Search clinical trials for: TOCI

Total 523 results

Hoffmann-La Roche

Completed

A Study to Evaluate Pharmacokinetics and Safety of Tocilizumab (RoActemra/Actemra) in Participants Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis (sJIA)

Juvenile Idiopathic Arthritis

Belgium, Canada, United States, Argentina, Poland, Spain, Germany, Hungary
Hoffmann-La Roche

Completed

Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

Serbia, Germany, France, Russian Federation, Italy, Tunisia
Tianjin Medical University General Hospital

Completed

Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders (TANGO)

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorders

China
Odense University Hospital
University of Southern Denmark

Unknown

The Diagnostic Value of PET/MRI in Head and Neck Cancer

Head and Neck Neoplasms | Squamous Cell Carcinoma of Head and Neck | Lymph Node Metastases

Denmark
University of Erlangen-Nürnberg Medical School

Completed

Comparing the Efficacy of Periarticular Bone Structure in Patients Treated With Either Tocilizumab or Tumor Necrosis Factor Blockers (Re-Bone)

Rheumatoid Arthritis

Germany
University Hospital, Strasbourg, France

Completed

Efficacy of Tocilizumab in Primary Sjögren's Syndrome. (ETAP)

Primary Sjögren's Syndrome (pSS)

France
Ablynx

Completed

A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Czechia, Bulgaria, Germany, Mexico, Poland, Romania, Serbia, Spain, Hungary, United States, Belgium, Georgia, Moldova, Republic of, North Macedonia
Assistance Publique - Hôpitaux de Paris
Hoffmann-La Roche

Completed

Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis (TIDOA)

Hand Osteoarthritis

France
University of California, Los Angeles
Genentech, Inc.

Completed

Musculoskeletal Ultrasound in Predicting Early Dose Titration With Tocilizumab (RASTS)

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

A Long Term Extension Study of WA19926 (NCT01007435) of Tocilizumab (RoActemra/Actemra) in Participants With Early, Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Brazil
Hoffmann-La Roche

Completed

An Observational Study on Long-Term Efficacy and Safety of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis (FAct)

Rheumatoid Arthritis

Netherlands
Hoffmann-La Roche

Completed

Tocilizumab Real-Life Human Factors (RLHFs) Validation Study

Rheumatoid Arthritis

United States
Hoffmann-La Roche

Completed

EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
Hospices Civils de Lyon

Completed

TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONE (TOCIDYS)

Fibrous Dysplasia of Bone

France
Mycenax Biotech Inc.

Completed

Phase I, Pharmacokinetic, Safety and Tolerability Study in Healthy Volunteers

Pharmacokinetics

Australia
NYU Langone Health
Genentech, Inc.

Terminated

Tocilizumab for the Treatment of Behcet's Syndrome

Behcet Syndrome

United States
University Hospital Inselspital, Berne
Roche Pharma AG; University of Bern

Completed

Tocilizumab for Patients With Giant Cell Arteritis

Giant Cell Arteritis

Switzerland
Eric B. Suhler
Genentech, Inc.

Terminated

Tocilizumab in the Management of Juvenile Idiopathic Arthritis Associated Uveitis

Juvenile Idiopathic Arthritis Associated Uveitis

United States
Association Aquitaine de Recherche Clinique en...
Roche Pharma AG; Chugai Pharma France

Completed

Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation (Tocihelper)

Arthritis, Rheumatoid | Tocilizumab | T-Lymphocytes, Helper-Inducer

France
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Tel-Aviv Sourasky Medical Center
Amsterdam Rheumatology and Immunology Center

Unknown

Therapeutic Drug Monitoring of Tocilizumab in Rheumatoid Arthritis

Rheumatoid Arthritis | Tocilizumab

Israel
Hoffmann-La Roche

Completed

Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment (CONIFER)

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent (ACT-MOVE)

Rheumatoid Arthritis

United Kingdom
Fundació Institut de Recerca de l'Hospital de la...

Completed

Immunoregulatory Mechanisms of Treg Cells Induced by Tocilizumab

Arthritis,Rheumatoid

Spain
Hoffmann-La Roche

Completed

A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic Therapy (TOSCA)

Rheumatoid Arthritis

France
Hoffmann-La Roche

Terminated

A Study of the Efficacy and Safety of Tocilizumab for Confirmed Rheumatoid Arthritis (RA) Participants in Clinical Practice

Rheumatoid Arthritis

Saudi Arabia
Washington University School of Medicine

Terminated

Allogeneic or Haploidentical Stem Cell Transplant Followed By High-Dose Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

United States
Hoffmann-La Roche

Completed

A Non-Interventional Study of Rheumatoid Arthritis Patients Treated With RoActemra/Actemra (Tocilizumab) in Monotherapy

Rheumatoid Arthritis

Belgium
Hoffmann-La Roche

Completed

A Comparative Study to Observe the Effect of Concomitant Use of Corticosteroid Treatment in Rheumatoid Arthritis (RA) Participants Who Are Treated With a Tumor Necrosis Factor (TNF) Inhibitor or Tocilizumab (TCZ) as Their Second Biological Treatment.

Rheumatoid Arthritis

Sweden
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
Hoffmann-La Roche
nv Roche sa

Completed

An Observational Study to Evaluate the Clinical Effectiveness, Quality of Life, Safety and Tolerability of Tocilizumab (TCZ) in Patients With Rheumatoid Arthritis (RA) in Daily Clinical Practice

Rheumatoid Arthritis

Belgium, Luxembourg
Hoffmann-La Roche

Completed

U-Act-After: An Observational Study on Long-Term Efficacy of Tight Control RoActemra/Actemra (Tocilizumab) and/or Methotrexate in Patients With Early Rheumatoid Arthritis Who Have Participated in the U-Act-Early Study (ML22497)

Rheumatoid Arthritis

Netherlands
Papworth Hospital NHS Foundation Trust
Roche Pharma AG; National Institute for Health Research, United Kingdom

Completed

A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension (TRANSFORM-UK)

Pulmonary Arterial Hypertension

United Kingdom
Simon Krabbe
Zealand University Hospital; University of Aarhus; University of Southern Denmark

Completed

Predicting Hospitalized Infection in Patients With Chronic Inflammatory Arthritis Treated With Biological Drugs

Rheumatoid Arthritis | Psoriatic Arthritis | Spondyloarthritis
Hoffmann-La Roche

Completed

A Study of Subcutaneous (SC) Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis (RA) and Inadequate Response to Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

Rheumatoid Arthritis

Denmark, Finland, Norway, Sweden
Hoffmann-La Roche

Completed

A Study of Tocilizumab Plus Non-biological DMARD in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Non-biological DMARDs

Rheumatoid Arthritis

Portugal
Hoffmann-La Roche

Completed

A Study of Tocilizumab Added to DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to DMARDs.

Rheumatoid Arthritis

Russian Federation
Hoffmann-La Roche

Completed

A Prospective, Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Lebanon, Kuwait, Qatar, United Arab Emirates
Hoffmann-La Roche

Completed

A Phase IV Study to Evaluate the Effect of Subcutaneous (SC) Tocilizumab Administered to Participants With Rheumatoid Arthritis (RA) Assessed Using Disease Activity Score (DAS28)

Rheumatoid Arthritis

Slovakia
Centre Hospitalier Universitaire de Besancon

Completed

Evolution of Adipokines and Body Composition in Rheumatoid Arthritis Patients Receiving Tocilizumab Therapy (ADIPRAT)

Arthritis, Rheumatoid

France
Hoffmann-La Roche

Terminated

An Extension Study to WA19977 in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Russian Federation, Poland
Hoffmann-La Roche

Terminated

A Long-Term Extension Study to WA19926 (NCT01007435) of Tocilizumab in Participants With Early, Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Poland
Hoffmann-La Roche

Completed

A Study of Subcutaneous RoActemra/Actemra (Tocilizumab) as Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, Portugal, Ireland
Hospital for Special Surgery, New York
Genentech, Inc.

Completed

Study of Tocilizumab to Treat Polymyalgia Rheumatica

Polymyalgia Rheumatica (PMR)

United States
Hoffmann-La Roche

Completed

Multicenter, Post-marketing, Non-interventional, Observational Study in RA Patients Treated With RoActemra/Actemra (Tocilizumab)

Rheumatoid Arthritis

China
University of British Columbia

Completed

The Effect of Sham Feeding on Small Bowel Transit Time in Patients Undergoing Capsule Endoscopy

Slow Transit

Canada
Hoffmann-La Roche

Completed

A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX

Rheumatoid Arthritis

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Randomized Trial Comparing Efficacy of Adalimumab, Anakinra and Tocilizumab in Non-infectious Refractory Uveitis (RUBI)

Uveitis | Biotherapy

France
Centre Hospitalier Universitaire Dijon

Completed

Evaluation of Tocilizumab as an add-on Therapy to Corticoids in Giant Cell Arteritis: Proof of Concept Study. (HORTOCI)

Giant Cell Arteritis

France

3

Subscribe