Search clinical trials for: Nicotinic agonist

Total 14677 results

Ochsner Health System

Withdrawn

Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)

Postoperative Nausea and Vomiting

United States
Centre for Addiction and Mental Health
Pfizer; Brainsway

Completed

Deep rTMS and Varenicline for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder

Canada
University of Kansas Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Individualizing Pharmacotherapy for African American Smokers

Smoking Cessation

United States
Ottawa Hospital Research Institute

Completed

The PROMPT Pilot Study

Tobacco Use Disorder | Tobacco Use Cessation | Tobacco Dependence
Georgia State University

Completed

Messages About Reduced Nicotine in Combusted Tobacco Products

Smoking | Risk Behavior | Smoking, Tobacco | Smoking Behaviors | Health Communication

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Nasopharyngeal Carcinoma | Current Smoker | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Al-Azhar University

Completed

Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS

Analgesia | Functional Endoscopic Sinus Surgery | Premedication

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Smartphone-Delivered Attentional Bias Modification Training in Helping Patients Quit Smoking

Current Every Day Smoker

United States
Rose Research Center, LLC
Foundation for a Smoke-Free World

Completed

Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment (HAVE)

Smoking Cessation | Nausea | Stress | Sleep Disturbance

United States
Brown University
Truth Initiative

Completed

Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial

Smoking Cessation

United States
Yale University

Completed

Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans

Cocaine Dependence

United States
Mayo Clinic

Withdrawn

Feasibility of Treatment for Vaping Cessation (VAPEscape)

Vaping

United States
Duke University
National Institute on Drug Abuse (NIDA)

Completed

The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products (ENDS-Switch)

Nicotine Dependence, Cigarettes

United States
Brown University

Active, not recruiting

Using ANDS to Reduce Harm for Low SES Cigarette Smokers

Nicotine Dependence | Smoking, Cigarette

United States
University of Wisconsin, Madison
Washington University School of Medicine; National Heart, Lung, and Blood Institute...

Completed

UW Quitting Using Intensive Treatment Study (QUITS) (QUITS)

Tobacco Dependence

United States
Kaiser Permanente
National Cancer Institute (NCI)

Completed

Development of a mHealth Intervention for Ambivalent Smokers

Smoking Cessation | Tobacco Use Disorder | Motivation | Behavior, Smoking

United States
University of Minnesota
University of Pennsylvania; Brown University; Duke University; University of California... and other collaborators

Completed

Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace

Tobacco Smoking | Nicotine Dependence

United States
Centre for Addiction and Mental Health

Completed

Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada

Tobacco Use Cessation

Canada
Rush University Medical Center

Completed

Varenicline for Gait and Balance Impairment in Parkinson Disease (Chantix-PD)

Parkinson Disease

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

The Effect of Electronic Cigarette Liquid Characteristics in Smokers.

Electronic Cigarettes

United States
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Efficacy of the Use of Genetic Markers in the Choice of the Pharmacological Treatment of Smoking (GENTSMOKING) (GENTSMOKING)

Smoking Cessation | Genetic Predisposition

Brazil
University of Virginia

Completed

QuitAid Pilot Feasibility Trial

Smoking Cessation

United States
Brown University
National Institute on Drug Abuse (NIDA); University of Vermont

Completed

Project 3, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in People With Current Affective Disorders

Tobacco Use Disorder

United States
University of Vermont
National Institute on Drug Abuse (NIDA)

Completed

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

Nicotine Dependence, Cigarettes

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University

Completed

Project 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid Abusers (P2S2)

Tobacco Use Disorder

United States
University of Kansas Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Changing the Default for Tobacco Treatment

Tobacco Use Cessation

United States
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University

Completed

Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women

Tobacco Use Disorder

United States
Virginia Polytechnic Institute and State University

Completed

Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace

Tobacco Use

United States
Merck Sharp & Dohme LLC

Completed

Evoked Responses as Pharmacodynamic Biomarkers in Healthy and Schizophrenic Participants (MK-4334-007)

Cognitive Impairment Associated With Schizophrenia

United States
H. Lee Moffitt Cancer Center and Research Institute
James and Esther King Biomedical Research Program

Completed

Facilitating Smoking Cessation With Reduced Nicotine Cigarettes

Smoking Cessation

United States
Center for Ophthalmic and Vision Research, LLC

Completed

OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers

Dry Eye

United States
University of Zagreb
Harvard Medical School (HMS and HSDM); University of Ljubljana School of Medicine... and other collaborators

Completed

Varenicline Versus Cytisine for Smoking Cessation in Primary Care Setting

Smoking Cessation

Croatia, Slovenia
Brown University
National Cancer Institute (NCI)

Completed

Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers

Nicotine Dependence

United States
Rhode Island College
National Institute on Drug Abuse (NIDA)

Withdrawn

Comparing Two Treatments That Both Target Smoking Cessation and Weight Loss at the Same Time. (BREATH)

Smoking Cessation | Weight Loss

United States
King's College London
AstraZeneca; Helse Stavanger HF; Michael J. Fox Foundation for Parkinson's Research and other collaborators

Withdrawn

Parkinson's Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug (PD-MIND)

Parkinson Disease | Mild Cognitive Impairment
Axsome Therapeutics, Inc.

Completed

A Trial of AXS-05 in Patients With Major Depressive Disorder (GEMINI)

Depression | Major Depressive Disorder

United States
Axsome Therapeutics, Inc.

Completed

Open-Label Safety Study of AXS-05 in Subjects With Depression

Depression | Major Depressive Disorder | Treatment Resistant Depression

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users

Electronic Cigarettes

United States
University of Vermont

Completed

Switching to Very Low Nicotine Content Cigarettes vs Reducing Cigarettes Per Day

Tobacco Use Disorder

United States
University of Minnesota

Completed

Methods Project 4: Clinical Trial - Amended (COMET)

Tobacco Smoking

United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI); National Institutes of Health (NIH)

Withdrawn

Young Adults and Low Nicotine Cigarettes (YLP)

Smoking

United States
University of California, San Francisco
Tobacco Related Disease Research Program

Completed

Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment

Smoking Cessation | Tobacco Use | Nicotine Dependence | Cigarette Smoking

United States
Rutgers, The State University of New Jersey
National Institute on Drug Abuse (NIDA)

Completed

Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI) (PTSC-S)

Schizophrenia | Schizoaffective Disorder | Tobacco Use | Tobacco Smoking | Tobacco Use Disorder | Tobacco Use Cessation

United States
University of Vermont

Completed

E-cigarette Nicotine Study

Electronic Cigarette Use | Nicotine Dependence | Cigarette Smoking

United States
Medical University of South Carolina

Completed

Translational Neuropsychopharmacology Research of Nicotine Addiction

Nicotine Dependence, Cigarettes

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Pfizer

Terminated

Management of Tobacco Treatment Intervention in Reducing Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes

Lung Carcinoma

United States
Maggie M Sweitzer, PhD
National Institute on Drug Abuse (NIDA)

Completed

Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation

Smoking

United States
RAI Services Company

Completed

CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers

Smoking | Tobacco Use | Tobacco Smoking

United States
RAI Services Company

Completed

CSD201202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System P12

Smoking | Tobacco Use

United States
Oyster Point Pharma, Inc.

Completed

Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)

Dry Eye Disease

Mexico

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