Search clinical trials for: drug half life

Total 273391 results

Yale University
Irrimax Corporation

Recruiting

Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life

Urinary Retention | Neurogenic Bladder

United States
Universidad Autonoma de Nuevo Leon
LifeNet Health; Lynch Biologics LLC

Recruiting

Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft

Periodontal Diseases

Mexico
ACADIA Pharmaceuticals Inc.

Recruiting

ACP-204 in Adults With Alzheimer's Disease Psychosis

Alzheimer's Disease Psychosis

Taiwan, United States, Korea, Republic of
Auburn University

Recruiting

Improving Metabolic & Mental Health in Female Healthcare Shift Workers

Overweight and Obesity | Healthy Lifestyle | Work Related Stress | Sleep, Inadequate

United States
Novartis Pharmaceuticals

Recruiting

Assessment of the Quality of Life of Multiple Sclerosis Patients Treated With Ofatumumab in Real-life in France (SEPROS)

Multiple Sclerosis (MS)

France
Sakarya University

Recruiting

The Effect of Staple Line Reinforcement Procedures on Postoperative Nausea and Vomiting in Sleeve Gastrectomy

Nausea, Postoperative | Vomiting, Postoperative | Bariatric Surgical Procedures

Turkey
Qatar University
Cairo University; NYU Langone Health; Mahidol University; Jordan University of... and other collaborators

Recruiting

Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis

Irreversible Pulpitis

Qatar
Fonds de Dotation HTC Project
Pfizer; Gilead Sciences; Novartis Pharmaceuticals; University Hospital, Clermont-Ferrand and other collaborators

Recruiting

Evaluation of the Impact of the Use of NewSpringForMe on Transplanted Patients' Quality of Life and Support (NSFM)

Hematologic Diseases | Bone Marrow Transplantation | Hematopoietic Stem Cell Transplantation

France
Pontificia Universidad Catolica de Chile

Recruiting

Comparison of the Effect of Two Interventions on Liver Frailty Index in Pre-frail and Frail Cirrhotic Patients Enlisted for Liver Transplantation

Cirrhosis, Liver

Chile
MindAhead UG
University Medical Center Göttingen

Recruiting

Efficacy of MindAhead's Digital Behavioral Activation Therapy in Adults With MCI or Mild Dementia

Mild Cognitive Impairment | Mild Dementia

Germany
Wei Gao

Not yet recruiting

Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation

Liver Transplant; Complications | Immunosuppression | Immune Tolerance

China
Purpose Life Sciences

Not yet recruiting

Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents (REVIVE)

Long COVID

Pakistan
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Korea, Republic of, United States, Brazil, Japan, Spain, Argentina, Hungary, Poland, United Kingdom, Australia, Taiwan, Canada, Germany
University of Colorado, Denver
Icahn School of Medicine at Mount Sinai; Ohio State University; Joslin Diabetes...

Recruiting

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life (PROMISE)

Type 1 Diabetes | Pregnancy in Diabetic

United States
Tanta University

Recruiting

Sulfasalazine in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Egypt
Novo Nordisk A/S

Recruiting

A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

Obesity | Type 2 Diabetes | Chronic Kidney Disease

United States, Spain, Poland, Thailand, India, France, Argentina, Canada, Japan, Greece, Slovakia, Hungary, Brazil
Novo Nordisk A/S

Recruiting

A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight

Obesity

United States
Sanofi Pasteur, a Sanofi Company

Recruiting

Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents

Healthy Volunteers | Meningococcal Infection | Meningococcal Immunisation

United States, Puerto Rico
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate Efficacy of EB-PA as Protein Amplifier for Skeletal Muscle Strength & Growth

Skeletal Muscle Strength & Growth

India
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Ulcerative Colitis and Their Infants

Ulcerative Colitis

United States
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease

Korea, Republic of, United States, Belgium, Canada, Chile, China, Greece, Hungary, Mexico, Peru, Poland, Switzerland, Turkey, United Kingdom
University of British Columbia

Recruiting

Characterizing the Cerebrovascular Physiology of Circulatory Death During Withdrawal of Life Sustaining Therapies in Humans (EVALUATE)

Circulatory Arrest

Canada
Northumbria University

Recruiting

Low-dose Maximal-intent Versus Controlled-tempo Resistance Training on Quality-of-life in Older Adults

Quality of Life

United Kingdom
AbbVie

Recruiting

A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain (PROVIDENCE)

Chronic Lymphocytic Leukemia

Spain
Sanofi

Recruiting

Proof-of-concept Study Evaluating Subcutaneous Amlitelimab in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis

Chile, Germany, Poland, Canada, Spain, United States, Australia, Portugal, Hungary, Italy, France
RenJi Hospital

Not yet recruiting

Incremental PD With Single Icodextrin Exchange

Survival | Health-related Quality of Life | Peritoneal Dialysis Complication | Residual Kidney Function
Elpen Pharmaceutical Co. Inc.

Not yet recruiting

TorasEmide Induced Effect on Quality of Life and Clinical parameterS in paTients With chronIc heArt Failure Receiving Eplerenone. (ESTIA)

Chronic Heart Failure
Assiut University

Not yet recruiting

Insulin Therapy in Type 2 Diabetic Patients: Real-life Study on Effectiveness and Satisfaction

Diabete Type 2
Medisch Spectrum Twente
Foothills Medical Centre

Recruiting

RCT on T-REX Twente Regimen Effects on Quality of Life and Mobilisation for Cardiac Surgery Patients After Sternotomy (T-REX Twente)

Cardiovascular Diseases | Quality of Life | Surgery | Physical Inactivity | Sternotomy

Netherlands
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Prevention of Frailty With Fisetin and Exercise (PROFFi) in Breast Cancer Survivors (PROFFi)

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Early Stage Breast Carcinoma | Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) v8

United States
Sidekick Health

Recruiting

Digital Health Program With Participants Using an Autoinjector

Immune-Mediated Inflammatory Disease

Iceland
Eli Lilly and Company

Recruiting

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor (ACHIEVE-5)

Type 2 Diabetes

United States, Japan, China, Puerto Rico, Romania, Brazil
Jules Bordet Institute

Recruiting

Molecular Imaging of FAP Expressing Cancer-associated Fibroblasts in NSCLC Treated With Immune-checkpoint Inhibitors (LIFE)

Non Small Cell Lung Cancer

Belgium
Centro di Riferimento Oncologico - Aviano

Not yet recruiting

The Impact of Adverse Events, Produced by Antibodies Conjugates, on Quality of Life in Patients With Metastatic Breast Cancer: Multicentric, Observational Study (EVA). (EVA)

Metastatic Breast Cancer

Italy
Medical College of Wisconsin

Not yet recruiting

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

Breast Cancer

United States
Valneva Austria GmbH

Recruiting

A Phase 2 Clinical Study of VLA1553 in Healthy Children Aged 1 to 11 Years

Chikungunya Virus Infection

Dominican Republic, Honduras
Stephen Ruedrich
Neurocrine Biosciences

Not yet recruiting

Valbenazine Treatment of Tardive Dyskinesia in Adults With Intellectual/Developmental Disabilities (TD-AIDD)

Intellectual Disability | Developmental Disabilities | Tardive Dyskinesia

United States
Newark Beth Israel Medical Center
Genentech, Inc.

Not yet recruiting

Health-Related Quality of Life Outcomes and Bleeding Rates Among Patients With Severe Hemophilia A on Emicizumab (ML43518)

Hemophilia A

United States
Coordinación de Investigación en Salud, Mexico

Recruiting

"Pulmonary Rehabilitation Program in Patients With Interstitial Lung Disease Associated With Systemic Sclerosis"

Systemic Sclerosis Associated Interstitial Lung Disease

Mexico
Laboratoire de la Mer
Slb Pharma

Not yet recruiting

PMCF to Assess Real-life Usage Effectiveness, Safety and Patient Satisfaction of a Range of Hypertonic Seawater-based Decongestant Nasal Sprays

Allergic Rhinitis | URTI
Polish Academy of Sciences

Recruiting

Epigenetic Memory of Vitamin D Supplementation (VitDPAS)

Infections | Immune System Diseases | Healthy Lifestyle

Poland
Cardiology Research UBC

Recruiting

MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study (MYCOVACC)

Myocarditis | Pericarditis | Myocarditis Acute | Pericarditis Acute

Canada
University of Toronto

Recruiting

Low Concentration Local Anesthesia Fascia Iliaca Block for Total Hip Arthroplasty (HALF)

Arthroplasty, Replacement, Hip

Canada
Hamilton Health Sciences Corporation
McMaster University

Recruiting

Chronic Cancer Pain Management Program (ICMP)

Breast Cancer | Cancer, Treatment-Related | Pain Cancer

Canada
Gilead Sciences
HIV Prevention Trials Network

Recruiting

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102) (PURPOSE 3)

Pre-Exposure Prophylaxis of HIV Infection

United States
Merck Sharp & Dohme LLC

Recruiting

A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Hyaluronidase (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11)

Melanoma | Renal Cell Carcinoma | Non-Small Cell Lung Cancer

Poland, United States, Argentina, Chile, Japan, Australia, France, New Zealand, South Africa, Turkey
Chiesi Italia
Gesellschaft für Therapieforschung mbH

Recruiting

Observational Study on Therapy Pathways of Asthamics Treated With ICS/LABA/LAMA Therapy in a Real-world Setting (TRIMAXIMIZE)

Asthma

Italy
University Hospital Schleswig-Holstein
SocraMetrics GmbH; Avextra Pharma GmbH

Not yet recruiting

Improvement of Quality of Life by Cannabinoids in Oncologic Patients (BELCANTO)

Quality of Life | Palliative Care | Medical Oncology | Cannabinoids

Germany
National Cancer Institute (NCI)

Recruiting

Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Efficacy and Safety of Neoantigen Peptide Vaccine in the Treatment of Advanced NSCLC Progressed After EGFR-TKI Treatment

NSCLC | EGFR Gene Mutation

China

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