Low-dose Maximal-intent Versus Controlled-tempo Resistance Training on Quality-of-life in Older Adults

Comparison of Two Low-dose Resistance Training Modalities on Strength, Functional Capacity, and Quality-of-life in Healthy, Community-dwelling, Untrained Older Adults: a Randomised Controlled Trial

The aims of this study were to:

1. Compare the effects of low-dose Maximal Intent and Controlled Tempo Resistance Training on untrained healthy older adults' quality-of-life, functional capacity, and strength.
2. Qualitatively explore perceptions of Maximal Intent and Controlled Tempo Resistance Training in older adults.

Older adults are defined as being 60 or more years of age.

Study Overview

• Status: Recruiting
• Conditions: Quality of Life
• Intervention / Treatment: Other: Leg Press Resistance Training (3x5); Other: Leg Press Resistance Training (5x5)

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United Kingdom
  • Tyne And Wear
    • Newcastle, Tyne And Wear, United Kingdom, NE1 8ST
      • Recruiting
      • Northumbria University
      • Sub-Investigator: Gill Barry, PhD
      • Sub-Investigator: Stuart Goodall, PhD
      • Contact: Ashleigh Keenan, MRes; Phone Number: 01912274700; Email: ashleigh.keenan@northumbria.ac.uk
      • Sub-Investigator: Kai T Fox, MRes
      • Sub-Investigator: Ashleigh Keenan, MRes
      • Sub-Investigator: David G Behm, PhD
      • Sub-Investigator: Sam Stuart, PhD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Participants were eligible if they were between 30-60 years old
• Uninjured
• Had no cardiovascular or neuromuscular conditions
• Had not participated in lower-limb resistance training in the previous six months.

Exclusion Criteria:

• Participants were excluded if they had either taken part in any lower-limb resistance training in the last six months
• Had underlying health condition(s) that prevented them from participating in resistance training
• Regularly met or exceeded the UK recommended physical activity guideline of 150-minutes of moderate to intense physical activity per week.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Maximal-intent Resistance Training - 3x5 (MI3x5); The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum.	Other: Leg Press Resistance Training (3x5); Leg Press resistance training at 60% one-rep-max for three sets of five repetitions
Experimental: Maximal-intent Resistance Training - 5x5 (MI5x5); The max-intent group were instructed and encouraged to deliberately commit to exerting maximal effort and force during the concentric phase of the leg press with the intention of achieving the greatest velocity possible. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum.	Other: Leg Press Resistance Training (5x5); Leg Press resistance training at 60% one-rep-max for five sets of five repetitions
Experimental: Controlled-tempo Resistance Training - 3x5 (CT3x5); The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 3 sets of 5 repetitions at 60% one-repetition maximum.	Other: Leg Press Resistance Training (3x5); Leg Press resistance training at 60% one-rep-max for three sets of five repetitions
Experimental: Controlled-tempo Resistance Training - 5x5 (CT5x5); The controlled-tempo group followed a metronome for both eccentric and concentric phases of the leg press with the intention of maintaining a steady three-second concentric and three-second eccentric. This group completed 5 sets of 5 repetitions at 60% one-repetition maximum.	Other: Leg Press Resistance Training (5x5); Leg Press resistance training at 60% one-rep-max for five sets of five repetitions

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Quality-of-life	Participant quality of life (measured through focus group questions & SF-36)	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Balance	Using the biodex to do a 3 x 20s double-foot eyes-open balance test on Level 6.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
6-minute Walk Test	A "brisk"-paced 6-minute walk test.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Timed-up-and-go	Standing from a chair, walking to a point 3 metres away, turn, and return to the chair as quick as possible whilst walking.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
30-second sit-to-stand (30s-Sit-to-Stand)	Maximal amount of repetitions a participant can stand up from a chair in 30-seconds.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength	Participants one-repetition max on leg press machine.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Body Mass Index	Mass and height will be combined to report BMI in kg/m^2	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Strength-to-mass Ratio	Mass and Leg Press 1RM will be combined to calculate strength-to-mass ratio.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.
Leg press one-rep-max velocity pre-to-post	Velocity (m/s) of leg press measured at post-intervention, using baseline one-rep-max.	At baseline and Week 1, mid (Week 4), and post (Week 9), out of a total study duration of 9 weeks.

Collaborators and Investigators

• Sponsor: Northumbria University

Publications and helpful links

General Publications

• Pearson LT, Behm DG, Goodall S, Mason R, Stuart S, Barry G. Effects of maximal-versus submaximal-intent resistance training on functional capacity and strength in community-dwelling older adults: a systematic review and meta-analysis. BMC Sports Sci Med Rehabil. 2022 Jul 16;14(1):129. doi: 10.1186/s13102-022-00526-x.

Study record dates

Study Major Dates

• Study Start (Actual): May 30, 2023
• Primary Completion (Estimated): September 30, 2024
• Study Completion (Estimated): September 30, 2024

Study Registration Dates

• First Submitted: October 29, 2023
• First Submitted That Met QC Criteria: November 6, 2023
• First Posted (Actual): November 9, 2023

Study Record Updates

• Last Update Posted (Actual): November 9, 2023
• Last Update Submitted That Met QC Criteria: November 6, 2023
• Last Verified: November 1, 2023

More Information

Terms related to this study

• Keywords: Balance; Activities of Daily Living; Mobility; Independence; Untrained
• Other Study ID Numbers: NU2863

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No