Search clinical trials for: autologous Tumor

Total 35736 results

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Unknown

CD276 CAR-T for Patients With Advanced CD276+ Solid Tumors

Solid Tumor | CAR

China
Universitair Ziekenhuis Brussel

Active, not recruiting

Intratumoral Injection of Autologous CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Talimogene Laherparepvec (T-VEC) (myDCTV)

Melanoma

Belgium
Universitair Ziekenhuis Brussel

Completed

Intratumoral Injection of Autologous CD1c (BDCA-1)+ myDC, Avelumab, and Ipilimumab Plus Systemic Nivolumab (myDAvIpNi)

Solid Tumor | Metastases to Soft Tissue

Belgium
Adaptimmune

Completed

MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers

Melanoma | Head and Neck Cancer | Urothelial Carcinoma | Bladder Urothelial Carcinoma

United States, Canada, Spain
Oncovir, Inc.
National Cancer Institute (NCI); University of Missouri-Columbia; Icahn School... and other collaborators

Completed

In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol® (Poly-ICLC)

Melanoma | Sarcoma | Head and Neck Cancer | Non-Melanoma Skin Cancers

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies

Diffuse Large B-Cell Lymphoma | Burkitt Lymphoma | Mantle Cell Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma | CD20-Positive Neoplastic Cells Present | Refractory Mature B-Cell Non-Hodgkin Lymphoma

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

Adult Diffuse Astrocytoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Tumor | Adult Oligoastrocytoma

United States
Kang YU
CARsgen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors

Hepatocellular Carcinoma | B Cell Lymphoma | Pancreatic Carcinoma | Myeloma | B Cell Leukemia | Adenocarcinoma of Esophagogastric Junction

China
The Second Hospital of Shandong University
Shandong Sunstem Biotechnology Co.,Ltd.

Unknown

Safety and Efficacy Study for MG-7-DC Vaccine in Gastric Cancer Treatment

Gastric Cancer

China
CAR-T (Shanghai) Cell Biotechnology Co., Ltd.
Eastern Hepatobiliary Surgery Hospital

Unknown

A Clinical Study in Patients With High-risk Recurrent Primary Hepatocellular Carcinoma Using Autologous TILs

Hepatic Carcinoma

China
Inge Marie Svane

Unknown

Adoptive Cell Therapy Across Cancer Diagnoses

Cancer

Denmark
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Young Patients Who Are Undergoing Surgery for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
National Institutes of Health (NIH)

Completed

Vaccine Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
Bristol-Myers Squibb; Northwest Biotherapeutics; Brain Tumor Funders Collaborative

Withdrawn

Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen Vaccine and Nivolumab in Treating Patients With Recurrent Glioblastoma

Gliosarcoma | Recurrent Glioblastoma | Oligodendroglioma | Small Cell Glioblastoma | Giant Cell Glioblastoma

United States
Jonsson Comprehensive Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Eunice Kennedy Shriver... and other collaborators

Completed

Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1 (NYM)

Childhood Solid Neoplasm | Metastatic Neoplasm | Adult Solid Neoplasm

United States
Northwestern University

Terminated

Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial (DIScl2011)

Scleroderma, Systemic

United States
National Cancer Institute (NCI)

Terminated

Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer

Melanoma | Colon Cancer | Gastrointestinal Cancer | Hepatocellular Cancer | Genitourinary Cancer

United States
CytoVac A/S

Completed

Autologuos Lymphoid Effector Cells Specific Against Tumour (ALECSAT) as Add on to Standard of Care in Patients With Glioblastoma (ALECSAT)

Glioblastoma

Sweden
Istituto Scientifico Romagnolo per lo Studio e...

Terminated

Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients. (ACDC)

Malignant Melanoma | Adjuvant Drug Therapy | Vaccin Therapy

Italy
Henan Cancer Hospital

Terminated

Autologous Cytokine-induced Killer Cells Combined Chemotherapy in Advanced Pancreatic Cancer

Advanced Cancer

China
Gary Archer Ph.D.
Bristol-Myers Squibb; Duke Cancer Institute

Completed

Nivolumab With DC Vaccines for Recurrent Brain Tumors (AVERT)

Glioblastoma | Astrocytoma | Malignant Glioma

United States
Samsung Medical Center
KSPNO stem cell transpantation committee

Unknown

High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors

Brain Tumor

Korea, Republic of
M.D. Anderson Cancer Center
Miltenyi Biotec B.V. & Co. KG

Completed

Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Cytomegalovirus (CMV) Reactivation

Lymphoma | Leukemia

United States
Safe Save Medical Cell Sciences & Technology Co...

Unknown

ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

Taiwan
Mary Crowley Medical Research Center

Terminated

Phase I Trial of TGFB2-Antisense-GMCSF Gene Modified Autologous Tumor Cell (TAG) Vaccine for Advanced Cancer (Auto TAG)

Carcinoma, Advanced Metastatic

United States
Craig L Slingluff, Jr

Completed

Pilot Study for the Evaluation of the Efficacy of Vaccination With Autologous Tumor Cells Plus Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) - in - Adjuvant, Followed by Systemic Low-dose-interleukin-2 (IL-2) Administration, in Patients With High Risk Melanoma (MEL37)

Melanoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Baxter Healthcare Corporation; Amgen; Nexell Therapeutics Inc

Completed

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

Sarcoma | Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Treatment of B-CLL With Human IL-2 and CD40 Ligand and Plasmid Gene Modified Autologous Tumor Cells (CLIPA)

Leukemia | Leukemia, B-Cell, Chronic

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Autologous Hematopoietic Stem Cell Transplantation as Adjuvant Treatment for Triple Negative Breast Cancer Patients

Triple-Negative Invasive Breast Carcinoma | Residual Tumor

Mexico
Mayo Clinic
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Cryosurgery in Treating Patients With Residual, Relapsed, or Refractory B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Cutaneous B-cell Non-Hodgkin Lymphoma | Small Lymphocytic Lymphoma | Adult Grade III Lymphomatoid... and other conditions

United States
Ronald Levy
National Institutes of Health (NIH)

Completed

Phase 1-2 of a CpG-Activated Whole Cell Vaccine Followed by Autologous Immunotransplant for MCL

Lymphoma, Mantle-Cell

United States
Sellas Life Sciences Group

Unknown

WT1 Analog Peptide Vaccine in Patients With Multiple Myeloma Following Autologous Stem Cell Transplantation

Multiple Myeloma | Minimal Residual Disease | High-Risk Cancer

United States
Guangxi Medical University

Unknown

Adjuvant Therapies for Patients With HCC and MVI (A-TACE/S-HCC)

Hepatocellular Carcinoma

China
Roswell Park Cancer Institute
Iovance Biotherapeutics, Inc.

Withdrawn

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Unresectable Renal Pelvis Urothelial Carcinoma | Unresectable Ureter Urothelial Carcinoma

United States
Samsung Medical Center

Withdrawn

Study to Evaluate the Safety and Efficacy of Sorafenib, in Subject With Refractory Solid Tumors

Refractory Solid Tumors

Korea, Republic of
University of Pennsylvania
University of California, San Francisco

Terminated

Pilot Study of Autologous T-cells in Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer

United States
National Cancer Institute (NCI)

Terminated

Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer

Melanoma | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Gastrointestinal Cancer

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
N.N. Petrov National Medical Research Center of...

Unknown

Autologous Dendritic Cell Vaccine in Patients With Soft Tissue Sarcoma (ADCVCTAST)

Sarcoma | Neoplasms, Connective and Soft Tissue

Russian Federation
University of Maryland, Baltimore
University of Maryland Greenebaum Cancer Center

Completed

Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma

Infection | Multiple Myeloma and Plasma Cell Neoplasm

United States
Siriraj Hospital
Mahidol University

Unknown

The Adoptive Immunotherapy for Solid Tumors Using Modified Autologous Cytokine-induced Killer Cells

Cholangiocarcinoma

Thailand
University of Pennsylvania
University of Maryland, College Park

Completed

Phase I/II Clinical Trial Combining hTERT Tumor Vaccine & Autologous T Cells in Patients With Advanced Myeloma

Multiple Myeloma

United States
Memorial Sloan Kettering Cancer Center

Completed

High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation

Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant

Unspecified Childhood Solid Tumor, Protocol Specific | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Mucositis | Childhood Acute Lymphoblastic Leukemia in Remission | Childhood Chronic Myelogenous... and other conditions

United States, Canada, Australia
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...

Completed

A Phase I Study of Immunotherapy With GSC -Loaded Dendritic Cells in Patients With Recurrent Glioblastoma (DENDR-STEM)

de Novo Glioblastoma
Hadassah Medical Organization

Unknown

Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors

Melanoma | Kidney Cancer | Breast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer

Israel
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors (NEXIRI2)

Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors

France
Walter J. Storkus
National Cancer Institute (NCI)

Completed

Dendritic Cell Vaccines + Dasatinib for Metastatic Melanoma

Metastatic Melanoma

United States
Jan Walewski

Completed

Dendritic Cell Vaccine in Treating Patients With Indolent B-Cell Lymphoma or Multiple Myeloma

Lymphoma | Multiple Myeloma and Plasma Cell Neoplasm

Poland
M.D. Anderson Cancer Center

Terminated

Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma

Neuroblastoma

United States

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