Search clinical trials for: Multicenter Randomized Study

Total 127379 results

AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Elective Unilateral Total Knee Replacement (ARX-F01)

Post Operative Pain

United States
Takeda

Completed

A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis

Erosive Esophagitis

Japan
UltraShape
Syneron Medical

Completed

A Multicenter,2-Arm,Randomized,Controlled Study Evaluate the Effectiveness of the UltraShape® Contour I VER 3.1 System for Non-Invasive Reduction in Abdominal Circumference

Body Sculpting

United States, Israel
Jaap Bonjer

Unknown

COLOR II: Laparoscopic Versus Open Rectal Cancer Removal (COLORII)

Rectal Cancer

Netherlands, Sweden, Spain, Korea, Republic of, Belgium, Canada, Denmark, Germany, Poland
Kumamoto University

Completed

Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese Patients

Myocardial Infarction

Japan
China Academy of Chinese Medical Sciences
Chengdu University of Traditional Chinese Medicine; Beijing Children's Hospital and other collaborators

Completed

Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study

Hand, Foot and Mouth Disease

China
National Taiwan University Hospital

Available

A Multicenter Randomized Parallel-group Study to Investigate the Efficacy of a Combination of Rosuvastatin and Fenofibrate in the Patients With Diabetes or Atherosclerotic Vascular Diseases With Metabolic Syndrome

Diabetes | CVD
Ullevaal University Hospital
University of Tromso; Helse Stavanger HF; Haukeland University Hospital; St. Olavs... and other collaborators

Completed

Disc Prosthesis Versus Multidisciplinary Rehabilitation

Degenerative Disc Disease | Chronic Low Back Pain

Norway
Eurofarma Laboratorios S.A.

Completed

A Non-inferiority, Multicenter and Randomized, Multiple-Dose Study About a Treatment to Hypolactasia (LAILAII)

Lactose Intolerance

Brazil
Eurofarma Laboratorios S.A.

Completed

A Non-inferiority, Multicenter and Randomized, Single-Dose Study About a Treatment to Hypolactasia (LAILAI) (EF099)

Hypolactasia

Brazil
Centre Hospitalier d'Agen

Unknown

Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in out-of Hospital Setting During Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients. VeNIS BPCO (VeNIS BPCO)

Acute Respiratory Failure | Exacerbation of COPD | Non Invasive Positive Pressure Ventilation | Out of Hospital Setting
QLT Inc.

Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Paclitaxel/Carboplatin as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Stage IV Non-small Cell Lung Cancer | Stage IIIb Non-small Cell Lung Cancer
QLT Inc.

Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Vinorelbine as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Stage IV Non-small Cell Lung Cancer | Stage IIIb Non-small Cell Lung Cancer
The Second People's Hospital of Sichuan
Biotech Pharmaceutical Co., Ltd.

Unknown

Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx Cancer

Hypopharyngeal Cancer | Oropharyngeal Cancer

China
Pfizer

Terminated

Open Label, Multicenter, Randomized, Controlled Study of IM or Oral Exemestane (Aromasin) in Postmenopausal Women

Breast Neoplasms

United Kingdom
University of California, Irvine

Completed

A Randomized Multicenter Clinical Study On the High Vacuum Body Cavity Drainage System Following Open Heart Surgery (NO-NUMO)

Coronary Artery Disease | Heart Valve Disease

United States
Ophthalmic Consultants of Long Island
Bausch & Lomb Incorporated

Completed

Multicenter, Randomized, Controlled Study of the Effect of Lotemax on Initiation of Dry Eye Treatment With Restasis

Keratoconjunctivitis Sicca | Dry Eye Disease

United States
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Oral Lixivaptan Capsules in Subject With Euvolemic Hyponatremia

Hyponatremia With Normal Extracellular Fluid Volume

United States, Canada, Germany, India, Poland, Belgium
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of Oral Lixivaptan Capsules in Subjects With Euvolemic Hyponatremia

Euvolemic Hyponatremia

United States, Israel, India, Mexico, Peru, Belgium, Czech Republic, Italy
Hospital Authority, Hong Kong
Novartis

Terminated

A Randomized, Double-blind, Placebo-controlled Multicenter Study to Assess the Efficacy, Safety and Tolerability of Tegaserod 2 mg Bid vs Placebo in Patients With Chronic Constipation

Constipation | Chronic Disease

China
Ferring Pharmaceuticals

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH

InFertility

United States
Xian-Janssen Pharmaceutical Ltd.

Completed

A Randomized, Double-blind, Flexible Dose, Multicenter Study to Evaluate the Effectiveness and Safety of Galantamine IR in Mild to Moderate Alzheimer's Disease

Alzheimer Disease
Pfizer

Completed

A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children

Tonsillitis

Canada, United States, Costa Rica, Guatemala, India
QLT Inc.

Terminated

A Phase II, Randomized, Cross-Over, Vehicle-Controlled, Double-Blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis

End Stage Renal Disease

United States
Peking University People's Hospital

Completed

Bevacizumab for Neovascular Age-related Macular Degeneration

Exudative Age-related Macular Degeneration

China
Radboud University Medical Center
Karolinska Institutet; Maastricht University Medical Center; Amsterdam UMC, location... and other collaborators

Completed

Comparison of Effectiveness and Costs of Post-diagnosis Treatment in Dementia (AD-Euro)

Dementia

Netherlands
Shanghai Mental Health Center
Shanghai Hotmed Sciences Co.,LTD

Completed

A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of Schizophrenia

Agitation

China
CardioKine Inc.
Biogen; Cardiokine Biopharma, LLC

Withdrawn

International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia

Hypervolemic Hyponatremia
AstraZeneca

Terminated

GALLEX 6: Study to Evaluate the Safety and Tolerability of Tesaglitazar in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States, Brazil, United Kingdom, Finland, Argentina, Canada, Mexico
Bispebjerg Hospital

Completed

A Randomized Multicenter Study of Daylight Mediated Photodynamic Therapy (PDT)

Actinic Keratoses

Denmark
University Hospital, Bordeaux
Ministry of Health, France

Completed

Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care) (IVOIRE)

Shock, Septic | Renal Failure, Acute

France, Belgium, Netherlands
Shanghai Mental Health Center

Completed

A Study to Evaluate the Efficacy and Safety of Seroquel in Chinese Han Patients With Schizophrenia

Schizophrenia

China
International Biomedical Systems S.p.A.

Unknown

European Multicenter, Randomized, Comparative Efficacy/Safety Study of the Mar-Tyn TiN-Coated Stent (MARTIN)

Coronary Artery Disease | Angioplasty, Transluminal, Percutaneous Coronary | Stents

Germany, Italy, Netherlands, Switzerland
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Legtest Multi Centre Testing of the Lively Legs Program for Promoting Compliance in Leg Ulcer Patients

Leg Ulcers | Varicose Ulcers

Netherlands
Schering-Plough

Completed

A Multicenter, Randomized, Controlled Trial of SCH 619734 for the Treatment of Chemotherapy-Induced Nausea and Vomiting (Study P04351AM2)(COMPLETED)

Nausea | Vomiting
Laboratorios Osorio de Moraes Ltda.

Unknown

Phase III Open Study, Prospective, Multicenter, Randomized, Comparative to the Positive Control for Evaluating the Efficacy and Safety of Auris-Sedina in the Symptomatic Control of Otalgy in Patients With or Without Acute External Otitis. (E02OSMAS0108)

Otitis | Efficacy | Tolerability

Brazil
Facet Biotech
PDL BioPharma, Inc.

Withdrawn

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis

Intravenous Steroid-Refractory Ulcerative Colitis
Ever Neuro Pharma GmbH
acromion GmbH

Completed

Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease (Combi)

Alzheimer Disease

Spain
Sanofi

Completed

Randomized Multicenter Study Comparing Docetaxel Plus Cisplatin and 5-FU to Cisplatin Plus 5-FU in Advanced Gastric Cancer

Stomach Neoplasm
AstraZeneca

Completed

A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis

Erosive Esophagitis
AstraZeneca

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)
AstraZeneca

Completed

A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)
Assistance Publique - Hôpitaux de Paris
Chiron Corporation

Unknown

Treating Patients With Childhood Acute Myeloid Leukemia With Interleukin-2 (Elam02)

Leukemia

France
Sun Yat-sen University

Completed

Prospective, Randomized, Multicenter, Control Study to Assess the Efficacy and Safety of Tacrolimus in Induction and Maintenance Phase Treatment in Lupus Nephritis

Kidney Diseases | Lupus Nephritis | Tacrolimus | Induction Phase | Maintenance Phase

China
Pfizer

Completed

Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain

Low Back Pain

Chile, Venezuela, Ecuador, Colombia, Brazil, Mexico, Argentina, Peru, Costa Rica
Pfizer

Completed

An Open, Prospective, Randomized, Multicenter Study of the Efficacy and Safety of Intravenous Followed by Oral Azithromycin Versus Cefuroxime Alone or With Oral Erythromycin for the Treatment of Chinese Patients Who Were Hospitalized for Pneumonia

Pneumonia

China
Aesculap AG

Completed

Clinical Use of an Absorbable Coated Suture Material in Surgery (Safil)

Gastrointestinal Diseases | Laparotomy | Anastomosis, Surgical | Absorbable, Coated Sutures

Hungary
AstraZeneca

Terminated

GALLEX 4 - Long-Term Extension Study to Evaluate Tesaglitazar Therapy in Patients With Type 2 Diabetes

Type 2 Diabetes

Italy, Poland, South Africa, Malaysia, Hungary, Belgium, Slovakia, Philippines, Thailand, Hong Kong
Rabin Medical Center

Unknown

The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study

Lung Transplantation | Primary Graft Dysfunction

Israel
AGO Study Group

Completed

Randomized, Multicenter, 2-Dose Level. Open-Label, Phase IIa Study With the Intraperitoneally Infused Trifunctional Bispecific Antibody Removab(TM) (Anti-EpCAM x Anti-CD3) to Select the Better Dose Level in Platinum Refractory Epithelial Ovarian Cancer Patients

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Cancer

Germany

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