS; Molecular-Clinical Pharmacol/Instit.Translational...

Unknown

Polypharmacy and Clinically Significant Drug Interactions Among HIV-Infected Patients Receiving Antiretroviral Therapy (PODIUM)

HIV
Gerd Mikus

Completed

Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Drug Interactions

Germany
Gerd Mikus

Completed

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Drug Interactions

Germany
Yale University
National Institute on Drug Abuse (NIDA); VA Office of Research and Development

Completed

Dronabinol Interactions With Cognitive Enhancing Drug in Humans

Marijuana Abuse | Cannabis

United States
Sunnybrook Health Sciences Centre

Completed

The Role of Cytokine-Serotonin Interactions in Post-Stroke Depression

Depression

Canada
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Yuyu Pharma, Inc.

Completed

A Study to Investigate the Pharmacokinetic Drug Interactions Between Dutasteride and Tadalafil in Healthy Male Subjects

Benign Prostate Hyperplasia
Susan Smyth

Completed

Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions

Acute Coronary Syndrome | Angioplasty, Transluminal, Percutaneous Coronary | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Blood Platelets

United States
Medical University of Vienna

Completed

Drug Drug Interactions of Aspirin and P2Y12-inhibitors

Myocardial Infarction | Drug Interaction Potentiation

Austria
Genelex Corporation
University of Utah

Completed

YouScript IMPACT Registry (IMPACT)

Drug Interaction Potentiation | Adverse Drug Events | Adverse Drug Reactions | Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant | Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 Enzyme Deficiency | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome... and other conditions

United States
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Study to Explore Drug-drug Interactions Between DWC20155 and DWC20156 in Healthy Subjects

Healthy

Korea, Republic of
West Virginia University
West Virginia Clinical and Translational Science Institute

Terminated

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

Cancer of Head and Neck

United States
University Hospital, Geneva

Completed

Dose Adaptation to Offset the Interaction Between Ticagrelor and Ritonavir by Population-based PK Modeling

Healthy

Switzerland
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
Il-Yang Pharm. Co., Ltd.
Severance Hospital

Completed

Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Clarithromycin, Amoxicillin and Ilaprazole (DDI)

Drug Interaction Potentiation

Korea, Republic of
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

Cocaine-Related Disorders

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)

Methamphetamine Dependence | Methamphetamine Abuse

United States, Canada
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Terminated

Interactions Between Intravenous (IV) Cocaine and Lofexidine

Cocaine Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Cocaine and Tolcapone - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1

Amphetamine-Related Disorders

United States

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