Search clinical trials for: long term treatment

Total 132438 results

ONY

No longer available

Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)

Neonatal Respiratory Distress

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Long-Term Outcomes and Durability of Effect Following Treatment With Cladribine Tablets for MS (CLASSIC-MS)

Multiple Sclerosis (MS)

United States, Lebanon, Spain, Sweden, Poland, Italy, Estonia, Australia, Austria, Belgium, Bulgaria, Canada, Croatia, Czechia, Finland, France, Georgia, Germany, Korea, Republic of, Lithuania, Norway, Portugal, Romania, Russian Federation and more
Ferring Pharmaceuticals

Completed

Specified Drug Use-results Survey (Long-term Use) on MINIRINMELT® OD Tablet (Nocturia) (NOC01)

Nocturia Due to Nocturnal Polyuria

Japan
Janssen-Cilag International NV

Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

Depressive Disorder, Major

Israel, Hungary, Korea, Republic of, Taiwan, Portugal, Turkey, Germany, Malaysia, Denmark, Bulgaria, Czechia, Belgium, Poland, Brazil, Netherlands, Argentina, Finland, Greece, South Africa, Austria, Kazakhstan, Norway, Sweden, United...
Novartis Pharmaceuticals

Completed

Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC (COMPLEEMENT-1)

Breast Cancer

United States, Belgium, Canada, Italy, Spain, United Kingdom, Austria, Czechia, Hungary, Malaysia, Saudi Arabia, Taiwan, Argentina, France, Israel, Netherlands, Russian Federation, Hong Kong, Thailand, Lebanon, Bulgaria, Denmark, Po... and more
Mirum Pharmaceuticals, Inc.

Completed

Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 (Maralixibat) in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis (INDIGO)

Progressive Familial Intrahepatic Cholestasis (PFIC)

United States, United Kingdom, Poland, France
Galapagos NV
Gilead Sciences

Active, not recruiting

Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Adults With Rheumatoid Arthritis (FINCH 4)

Rheumatoid Arthritis

Spain, United States, Japan, Korea, Republic of, Taiwan, Belgium, India, Malaysia, Argentina, Australia, Poland, Czechia, Serbia, Germany, New Zealand, Bulgaria, Canada, Chile, France, Hong Kong, Hungary, Ireland, Israel, Italy, Mexico, R... and more
Regend Therapeutics
Peking Union Medical College Hospital; Ruijin Hospital; The First Affiliated... and other collaborators

Completed

Treatment of Idiopathic Pulmonary Fibrosis(IPF) by REGEND001

Idiopathic Pulmonary Fibrosis

China
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer

Prostate Cancer

United States, Canada
International Agency for Research on Cancer
Kamenge University Hospital, Burundi University, Burundi

Completed

Evaluating Thermal Ablation in the Treatment of Cervical Neoplasia

Cervical Neoplasia

Burundi
Zealand Pharma

Completed

The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short Bowel Syndrome (EASE SBS 4)

Short Bowel Syndrome

Denmark
Genentech, Inc.

Terminated

An Extension Study to Evaluate the Long-Term Safety and Tolerability of UTTR1147A in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis

Germany, Italy, Poland, Russian Federation, Serbia, United States, Ukraine, Bulgaria, Georgia, Greece, Ireland, Moldova, Republic of, Spain, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation

Cystic Fibrosis

United States, Australia, Canada, France, United Kingdom, Germany, Spain, Switzerland, Belgium, Israel, Netherlands, Denmark, Italy, Austria, Ireland, Sweden
Susan L. Greenspan
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II) (ZEST II)

Osteoporosis, Postmenopausal | Osteoporotic Fractures

United States
Actelion
Chiltern International Ltd.; Medidata Solutions; Frontier Science & Technology... and other collaborators

Terminated

A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (SERENADE OL)

Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

United States, United Kingdom, Israel, Austria, Russian Federation, Germany, Poland, Denmark, Argentina, Brazil, Bulgaria, France, Hungary, Romania, Sweden
Fate Therapeutics

Terminated

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Melanoma | Lymphoma | Renal Cell Carcinoma | Cervical Cancer | Head and Neck Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumor | Small-cell Lung Cancer | HER2-positive Breast Cancer | Pancreas Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability and other conditions

United States
Vertex Pharmaceuticals Incorporated

Completed

Long-term Safety of Lumacaftor/Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

Cystic Fibrosis

United States, Canada
Astellas Pharma Global Development, Inc.

Completed

A Study to Find Out How Safe Long-term Treatment With Fezolinetant is in Women With Hot Flashes Going Through Menopause (Skylight 4)

Hot Flashes

United States, Czechia, Canada, Latvia, Poland, Spain, Ukraine, United Kingdom
Asana BioSciences

Terminated

Study to Evaluate Long-Term Safety of ASN002 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada
First Affiliated Hospital, Sun Yat-Sen University

Completed

The Long-term Efficacy of Imatinib With Hepatic Resection or Other Local Treatment for GIST Liver Metastases

Liver Metastases | GIST, Malignant

China
Regeneron Pharmaceuticals

Enrolling by invitation

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

Retinopathy of Prematurity

United States, Bulgaria, Colombia, Korea, Republic of, Romania, Russian Federation, Taiwan, Thailand, Turkey, Vietnam
Hospital Mutua de Terrassa
Hospital Clinic of Barcelona; Hospital Universitario Ramon y Cajal; Hospital... and other collaborators

Active, not recruiting

Long-term Study of Endoscopic Treatment of Stenosis in Crohn´s Disease (Long-ProtDilat)

Crohn Disease | Stenosis

Spain
AO GENERIUM

Completed

Prospective Observational Study of Long-term Pathogenic Treatment of Elizaria® (NAP)

Paroxysmal Nocturnal Hemoglobinuria

Russian Federation
Nanjing First Hospital, Nanjing Medical University

Enrolling by invitation

Mid-and Long-term Efficacy of Ergot Alkaloids in the Treatment of Salivation in Patients With Parkinson's Disease.

Main Heading (Descriptor) Terms

China
Boehringer Ingelheim

Completed

A Follow-up Study Investigating Long Term Treatment With Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD)

Lung Diseases, Interstitial

United States, Spain, Belgium, Canada, Korea, Republic of, Germany, United Kingdom, Japan, China, France, Italy, Chile, Poland, Russian Federation, Argentina
SecuraBio

Completed

A Long-term, Continued Treatment and Follow-up Study in Participants With Hematologic Malignancies Treated With Duvelisib (IPI-145)

Hematologic Malignancy

United States, Italy
Klaipėda University
Research Council of Lithuania

Active, not recruiting

The Effectiveness of Natural Resources for Reducing Stress (LUGISES)

COVID-19 | Distress, Emotional

Lithuania
University of Cagliari

Completed

Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.

Polycystic Ovary Syndrome
GlaxoSmithKline
PPD

Active, not recruiting

Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

Pulmonary Disease, Chronic Obstructive

United States, Australia, Argentina, Canada, France, Germany, Japan, Poland, Spain, Hungary, Belgium, Netherlands, Israel, Mexico, Austria, Korea, Republic of, China, Greece, Denmark, India, Sweden, Taiwan, United Kingdom, Italy, Brazil, New... and more
Peter MacCallum Cancer Centre, Australia

Completed

COVID-19 Prevention and Treatment in Cancer; a Sequential Multiple Assignment Randomised Trial; (C-SMART)

Cancer | Covid19 | Respiratory Viral Infection

Australia
Greater Houston Retina Research
Regeneron Pharmaceuticals; Clinical Trials Resource Group, LLC

Active, not recruiting

Long-Term Efficacy and Safety of Intravitreal Aflibercept Injections for the Treatment of Diabetic Retinopathy for Subjects Who Completed the 2-Year PANORAMA Trial (VOYAGE)

Diabetic Retinopathy

United States, Puerto Rico
Galapagos NV
Gilead Sciences

Terminated

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease (DIVERSITYLTE)

Crohn's Disease

Hong Kong, United States, Netherlands, Belgium, Israel, Spain, Korea, Republic of, Taiwan, Germany, Australia, Italy, India, Singapore, Portugal, France, Malaysia, New Zealand, Ireland, Poland, Romania, Japan, Croatia, Iceland, United... and more
H. Lundbeck A/S

Active, not recruiting

Long-Term Extension Study With Eptinezumab as Preventive Treatment in Participants With Migraine in Japan

Migraine

Japan
Helwan University

Active, not recruiting

Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)

Benign Prostatic Hyperplasia

Egypt
St. Jude Children's Research Hospital

Suspended

Reduced Intensity Transplantation for Severe Sickle Cell Disease

Sickle Cell Disease

United States
SyMap Medical (Suzhou), Ltd.
JieNuo Medical(Beijing)Co.,Ltd

Active, not recruiting

Bronchial Ablation for Treatment of Asthma (BATA) Trial (BATA)

Asthma

China
Takeda
Takeda Development Center Americas, Inc.

Active, not recruiting

Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age

Hunter Syndrome

United States, Germany, Malaysia, Philippines, Thailand, Dominican Republic, Serbia, Vietnam
Incyte Corporation

Completed

Assess the Long Term Efficacy and Safety of Ruxolitinib Cream in Participants With Vitiligo

Vitiligo

United States, Canada, Poland, Spain, Germany, Bulgaria, France, Netherlands
Spectrum Health Hospitals
EKOS Corporation

Completed

Long Term Effects of Treating Submassive Pulmonary Embolism With Ultra-sound Accelerated Thrombolysis (SPEAR)

Submassive Pulmonary Embolism

United States
Boehringer Ingelheim

Active, not recruiting

NICEFIT-ON: A Study Under Routine Clinical Practice in Taiwan to Observe the Long-term Outcome of People With Certain Types of Lung Disease (PF-ILD, SSc-ILD, IPF) Who Start Treatment With Nintedanib

Idiopathic Pulmonary Fibrosis

Taiwan
Butler Hospital
American Foundation for Suicide Prevention

Completed

Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders (CLASP-S)

Schizophrenia | Suicide

United States
Ipsen
University of Oklahoma

Completed

Long-Term Treatment With rhIGF-1 in GHIS

Growth Hormone Insensitivity Syndrome

United States
Bayer

Completed

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug (RE-THINc ESRD)

End Stage Renal Disease Requiring Hemodialysis

Belgium, United States, Latvia, Taiwan, Germany, Japan, Spain, Canada, Bulgaria, Greece, Ukraine, Czechia, Hungary, Korea, Republic of, Russian Federation
Apellis Pharmaceuticals, Inc.

Active, not recruiting

Pegcetacoplan Long Term Safety and Efficacy Extension Study

PNH

United States, France, Germany, Canada, United Kingdom, Belgium, Hong Kong, Japan, Singapore, Thailand, Russian Federation, Serbia, Australia, Bulgaria, Spain, Malaysia, Korea, Republic of, Colombia, Mexico, Peru, Philippines
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma

Lymphoma

United States, Canada, South Africa
GC Cell Corporation

Completed

Long Term Follow-Up Study of Immuncell-LC Group and Non-Treatment Group in Hepatocellular Carcinoma Patients. (Immuncell-LC)

Hepatocellular Carcinoma

Korea, Republic of
Galderma R&D

Completed

Long-term Treatment of Moderate to Severe Glabellar Lines and Lateral Canthal Lines (READY-4)

Lateral Canthal Lines | Glabellar Lines

United States, Puerto Rico
Radius Pharmaceuticals, Inc.
Benuvia Therapeutics Inc.

Terminated

Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures

Childhood Absence Epilepsy

United States
Merete Haedersdal

Completed

Longevity of Microwave Thermolysis and Botulinum Toxin A for Treatment of Axillary Hyperhidrosis

Hyperhidrosis Primary Focal Axilla

Denmark
Pfizer

Completed

Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of Migraine

Acute Migraine

United States

Search clinical trials for: long term treatment

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