Search clinical trials for: refractory graft versus host disease

Total 391231 results

Chinese University of Hong Kong

Recruiting

Safety and Efficacy of Fecal Microbiota Transplantation

Alcohol Dependence | Multiple Sclerosis | Obesity | Diabetes Mellitus | Hepatic Encephalopathy | Irritable Bowel Syndrome | Constipation | Celiac Disease | Crohn Disease | Ulcerative Colitis | Liver Disease | Idiopathic Thrombocytopenic Purpura | Clostridium Difficile Infection | Alopecia | Autism | Multiple Organ Dysfunction... and other conditions

Hong Kong
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Optimizing PTCy Dose and Timing

Hematologic Neoplasms | Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Recruiting

Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia | Myelodysplastic Syndrome

United States
Centre Hospitalier Universitaire de Besancon

Recruiting

Lipopolysaccharide Metabolism and Identification of Potential Biomarkers Predictive of Graft-versus-host Disease After Allogeneic Stem Cell Transplantation (MetAlloLip)

Hematologic Diseases | Stem Cell Transplantation

France
National Institute of Allergy and Infectious Diseases...

Recruiting

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Chronic Granulomatous Disease

United States
Assistance Publique - Hôpitaux de Paris
Imagine Institute; Axonal-Biostatem; CERBA laboratory; SATT; SNC Graft Versus Host...

Recruiting

Evaluation of a Donor Testing Kit for the Prediction of AGVHD in Patient Receiving a Peripheral Blood Stem Cell Allograft (Predictor2)

Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia in Remission | Lymphoma in Remission | Non-progressive Myeloproliferative Syndrome | Myelodysplasia With Stable Blasts is Cell Number and < 10% of Blastocysts | Acute Leukemia Biphenotypic in Remission

France, Germany, Belgium
University of Liege
Belgian Hematological Society

Recruiting

Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning (HLA)

Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Non Hodgkin Lymphoma | Myeloproliferative Disorder | Chronic Lymphoid Leukemia | Acute Myeloid Leukemia in Remission | Myeloproliferative Syndrome | Chronic Myeloid Leukemia in Remission | Acute Lymphoid Leukemia in Remission

Belgium
University of Michigan Rogel Cancer Center
National Institutes of Health (NIH); National Center for Advancing Translational...

Recruiting

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Follicular Lymphoma | Myelodysplastic Syndromes | Hematologic Diseases | Mantle Cell Lymphoma | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | Graft Vs Host Disease | Acute Leukemia in Remission | Graft-versus-host-disease | Chronic Myelogenous Leukemia - Chronic Phase | Chronic Myelogenous Leukemia... and other conditions

United States
Medical University of Graz

Recruiting

Fecal Microbiota Transplantation in aGvHD After ASCT

Graft Versus Host Disease in GI Tract

Austria
Hospital Israelita Albert Einstein

Recruiting

Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies

Graft Versus Host Disease | Infection Viral | Bone Marrow Transplant Complications | Engraft Failure | Immunologic Suppression

Brazil
CSL Behring

Recruiting

The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant (MODULAATE)

Acute-graft-versus-host Disease

United States, Korea, Republic of, Spain, Australia, Germany, Italy, Turkey, Japan
University Hospital, Basel, Switzerland

Recruiting

Nintedanib in Patients With Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem Cell Transplantation (NINBOST2018)

Bronchiolitis Obliterans Syndrome (BOS) | Bronchiolitis Obliterans (BO)

Switzerland, Saudi Arabia
Equillium
Biocon Limited

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD (EQUATE)

GVHD | GVHD, Acute | aGVHD | Acute-graft-versus-host Disease

United States
National Institute of Dental and Craniofacial Research...

Recruiting

Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

Graft Versus Host Disease

United States
University of Kansas Medical Center
In8bio Inc.

Recruiting

Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia

United States
AHS Cancer Control Alberta

Recruiting

HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis (ATG2017)

Relapse | Graft-versus-host-disease

Canada
University Hospital, Lille

Recruiting

Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease (IMMUNO-PEC)

Graft Versus Host Disease | Extracorporeal Photopheresis

France
CellSight Technologies, Inc.
Stanford University

Recruiting

Detection of Graft Versus Host Disease With [18F]F-AraG

Graft Versus Host Disease

United States
Sheba Medical Center

Recruiting

Anti T-lymphocyte Immunoglobulin With Post Transplant Cyclophosphamide to Prevent GVHD Post Allogeneic Transplantation

Graft Versus Host Disease

Israel
The First Affiliated Hospital of Soochow University

Recruiting

Fecal Microbiota Transplantation in Gut aGVHD Treated

Acute-graft-versus-host Disease

China
The First Hospital of Jilin University

Not yet recruiting

The Effect of Human Leukocyte Antigen Macthing on Guiding Tacrolimus Regimen After Liver Transplantation

Liver Transplantation | Drug-Related Side Effects and Adverse Reactions | Graft Rejection | Graft Versus Host Disease
Washington University School of Medicine

Recruiting

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Hemoglobinopathies | Bone Marrow Failure Syndromes | Metabolic Disorders | Non-malignant Disorders | Severe Sickle Cell Disease | Immunologic Disorders

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
Washington University School of Medicine

Recruiting

Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

Chronic GVHD | Acute Graft-versus-host Disease | Chronic Graft-versus-host Disease | Acute GVHD

United States
Novartis Pharmaceuticals

Recruiting

CINC424A2X01B Rollover Protocol

Acute Myeloid Leukemia | Primary Myelofibrosis | Polycythemia Vera | Thalassemia | Graft Versus Host Disease

Korea, Republic of, Italy, Belgium, Germany, Australia, Bulgaria, Chile, China, Denmark, Greece, Hungary, Israel, Lebanon, Poland, Portugal, Russian Federation, Slovakia, South Africa, Spain, Sweden, Thailand, India, Japan, Mexico, Turkey, Fran...
Ohio State University Comprehensive Cancer Center

Recruiting

Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease

Acute Graft-versus-Host Disease | Allogeneic Stem Cell Transplant

United States
University of Liege
KU Leuven; Maastricht University Medical Center; University Hospital, Ghent; Queen... and other collaborators

Recruiting

Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function

Graft-versus-host Disease | Poor Graft Function | Low Donor T-cell Chimerism

Belgium, Netherlands
National Institute of Allergy and Infectious Diseases...

Recruiting

Evaluation of Patients With Immune Function Abnormalities

Chronic Granulomatous Disease (CGD) | X-Linked Severe Combined Immune Deficiency (XSCID) | Leukocyte Adhesion Deficiency 1 (LAD) | Graft Versus Host Disease (cGvHD)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants

Graft vs Host Disease | Graft Rejection | Graft-versus-leukemia

United States
National Cancer Institute (NCI)

Recruiting

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

Chronic Graft vs. Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)
New York University and New York Genome Center

Recruiting

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

Graft-Versus-Host Disease | Graft-versus-leukemia | Donor Apheresis

United States
National Institute of Allergy and Infectious Diseases...

Enrolling by invitation

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Severe Combined Immune Deficiency (SCID)

United States
Washington University School of Medicine
National Cancer Institute (NCI); Incyte Corporation; American Society of Hematology

Completed

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Myelodysplastic Syndromes | Hodgkin Disease | Non-Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
National Cancer Institute (NCI)

Active, not recruiting

Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease

Chronic GVHD

United States
National Cancer Institute (NCI)

Suspended

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies in People Living With HIV

HIV | Hematologic Malignancies

United States
Medical College of Wisconsin

Completed

Tildrakizumab for Prevention of Acute Graft-Versus-Host Disease

Hematologic Malignancies

United States
Tabriz University of Medical Sciences
SCARM Institute, Tabriz, Iran

Completed

Effect of PMSCs and Their Secretome for the Treatment of GvHD (GvHD)

GVHD

Iran, Islamic Republic of
Janssen Research & Development, LLC
Pharmacyclics LLC.

Enrolling by invitation

A Long-term Extension Study of PCI-32765 (Ibrutinib) (CAN3001)

Follicular Lymphoma | Chronic Graft Versus Host Disease | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Small Lymphocytic Lymphoma

United States, Spain, United Kingdom, Israel, Canada, Belgium, Poland, China, Japan, France, Australia, Russian Federation, Turkey, Sweden, Italy, Mexico, Czechia, Korea, Republic of, Ukraine, Brazil, Hungary, Portugal, Argentina, Col... and more
Syndax Pharmaceuticals

Active, not recruiting

A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD) (AGAVE-201)

Chronic Graft-versus-host-disease

Korea, Republic of, United States, Spain, Taiwan, France, Singapore, Belgium, Germany, Italy, Canada, Israel, Australia, United Kingdom, Greece, Poland, Portugal
Monica Bhatia

Completed

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

Sickle Cell Disease | Graft Versus Host Disease

United States
St. Jude Children's Research Hospital

Active, not recruiting

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency

United States
Novartis Pharmaceuticals

Active, not recruiting

Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplant

Graft vs Host Disease

Japan, Slovakia, Taiwan, Spain, Korea, Republic of, Thailand, Canada, Russian Federation, Italy, Turkey, India, Czechia, Brazil, Switzerland
M.D. Anderson Cancer Center
Incyte Corporation

Active, not recruiting

Itacitinib for the Prevention of Graft Versus Host Disease

Hematologic and Lymphocytic Disorder

United States
Roswell Park Cancer Institute

Active, not recruiting

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Myeloproliferative Neoplasm | Minimal Residual Disease | Graft Versus Host Disease | Severe Aplastic Anemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia... and other conditions

United States
Scripps Translational Science Institute
Cue Health

Active, not recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
Regimmune Corporation

Completed

RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation

Graft Vs Host Disease | Graft-versus-host-disease | Acute-graft-versus-host Disease | Prevention of aGVHD

United States
University of Liege
University Hospital, Gasthuisberg; University Hospital, Ghent; University Hospital... and other collaborators

Active, not recruiting

Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens

Hematological Malignancies | Graft-Versus-Host Disease

Belgium
St. Petersburg State Pavlov Medical University

Active, not recruiting

PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT (PTCyRuxo)

Acute Myeloid Leukemia | Acute Lymphoid Leukemia | Stem Cell Transplant Complications | Graft-versus-host-disease

Russian Federation
Hoffmann-La Roche
NSABP Foundation Inc; German Breast Group

Active, not recruiting

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Breast Cancer

United States, Italy, United Kingdom, Canada, Czechia, Argentina, Austria, Belgium, Brazil, China, France, Germany, Guatemala, Ireland, Panama, Spain, Sweden, Taiwan, Turkey, Colombia, Hong Kong, Peru, Switzerland, South Africa, Israel, G... and more

Search clinical trials for: refractory graft versus host disease

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