Search clinical trials for: Drug interactions (Cytochrome P450 and p-glycoprotein)

Total 472642 results

Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Drug-drug Interaction Study of FYU-981 and Oxaprozin

Healthy

Japan
University Hospital Inselspital, Berne

Completed

Studying the Starvation Effect on Androgen Metabolism in 20 Healthy Young Women and Comparison to Women With PCOS. (SEA)

PCOS Disease

Switzerland
AbbVie

Completed

A Study to Evaluate the Effect of Intravenous (IV) Infusions of Risankizumab on Pharmacokinetics of Cytochome P450 Substrates in Adult Participants With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis (UC)

United States, Germany, Israel
Hospital de Mataró

Unknown

The Effect of Beta-blockers in Substance P Levels and the Swallowing Function (BETASP)

Swallowing Disorder | Beta Blockers | Substance P

Spain
Weill Medical College of Cornell University
Bristol-Myers Squibb

Terminated

Dasatinib in Polycythemia Vera

Polycythemia Vera

United States
Seattle Children's Research Institute (SCRI)

Completed

Malaria Challenge in Healthy Volunteers (ITV)

Malaria

United States
University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Brigham... and other collaborators

Completed

Gut Microbiome and p-Inulin in Hemodialysis

End-Stage Renal Disease | Gut Microbiome Dysbiosis

United States
Chiesi Farmaceutici S.p.A.

Completed

A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® (CT03Ext)

Cystic Fibrosis

Ukraine, France, Poland
University of Bern

Completed

Overcoming Psychomotor Slowing in Psychosis (OCoPS-P) (OCoPS-P)

Schizophrenia | Schizoaffective Disorder | Schizophrenia and Related Disorders | Brief Psychotic Disorder

Switzerland
Seattle Children's Hospital
Doris Duke Charitable Foundation

Completed

Triple P With Pediatric Residents

Parenting | Psychosocial Problem | Problematic Behavior in Children
Chauhan, Suneet P., M.D.

Unknown

Hydration and Rate of Cesarean Delivery Among Nulliparous

Pregnancy

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

Alzheimer Disease

Belgium
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics

Drug Metabolism Phenotype

United States
National Institutes of Health Clinical Center (CC)

Completed

Differences in Blood Levels of Nevirapine in HIV-infected Patients in Uganda and the United States

HIV Infection

United States, Uganda
Abant Izzet Baysal University

Completed

Evaluation of the Effect of 10% Lidocaine Spray Undergoing Coronary Artery Bypass Graft Operation (ELCABG)

Cardiovascular Diseases | Tracheal Intubation Morbidity | Lidocaine Causing Adverse Effects in Therapeutic Use

Turkey
Diskapi Teaching and Research Hospital

Completed

Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration

Benign Prostate Hyperplasia

Turkey
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL (PET)

Depression

Sweden
Shanghai Mental Health Center

Recruiting

Reliability and Validity of FIBSER, STAR-P, HEA Scale The Reliability and Validity of Chinese Version of FIBSER, STAR-P, HEA Scale in Depression Assessment

Depression

China
Kevin F. Gibson
University of Pittsburgh

Terminated

Impact of Chemokine Receptor 5 (CCR5) Inhibition on Sarcoidosis Immunophenotypes (GRADS)

Sarcoidosis

United States
Sarcoma Oncology Research Center, LLC

Recruiting

Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Leiomyosarcoma (TAGGED)

Leiomyosarcoma

United States
Pfizer

Completed

Investigation Of Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Single Doses Of Vupanorsen In Japanese Healthy Adult Participants With Elevated Triglycerides

Healthy

Japan
Shionogi

Completed

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

Healthy Volunteer

United States, Japan
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Co-artemether in Non-immune Travelers

Acute Uncomplicated P. Falciparum Malaria
Ruijin Hospital
Chongqing Kingbiotech Co.,Ltd

Recruiting

In Vitro Organoid Drug Sensitivity-Guided Treatment for Advanced Pancreatic Neuroendocrine Tumor

Advanced Pancreatic Neuroendocrine Tumor

China
Mahidol University

Unknown

Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand

Acute Uncomplicated Malaria With P.Vivax Infection

Thailand
Mayo Clinic
Roche Pharma AG

Completed

CellCept in p-ANCA Vasculitis

Microscopic Polyangiitis | MPO-ANCA Vasculitis

United States
Croma-Pharma GmbH
Proinnovera GmbH

Not yet recruiting

THIODERM ELATE for Volume Augmentation in Lips (TIVOLI)

Lip; Anomaly

Austria
Croma-Pharma GmbH
Proinnovera GmbH

Active, not recruiting

THIODERM ELATE for Augmentation of Very Thin, Thin, and Moderately Thick Lips (TILI)

Lip Abnormality

Austria
Carebot s.r.o.

Completed

Retrospective Study of Carebot AI CXR Performance in Preclinical Practice

Pneumonia | Lung Diseases | Pneumothorax | Lung Cancer | Cardiomegaly | Artificial Intelligence | Pulmonary Edema | Pleural Effusion | Atelectasis | Consolidation | Hilar Calcification | Fracture Rib

Czechia
Federal University of Uberlandia

Completed

Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women

Sarcopenia

Brazil
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Albert...

Not yet recruiting

Dexamethasone/Pancreatic Clamp P&F

Insulin Resistance | Prediabetic State | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

United States
Armed Forces Research Institute of Medical Sciences...
University of North Carolina, Chapel Hill

Recruiting

Biomarkers of P. Vivax Relapse

Malaria | Vivax Malaria | Relapse | CYP2D6 Polymorphism

Thailand
Biotronik (Beijing) Medical Device Ltd.

Completed

BIOLUX P-IV CHINA ( BIOTRONIK )

Peripheral Arterial Disease

China
The HIV Netherlands Australia Thailand Research...
University of California, San Francisco; amfAR, The Foundation for AIDS Research and other collaborators

Completed

Second-line Therapy (TASER-P)

Treatment Failure of Second-line ART in Asian HIV-infected Children

Thailand, Malaysia, Indonesia, Vietnam
University Hospital, Basel, Switzerland

Completed

In Vivo Determination of Cytochrome P450 Activities in Patients With Liver Cirrhosis (CombiCapsLC)

Liver Cirrhosis

Switzerland
Menarini International Operations Luxembourg SA

Recruiting

Open-label, Multicenter, multinAtionaL, inteRventional Clinical Trial to Assess Efficacy and Safety of the exteMporaneous combInation of Nebivolol and Ramipril in hypertenSIve pAtients (ARTEMISIA)

Hypertension

Hungary
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Clinical Pharmacology of FYU-981 (Final Formulation)

Healthy

Japan
Remko P. Bosgraaf

Completed

Evaluate Formation of IUAs After Third-generation Endometrial Ablation, With and Without Intrauterine Adhesion Barrier (CLEAN)

Asherman Syndrome | Intrauterine Adhesion

Netherlands
J P Lecoq

Completed

Local Anesthetic Automated Intermittent Administration vs. Continuous Infusion Via Femoral Nerve Block.

Postoperative Complications | Postoperative Pain

Belgium
Bennett, James P., Jr., M.D., Ph.D.

Completed

R(+)PPX High Dose Treatment of ALS

Amyotrophic Lateral Sclerosis

United States
Markus Joerger
University of Basel

Completed

Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer Patients

Non Small-cell Lung Cancer | Renal-cell Cancer | Gastrointestinal Stroma Tumor

Switzerland
NEMA Research, Inc.

Completed

Exposure to Potential Cytochrome P450 Pharmacokinetic Drug-Drug Interactions Among Osteoarthritis Patients: Incremental Risk of Multiple Prescriptions

Chronic Low Back Pain
Bispebjerg Hospital

Completed

Ultrasound-guided Nerve Blocks for the Sciatic and Saphenous Nerves: Characteristics of the Single Penetration Dual Injection (SPEDI) Technique

Lower Leg Surgery, e.g. Ankle Fractures

Denmark
NEMA Research, Inc.

Completed

Cytochrome P450 Pharmacokinetic DDIs Among Patients With Chronic Low Back Pain Taking Opioids

Chronic Low Back Pain
National Institute of Allergy and Infectious Diseases...

Completed

Experimental Vaccine for Prevention of Ebola Virus Infection

Ebola Virus Disease | Ebola Hemorrhagic Fever | Ebola Virus Vaccines | Envelope Glycoprotein, Ebola Virus | Filovirus

United States
Universitaire Ziekenhuizen KU Leuven

Terminated

The Effect of Antimicrobial Therapy on the Serum Level of P-cresol in Peritoneal Dialysis Patients

Chronic Kidney Disease

Belgium
Chiesi Farmaceutici S.p.A.

Completed

A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI® (CT03 Core)

Cystic Fibrosis

Spain, Ukraine, Czechia, France, Germany, Hungary, Poland, Russian Federation
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S (MAL019)

Malaria, Falciparum

United States
Drug Induced Liver Disease Study Group

Unknown

A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P） (DILI-P)

Drug-induced Liver Injury

China
McMaster University

Not yet recruiting

REduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial (REPOURT-P)

Thoracic Surgery | Thoracic Epidural Analgesia | Urinary Catheterization

Search clinical trials for: Drug interactions (Cytochrome P450 and p-glycoprotein)

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