Search clinical trials for: Omeprazole

Total 439 results

University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes

Pharmacokinetics | Cytochrome

Switzerland
Daniel Freedberg

Completed

Effects of Gastric Acid on Colonic Microbiome

Clostridium Difficile

United States
Keio University

Withdrawn

Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer

Peptic Ulcers

Japan
Coordinación de Investigación en Salud, Mexico

Completed

Efficacy on Helicobacter Pylori Eradication With Two Antibiotic Regimens

Helicobacter Infections
LILIA GONZALEZ CERON
Pan American Health Organization; Instituto de Diagnóstico y Referencia Epidemiológicos... and other collaborators

Completed

Effectiveness of Malaria Treatment in Mexico (EMTM)

Malaria
Bayer
Bausch Health Americas, Inc.

Completed

A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (CL2007-17 )(P07813)(COMPLETED)

Gastric Acid | Human Experimentation
Bayer

Completed

Study to Compare Gastric Inhibition of Two Proton Pump Inhibitors (CL2008-18)(P07815)(COMPLETED)

Human Experimentation
Bayer

Completed

Pharmacodynamic Study Comparing the Effects of Two Different Forms of Omeprazole (P07812) (COMPLETED)

Intragastric Acidity
Bayer
Bausch Health Americas, Inc.

Completed

A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (Study CL2008-02)(P07814)(COMPLETED)

Gastric Acid | Human Experimentation
Bayer

Completed

Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)

Heartburn
Boehringer Ingelheim

Withdrawn

Effect of BI 1181181 on Midazolam, Warfarin, Omeprazole and Digoxin

Healthy

Germany
Bayer

Completed

A Study to Compare Omeprazole Administered as Zegerid® Powder and as Prilosec® Capsule in Healthy Participants (P08050)(CL2010-12)

Heartburn
RenJi Hospital

Completed

Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia

Depression | Dyspepsia | Compliance

China
Pronova BioPharma

Completed

PRC-4016 (Icosabutate) Phase I Drug-drug Interaction Study

Healthy

United Kingdom
Seoul National University Hospital

Completed

Influence of CYP2C19 Polymorphism on PK/PD of Omeprazole

Stomach Ulcer

Korea, Republic of
National Cancer Institute (NCI)

Completed

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid Tumors

Adult Solid Neoplasm

United States
Boehringer Ingelheim

Completed

The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)

Healthy

Germany
University of Oklahoma

Completed

Influence of the Proton Pump Inhibitor Omeprazole on the Anti-Platelet of P2Y12 Antagonists in Subjects With Coronary and Peripheral Artery Disease

Coronary Artery Disease | Peripheral Artery Disease

United States
University of Michigan Rogel Cancer Center

Withdrawn

A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer

Cancer of Head and Neck

United States
Boehringer Ingelheim

Completed

Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Study to Determine the Effects of Multiple-dose Omeprazole on the Single-dose Pharmacokinetics of Tipranavir (TPV) Coadministered With Ritonavir (RTV) in Healthy Adult Volunteers

Healthy
Ardelyx
AstraZeneca

Completed

A Phase 1 Study to Examine the Pharmacodynamics of Different AZD1722 Formulations

Healthy

United States
Boehringer Ingelheim

Completed

Effects of Tipranavir (With Ritonavir) Capsule and Liquid Formulation on Cytochrome P450 and P-glycoprotein Activity in Healthy Volunteers

Healthy
Jules Desmeules

Completed

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Healthy Volunteers

Switzerland
Repros Therapeutics Inc.

Completed

Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female Subjects

Drug Interactions

United States
Mayo Clinic

Completed

The Impact of Proton Pump Inhibitors on the Fecal Microbiome

Healthy | Clostridium Difficile Infection

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males

Pharmacokinetics of ASP8477 | Pharmacodynamics of ASP8477

France, Belgium
Effexus Pharmaceutical
Southern Arizona VA Health Care System

Unknown

Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.

Heartburn | Gastroesophageal Reflux Disease (GERD) | Indigestion

United States
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
Bristol-Myers Squibb

Completed

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

Transplant Rejection

United States
Belarusian Medical Academy of Post-Graduate Education
Dr. Reddy's Laboratories Limited

Unknown

Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate Severity

GERD

Belarus
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Drug Interaction Study of JNJ-26489112 in Healthy Volunteers

Healthy

Belgium
Synergy Pharmaceuticals Pte. Ltd.
Singapore General Hospital

Terminated

Safety and Efficacy Study of a Non-antibiotic Treatment for the Eradication of Helicobacter Pylori

Helicobacter Pylori Infection

Singapore
Matthias Schwab

Terminated

Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted Dosing (GERD)

Gastroesophageal Reflux

Germany
Chonbuk National University Hospital

Completed

Clinical Trials on Evaluate the Red Ginseng and Fermented-Red Ginseng Affect to Drug Metabolizing Enzyme and Transporter in Healthy Volunteers

Healthy

Korea, Republic of
Pfizer

Completed

Drug-Drug Interaction Study With PF-05089771

Healthy

Belgium
University of Roma La Sapienza

Unknown

"Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- (dOPPLER)

Coronary Artery Disease

Italy
Boehringer Ingelheim

Completed

Drug-drug Interaction Study of Aggrenox and Omeprazole in Normal Volunteers

Healthy

United States
AstraZeneca

Completed

Prilosec Bioequivalence Study in Healthy Volunteers

Bioequivalence, AUC, Cmax, Pharmacokinetics

United States
Royal Marsden NHS Foundation Trust

Unknown

IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast Cancer

Breast Cancer | Radiation Fibrosis

United Kingdom
Lymphoma Trials Office

Unknown

Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach

Gastric Cancer

United Kingdom, Hong Kong, Switzerland, Poland, South Africa
St Marina University Hospital, Varna, Bulgaria

Completed

Lactobacillus Reuteri ProGastria in Helicobacter Pylori-infected Adult Subjects on Proton Pump Inhibitors

Helicobacter Pylori Infection

Bulgaria
USDA Beltsville Human Nutrition Research Center

Completed

Gastric pH and Anthocyanin Absorption

Anthocyanin Metabolism

United States
Norgine

Completed

Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux Disease

Gastroesophageal Reflux

Poland
Tehran University of Medical Sciences

Completed

The Effect of Helicobacter Pylori Eradication on Liver Fat Content in Non-alcoholic Fatty Liver Disease

Fatty Liver | Insulin Resistance | Liver Dysfunction

Iran, Islamic Republic of
Presidio Pharmaceuticals, Inc.

Completed

A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and Omeprazole

Pharmacokinetic Assessments in Healthy Volunteers

United States
Xijing Hospital

Completed

Effect of Omeprazole on Metformin

Healthy

China
Faculdade de Ciências Médicas da Santa Casa de...

Completed

Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis

Gastroesophageal Reflux Disease (GERD) | Chronic Laryngitis

Brazil
Soroka University Medical Center

Unknown

Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC

CDA Type I
University of Wisconsin, Madison

Completed

Does Omeprazole Decrease Intestinal Calcium Absorption?

Osteoporosis | GERD | Hip Fracture | Achlorhydria

United States

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