Search clinical trials for: SMN protein depletion

Total 22474 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
Istituto Auxologico Italiano

Recruiting

Advances in Telephone-based Cognitive Screening Procedures (TBCS)

Cerebrovascular Disorders | Amyotrophic Lateral Sclerosis | Frontotemporal Degeneration | Alzheimer's Disease | Lewy Body Dementia

Italy
Clinical Research Centre, Malaysia

Not yet recruiting

Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia (EVOS)

Staphylococcus Aureus Bacteremia

Malaysia
National University Hospital, Singapore

Recruiting

Ma-Spore ALL 2020 Study

B Lymphoblastic Leukemia

Malaysia, Singapore
Beijing Anzhen Hospital

Recruiting

PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study (PLACARD)

Cardiovascular Disease | Type 2 Diabetes Mellitus

China
Sun Yat-sen University

Recruiting

HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma

Hepatocellular Carcinoma | PD-1 Inhibitor | Lenvatinib | Hepatic Arterial Infusion Chemotherapy

China
CARsgen Therapeutics Co., Ltd.

Not yet recruiting

Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL

Multiple Myeloma | Primary Plasma Cell Leukemia
National Institute of Allergy and Infectious Diseases...

Recruiting

Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.

HIV

United States
AbbVie

Not yet recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Inhye Ahn
Loxo Oncology, Inc.

Recruiting

Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
AbbVie

Recruiting

A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body)

Moderate Plaque Psoriasis

United States, Puerto Rico, Canada, Australia
Women and Infants Hospital of Rhode Island

Not yet recruiting

Intravesical Gentamicin to Prevent Recurrent UTI

Recurrent Uti
The Third Affiliated hospital of Zhejiang Chinese...
Zhejiang University

Recruiting

Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma

Glioma

China
St. Joseph's Hospital and Medical Center, Phoenix

Recruiting

Gentamicin Bladder Instillation on CAUTI

Catheter Infection

United States
Huashan Hospital

Not yet recruiting

Effect of Ketosteril on Sarcopenia in Patients With Chronic Kidney Disease

Chronic Kidney Disease | Sarcopenia

China
Zhejiang University
Shulan (Hangzhou) Hospital

Not yet recruiting

Assessment of AFP and PIVKA-II as Prognostic Indicators in Liver Transplantation for Hepatocellular Carcinoma

Liver Transplantation | Hepatocellular Carcinoma | Alpha-Fetoprotein | Protein Induced by Vitamin K Absence or Antagonist-II
Fujian Cancer Hospital

Not yet recruiting

Stop and go Strategy as First-line Treatment for Widely Metastatic Nasopharyngeal Carcinoma

Metastatic Nasopharyngeal Carcinoma | Intermittent Systematic Chemotherapy
Megalabs

Not yet recruiting

Bioequivalence Study of Palbociclib 125 mg Capsules of Iclos vs. Ibrance (Palbociclib) Capsules 125 mg

Bioequivalence
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Siriraj Hospital

Not yet recruiting

Disease Characteristics and Treatment Response in Plasma Cell Disorders Patients Based on Genetic Abnormalities From Fluorescence In Situ Hybridization and Next Generation Sequencing (genetics MM)

Plasma Cell Disorder
National Yang Ming University

Recruiting

Effects of SugarCut® Unripe Guava Fruit Extract on Blood Glucose Regulation

PreDiabetes

Taiwan
Medical University of Warsaw

Not yet recruiting

Efficacy of Cashew Nut Protein Immunotherapy

Food Allergy

Poland
Hospital Universitario 12 de Octubre

Recruiting

New Protein Biomarkers and Technology for Improving Diagnosis and Outcome Prediction in Mild TBI

Mild Traumatic Brain Injury

Spain
Emory University
National Cancer Institute (NCI); National Center for Complementary and Integrative...

Recruiting

Chaplain-Delivered Compassion Meditation to Improve Spiritual Care of Patients Receiving Stem Cell Transplantation

Lymphoma | Multiple Myeloma

United States
Chang Gung Memorial Hospital
Ministry of Health and Welfare, Taiwan

Recruiting

Innovative Diagnosis and Therapy in LDLT Patients With High-risk Hepatocellular Carcinoma

High Risk of Recurrence

Taiwan
Centre Hospitalier Universitaire de Nice

Recruiting

Vitiligo Treatment by Targeting TYK2 Mediated Responses (ViTYK)

Vitiligo, Generalized

France
Henan Institute of Cardiovascular Epidemiology

Not yet recruiting

SPECT Fibroblast Activation Protein Imaging in Patients With Cardiac Disease

Myocardial Fibrosis
European Organisation for Research and Treatment...
Novartis

Not yet recruiting

177Lu-DOTATATE for Recurrent Meningioma (LUMEN-1)

Recurrent Meningioma
Istituto Auxologico Italiano

Recruiting

Perception of Unpleasant Sensations During Study Procedures in ALS Patients (PESALS)

Amyotrophic Lateral Sclerosis

Italy
National Cancer Institute (NCI)

Not yet recruiting

Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent Glioblastoma
Centre Hospitalier Universitaire de Nice

Recruiting

Ro60 Expression in Macrophages in Sjogren's Disease (RoMioSS)

Sjogren's Syndrome

France
Jinling Hospital, China

Recruiting

Study on the Efficacy and Safety of Low-dose CTX as Maintenance Therapy for MM Unsuitable for Transplantation

Newly Diagnosed Multiple Myeloma

China
The Christie NHS Foundation Trust
CellCentric Ltd.

Not yet recruiting

PatIent exPeRiences and prEFerence of trEatment foR Multiple Myeloma (iPREFER)

Multiple Myeloma

United Kingdom
Fudan University

Not yet recruiting

Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)

Lung Cancer | Minimal Residual Disease | EGFR Gene Mutation
Leuko Labs, Inc.

Not yet recruiting

Pivotal Study to Validate a Novel System to Non-Invasively Detect Severe Neutropenia (PC002)

Multiple Myeloma | Diffuse Large B Cell Lymphoma
Walton Centre NHS Foundation Trust
University of Liverpool; National Institute for Health Research, United Kingdom

Not yet recruiting

Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage (RESTARTtlCrH)

Traumatic Intracranial Haemorrhage
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Adebrelimab and a TKI in Combination With GEMOX in First-line Treatment of Advanced Biliary Tract Cancers (BTC)

Biliary Tract Cancer | Gemox Chemotherapy

China
Taizhou Hospital

Not yet recruiting

High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases

Lung Cancer, Nonsmall Cell
Hadassah Medical Organization

Recruiting

Using Chronobiology to Improve Lenvatinib Efficacy

Lenvatinib Treatment

Israel
Hospices Civils de Lyon

Not yet recruiting

Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy (PHENO SMART)

Spinal Muscular Atrophy

France
Ascentage Pharma Group Inc.

Recruiting

A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.

CLL/SLL

China
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
Hyogo Medical University
Merck Sharp & Dohme LLC

Not yet recruiting

Study of Pembrolizumab Plus Chemotherapy With Lenvatinib for Malignant Pleural Mesothelioma (PENINSULA)

Malignant Pleural Mesothelioma

Japan
Istituto Auxologico Italiano

Recruiting

Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases (ALS-PHENO)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Italy
National Cancer Institute (NCI)

Recruiting

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia

United States
Istituto Auxologico Italiano
Azienda Ospedaliera Città della Salute e della Scienza di Torino; Ospedale...

Recruiting

Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis (DRIVEALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis

Italy
Peking University First Hospital

Recruiting

Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy

Renal Cell Carcinoma, Clear Cell, Somatic

China
M.D. Anderson Cancer Center

Recruiting

Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer

Triple Negative Breast Cancer | Stage 1 cT1b-T1cN0M0

United States
MedRegen LLC

Not yet recruiting

MRG-001 in Patients With Amyotrophic Lateral Sclerosis

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Lou Gehrig Disease | Motor Neuron Atrophy

Search clinical trials for: SMN protein depletion

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