Search clinical trials for: Open-label study

Total 119973 results

Peregrine Pharmaceuticals

Terminated

Open-label, Single Arm, Tumor Imaging and Dosimetry Study of I-124 PGN650 in Advanced Solid Tumors

Malignant Solid Tumor

United States
Biointegrator LLC

Completed

Open-label Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Auriхim

Lymphoma, Follicular | Lymphoma, Non-Hodgkin

Russian Federation
Sunovion

Completed

Open-label Safety Study in Adults With ADHD

Adult Attention Deficit Hyperactivity Disorder

United States
KAI Pharmaceuticals

Terminated

Open-label Study to Assess the Long-term Safety and Efficacy of Etelcalcetide (Also Known as AMG 416 or KAI-4169) in Patients With Secondary Hyperparathyroidism

Secondary Hyperparathyroidism
GlaxoSmithKline

Completed

A Clinical Evaluation Of BW430C (Lamotrigine) In Bipolar I Disorder- Long-term Extension Of Study SCA104779 (NCT00550407) -

Bipolar Disorder

Japan
Pearl Therapeutics, Inc.

Completed

Extension Study to Evaluate the Safety and Efficacy of PT003, PT001, and PT005 in Subjects With Moderate to Very Severe COPD, With Spiriva® Handihaler® (PINNACLE 3)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Australia, New Zealand
UNC Lineberger Comprehensive Cancer Center

Completed

Open-label Pilot Evaluating Renal Lesions w/ Contrast-enhaced US in Patients w/ Renal Cancer

Kidney Cancer

United States
Yaffa Golan, Ltd.

Completed

Open-label Pilot Study to Assess the Use of Magic Foot™ in the Improvment of Parameters in Subject With Foot Symptoms (MF)

Diabetes | Peripheral Vascular Disease

Israel
Mara Chambers
Novartis

Completed

Study of Combined Fulvestrant and Everolimus in Advanced/Metastatic Breast Cancer After Aromatase Inhibitor Failure (BRE-43)

Breast Cancer

United States
Tayside Medical Science Centre

Withdrawn

Ethyl Chloride Spray Versus Subcutaneous Lidocaine Anaesthetic Prior to Contraceptive Implant Insertion

Contraception
Novartis Pharmaceuticals

Completed

Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer

Advanced Breast Cancer

United States
Janssen Research & Development, LLC

Completed

Open-label Study of Flexible-dose Paliperidone ER (Extended Release) to Treat Adolescent Schizophrenia.

Psychotic Disorders | Schizophrenia | Schizophrenic Disorders | Dementia Praecox

United States, Belgium, Poland, Bulgaria, India, Romania, Russian Federation, Ukraine, Korea, Republic of, Estonia, Finland
GlaxoSmithKline

Terminated

Open-label Study to Investigate the Safety, Tolerability, PK, and Pharmacodynamics of the AKT Inhibitor GSK690693

Cancer

United States
New York State Psychiatric Institute
Pfizer

Completed

Open-label Ziprasidone Study for Psychosis Treatment in Adolescents

Schizoaffective Disorder | Schizophreniform Disorder | Bipolar Disorder | Depressive Disorder, Major | Psychosis

United States
GE Healthcare
Quintiles, Inc.; H2O Clinical LLC

Completed

Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.

Ventricular Dysfunction, Left | Heart Failure (HF)

United States
Novartis Vaccines

Completed

Open-label, Uncontrolled Postmarketing Study of Cell-derived A/H1N1 Influenza HA Vaccine in Japanese Elderly Subjects

Swine-Origin Influenza A H1N1 Virus

Japan
Novartis

Completed

Open-label Study to Investigate Systemic Exposure in Adult and Pediatric Atopic Dermatitis Patients Treated 8.5 Days With Pimecrolimus Cream 1% Under Occlusion

Atopic Dermatitis

Germany
UCB BIOSCIENCES, Inc.
Parexel

Completed

Open-label, Bioequivalence Study of Certolizumab Pegol 200 mg Solution Injected Either by a Prefilled Syringe (Reference) or by an E-Device (Test) in Healthy Subjects

Healthy

United States
Duramed Research

Completed

Open-label Study to Evaluate the Efficacy and Safety of an Extended-cycle, Low Dose Combination Oral Contraceptive

Contraception

United States
Fundacion Clinic per a la Recerca Biomedica

Completed

Open-label Study in Patients With Metastatic NSLC Treated With Cisplatin, Gemcitabine and Bevacizumab

Non-Small Cell Lung Cancer (NSCLC)

Spain
Boehringer Ingelheim

Completed

J-TARGET,Japanese Telmisartan Study for Antihypertensive Good Effect in Long Term Observation

Hypertension
InnaVirVax

Unknown

Open-label, Phase I/IIa Study of VAC-3S in HIV-1 Patients Who Showed an Immune Response to VAC-3S During IVVAC-3S/P1

HIV

France
Threshold Pharmaceuticals

Unknown

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Puma Biotechnology, Inc.

Completed

Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects

Healthy

United States
SciVision Biotech Inc.

Withdrawn

Safety and Efficacy Study of Lidocaine Mixed Hyaluronate on Nasolabial Folds Correction

Pain | Nasolabial Folds Correction

Taiwan
Ablynx

Completed

Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Russian Federation, Canada, Hungary, Japan, Serbia, South Africa, Switzerland
Amgen

Completed

AMG 172 First in Human Study in Patients With Kidney Cancer

Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Clear Cell Renal Carcinoma | Renal Cell Adenocarcinoma

France, United States, Germany
Maruho Co., Ltd.

Completed

Open-label Study of ASP2151 in Herpes Simplex Patients

Herpes Simplex

Japan
BioCryst Pharmaceuticals

Terminated

Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema (OPuS-4)

Hereditary Angioedema | HAE

France, Belgium
Horizon Pharma Ireland, Ltd., Dublin Ireland
Pediatric Rheumatology Collaborative Study Group

Completed

Open-label Safety and Pharmacokinetic Study of DUEXIS® (Ibuprofen and Famotidine) Tablets in Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States
Memorial Sloan Kettering Cancer Center
Synta Pharmaceuticals Corp.

Completed

Open-label Study of STA-9090 for Patients With Metastatic Breast Cancer

Breast Cancer

United States
National Taiwan University Hospital

Unknown

A Study Comparing the Supraglottic Airway Devices and Endotracheal Tube During Controlled Ventilation for Laparoscopic Surgery

The Comparison of the I-gel and Endotracheal Tube About in Different Ventilation Settings During Laparoscopic Surgery

Taiwan
Amgen

Completed

Open-label Study Using 50 Mg Liquid Etanercept Subcutaneous Injection in the Thigh to Compare an Auto-injector Device and a Manual Injection in Healthy Subjects

Healthy Men and Women
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of a Single Dose of Digoxin on the Actions in the Bodies of Healthy Subjects After Having Taken Several Doses of YM178

Healthy

France
Assistance Publique Hopitaux De Marseille

Unknown

Efficacy of Lidocaine Versus Placebo in Palliative Care Patients With Opioid-refractory Cancer Pain With Neuropathic Component: a Multicenter, Prospective, Double-blind Randomized Placebo-controlled Study. (LIDOSP)

Cancer | Pain With Neuropathic Component

France
UCB Pharma SA

Completed

Open-label Study of Levetiracetam Intravenous Infusion in Children (1 Month-4 Years Old) With Epilepsy

Epilepsy

France, United States, Mexico, Turkey, Belgium, Germany
Northwell Health

Terminated

An Exploratory, Randomized, Blinded, Placebo-Controlled Trial of Folic Acid and L-methylfolate in Parkinson's Disease

Parkinson's Disease

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole (ARRIVE US)

Schizophrenia

United States, Canada
Thomas Jefferson University

Terminated

Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks

Migraine

United States
Actelion

Completed

Open-label Study With Bosentan in Interstitial Lung Disease (BUILD 2 OL)

Interstitial Lung Disease | Scleroderma

United States, Korea, Republic of, Israel, France, United Kingdom, Netherlands, Switzerland, Germany, Canada, Italy, Sweden
Roswell Park Cancer Institute

Terminated

Fulvestrant in Treating Patients With Recurrent Prostate Cancer

Prostate Cancer

United States
Novartis

Withdrawn

Open-label Study, to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Bone Lesions Secondary to Multiple Myeloma.

Multiple Myeloma
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S; Otsuka America Pharmaceutical

Completed

Open-label, Extension Study of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in Patients With Schizophrenia

Schizophrenia

United States, Croatia, Latvia
Regeneron Pharmaceuticals
Bayer

Completed

Open-label Extension Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Neovascular ("Wet") Age-related Macular Degeneration (AMD)

Neovascular Age-related Macular Degeneration

United States, Canada
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole (ARRIVE- EU)

Schizophrenia

Belgium, Bulgaria, Canada
Upsher-Smith Laboratories

Completed

Open-label Extension Study to Evaluate the Safety of USL255 in Patients With Refractory Partial-onset Seizures

Epilepsy

Australia, Canada, Poland, United States, Belgium, Spain, Argentina, Israel, India, South Africa, Greece, Russian Federation, Chile, New Zealand, Germany
XOMA (US) LLC

Completed

Open-label Safety Extension Study of Gevokizumab in Erosive Osteoarthritis of the Hand

Osteoarthritis

United States
Valneva Austria GmbH

Completed

Open-label, Randomized Study in a Pediatric Population in a JEV (Japanese Encephalitis Virus)-Endemic Country

Japanese Encephalitis

Philippines
Bial - Portela C S.A.

Completed

Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Phenytoin.

Epilepsy
Trevena Inc.

Completed

A Safety, Tolerability, PD and PK Study in Healthy Adults

Healthy

United States

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