Search clinical trials for: Gene Fusions

Total 271070 results

Hoffmann-La Roche

Withdrawn

ESP Study: A Study to Assess the Effect of Adding Fuzeon (Enfuvirtide) to an Antiretroviral Regimen in Fuzeon-Naive Patients With Sustained HIV Viral Suppression.

HIV Infections

Australia
Hoffmann-La Roche
Trimeris

Completed

BLQ Study: A Study of a Protease Inhibitor With Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With HIV-1.

HIV Infections

United States, Australia
Jiao Mingfei

Unknown

Intravitreal Conbercept for Idiopathic Choroidal Neovascularization

Idiopathic Choroidal Neovascularization

China
CytoDyn, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

PRO 140 by IV Administration in Adults With HIV-1 Infection

HIV Infections

United States
ANRS, Emerging Infectious Diseases
Pfizer

Completed

Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients (OPTIMAL)

HIV-1 Infection | AIDS

France
Hoffmann-La Roche

Completed

A Study of Enfuvirtide (Fuzeon) in Participants With Advanced Human Immunodeficiency Virus (HIV) Infection

HIV Infections

Thailand
ViiV Healthcare

Completed

Expanded Access Program for Maraviroc At Multiple Centers

HIV Infections

Canada, United States, Spain, Switzerland, Malaysia, France, Italy, Portugal, Puerto Rico, Mexico, Australia, Ireland, Romania, Greece, United Kingdom, Argentina, Austria, Belgium, Chile, Costa Rica, Dominican Republic, Germany, Hong... and more
Affiliated Hospital to Academy of Military Medical...

Unknown

Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantation

Hematopoietic Stem Cell Transplantation | Graft-versus-host Disease

China
Sanofi
Regeneron Pharmaceuticals

Completed

Study of AVE0005 (VEGF Trap) in Patients With Chemoresistant Advanced Ovarian Cancer

Neoplasms | Cancer of the Ovary

United States, France, Canada, Australia, Germany, Italy, Netherlands, Portugal, Spain, Sweden, Switzerland
CSL Behring

Completed

A Safety and Efficacy Study of a Recombinant Factor IX in Patients With Severe Hemophilia B

Hemophilia B

Bulgaria, Israel
ViiV Healthcare
Pfizer

Withdrawn

Maraviroc Compassionate Use

Human Immunodeficiency Virus Type 1
University of Aarhus
Aarhus University Hospital; AP Moeller Foundation; Bendtsen, Thomas Fichtner,...

Completed

Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block

Pain, Postoperative | Anesthesia, Local | Hip Fractures
Hoffmann-La Roche

Completed

Efficacy, and Safety Study of Optimized Background Antiretroviral Regimen (OB) in Combination With Enfuvirtide in the Treatment-Experienced Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection

HIV Infections

France
University of Toronto
Unity Health Toronto; Maple Leaf Research

Completed

Effects of Intensive cART During Acute/Early HIV Infection

Acute HIV Infection

Canada
Hoffmann-La Roche
Trimeris

Completed

T-20 Plus a Selected Anti-HIV Treatment in HIV-Infected Children and Adolescents

HIV Infections

United States
Catholic University of the Sacred Heart

Terminated

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA) (GUSTA)

HIV Infection

Italy
Kirby Institute

Completed

MARCH Renal Substudy (MARCHrenal)

Proteinuria | HIV

Canada, Australia, Germany, Argentina, Japan, Thailand, United Kingdom, Mexico
Kirby Institute

Completed

MARCH Vascular Endothelium Substudy (MARCH VE)

Cardiovascular Disease

Argentina, Australia, Germany, Thailand
Kirby Institute
Pfizer; ViiV Healthcare

Completed

Maraviroc Switch Collaborative Study (MARCH)

HIV

Spain, Australia, Ireland, Mexico, Germany, Argentina, Canada, Chile, France, Japan, Poland, Thailand, United Kingdom
Kirby Institute

Completed

MARCH Central Nervous System Substudy

HIV-1 Infection

Argentina, Thailand, United Kingdom
ViiV Healthcare
Pfizer

Terminated

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 (MODERN)

HIV-1

United States, Netherlands, Spain, Puerto Rico, Canada, Australia, Germany, Sweden, Poland, Portugal, Switzerland, France, Denmark, Italy, Belgium, United Kingdom, Hungary, Austria, Finland
CytoDyn, Inc.

Completed

Study of PRO 140 by Subcutaneous Administration in Adult Subjects With HIV -1 Infection

HIV Infections | HIV -1 Infection

United States
Fundacion para la Investigacion Biomedica del Hospital...

Terminated

Effect of Cytoreductive Chemotherapy and a CCR5 Coreceptor Antagonist on HIV-1 Eradication (CHEMOMAR)

HIV-1 Infection

Spain
Washington University School of Medicine

Withdrawn

Ponatinib in the Treatment of FGFR Mutation Positive Recurrent or Persistent Endometrial Carcinoma

Endometrial Neoplasms
Hoffmann-La Roche
Trimeris

Completed

WAND Study - A Study to Evaluate Fuzeon (Enfuvirtide) Administered by a Needle-Free Injection Device in Patients With HIV.

HIV Infections

United States
Hoffmann-La Roche
Trimeris

Completed

BOSS Study: A Study of Fuzeon Using the Needle-Free Biojector 2000 in Patients With HIV-1 Infection

HIV Infections

United States, Puerto Rico
International Partnership for Microbicides, Inc.

Completed

Safety and Pharmacokinetics of Dapivirine/Maraviroc Vaginal Ring

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety and Efficacy of Adding Enfuvirtide to Oral Highly Active Antiretroviral Therapy (HAART) in Human Immunodeficiency Virus (HIV) Patients With Prior Treatment Experience (INTENSE)

HIV Infections

France, Germany, Spain, Italy, United States, Switzerland, Netherlands, Mexico, Canada, Israel
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults

HIV Infections

United States, Puerto Rico
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; ViiV Healthcare

Terminated

Evaluation of Raltegravir Plus Maraviroc Therapy in Controlled HIV Patients Presenting With Lipohypertrophy (ROCnRAL)

Human Immunodeficiency Virus | Lipohypertrophy

France
Rodwick, Barry M., M.D.
Abbott

Terminated

Pilot Assessment of Lopinavir/Ritonavir and Maraviroc (PALM)

HIV Infections | Acquired Immunodeficiency Syndrome

United States
Apogenix GmbH

Completed

APG101 in Glioblastoma

Glioblastoma Multiforme

Austria, Germany
Hospital Clinic of Barcelona

Completed

Study Comparing Two Alternatives of Antiretroviral Therapy as Post-exposure Prophylaxis to HIV-1:FOVIR+EMTRICITABINA + LOPINAVIR/RITONAVIR VS TENOFOVIR+EMTRICITABINA + MARAVIROC (MARAVI-PEP)

HIV Infection

Spain
Rockefeller University
Merck Sharp & Dohme LLC; Pfizer; Aaron Diamond AIDS Research Center

Completed

Standard Antiretroviral v. Multi-class Therapy in Acutely HIV-1 Infected Antiretroviral-Naïve Subjects (ADARC 2007-01)

HIV Infections

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

First Study to Evaluate the Capacity of Maraviroc Drug to Protect Against HIV Infection in Samples of Rectal Mucosa From Healthy Volunteers

HIV

Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Neuroblastoma

United States, Canada
European Organisation for Research and Treatment...

Unknown

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With Surgery

Melanoma (Skin)

France, Spain, Belgium, Germany, Italy, United Kingdom, Netherlands
Hoffmann-La Roche

Completed

INNOVE Study: A Study of 3 Months Induction With Fuzeon (Enfuvirtide) + Optimized Background (OB) Versus OB Alone in HIV-1 Infected Patients With Virological Failure.

HIV Infections

France
St. Hope Foundation
GlaxoSmithKline

Completed

Switching Undetectables to Selzentry (SUDS)

Human Immunodeficiency Virus | AIDS

United States
INSYS Therapeutics Inc

Completed

Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States
National Center for Global Health and Medicine,...

Completed

Safety Study of Maraviroc's Effect on Human Osteoclasts (MVC-Bone)

HIV Infections | AIDS

Japan
Robert L. Murphy
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir (EraMune02)

HIV Infection

United States
Northwestern University
Pfizer; Tibotec, Inc

Completed

Maraviroc Plus Darunavir/Ritonavir for Treatment-Naïve Patients Infected With R5-tropic HIV-1 (MIDAS)

HIV Infections | HIV-1 Infection

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Neuroblastoma | Melanoma (Skin)

United States, Canada, Australia
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI); Pfizer

Completed

Effect of Maraviroc on Endothelial Function in HIV-Infected Patients

HIV Infections | HIV Infection | Inflammation | Cardiovascular Disease

United States
Boehringer Ingelheim

Terminated

SPRING: Safety, Efficacy, Pharmacokinetics of tipRanavir/r IN Race/Gender HIV+ Patients Randomized to TDM or SoC

HIV Infections

United States, Argentina, Brazil, Canada, Germany, Italy, Spain
Zimmer Biomet

Terminated

Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws

Degenerative Disc Disease | Spinal Stenosis | Spondylolisthesis

United States
National University Hospital, Singapore
Merck Sharp & Dohme LLC

Unknown

An Observational Study of Ertapenem in Outpatient Parenteral Antibiotic Therapy (OPAT) for Complicated Urinary Tract Infections.

Urinary Tract Infections

Singapore
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Pfizer; Gilead Sciences; Janssen-Cilag Ltd.

Completed

Optimisation of Primary HIV1 Infection Treatment(ANRS 147 OPTIPRIM)

HIV-1 Infections

France
NuVasive

Completed

Osteocel® Plus in Anterior Cervical Discectomy and Fusion (ACDF)

Degenerative Disc Disease in Cervical Spine

United States

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