Search clinical trials for: Esomeprazole

Total 453 results

AstraZeneca

Completed

Efficacy of Esomeprazole in Patients With Frequent Heartburn (NEXT1)

Heartburn

United States
Walter Reed Army Medical Center

Completed

Fluticasone Versus Esomeprazole to Treat Eosinophilic Esophagitis

Eosinophilic Esophagitis

United States
University of Florida
AstraZeneca

Terminated

Viokase 16, Viokase16 Plus Nexium and Nexium Alone (AZ)

Chronic Pancreatitis

United States
AstraZeneca
Parexel

Completed

To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Gastroesophageal Reflux Disease | GERD | Reflux Esophagitis
Seoul National University Bundang Hospital

Completed

Long-term Follow up Helicobacter Pylori Reinfection Rate After Second-Line Treatment: Bismuth-Containing Quadruple Therapy Versus Moxifloxacin-Based Triple Therapy

Helicobacter Infections

Korea, Republic of
American University of Beirut Medical Center
AstraZeneca

Completed

The Effect of Proton Pump Inhibitors on Calcium and Bone Metabolism

Calcium Metabolism Disorders

Lebanon
Walter Reed National Military Medical Center

Completed

Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor Therapy

GERD
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.

GERD Without Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
AstraZeneca

Completed

Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects

Healthy

United States
AstraZeneca

Completed

A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis.

GERD With Erosive Esophagitis

Sweden, United States, France, Italy, United Kingdom, Germany, Denmark, Finland, Norway, Canada
The University of Hong Kong

Completed

Quadruple Versus Sequential Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori Infection

Hong Kong
Johns Hopkins Bloomberg School of Public Health
National Heart, Lung, and Blood Institute (NHLBI); American Lung Association...

Completed

Study of Acid Reflux in Asthma

Lung Diseases | Lung Diseases, Obstructive | Asthma

United States
City of Hope Medical Center

Completed

Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers

Healthy

United States
AstraZeneca

Completed

Bioequivalence Study Comparing D961H Sachet and D961H Capsule in Japanese Healthy Male Subjects

Bioequivalence Study

Japan
AstraZeneca

Completed

Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients (MAESTRO)

GERD

France
AstraZeneca

Completed

Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose Aspirin

Prevention

Korea, Republic of, Japan, Taiwan
AstraZeneca
Quintiles, Inc.

Completed

To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Heartburn

China
AstraZeneca

Completed

A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI) (NEON)

Gastroesophageal Reflux Disease

Chile, Argentina, Venezuela, Colombia
AstraZeneca

Completed

Esomeprazole Treatment Co-diagnosed Non Erosive Reflux Disease (NERD) and Chronic Gastritis Patients

Chronic Gastritis | Non Erosive Reflux Disease

China
AstraZeneca

Completed

Long Term Study to Investigate the Efficacy & Safety of D961H (Esomeprazole) for the Prevention of NSAIDs-induced Ulcer

Osteoarthritis | Rheumatoid Arthritis | Lumbago | Gastric Ulcer | Duodenal Ulcer

Japan
Lise Tarnow
Novo Nordisk A/S; Steno Diabetes Center Copenhagen; Chr Hansen; Statens Serum Institut

Completed

The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes (Nexium)

Type 2 Diabetes
Chinese University of Hong Kong

Terminated

A Comparison of Gastric pH Control With High Dose Intravenous or Oral Esomeprazole

Gastrointestinal Hemorrhage

China
AstraZeneca

Completed

Esomeprazole (NEXIUM) vs. Surgery (LOTUS)

Gastroesophageal Reflux

Italy, Sweden, Germany, Denmark, Finland, Norway, Netherlands, Austria, Belgium, United Kingdom, France, Iceland
Vecta Ltd.

Completed

Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms

Gastroesophageal Reflux

United States
Yuhan Corporation

Completed

Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects

Healthy

Korea, Republic of
AstraZeneca

Completed

Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on Low Dose Acetylsalicylic Acid (LDA) (Oberon)

Gastric Ulcer | Duodenal Ulcer

United States, Bulgaria, Czech Republic, Korea, Republic of, Russian Federation, South Africa, Philippines, Poland, Romania, Finland, Norway, Canada, Mexico, Argentina, Australia, Germany, Portugal, Slovakia, Thailand, Indonesia
Takeda

Completed

Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease (PAMES 0109)

GERD

Brazil
AstraZeneca

Completed

Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers

Juvenile Idiopathic Arthritis

United States
Ruttonjee Hospital
Queen Mary Hospital, Hong Kong

Unknown

Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia

Dyspepsia | Aspirin

China
Ruttonjee Hospital

Completed

Prevention of Gastrointestinal Bleeding in Patients With Severe Ischemic Heart Disease

Acute Coronary Syndrome | Acute Myocardial Infarction

China
Pfizer

Completed

Drug Drug Interaction Study Of Crizotinib With Esomeprazole.

Healthy

Belgium
GlaxoSmithKline

Completed

VEG113971: An Open-Label Study of the Effects of Ketoconazole or Esomeprazole on Pazopanib PK

Cancer

United States
AstraZeneca

Completed

A Healthy Female and Male Volunteers Aspirin Study

Healthy

United Kingdom
Massachusetts General Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Different Vitamin D Preparations & FGF23 in Humans

Vitamin D Deficiency

United States
AstraZeneca

Completed

Study to Assess the Bioequivalence Between D961S and Esomeprazole/Buffered Acetylsalicylic Acid (ASA) in Japanese Healthy Male Subjects

Bioequivalence Study

Japan
Göteborg University

Completed

Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer Patients

Colorectal Cancer

Sweden
University of Campania "Luigi Vanvitelli"

Completed

5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori Infection

Helicobacter Pylori Infection

Italy
Forest Laboratories

Completed

The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.

Dyspepsia

United States
David A. Johnson, MD
AstraZeneca

Completed

Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance

GERD

United States
Centre de Recherche de l'Institut Universitaire...

Completed

Evaluation of the Influence of Statins and Proton Pump Inhibitors on Clopidogrel Antiplatelet Effects (SPICE)

Coronary Artery Disease

Canada
Takeda

Completed

A Study of the Effects of Multiple Doses of Dexlansoprazole, Lansoprazole, Omeprazole or Esomeprazole on the Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Participants.

Healthy

United States
AstraZeneca

Terminated

Study Comparing Esomeprazole and ASA Combined Together as One Capsule Versus These Medications Taken Separately

Peptic Ulcer Disease

Canada
University of North Carolina, Chapel Hill
AstraZeneca

Completed

The Utility of Nexium in Chronic Cough and Reflux Disease

Cough | GERD

United States
Mayo Clinic
AstraZeneca

Completed

Which Supraesophageal Reflux Symptoms Reliably Respond to Proton-Pump-Inhibitor (PPI) Therapy

Gastroesophageal Reflux

United States
HSK Wiesbaden

Terminated

APE-Study: Ablation of Barrett's Mucosa vs. Surveillance Without Ablation in Patients Cured From Barrett's Cancer Combined With Randomization of Esomeprazole vs. Placebo for Symptomatic Reflux Control After Successful Barrett's Ablation (APE)

Barrett's Esophagus

Germany
AstraZeneca

Completed

A Bioequivalence Study to Compare VIMOVO Manufactured at AstraZenca AB to VIMOVO Manufactured by Patheon Pharmaceuticals and Marketed Enteric-coated Naproxen Formulation

Healthy Volunteers | Bioequivalence

United Kingdom
AstraZeneca

Completed

An Interaction Study to Evaluate the Effect of Esomeprazole/Acetylsalicylic Acid on the Metabolism and Effect of Clopidogrel

Healthy Volunteers

Sweden
Otsuka Pharmaceutical, Inc., Philippines

Completed

Randomized Double-Blind Clinical Trial of Rebamipide vs Esomeprazole in the Treatment of NSAID-induced Gastropathy

NSAID Induced Gastropathy

Philippines
Taipei Medical University

Unknown

A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy

Upper Gastrointestinal Bleeding

Taiwan
Norwegian University of Science and Technology
Ferrosan AS

Completed

On Demand Treatment of Reflux Disease

Gastroesophageal Reflux

Norway

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