Search clinical trials for: cholinesterase inhibitor

Total 67981 results

Regina Elena Cancer Institute

Unknown

Recovery From Anesthesia After Robotic Assisted Radical Cystectomy

Anesthesiology Management

Italy
Assiut University

Completed

Neostigmine Versus Dexamethasone as Adjuvants to Lidocaine During Intravenous Local Anesthesia

Adjuvants, Anesthesia

Egypt
Dennis Levi

Completed

Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia

Amblyopia

United States
Assiut University
Ghada Mohammed AboelFadl; Abualauon Elbiblawy

Completed

Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery

Postoperative Pain

Egypt
Eisai Co., Ltd.

Completed

A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB)

Lewy Body Disease | Dementia, Lewy Body

Japan
Lawson Health Research Institute

Completed

Donepezil and the Risk of Falls in Seniors With Cognitive Impairment

Mild Cognitive Impairment (MCI) | Gait | Falls | Balance

Canada
B.P. Koirala Institute of Health Sciences

Completed

Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy

Gall Stone Disease

Nepal
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Minimal Invasive Surgery in Total Hip Arthroplasty Patients; Short- and Long Term Results

Hip Osteoarthritis

Norway
Boehringer Ingelheim

Completed

BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.

Alzheimer Disease

United States, Canada, United Kingdom, Germany, Portugal, France, Belgium, Netherlands, Austria, Poland, Italy
Pfizer

Completed

Scopolamine Challenge Study

Healthy

France
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease-

Alzheimer's Disease

Japan
Allergan

Withdrawn

A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Cognitive Enhancement as a Target for Cocaine Pharmacotherapy

Addiction

United States
Attikon Hospital

Completed

Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children

Anesthesia; Functional

Greece
University Hospital, Antwerp

Completed

Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex (SUDIA)

Muscle Weakness | Muscle Fatigue | Diaphragmatic Dysfunction

Belgium
Mansoura University

Unknown

Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine

Supratentorial Brain Tumor Surgery
Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)

Dementia | Alzheimer's Disease
Tetra Discovery Partners

Completed

Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers

Alzheimer Disease

United States
Merck Sharp & Dohme LLC

Completed

Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)

Alzheimer's Disease
Seoul National University Bundang Hospital

Completed

Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery

Neuromuscular Block, Residual

Korea, Republic of
Amsterdam UMC, location VUmc
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Terminated

Cholinesterase Inhibitors to Slow Progression of Visual Hallucinations in Parkinson&Apos;s Disease (CHEVAL)

Parkinson's Disease

Netherlands
Eisai Inc.
Pfizer

Completed

The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility

Mild to Severe Alzheimer's Disease

United States
Corium, Inc.

Completed

A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System

Skin Irritation | Sensitization

United States
Corium, Inc.

Completed

A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS)

Alzheimer's Disease

United States
Wake Forest University

Completed

Epidural Neostigmine for Labor Pain

Labor Pain

United States
Wake Forest University
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

Chronic Low Back Pain | Diabetic Neuropathic Pain

United States
Washington University School of Medicine
Northwestern University

Completed

Corticolimbic Degeneration and Treatment of Dementia

Dementia
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Factors That Affect Aricept Medication Persistence Rate and the Safety and Efficacy in Patients With Alzheimer's Disease in Clinical Practice

Alzheimer's Disease

Japan
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease

Alzheimer's Desease

Japan
Regina Elena Cancer Institute

Completed

Quality of Awakening and Impact on Cognitive Function After Administration of Sugammadex in Robotic Radical Cystectomy

Anesthesiology Management

Italy
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Rivastigmine BA Trial With Multiple Application of Transdermal Patches, Adaptation and Tapering Phase

Bioequivalence

Germany
Ewha Womans University

Completed

Ceramic-on-Ceramic Versus Ceramic-on-HXLPE THA

Osteoarthritis, Hip | Arthropathy of Hip | Avascular Necrosis of the Femoral Head | Hip Arthr
Landspitali University Hospital
Mentis Cura

Unknown

EEG-cholinergic Index and Clinical Response to Treatment With Cholinesterase Inhibitors (Cholindex)

Alzheimer´s Disease
Vanderbilt University Medical Center

Withdrawn

Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study (RDVCGH)

Oxidative Stress | Insulin Sensitivity

United States
Corium, Inc.

Completed

A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations

Alzheimer's Disease

United States
Asan Medical Center
Seoul St. Mary's Hospital; Seoul National University Bundang Hospital; Eisai... and other collaborators

Completed

Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mg (ODESA)

Alzheimer's Disease

Korea, Republic of
Corium, Inc.

Completed

A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®

Alzheimer Disease

United States
Corium, Inc.

Completed

A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®

Alzheimer's Disease

United States
GlaxoSmithKline

Completed

Study of SB-742457 or Donepezil Versus Placebo in Subjects With Mild-to-moderate Alzheimer's Disease

Alzheimer's Disease

Bulgaria, Estonia, Korea, Republic of, Germany, Greece, Czechia, South Africa, Russian Federation, Poland, Chile, Mexico
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Dementia With Lewy Body Disease

Japan
Campus Bio-Medico University

Unknown

Role of Curarization During Anesthesia for Gynecologic Surgical Laparotomy Procedures

Curarization, Postoperative Residual

Italy
Campus Bio-Medico University

Unknown

Role of Curarization During Anesthesia for Gynecologic Surgical Laparoscopic Procedures

Curarization, Postoperative Residual

Italy
New York State Psychiatric Institute
United States Department of Defense

Completed

Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil

Mild Cognitive Impairment

United States
Porter Adventist Hospital

Terminated

Donepezil Memory Preservation Post ECT

Memory Impairment

United States
KK Women's and Children's Hospital
Singhealth Foundation

Completed

Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological Surgery

Postoperative Nausea and Vomiting

Singapore
American University of Beirut Medical Center

Completed

"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"

Anesthesia Recovery

Lebanon
Associação Fundo de Incentivo à Pesquisa

Unknown

Donepezil, Residual Excessive Daytime Sleepiness, Obstructive Sleep Apnea

OSA | Sleepiness

Brazil
Chong Kun Dang Pharmaceutical

Completed

CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)

Central Nervous System Diseases

Korea, Republic of
Federal University of Minas Gerais

Completed

Good Rate of Clinical Response to Cholinesterase Inhibitors in Alzheimer's Disease After Three Months of Treatment (NINDS-AIREN)

Late Onset Alzheimer

3

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