Search clinical trials for: Severe

Total 8561 results

NEXTGEN Bioscience

Not yet recruiting

Safety and Efficacy of Oral NXC-736 in Adult Participants With Severe Alopecia Areata

Alopecia Areata
Amgen

Recruiting

A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Sjogren's Syndrome

Israel, Chile, United States, Argentina, Canada, Japan, Korea, Republic of
Studio Dentistico Associato Sivolella

Recruiting

"Tunnel" Flap vs Trapezoidal Flap for Lateral Sinus Lift

Severe Atrophy of the Edentulous Maxilla

Italy
Institut National de la Santé Et de la Recherche...

Not yet recruiting

Genetic Susceptibility to Severe Infections (PREDISPOSITI)

Infectious Disease
Sheba Medical Center

Recruiting

"Hachi Barie" Project - A Multidisciplinary Program to Accompany Severely Obese Teenagers in the Weight Loss Process for the Benefit of Their Recruitment Into the Israel Defense Forces

Morbid Obesity

Israel
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR)

Aortic Regurgitation

China
Harvard School of Public Health (HSPH)
Muhimbili University of Health and Allied Sciences

Not yet recruiting

Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania

Neonatal Infection

Tanzania
Beijing Tiantan Hospital

Recruiting

Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury (MERCURY)

Brain Injuries, Traumatic | Subarachnoid Hemorrhage | Cerebral Hemorrhage | Intracranial Pressure

China
Sanofi

Recruiting

Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma (AIRCULES)

Asthma

Turkey, Argentina, India, Israel, Korea, Republic of, United States, Chile, Japan
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611 in Chinese Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

China
Region Skane
Department of Psychology. Lund University.; Department of Clinical Sciences...

Recruiting

Intractable Self-harm-What Support is Effective?

Self-harm

Sweden
Sanofi
Regeneron Pharmaceuticals

Recruiting

Observational Study of Canadian Patients (6 Years or Older) Receiving Dupixent® for Moderate to Severe Atopic Dermatitis (CANDID)

Moderate to Severe Atopic Dermatitis

Canada
Temple University
BioXcel Therapeutics Inc

Recruiting

Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar Disorder

Bipolar Disorder | Dexmedetomidine | Schizo Affective Disorder | Schizophrenia Agitation

United States
TriFlo Cardiovascular, Inc.

Not yet recruiting

Transcatheter Treatment of Tricuspid Valve Regurgitation

Symptomatic Severe Tricuspid Regurgitation

Italy
University Hospital, Lille

Not yet recruiting

Clinical and Objective Psychiatric Analyses in Severe Depression. (CALYPSO)

Depression
Abalonex, LLC

Not yet recruiting

Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Brain Injury

Traumatic Brain Injury | Cerebral Edema
Akeso

Not yet recruiting

A Phase II Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
University Hospital, Lille

Not yet recruiting

Severe Congenital Hemostatic Defects, Cerebral MIcrobleeds and COGnition (HEMICOG)

Cerebral Microbleeds, Congenital Haemophilia, Congenital Von Willebrand Disease
Kasr El Aini Hospital

Recruiting

Comparison of Ketamine Plus Dexamethasone Versus Ketamine Alone for Prevention of Severe Shivering After Spinal Anesthesia in Cesarean Section

Intraoperative Shivering | Severe Shivering | Ketamine With Shivering | Dexamethasone for Shivering

Egypt
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Takeda

Recruiting

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment

Plaque Psoriasis

United States, Canada, Poland, Italy, Japan
IGM Biosciences, Inc.

Recruiting

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

Arthritis | Arthritis, Rheumatoid | Rheumatoid Arthritis

United States, Poland
Sunnybrook Health Sciences Centre

Not yet recruiting

Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments (PCS-HBOT)

COVID-19 | Fatigue | Fatigue Syndrome, Chronic | Post-COVID-19 Syndrome | Post COVID-19 Condition | Post-COVID Syndrome

Canada
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Stanford University
Boston Children's Hospital; Duke University

Not yet recruiting

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cardiogenic Shock
Pfizer
Kaiser Permanente

Recruiting

A Study to Learn About ABRYSVO Vaccine in Older Adults to Prevent Severe Respiratory Syncytial Virus (RSV) Infection.

Respiratory Syncytial Viruses

United States
Hansoh BioMedical R&D Company

Recruiting

A Study to Evaluate Efficacy and Safety of HS-10374 for Moderate to Severe Plaque Psoriasis

Psoriasis

China
Nanjing Chia-tai Tianqing Pharmaceutical

Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of Elagolix Tablets in Women With Moderate or Severe Endometriosis-associated Pain

Endometriosis

China
Guizhou Provincial People's Hospital

Recruiting

the Difference of Follow-up Methods of Neonatal Jaundice (NJFU)

Neonatal Jaundice

China
Bristol-Myers Squibb

Recruiting

A Post-Marketing Surveillance Study to Assess Safety of Ozanimod in Patients With Moderate to Severe Active UC in Korea

Ulcerative Colitis

Korea, Republic of
Lithuanian University of Health Sciences

Recruiting

Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease

Cardiovascular Diseases | Quality of Life | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Lithuania
Massachusetts General Hospital
National Institute of Nursing Research (NINR); Dana-Farber Cancer Institute; University... and other collaborators

Not yet recruiting

The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial (PQ-ResPOND)

Pain | Disabilities Multiple | Cerebral Palsy Infantile
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Role of Vitamin D in Prevention of Dengue Haemorrhagic Fever and Dengue Shock Syndrome

Dengue Fever

Bangladesh
University Hospital, Strasbourg, France

Not yet recruiting

Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases (SeeMyLife)

Quality of Life | Eye Diseases | Blindness | Severe Loss of Vision

France
Peking University People's Hospital

Recruiting

The Optimization of Conditioning Regimen for HLA Matched HSCT in SAA

Severe Aplastic Anemia

China
Assiut University

Not yet recruiting

Assessment of Right Ventricular Function in Patients With Severe Mitral Stenosis Before and After Balloon Mitral Valvuloplasty

Mitral Stenosis
National and Kapodistrian University of Athens

Recruiting

Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma (MepoRiNaPAs)

Chronic Rhinosinusitis With Nasal Polyps | Chronic Rhinosinusitis Without Nasal Polyps | Severe Eosinophilic Asthma

Greece
University Hospital of Ferrara

Recruiting

Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study) (CAUSATIVE)

Aortic Stenosis, Severe | Amyloidosis Cardiac

Italy
Tang-Du Hospital

Not yet recruiting

Baricitinib for Moderate and Severe Traumatic Intracerebral Hemorrhage/Contusions

Traumatic Brain Injury

China
Institute of Tropical Medicine, Belgium
KU Leuven; Leiden University Medical Center; Barcelona Institute for Global Health and other collaborators

Recruiting

Host Immune and Metabolic Determinants of Sexual Conversion in Plasmodium Parasites IMMETASEX (IMMETASEX)

Uncomplicated Malaria | Severe Malaria | Asyptomatic Plasmodium Infection

Mozambique, Belgium, Burkina Faso
AbbVie

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.

Crohn's Disease

United States, Canada, Israel, Taiwan, Japan, Korea, Republic of
Beijing Chao Yang Hospital

Recruiting

Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO

Extracorporeal Membrane Oxygenation | Acute Respiratory Distress Syndrome | Mechanical Power | Transpulmonary Mechanical Power

China
University of Texas Southwestern Medical Center

Recruiting

Ketamine in Severe Traumatic Brain Injury

Traumatic Brain Injury | Traumatic Encephalopathy

United States
Northwestern University
University of Alabama at Birmingham; University of Southern California; Medical... and other collaborators

Not yet recruiting

FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial

Moderate to Severe Traumatic Brain Injury
Akeso

Recruiting

To Evaluate the Efficacy and Safety of AK111 Injection in the Treatment of Moderate to Severe Plaque Psoriasis

Skin Diseases | Psoriasis

China
Action Against Hunger USA
University of Washington; Ethiopian Public Health Institute

Not yet recruiting

Modified Dosage for Severe Acute Malnutrition (MODAM-SAM)

Severe Acute Malnutrition
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Effect of Patient Management Based on Continuous Continuous Glucose Monitoring on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes and Moderate to Severe Coronary Artery Stenosis

Diabetes Mellitus, Type 2 | Major Adverse Cardiac Events

China
Sanofi
Kymera Therapeutics, Inc.

Recruiting

Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic Dermatitis (ADVANTA)

Atopic Dermatitis

Greece, Poland, United States, Germany
Brexogen Inc.

Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single-dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States
Brexogen Inc.

Not yet recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Repeated-dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

Search clinical trials for: Severe

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