Search clinical trials for: moderate to severe ulcerative colitis

Total 477384 results

ActoGeniX N.V.

Completed

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Moderately Active Ulcerative Colitis

Canada, Netherlands, Sweden, Belgium
GlaxoSmithKline

Terminated

GI-270384 Study In Patients With Mild To Moderate Ulcerative Colitis

Ulcerative Colitis
Cosmo Technologies Ltd

Completed

Efficacy and Tolerability of a New Oral Extended-Release Formulation Containing Parnaparin Sodium, Administered Add-on Therapy

Ulcerative Colitis
University Health Network, Toronto
Crohn's and Colitis Foundation

Terminated

Effect of Iron and Vitamin E Supplementation on Disease Activity in Patients With Either Crohn's Disease or Ulcerative Colitis

Crohn's Disease | Ulcerative Colitis | Mild or Moderate Anaemia

Canada
Alizyme

Completed

Study of COLAL-PRED® in the Treatment of Moderate Acute Ulcerative Colitis

Ulcerative Colitis

Spain, Belgium, Denmark, United Kingdom, South Africa, Israel, France, Australia, Sweden, Italy, Poland, Czech Republic, Germany, Hungary, Russian Federation
Hospital Universitario La Paz
Hospital Universitario del Henares, Madrid, Spain

Not yet recruiting

CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea (CPAPLIP)

Dyslipidemias | Sleep Apnea | Hyperuricemia
AbbVie

Not yet recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

Atopic Dermatitis
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

Clinical Study of Trilinolein Cream for Prevention of Relapse in Remission of Moderate-to-severe Atopic Dermatitis.

Atopic Dermatitis
AbbVie

Not yet recruiting

Study of Oral Upadacitinib to Assess Change in Disease Activity and Adverse Events in Adult Participants With Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis
RemeGen Co., Ltd.

Not yet recruiting

A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)

Systemic Lupus Erythematosus
Abivax S.A.

Not yet recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease (ENHANCE-CD)

Moderately to Severely Active Crohn Disease
AstraZeneca

Not yet recruiting

Phase IIa Study Evaluating AZD7798 in Crohn's Disease (AMALTHEA)

Moderate to Severe Crohn's Disease

United States, Vietnam, Turkey, Malaysia, Taiwan, Spain, Germany, Italy, Chile, Slovakia, Brazil, Japan, Bulgaria, Ukraine, South Africa, Argentina, Australia, Romania, Austria, Mexico, Sweden
Qilu Pharmaceutical (Hainan) Co., Ltd.

Recruiting

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
CHU de Reims

Not yet recruiting

Prevalence and Factors Associated With Sleep Disorders in Inflammatory Bowel Disease (SOMMICI)

Sleep Disorder | Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

France
Regina Elena Cancer Institute

Recruiting

Analysis and Evaluation of Smoking Treatment With Cytisine

Moderate or Severe Tobacco Use Disorder

Italy
Wuhan Union Hospital, China

Recruiting

Efficacy and Safety of Ganciclovir Capsules in the Treatment of Refractory Moderate-to-severe Allergic Rhinitis

Rhinitis, Allergic

China
Apollo Therapeutics Ltd

Recruiting

A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis

Dermatitis | Eczema | Atopic Dermatitis | Atopic | Eczema, Atopic | Dermatologic Disease | Eczema Atopic Dermatitis

United States, Canada
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Merck Sharp & Dohme LLC

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Crohn's Disease
University of North Carolina, Chapel Hill
University of Pennsylvania; Centers for Disease Control and Prevention

Not yet recruiting

Improving Outcomes and Reducing Disparities for Patients With Inflammatory Bowel Disease Through Epidemiology and Enhanced Disease Management (PROMOTE IBD)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Colitis

United States
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Ustekinumab in Children and Adolescents From 6 Years to Less Than 18 Years of Age With Moderate to Severe Plaque Psoriasis (BE TOGETHER)

Moderate to Severe Plaque Psoriasis

United States
Xie Kangjie

Recruiting

Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia

Pharmacokinetics | Hypoproteinemia | Ciprofol

China
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
AstraZeneca

Recruiting

A Study To Evaluate The Treatment Pattern Of Moderate-to-Severe Asthma Patients In China (PRESENT)

Moderate-to-Severe Asthma

China
AbbVie

Recruiting

An Observational Study to Assess Real-World Use of Upadacitinib Tablets in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis in China (REACH-AD)

Atopic Dermatitis

China
Haisco Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of HSK16149 Capsule in the Treatment of Moderate and Severe Central Neuropathic Pain in China

Central Neuropathic Pain
Brigham and Women's Hospital

Not yet recruiting

Treatment of UC With Novel Therapeutics (TURTLE)

Ulcerative Colitis | Ulcerative Colitis Mild

United States
The Second Hospital of Nanjing Medical University
Heilongjiang University of Chinese Medicine

Recruiting

Effect and Mechanism of Baitouweng Decoction for Large Intestine Damp-heat Syndrome of Ulcerative Colitis

Ulcerative Colitis

China
China National Center for Cardiovascular Diseases

Not yet recruiting

Exploring the Clinical Efficacy of Remote Management Applications Through Comprehensive Physical Therapy for Patients With Moderate to Severe Sleep Apnea

Aerobic Exercise | M-health | OSAHS | Oropharyngeal Muscle Training | Comprehensive Physical Therapy
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Pharmacological Effect of a Single Intravenous Infusion of Belantamab in Male and Female Participants Aged 18 to 75 With Moderate to Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States
MoonLake Immunotherapeutics AG

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
MoonLake Immunotherapeutics AG

Recruiting

Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
IRCCS San Raffaele

Recruiting

Non-invasive Assessment of RECTUM (POUCH) by US (RECT-US) in a Cohort of IBD Patients (RECT-US)

Crohn's Disease | Ulcerative Colitis

Italy
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Takeda

Not yet recruiting

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis
Dalhousie University
Alzheimer Society of Canada

Not yet recruiting

Dementia Moves: Protocol for a Feasibility Study

Moderate to Severe Dementia
Taizhou Mabtech Pharmaceutical Co.,Ltd

Not yet recruiting

Comparative Study of CMAB015 and Secukinumab for Patients With Moderate to Severe Plaque Psoriasis

Psoriasis
Oneness Biotech Co., Ltd.

Not yet recruiting

Evaluate Efficacy, Pharmacokinetics, and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
AbbVie

Not yet recruiting

A Study to Assess the Effect of Upadacitinib in Atopic Dermatitis-induced Sleep Disturbance in Adults With Moderate to Severe Atopic Dermatitis (Sleep Up)

Sleep Disturbance | Atopic Dermatitis
Lebanese University

Recruiting

Effect of Probiotic Administration on Patients With Inflammatory Bowel Disease

Quality of Life | Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Food Intolerance | Flare Up

Lebanon
AbbVie

Recruiting

A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab (Switch-Up)

Atopic Dermatitis

United States
Diabetes Foundation, India
National Diabetes Obesity and Cholesterol Foundation

Recruiting

Comparison of Micro- and Macrovascular Disease(s) in People With T2D, Who Have Moderate to Severe Acanthosis Nigricans vs. Those Who do Not Have Acanthosis Nigricans

Type 2 Diabetes Mellitus With Complication

India
University of California, San Diego
Mayo Clinic; National Heart, Lung, and Blood Institute (NHLBI); Yale University; Brigham and Women's Hospital and other collaborators

Recruiting

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping (EPIPHANY)

Moderate to Severe Asthma

United States
Akeso

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of AK120 in Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Indivior Inc.

Recruiting

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Opioid Use Disorder

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Clinical Trial of Microneedle Radiofrequency Combined With Oral Isotretinoin in Moderate to Severe Acne

Moderate to Severe Acne Vulgaris

China
Regeneron Pharmaceuticals
Intellia Therapeutics

Not yet recruiting

A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B (BEYOND-9)

Hemophilia B
Amgen

Recruiting

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Asthma

United States
Laboratoires Thea

Not yet recruiting

Comparison of the Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome.

Dry Eye Syndrome

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