Search clinical trials for: PPI

Total 403 results

Ocera Therapeutics

Terminated

Safety and Efficacy of AST-120 in Patients With GERD Who Continue to be Symptomatic on a Standard Dose of PPI

Gastroesophageal Reflux Disease (GERD)

United States
Samsung Medical Center

Unknown

The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD

Gastroesophageal Reflux Disease

Korea, Republic of
AstraZeneca

Completed

Assessment of Low-dose ASA Discontinuation Risk Associated With Concomitant PPI Use During the First Year of ASA Therapy

Cardiovascular Prevention

Spain
Soonchunhyang University Hospital

Completed

Surgicel® Fibrillar for Delayed Bleeding After ESD

Malignant Neoplasm of Stomach | Benign Neoplasm of Stomach

Korea, Republic of
Janssen Korea, Ltd., Korea

Completed

Practice and Patient Compliance on the PPI (Proton Pump Inhibitors) Treatment of Gastroesophageal Reflux in South Korea

Gastroesophageal Reflux
Takeda

Completed

A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis

Erosive Esophagitis

Japan
Federico II University
University of Catanzaro; Ospedale Nuovo Regina Margherita di Roma Dr. Salvatore...

Completed

Proton Pump Inhibitors and Gastrointestinal Symptoms

Gastrointestinal Symptoms | Small Intestinal Overgrowth

Italy
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Birte Glenthoj
University of Copenhagen; Lundbeck Foundation; Glostrup University Hospital,...

Completed

Will Decreased Noradrenergic Activity Normalize Information Processing in Patients With Schizophrenia?

Schizophrenia

Denmark
National Taiwan University Hospital

Completed

A Comparative Study of Proton-pump Inhibitor Tests for Chinese Reflux Patients in Relation to the CYP2C19 Genotypes

GERD
Emory University
AstraZeneca; Respiratory Technology Corporation

Completed

Study of an Oropharyngeal Aerosolized pH Probe for Diagnosing Laryngopharyngeal Reflux (LPR)

Laryngopharyngeal Reflux

United States
Mike O'Callaghan Military Hospital

Withdrawn

The Influence of Proton Pump Inhibitors (PPI's) on Blood Levels of 25-Hydroxyvitamin D.

Vitamin D

United States
Assistance Publique - Hôpitaux de Paris

Completed

Molecular Detection of Antibiotic Resistance and H Pylori Eradication (HELICOSTIC)

Helicobacter Pylori Infection

France
Medical University of Warsaw

Unknown

LGG for Prevention of Infectious Complications During PPI Treatment in Children

Respiratory Tract Infections | Gastroesophageal Reflux Disease | Gastrointestinal Infections

Poland
AstraZeneca

Completed

Recurrence Rate, Risk Factors for the Recurrence, and Quality of Life in Patients With GERD in Korea-an Observational (Refresh)

The Aim of This Study is to Investigate the Frequency and Related Risk Factors of Recurrence, and Quality of Life in Patients With GERD After Treatment With PPI

Korea, Republic of
USDA Beltsville Human Nutrition Research Center

Completed

Gastric pH and Anthocyanin Absorption

Anthocyanin Metabolism

United States
The Catholic University of Korea

Unknown

Sublingual Administration of PPI

Gastric or Duodenal Ulcer

Korea, Republic of
Seoul National University Bundang Hospital

Completed

Eradication Rates of Helicobacter Pylori and Its Affecting Factors

Helicobacter Infections

Korea, Republic of
Society for Applied Studies
Norwegian Institute of Public Health; Christian Medical College, Vellore, India

Completed

Predictors of Poor Immune Response to Rotavirus Vaccine in Infants (PPIR)

Innate Immune Response

India
Thomas Jefferson University

Completed

The Effects of Nexium on the Side Effects Associated With a Colonoscopy Prep

Nausea | Vomiting | Abdominal Pain

United States
Johnson & Johnson Pharmaceutical Research & Development...
Eisai Inc.

Completed

Safety and Efficacy of Rabeprazole in Infants With Gastroesophageal Erosive Reflux Disease (GERD)

Gastroesophageal Reflux

United States, Belgium, Israel, Poland, Australia, Netherlands, South Africa, Hungary, Bulgaria, Denmark
Presidio Pharmaceuticals, Inc.

Completed

A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and Omeprazole

Pharmacokinetic Assessments in Healthy Volunteers

United States
Xijing Hospital

Completed

Effect of Omeprazole on Metformin

Healthy

China
Dexa Medica Group

Completed

Efficacy and Safety of DLBS2411 in Healthy Volunteers

Gastric pH Regulation in Healthy Volunteers

Indonesia
Forest Laboratories

Withdrawn

Safety and Efficacy Study of Ceftaroline in Elderly Subjects With Community-Acquired Bacterial Pneumonia

Community-Acquired Bacterial Pneumonia (CABP)
University of Utah

Terminated

Proton Pump Inhibitor Therapy and Bone Density in Premature Infants (PPI)

Osteopenia | Prematurity

United States
University of Florida
Takeda

Terminated

COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI (GERD/COPD)

Chronic Obstructive Pulmonary Disease | Gastroesophageal Reflux

United States
Duke University
Wallace H. Coulter Foundation

Completed

The Effects of Antihistamines on Pre-Pulse Inhibition (PPI)

Healthy

United States
Infante, Javier Molina, M.D.

Unknown

14-day Quadruple Hybrid vs. Concomitant Therapies for Helicobacter Pylori Eradication

Helicobacter Pylori Infection

Spain, Italy
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1 Study of PPI-668 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) Genotype 1

Hepatitis C, Chronic

United States, Australia, New Zealand
AstraZeneca

Completed

Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Heart Disease Death

Nonfatal Myocardial Infarction | Coronary Death

Spain, Sweden
AstraZeneca

Completed

Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death

Nonfatal Myocardial Infarction | Coronary Death

Spain
Bristol-Myers Squibb

Terminated

Belatacept in Liver Transplant Recipients

Immunosuppression in Solid Organ Transplant

France, Germany, Italy, United States, Austria, Canada, Spain, Argentina, Brazil
AstraZeneca

Completed

A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI) (NEON)

Gastroesophageal Reflux Disease

Chile, Argentina, Venezuela, Colombia
University of Zurich
H. Lundbeck A/S; Psychiatric University Hospital, Zurich

Completed

The Effect of Sertindole on Sensory Gating and Cognition in Healthy Volunteers

Healthy

Switzerland
University of Zurich
H. Lundbeck A/S; University Hospital of Psychiatry, Department Neuropsychopharmacology...

Terminated

The Effect of Sertindole on Sensory Gating and Cognition in Schizophrenic Patients

Schizophrenia

Switzerland
Servicio Canario de Salud
Fundación Canaria de Investigación y Salud

Withdrawn

Strategies for Improving Proton Pump Inhibitors (PPIs) Prescription Associated to Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Adverse Events

Spain
Radboud University Medical Center

Withdrawn

Overactive Bladder (OAB) Drink Advice Study

Overactive Bladder Syndrome

Netherlands
Addex Pharma S.A.

Completed

ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD)

Gastroesophageal Reflux

United States, France, Germany, Netherlands, Switzerland
Columbia University

Terminated

Fundic Gland Polyps and Proton Pump Inhibitor (PPI) Drugs

Fundic Gland Polyps

United States
National Taiwan University Hospital

Unknown

Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasis

Peptic Ulcers

Taiwan
AstraZeneca

Completed

Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder (EVIDENCE)

Osteoarthritis | Rheumatoid Arthritis | Ankylosing Spondylitis

Germany, Sweden, France, Turkey, United Kingdom, Norway, Netherlands, Spain, Greece, Belgium, Switzerland, Italy
AstraZeneca

Completed

Assessment of NSAID-treated Patients Adherence to Co-prescribed Proton Pump Inhibitor (PPI) (CONVOY)

Osteoarthritis | Rheumatoid Arthritis | Ankylosing Spondylitis

Sweden
Nycomed

Completed

Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD) (PANTHER)

Gastroesophageal Reflux Disease

Germany
Nycomed

Completed

Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders (PANDA)

Gastroesophageal Reflux Disease | Sleep Disorders | Non-Erosive Reflux Disease

Germany
Nycomed

Completed

Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease (PARADE)

Gastroesophageal Reflux Disease

Germany
Massachusetts Eye and Ear Infirmary

Withdrawn

Longitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal Reflux

Cough | Gastroesophageal Reflux
Mayo Clinic

Withdrawn

Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis

Gastroesophageal Reflux Disease | Dysphagia | Eosinophilic Esophagitis
University of Florida
Bristol-Myers Squibb; Sanofi

Completed

PPI and Clopidogrel Response

Drug Interaction

United States
Takeda

Completed

A Study of the Effects of Multiple Doses of Dexlansoprazole, Lansoprazole, Omeprazole or Esomeprazole on the Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Participants.

Healthy

United States

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